WO2010100212A1

WO2010100212A1 - Multifunctional mixing device for laboratory operation

Info

Publication number: WO2010100212A1
Application number: PCT/EP2010/052725
Authority: WO
Inventors: Heyo Mennenga; Armin Winkler; Jan Michael Heinrich; Christoph Mohr
Original assignee: RATIONAL Technische Lösungen GmbH
Priority date: 2009-03-05
Filing date: 2010-03-03
Publication date: 2010-09-10
Also published as: DE102009011987A1; WO2010100212A9

Abstract

The invention relates to a multifunctional mixing device laboratory operation, said device being provided for samples in small, closed containers or small, unclosed containers that are open at the top. The multifunctional mixing device can be used in conjunction with a drive device for a magnet stirrer or with a separate drive, wherein the rotational motion of the vertical axis (5) is converted into one or two horizontal axial rotational motions. The multifunctional mixing device is characterized in that various auxiliary apparatuses are arranged on the horizontal axis (8) on one or both sides by means of coupling elements in order to fulfill various mixing tasks, such as rotating, tilting, seesawing, or roll tilting, or further drive elements are connected. The coupling elements are constructed as detachable, in particular magnetic, joints, the angle of which can be adjusted. The joints can be adjusted at an angle of 0° to 90°.

Description

Multifunction mixer for laboratory use

description

The invention relates to a multi-function mixing device for samples in small, sealed or not closed, then open-top containers in the laboratory.

State of the art

The mixing, also dispersing, suspending and emulsifying liquids (samples, reaction mixtures), which are in containers, is a very common process in chemical, medical, biochemical, pharmaceutical, biological and other laboratories.

Numerous embodiments of mixing devices are known. Their function is to spatially and dynamically move containers with the components to be mixed in such a way that the flow phenomena caused by the changed direction of gravity lead to the movement of the liquids contained in the containers, with which is connected:

- the mixing of different liquids,

the intensive and frequent contact of particles which are in the liquid with the liquid (for example in order to improve the dissolution of the particles) or of the particles with each other (for example to establish the contact between particles),

- The cyclical flooding of solid areas in the vessels, as they represent, for example cell cultures, which causes a constant refreshment of directly related to the cell culture liquid layer as well as a constant change of contact, for example, the cell culture with liquid and the gas contained in the vessel. It differs depending on the movement of the mixing devices

Containers, rotary mixers, rolling mixers, rotary-roll mixers, tilting mixers, vibrating mixers. Ping-pong mixer, tumble mixer. In some devices, the described forms of motion can be combined. Mixers are sometimes referred to as a shaker or blender.

There are a great many mixers have been proposed and introduced to the market. In the magnetic stirrers normally moves the application of these devices, a rotating magnetic field generated by them a then co-rotating, usually encapsulated magnet in a set on the magnetic stirrer vessel, which moves the liquid in the vessel by its movement and mixes. The moving, touching parts with or with the magnets in their interior are called Rührfischchen, in jargon also submarine, stirrer, Rührmaus or Stirrhwein.

The magnetic rotating field is generated by motor-driven, rotating about a vertical axis magnets or switched by the magnetic field electric coils. These coils are fixedly arranged in a circle and are switched electronically alternately so that results in a magnetic rotating field. The rotating field acts through the magnetic stirrer setting plate and, in normal use, on the stirrer or stir bar (e.g., DE 102006024300 B4).

It is also known to use this rotating field in addition to the movement of the so-called Rührfischchen alternatively for driving a laboratory pump, as shown in DE 4421431 C2.

EP 676234 A1 discloses a mixing device for laboratory use, which is intended for use with a drive of a magnetic stirrer. The device comprises a base element and an outer element, wherein the outer element is arranged obliquely but at a fixed angle relative to the base element, and Sample tubes are inserted into a clamping device. Another embodiment shows the arrangement of the outer element to the base of 90 degrees and includes a plurality of rollers which are rotatably mounted and can be placed on soft sample tubes.

US 3980227 A and US 5266273 A show devices with their own drive element for moving vials or cuvettes in only two selectable directions of movement, once in an inclined position for mixing the samples and on the other with a mild centrifugal force.

The known mixing devices are on the one hand consuming and therefore expensive, and they are not sufficiently universal. Multiple mixers, as required to achieve a variety of mixing operations required in the laboratories, are associated with not inconsiderable costs and take away much of the laborious space in laboratories. The range of adjustable mixing parameters is low.

Presentation of the invention

It is the task of producing a simple, thus very cost-effective multi-function mixing device, which offers many mixing movements for a variety of vessel shapes by variability and modularity and thus is very universal.

The multi-function mixing device according to the invention for laboratory operation is provided for samples in small, sealed or not closed, open-topped containers. It can be used in conjunction with a drive device for a magnetic stirrer or with its own drive, wherein the rotational movement of the vertical axis is converted into one or two horizontal axial rotational movements. The multi-function mixer is characterized in that on the horizontal axis on one or both sides via coupling elements various auxiliary devices are arranged to perform various mixing tasks, such as turning, tilting, rocking or roll-tilting, or are coupled to further drive elements. The coupling elements are constructed as detachable, in particular magnetic, angularly adjustable joints. The joints are adjustable at an angle of 0 ° to 90 °.

In one embodiment, the angle-adjustable joints in the form of a bent coupling is designed, which consists of two magnets, wherein one of the magnets recessed in a bore is arranged and the other magnet protrudes from the coupling element, wherein in the coupled state of the other Magnet in the first hole holds and both magnets tighten.

The conversion of the vertical rotational movement in one or two horizontal axial rotational movements takes place by a worm gear drive in which the gear carries one or more magnets, so that a temporally variable in strength, decreasing and swelling magnetic field outside of Housing is created. A rocker located above the housing, which is rotatably mounted about a guide axis and at the opposite end supported by a spring, consists of ferromagnetic material or has one or more magnets.

The horizontal axis carries in one embodiment an eccentric, which is connected via an arm and a pivot bearing in operative connection with a support plate which is rotatably supported on one side via a shaft.

As holding elements for the small, closed or not closed, open-topped containers on the rocker or on the carrier plate adhesive films may be arranged.

In another embodiment, the rotational movement of the horizontal axis is transmitted by means of a magnetic coupling to elements outside of a hermetically sealed housing, in the way that Magnets or ferromagnetic elements are connected to the gear inside the hermetically sealed housing and outside the housing a fixed, non-rotating bearing pin, which lies in the alignment of the horizontal axis, a coupling part receives, which also contains magnets or ferromagnetic elements, which upon rotation of the Gear are taken by the magnetic force effects.

The advantages of the invention are as follows: simple addition of the already existing in laboratories magnetic stirrers, which are extended to the function of a turn-tilt mixer; modular attachable units;

Non-powered device without electrical connection, which requires no approval and no cyclical monitoring;

But also the possibility of a simple design as a motorized device; multiple blending modes with a simple device; very inexpensive and universally usable.

Brief description of the illustrations

The invention will be explained in more detail with reference to drawings. 1 shows an embodiment with screw and gear without own active drive, which takes place via the rotating magnetic field of an external magnetic stirrer,

Figure 2a, b two embodiments of a kinkable coupling, Figure 3 shows a first embodiment of a tilting or rocking mixer, Figure 4 shows an embodiment in which instead of the pairing worm shaft a friction gear application is used, Figure 5 is a clutch in the force path, the hermetically sealed housing allows FIG. 6 shows a mixing device with combination drive and with a further embodiment of the tilting or tilting mixer,

FIG. 7 shows a mixing device alone with motor drive and mounted tilting or tilting mixer,

8 shows a side view of the mixing device according to FIG. 7, FIG. 9 shows a mixing device with rocker with adhesive coating, and FIG. 10 shows a hermetically sealed mixer (closed housing) with motor drive.

Embodiment of the invention

The multi-function mixing device according to the invention can be used in connection with a drive device for a magnetic stirrer or with its own drive. In this case, a vertical rotational movement is converted into one or two horizontal axial rotational movements. Known means for this implementation are, for example, a worm gear and a gear, a pair of bevel gears, a friction gear or a traction mechanism.

FIG. 1 shows a first exemplary embodiment. The housing that encloses the shafts, the worm and the gear and fix their bearing elements is not shown here.

Shown is an inventive mixing device without its own drive but with magnetic drive elements, which, when the mixer shown is placed on a magnetic stirrer with its rotating magnetic field, are offset by the coupling of the magnetic fields in rotation.

In the magnetic stirrers normally moves the application of these devices generated by them, rotating magnetic field then a co-rotating, usually encapsulated magnet in a set on the magnetic stirring vessel, which moves the liquid in the vessel by its movement and mixes. The moving, touching Parts in the liquid with or with the magnets are called Rührfischchen, in jargon also submarine, stirrer, Rührmaus or Stirrhwein.

The magnetic rotating field of a magnetic stirrer is generated by motor-driven, rotating about a vertical axis magnets or switched by the magnetic field electric coils. These coils are fixedly arranged in a circle and are switched electronically alternately so that results in a magnetic rotating field. The rotating field acts through the adjusting plate of the magnetic stirrer, in the normal application to the Rührfischchen.

The embodiment of Figure 1 has the following features. A small bar 1, the magnetic carrier, has magnets 14 distributed symmetrically with respect to the central axis in a horizontal plane. This beam is located close to the pitch of the magnetic stirrer and thereby approximately in the middle of the rotating magnetic field and is symmetrically connected to a vertical axis 5. This vertical axis 5 has a worm, a worm gear 6, which is rotated by the rotating magnetic field. This gear screw 6 is arranged such that it acts on at least one gear 7 with a horizontal axis 8 and thus rotates in its rotation, this axis 8 with high reduction and associated torque increase. The horizontal axis 8 of the gear 7 may have one or more further rotation of the clutches. The axis 8 may have on one or both sides coupling elements or couplings for the attachment of different brackets of the container to be mixed or further drive elements.

These brackets can be performed very differently in a known manner, as a look in catalogs for known mixer shows.

Because different commercial magnetic stirrers different

Magnets can have distances, also several magnets can be mounted on different radii on the beam or the beam takes the form of a cross with two or more arms, wherein on the ends of the arms of different lengths are fixed magnets. In another embodiment, the beam consists of ferromagnetic material and only the magnets of the magnetic agitator generate the entraining forces.

Preferably, the axle 8 has on at least one side outside its bearings 10 in itself or in a connecting element, e.g. a coupling to a kink 11, which is preferably designed as an adjustable joint, which is adjustable at an angle of 0 ° to 90 °. The containers 9 (laboratory tubes, sample tubes, tubes, reaction tubes with screw cap, vials, tubes, covered multi-well plates) with the content to be mixed are connected to the part of the axis 8, for example by means of clip holders, viewed from the gear 7 from behind the kink 11 lies.

If you continue the horizontal axis 8 ungeknickt continue to lie

Mixing tubes largely parallel to the axis and around the axis and have a distance from the center R. If the bending angle α is not equal to zero, the containers additionally perform a tilting movement by the angle + α during the rotation, which causes the liquid in the Container runs back and forth and mixes. This is the function of a roll-tip mixer. The rotational movement of the bent axis leads to a rotation-tilting movement of the container and thus to a good mixing of their contents. Upon rotation of the gear and thus the bent axis, the containers connected to the axle have a rotating and a tilting movement, and the function of a turn-tilt mixer is given. At a bend angle of 90 °, the mixer is a so-called overhead mixer.

The kink can be designed as a detachable and lockable mechanical joint in a variety of ways. A particularly favorable embodiment of the joint, which is to be referred to as articulated coupling, show the figures 2a and 2b. The joint, the articulated coupling, in Figure 2a consists of two magnets, such as magnetic rings 30 and 31, which are connected in a preferably on both sides the same angle of α = 0 ° ... 45 ° with both axial sides 32 and 33. In the openings of the rings is an axis 34, around which the magnetic ring farther away from the gear can rotate. This axis can also be very short, stubby or a spherical cap. The alternative embodiment (FIG. 2b) is also proposed. In this, a first magnet is recessed in a first bore and the second magnet is out of a second bore. In the coupled state, the second magnet grips into the first bore and both magnets attract, creating the clutch force. The coupling effect can be supplemented by other elements such as pins and locking elements, in which this pin engages.

The rotation of the two coupling sides against each other allows a stepless adjustment of the bending angle in the range of 0 ° to 2 α. This coupling is easily solvable by hand, for which the magnets are tilted and released in this way, so that the containers with the contents to be mixed together with their holder are removable. The removal can offer advantages when loading the holders with the containers as well as when changing brackets and / or containers. The magnetic rings or magnetic cylinders or elements connected to them may have on their circumference a scale, e.g. engraved or lasered, have, with the help of a desired angle is reproducibly adjustable. Magnets used here do not have to be designed as a ring. It is also proposed to actively magnetize only one side and to make the other side of a ferromagnetic material. -

Fig. 2b illustrates a coupling with adjustable bending angle, in which a magnet 31 itself represents the axis of rotation. Of the two round magnets 30 and 31 is one, 30, further inserted, the other, 32, something protrudes and the latter engages in the opening above the further embedded magnet. The two-sided statements such as waves or mounting are connected to the coupling parts 32 and 33. A catch 15 supports the transmission of torque. -

In one further embodiment, one side of the axle can have a connected magnetic ring whose axis of symmetry lies in the direction of the straight axis 8 and thus shows a vertical surface with a bore. This magnet allows the fixed coupling and release of the carrier of the container to be mixed by magnetic forces. There, a holder can be clicked with several containers that are normally vertical and are now mixed tilting at the mixer according to the invention by the rotation of the axis 8. Thus, the turn-tilt mixer according to the invention in addition to the tilting mixer.

In a further embodiment, a second gear is provided, which cooperates with the screw, which also has a housing mounted in the preferably horizontal axis, which preferably protrudes on the other side of the housing than the axis of the first gear. This can move more mixer tanks. On both sides of the mixer mixing vessels are then coupled.

A possible embodiment is shown in FIG 3. Above the housing of the mixer according to the invention is a kind of rocker 20, rotatably mounted and supported at the opposite end with a spring 24. This rocker 20 has approximately over the gear 7 and outside of the housing 12, a ferromagnetic material 23 or one or more magnets whose effect passes through the housing of the mixer to the outside, such that in the radial direction results in a magnetic alternating force and in the axial Direction a circumferential attractive force. If the magnet 22 connected to the toothed wheel 7 rotates, a force action between the two magnet areas which differs in intensity and with a corresponding arrangement also in the direction causes the spring to be compressed or relaxed. The rocker 20 moves thereby about its guide axis 21 lying on the rocker 20 largely transversely to the guide axis containers such Tube 25, for example, in a holder 26, learn this so that an alternating tilting movement whereby their content is mixed. This gives the function of a pure tilting mixer. -

Instead of the drive with worm and gear in the inventive solution to use other drives that cause the driven by the rotating magnetic field of the magnetic mixer rotational movement about a vertical axis in a rotational movement about a horizontal axis is implemented (or more generally, at the two axes are at an angle, preferably at right angles to each other). These are e.g. a bevel gear or a suitably designed friction gear or a traction mechanism and in particular a round belt transmission with pulleys.

FIG. 4 shows a friction gear. The beam (magnetic carrier) 1 transmits its rotation to the vertical axis 5 and this on the small friction wheel 16. The small friction wheel 16 in turn rotates the large wheel 17, which corresponds functionally to the gear 7, and by this, the horizontal axis 8 in rotation added. In this figure, the shaft bearings and the frame or housing have been omitted.

Further, a traction mechanism is applicable, wherein the belt, preferably a round belt, a groove wheel on the vertical axis and a groove wheel on the horizontal axis comprises semicircular and two other wheels or rollers belt movement from the vertical to the horizontal and vice versa redirect familiar way.

In a further proposed embodiment, Figure 5, the housing 12 of the mixer without any open passage, closed, also on the ground by the bottom plate 47, and the movement of the not here through the housing leading horizontal axis 8a is by means of a Magnetic coupling transmitted through the permeable to magnetic fields housing on external elements. The inner, located in the housing part of the magnetic coupling is preferably through Magnets 40 or ferromagnetic elements secured to the gear 7 formed. On the outside, a fixed, non-rotating bearing pin 42 (in alignment with the horizontal axis 8a) receives a coupling part 43 which contains magnets or ferromagnetic elements 41, which are entrained upon rotation of the gear 7 by the magnetic force effects, whereby the outer part 43 rotates like the inner gear 7. The coupling part 43 can directly carry the holder 44 of the tubes, but this can also be secured by a further non-rotating magnetic holder with a possible ferromagnetic part 45 and holding magnets 46 and the force path to the tube can also have a bent coupling 11, for example, as stated above with Figure 2, so as to make the mixer for tilting mixer. If the holder of the tubes to be changed with or without tubes, the coupling 43 is withdrawn from the pin 42 or the separation is - if so executed - also possible by lifting the magnet 46. The advantage of the closed design is the good cleanability up to the possibility of sterilization. The application can thus also be carried out in safety laboratories.

The asymmetric structure of the mixer leads to the other

Proposal to use the free area of the foot, e.g. there to mount brackets, are inserted into the tubes upright. -

A further advantageous embodiment of the rocker results from the following proposal in Fig. 6. A base plate 61 of the rocker engages positively over a portion of the mixer housing. An additional frictional connection is advantageously carried out by means of magnetic forces. For this purpose, the housing and the base plate 61 magnetic and / or one-sided ferromagnetic elements 67, which are largely opposite and act on each attracting. Other types of connections, such as snap or clamp connections are also among the proposed connections. Also may be a solid connection or a molding of the housing. The base plate 61 of the rocker carries receptacles for a shaft 62. About the shaft 62 is above the base plate 61 the Support plate 60 also connected to shaft receptacles with the base plate 61. The support plate 60 has an arm 63 which carries at its end a pivot bearing 64, preferably a small ball bearing. This bearing sits on the Excenterrad 65. The eccentric 65 is held by the horizontal shaft, the gear shaft, and driven by this. Arm and shaft have a distance that determines the movement. Advantageously, the eccentric 65 is placed on the coupling of the horizontal shaft. The plane of rotation of the Excenterrades 65 is horizontal. Due to the eccentric bearing the rotary bearing 64 undergoes a vertical movement, which transmits via the arm 63 to the support plate 60. On the arm 63, the support plate 60 carries out the almost vertical movement and it pivots about the axis 62, so thus performs a tilting movement about the axis 62. Tubes 69, which are located in a holder 68 and lie transverse to the shaft on the support plate 60, undergo a tilting movement. By replacing eccentric eccentric wheels, the stroke can be selected. An eccentric wheel is preferably coupled to the clutch with magnetic forces.

The mixing device can, as shown in the example of Figure 6, also be carried out without being bound to a magnetic stirrer. For this purpose, a motor 50 is inserted. The motor 50, preferably a small stepping motor, advantageously has a continuous axis 53. The one end of the motor shaft is inserted and fixed in the lower, for this purpose bored end of the vertical axis (the worm shaft) 5, preferably by gluing. As a torque arm sufficient for the small forces due to the high reduction ratio of the screw, the cables of the motor 50 through which it is supplied with energy.

On the other axle end of the motor 50 is the beam, the

Magnetic carrier, attached. When placed on an active magnetic stirrer, the magnets mounted on the beam are carried along by the rotating field and the mixer rotates. If no magnetic stirrer is available, alternatively the motor 50 can be activated. The Power is supplied via a plug-in power supply whose output voltage is fed to the electronic module 51.

Thus, the drive can be done either by placing on an active magnetic stirrer or by a motor.

A further embodiment is proposed derived in which the drive takes place solely via the motor 50, FIG. 7.

A mixer with motor has in addition to the motor 50 a

Electronics assembly 51, which provides the motor 50, the currents. In the case of a stepper motor, these are the individual phase currents that have to be switched in a specific sequence. For this purpose, the electronic module has integrated circuits, preferably a microcontroller. In an expanded version, this electronic module has further elements for inputting and / or outputting signals, eg a potentiometer for setting the speed, buttons, microphones, loudspeakers or sounders, display elements such as LEDs, IR diodes, text displays, etc. With the aid of the On and output elements information can be input and output, with which parameters of mixing operations, which controls the programmable microcontroller can be designed. Preferably, the microcontroller has a bus system such as 1-wire bus, infrared or I ² C or RS485, via the other modular components can be coupled.

A programming, program selection, parameter input and output as well as the start of actions can be done via a remote control, similar to that of a television but also via a voice input.

FIG. 8 shows a side view of the embodiment according to FIG. 7. The explanation of FIG. 7 also applies here.

FIG. 9 shows an embodiment in which the support of the tube 69 consists of an adhesive film 70 (so-called magic päd). The tubes, placed on this slide, are sufficiently strong here. Also conceivable is the use for sealed or covered microtiter plates. FIG. 10 shows a hermetically sealed mixing device (closed

Housing) with motor drive. A comparison with Fig. 5 is illustrative.

reference numeral

1. beam, magnetic carrier, with magnets of the mixing device according to the invention

2. Motor driven bar with magnets of the magnetic stirrer

3. Drive motor of the magnetic stirrer

4. Plate of the magnetic stirrer

5. Vertical axis of the mixer

6. Gear worm

7. gear

8. Horizontal gear axle with kink 11

8a - Horizontal axis inside the case

9. Container / container / tube with contents to be mixed

10. Bearing frame, frame, housing of the turn-tilt mixer

11. kink

12. housing of the mixing device according to the invention

13. Rotary axis for kink

16. Small friction wheel

17. Large friction wheel

20. Rocker

21. Guide axis, axis of rotation of the rocker

22. magnet on the gear 7th

23. Magnet on the rocker (20) ferromagnetic material

24. Spring

25. Container, tubes

26. Holder for tubes 25

27. Motion limitation for rocker 30. First magnetic ring of the articulated coupling, first cylinder magnet of the articulated coupling

31. Second magnetic ring of the articulated coupling, second cylinder magnet of the articulated coupling

32. First axis side

33. Second axis side

34. axis of rotation of the articulated coupling, guide, stub, also spherical cap

40. Coupling magnet on the gear 7

41. outer coupling magnets on the outer coupling part 43rd

42. Journal, here with spherical thrust bearing

43. Outer coupling part, rotated about the pin 42

44. Fixing the holders of the tubes

45th possible ferromagnetic part

46. Holding magnets

47. Base plate, which closes the housing 12 of the mixer according to the invention below over the plate 4 of the magnetic stirrer

50. Motor, preferably a stepper motor

51. Electronics assembly, e.g. for the control of a stepper motor

52. Cable for the supply of electrical energy, preferably from a power adapter

53. Continuous motor axis

60. carrier plate

61. Lower part of the rocker

62. Rotary axis of the rocker, connects rocker and its lower part

63. Arm on the moving part of the rocker

64. bearings

65th Excenter wheel

66. race on the Excenterrad

67. Magnetic coupling elements for non-positive connection of lower part 61 of the rocker and housing of the mixer 68. Holder for tubes on the carrier plate

69. Tube, vessel with contents to be mixed

70. Anti-slip or adhesive film ("magic päd")

Claims

claims

1. Laboratory multifunction blender for samples in small, closed or unsealed, open-topped containers, intended for use in conjunction with a magnetic stirrer or self-propelled drive, the rotation of the vertical axis being in or two horizontal axial rotational movements is converted, characterized in that on the horizontal axis (8) on one or both sides via coupling elements which are constructed as detachable, in particular magnetic, angularly adjustable joints, various additional devices are arranged to different mixing tasks, such as turning , Tilting, rocking or roll-tilting, to meet or further drive elements are coupled.

2. Multifunction mixer according to claim 1, characterized in that the adjustable joints are adjustable at an angle of 0 ° to 90 °.

3. Multifunction mixer according to claim 1 or 2, characterized in that the angle-adjustable joint is designed in the form of a bent coupling, which consists of two magnets, wherein one of the magnets recessed in a bore is arranged and the other magnet from the coupling element stands out, in the coupled state, the other magnet sums in the first hole and both magnets tighten.

4. Multifunction mixer according to claim 1, characterized in that the conversion of the vertical rotational movement in one or two horizontal axial rotational movements by a worm gear drive takes place, in which the gear (7) carries one or more magnets (22), so that a time varying in strength, swelling and swelling magnetic field outside the housing is formed and a rocker (20) located above the housing and rotatably mounted about a guide shaft (21) and supported at the opposite end by a spring (24), made of ferromagnetic material (23) or having one or more magnets.

5. Multifunction mixer according to claim 1, characterized in that the horizontal axis (8) carries a Excenterrad (65), which via an arm (63) and a pivot bearing (64) in operative connection with a support plate (60), which on one side is rotatably mounted via a shaft (62).

6. Multi-function mixing device according to one of claims 6 or 7, characterized in that as holding elements for the small, closed or not closed, upwardly open containers on the rocker (20) or on the carrier plate (60) adhesive films are arranged.

7. Multifunction mixer according to claim 1, characterized in that the rotational movement of the horizontal axis (8 a) by means of a magnetic coupling to elements outside a hermetically sealed housing (12) is transmitted in the way that magnets (40) or ferromagnetic elements with the gear (7) within the hermetically sealed housing (12) are connected and outside of the housing (12) has a fixed, non-rotating bearing pin (42) which is in alignment with the horizontal axis (8a), a coupling part (43) receives , which also contains magnets or ferromagnetic elements (41), which are taken along by rotation of the gear (7) by the magnetic force effects.