WO2010098549A2 - Automatic cell-sucking device using a thin needle - Google Patents

Automatic cell-sucking device using a thin needle Download PDF

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Publication number
WO2010098549A2
WO2010098549A2 PCT/KR2010/000968 KR2010000968W WO2010098549A2 WO 2010098549 A2 WO2010098549 A2 WO 2010098549A2 KR 2010000968 W KR2010000968 W KR 2010000968W WO 2010098549 A2 WO2010098549 A2 WO 2010098549A2
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WO
WIPO (PCT)
Prior art keywords
motor
syringe
cylinder
cells
aspirator
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PCT/KR2010/000968
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French (fr)
Korean (ko)
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WO2010098549A3 (en
Inventor
김동석
Original Assignee
Kim Dong Seok
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Publication of WO2010098549A2 publication Critical patent/WO2010098549A2/en
Publication of WO2010098549A3 publication Critical patent/WO2010098549A3/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0283Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/50Instruments, other than pincettes or toothpicks, for removing foreign bodies from the human body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B2010/0208Biopsy devices with actuators, e.g. with triggered spring mechanisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3148Means for causing or aiding aspiration or plunger retraction

Definitions

  • the present invention relates to an automatic fine needle cell aspirator, and more particularly, uniformly and reliably regardless of the individual's skill of the operator in a series of processes of aspirating and extracting cells by puncturing tissue of the body with a needle coupled to a syringe body.
  • the present invention relates to an automatic fine needle cell aspirator configured to be able to automatically suction extract cells and to accurately discharge the extracted cells by a required amount.
  • a syringe is used as a means for performing a cell test.
  • a needle is attached to the body of the body with a needle coupled to the syringe body, and the cells are sucked and extracted and smeared on a slide glass to perform a cell test.
  • the cells are sucked and extracted by puncturing the tissue of the body with a needle coupled to the syringe body.
  • the preliminary work for sucking and extracting the cells is performed by using a needle coupled to the syringe body to poke and rotate the body tissue. Repeat this several times to make the cells easier to aspirate.
  • the plunger constituting the syringe is retracted to generate negative pressure inside the syringe cylinder, and the cells are sucked out.
  • the plunger loaded in the syringe cylinder is pushed to discharge the cells extracted by the suction.
  • the discharge since the discharge is determined by the senses and habits of the hand, the discharge varies with each test, such that the discharge becomes inconsistent.
  • the automatic fine needle cell aspirator of the present invention for solving the above problems is a series of processes in which the needle is coupled to the aspirator main body, and the needle and the needle are rotated and pulled out several times by using the needle.
  • the purpose of the present invention is to provide an automatic fine needle cell aspirator that can reliably suck and extract cells irrespective of the individual skill of the operator.
  • the syringe holder portion to which the syringe is mounted in a state in which the hub is exposed from the body so that the cells are aspirated through the hub of the syringe and connected thereto A suction unit body having a suction unit cap for fixing a syringe inserted into the syringe holder unit; A cylinder handle groove is formed at the front end to engage the cylinder handle of the syringe. A rear screw is formed at the outer end of the rear end to form a male screw coupled to a female screw formed at a rear side of the inner circumferential surface of the syringe.
  • An operating tool which is rotated and moved back and forth within the space part;
  • a plunger handle groove is formed to which the plunger handle of the syringe is coupled, and is installed in a space provided inside the operating port together with a plunger handle detection sensor, and is discharged through an internal and external screw gear to a second motor installed in the space.
  • An operating tool ; And a controller for controlling the operation of the first motor and the second motor, and a first switch and a second switch for operating the first motor and the second motor.
  • the automatic fine needle cell aspirator of the present invention configured as described above, since a series of suction operations are performed automatically by the aspirator, using a needle of a syringe coupled to the aspirator body, the needle is turned and pulled out. Irrespective of the level of skill, there is an effect of uniformly and reliably aspirating cells.
  • the automatic fine needle cell aspirator of the present invention even when the cells are aspirated and extracted by a syringe cylinder, the cells can be discharged accurately and reliably in a necessary amount, thereby increasing the reliability of the cytology. It is effective in increasing the reliability of the aspiration extraction and discharge of cells, and the overall results of cytology.
  • Figure 1 is a perspective view showing the overall configuration of the automatic fine needle cell aspirator according to the present invention
  • Figure 2 is a perspective view showing the internal configuration of the automatic fine needle cell aspirator according to the present invention
  • Figure 3 is a cross-sectional view showing the internal configuration of the automatic fine needle cell aspirator according to the present invention
  • Figure 4 is an exploded cross-sectional view of the internal structure of the automatic fine needle cell aspirator according to the present invention
  • aspirator main body 2 syringe holder
  • FIG. 1 is a perspective view showing the overall configuration of the automatic fine needle cell aspirator according to the present invention
  • Figure 2 is a perspective view showing the internal structure of an automatic fine needle cell aspirator according to the present invention
  • Figure 3 is an internal configuration of an automatic fine needle cell aspirator according to the present invention 4 is a cross-sectional view showing the internal structure of the automatic fine cell aspirator according to the present invention.
  • the automatic fine needle cell aspirator includes a syringe (with the hub 46 exposed from the main body) to confirm that the cells are sucked through the hub 46 of the syringe 41 to which the needle 40 is connected.
  • a syringe holder portion (2) on which 41 is mounted and a space portion (3) connected thereto are formed, and an aspirator provided with an aspirator cap (30) for fixing the syringe (41) inserted into the syringe holder portion (2)
  • a cylinder handle groove 5 is formed at the distal end of which the cylinder handle 43 of the syringe 41 is coupled, and a male screw coupled to the female screw screw 4 formed at the inner circumferential side of the space portion 3 at the rear end outer circumferential surface thereof.
  • the plunger handle groove 11 to which the plunger handle 45 of the syringe 41 is coupled is formed, and together with the plunger handle detection sensor 12 in the space portion 10 provided inside the operating port 7. It is installed, and the discharge operation port 13 connected to the second motor 14 installed in the space portion 10 through the inner and outer screw gears (16) (17);
  • 2 switch 21 comprises a.
  • the first switch 20 drives the first motor 8 and the second motor 14 at the same time, so that a negative pressure is generated inside the syringe cylinder 42, and the syringe 41 of the syringe 41.
  • the forward and backward rotation and the left and right rotations are repeated, and the second switch 21 drives the second motor 14 to perform a discharge function.
  • the cylinder handle groove 5 and the plunger handle groove 11 are both formed in the inlet wider than the width of the cylinder handle 43 and the plunger handle 45, the cylinder handle 43 and the plunger handle 45 ) So that it can be easily mounted.
  • the syringe cylinder 42 to which the needle 40 is coupled is mounted on the syringe holder 2 formed in the aspirator main body 1.
  • the cylinder handle 43 is coupled to the cylinder handle groove 5 formed in the operating port 7 and the plunger handle 45 is coupled to the plunger handle groove 11 of the discharge operation port 13.
  • the hub 46 portion of the syringe cylinder 42 is exposed from the aspirator body 1 so that the suction state of the cells can be seen.
  • the plunger handle detecting sensor 12 installed in the plunger handle groove 11 detects the mounting of the syringe 41 and sends a signal to the controller 15.
  • the controller 15 operates the second motor 14 to cause the plunger 44 to be slightly retracted by the internal and external screw gears 16 and 17.
  • a space of about 1 ms is created in the syringe cylinder 42. This preparation process is very difficult to push out if there is no space secured in advance when the amount of aspirated cells is too small, so that even a small amount of sample can be easily pushed out using the space secured in advance.
  • the syringe 41 is suction-extracted from the cells of the body in the state mounted on the aspirator main body (1). That is, after the syringe 41 is mounted on the aspirator main body 1, the plunger 44 moves backward to suck and extract the cells of the body in a state where a space of about 1 mm is secured inside the syringe cylinder 42. .
  • the plunger handle 45 is moved backward by the second motor 14 so that a negative pressure is applied to the inside of the syringe cylinder 42.
  • the operating tool 7 holding the cylinder handle 43 is moved by the first motor 8. That is, as the first motor 8 repeats the forward rotation and the reverse rotation, the operating port 7 also repeats the forward rotation and the reverse rotation and moves forward and backward by engaging the male and female screws 4 and 6. Will be repeated.
  • the needle 40 repeats the action of stabbing and spinning while rotating the tissue of the body, so that the cells in the tissue can be suctioned and reliably and reliably extracted.
  • the controller 15 controls the first motor 8 and the second motor 14 to continuously perform the operation until the first switch 20 is pressed once again.
  • the aspirating operation is stopped by pressing the first switch 20, and then the needle 40 is removed from the body, and then the aspirated and extracted cells are pressed by pressing the second switch 21. Discharge by amount.
  • the second motor 14 When the second switch 21 is pressed, the second motor 14 is operated to slightly advance the plunger 44 to discharge the cells sucked into the syringe cylinder 42. In this case, since the controller 15 controls to discharge only the proper amount every time the second switch 21 is pressed, when the amount of suction is large, the second switch 21 is sucked by pressing the second switch 21 several times. Divide out the cells several times.
  • the suction was started in the initial state with a free space of about 1 mm in the syringe cylinder 42, the aspirated cells can be discharged cleanly without leaving even a small amount of aspirated cells.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • External Artificial Organs (AREA)

Abstract

The present invention relates to an automatic cell-sucking device using a thin needle, which can automatically suck cells in a uniform and reliable manner regardless of the personal skill of an operator during processes of sucking and extracting cells from tissue, and which can accurately discharge the required amount of the sucked and extracted cells. The automatic cell sucking device that uses a thin needle comprises: a sucker body (1) having a syringe holder portion (2) for holding a syringe cylinder (42), a space (3) connected to the syringe holder portion (2), and a sucker cap (30); an operating element (7) which has a cylinder handle groove (5) for coupling with a cylinder handle (43), and the outer surface of which has a male screw (6) to be fastened into a female thread (4) formed at an inner surface thereof, and which rotates and moves in the forward and backward directions by means of a first motor (8); a discharge operating element (13) which has a plunger handle groove (11) for coupling with a plunger handle (45) of the syringe, and which is installed together with a plunger handle sensor (12) in a space (10) formed in the operating element (7), and which is connected to a second motor (14) via screw gears (16, 17); a controller (15) for controlling operation of the first motor (8) and the second motor (14); and a first switch (20) and a second switch (21) for operating the first motor (8) and the second motor (14). The automatic cell-sucking device using a thin needle, according to the present invention, can automatically perform a series of sucking operations, thus sucking and extracting cells in a uniform and reliable manner regardless of the personal skill of the operator, and accurately discharging the required amount of the sucked and extracted cells, leading to enhanced reliability for cytoscopy. The automatic cell-sucking device of the present invention improves reliability for the overall process including cell suction and extraction, discharge, and cytoscopy.

Description

자동세침세포흡인기Automatic fine needle cell aspirator
본 발명은 자동세침세포흡인기에 관한 것으로서, 더욱 상세하게는 주사기 본체에 결합된 주사바늘로 신체의 조직을 찔러 세포를 흡인 추출하는 일련의 과정에서 시술자의 개인 숙련 정도와는 무관하게 일률적이고 신뢰성 있게 세포를 자동으로 흡인 추출할 수 있고, 또 흡인 추출된 세포를 필요한 양만큼 정확하게 배출시킬수 있도록 구성된 자동세침세포흡인기에 관한 것이다.The present invention relates to an automatic fine needle cell aspirator, and more particularly, uniformly and reliably regardless of the individual's skill of the operator in a series of processes of aspirating and extracting cells by puncturing tissue of the body with a needle coupled to a syringe body. The present invention relates to an automatic fine needle cell aspirator configured to be able to automatically suction extract cells and to accurately discharge the extracted cells by a required amount.
주지하는 바와 같이 세포검사를 하기 위한 수단의 하나로 주사기가 사용되는데, 이 경우 주사기 본체에 결합된 주사바늘로 신체의 조직을 찔러서 세포를 흡인 추출하여 슬라이드글래스 위에 도말하여 세포검사를 한다. As is well known, a syringe is used as a means for performing a cell test. In this case, a needle is attached to the body of the body with a needle coupled to the syringe body, and the cells are sucked and extracted and smeared on a slide glass to perform a cell test.
상기한 종래의 세포검사를 위하여 세포를 흡인 추출하는 일련의 과정을 살펴보면 다음과 같다.Looking at a series of processes for aspirating the cells for the conventional cytology described above are as follows.
먼저, 주사기 본체에 결합된 주사바늘로 신체의 조직을 찔러 세포를 흡인 추출하는데, 세포를 흡인 추출하기 위한 예비 작업으로 주사기 본체에 결합된 주사바늘을 이용하여 신체의 조직을 찌르면서 돌리고 빼내는 동작을 수회 반복해서 세포를 흡인 추출하기에 용이한 상태로 만들게 된다. 이 상태에서 주사기를 구성하는 플런저를 후진시켜줌으로써 주사기 실린더 내부에 음압을 발생시켜 세포를 흡인 추출하고 있는 것이다.First, the cells are sucked and extracted by puncturing the tissue of the body with a needle coupled to the syringe body. The preliminary work for sucking and extracting the cells is performed by using a needle coupled to the syringe body to poke and rotate the body tissue. Repeat this several times to make the cells easier to aspirate. In this state, the plunger constituting the syringe is retracted to generate negative pressure inside the syringe cylinder, and the cells are sucked out.
그런데, 상기와 같이 세포를 흡인 추출하는 경우에는 시술자의 숙련 정도에 따라 주사바늘로 신체의 세포를 찌르고 빼내는 동작모습이나 강도가 달라지고, 또 반복하는 횟수도 다르기 때문에, 검사할 때마다 세포의 흡인 정도가 달라지게 된다. 따라서, 확실하고 신뢰성 있게 세포를 흡인 추출할 수 없는 단점이 있다.However, in the case of aspirating and extracting the cells as described above, the operation pattern and intensity of puncturing and extracting the cells of the body with the needle vary according to the skill of the operator, and the number of repetitions is different. The degree will vary. Therefore, there is a disadvantage in that the cells can not be sucked and reliably extracted reliably.
한편, 세포검사(세포도말검사)를 하기 위해서는 주사기에 흡인 추출된 세포를 배출키기 위하여 주사기 실린더에 장입된 플런저를 밀어주게 된다. 이때, 손의 감각이나 습관에 의해서 배출량이 결정되기 때문에, 검사할 때마다 그 배출량이 달라져 일정하지 않게 되는 등, 세침 세포검사를 위해서 세포를 흡인 추출 및 배출하는 데 많은 어려움이 있었다.On the other hand, in order to perform a cytology (cytoscopy), the plunger loaded in the syringe cylinder is pushed to discharge the cells extracted by the suction. At this time, since the discharge is determined by the senses and habits of the hand, the discharge varies with each test, such that the discharge becomes inconsistent.
따라서 세포검사에 대한 신뢰도가 떨어질 수밖에 없어 일관된 진단을 하기 어려울 뿐만 아니라, 때에 따라서는 환자를 한 번 더 방문하게 하여 반복 검사를 해야 하는 경우가 빈번한 실정이다.Therefore, it is difficult to make a consistent diagnosis because the reliability of the cell test is inevitably reduced, and in some cases, the patient is repeatedly visited by visiting the patient once more.
상기한 문제점을 해결하기 위한 본 발명의 자동세침세포흡인기는, 주사기를 흡인기 본체에 결합시켜 주사바늘을 이용하여 신체의 조직을 찌르면서 돌리고 빼내는 동작을 수회 반복하는 일련의 과정이 흡인기에 의해 자동으로 이루어지도록 함으로써 시술자의 개인 숙련도와는 무관하게 신뢰성 있게 세포를 흡인 추출할 수 있도록 하는 자동세침세포흡인기를 제공함에 그 목적이 있다.The automatic fine needle cell aspirator of the present invention for solving the above problems is a series of processes in which the needle is coupled to the aspirator main body, and the needle and the needle are rotated and pulled out several times by using the needle. The purpose of the present invention is to provide an automatic fine needle cell aspirator that can reliably suck and extract cells irrespective of the individual skill of the operator.
또, 주사기를 구성하는 플런저를 후진시켜 발생한 음압을 이용하여 세포를 흡인 추출하고 필요한 양만큼 배출하는 과정을 자동으로 수행하도록 함으로써, 세포를 배출하는데 있어서도 신뢰성을 향상시킬 수 있는 자동세침세포흡인기를 제공함에 그 목적이 있다.In addition, by using the negative pressure generated by reversing the plunger constituting the syringe to automatically perform the process of aspirating and extracting the cells by the required amount, providing an automatic fine needle cell aspirator that can improve the reliability in the discharge of cells Has its purpose.
상기한 기술적 과제를 달성하기 위한 본 발명에 의한 자동세침세포흡인기는, 주사기의 허브를 통해 세포가 흡인되는 것을 확인할 수 있도록 본체로부터 상기 허브가 노출된 상태로 주사기가 취부되는 주사기 홀더부 및 이에 연결되는 공간부가 형성되고, 상기 주사기 홀더부에 삽입된 주사기를 고정하는 흡인기 캡이 구비된 흡인기 본체와; 선단부에 상기 주사기의 실린더손잡이가 결합되는 실린더손잡이홈이 형성되고 후단부 외주면에는 상기 공간부 내주면 후방측에 형성된 암나사식스크류에 결합되는 수나사식스크류가 형성되어 상기 공간부 후방에 설치된 제1모터에 의해 회전됨과 아울러 상기 공간부 내부에서 전후 이동되는 작동구와; 상기 주사기의 플런저손잡이가 결합되는 플런저손잡이홈이 형성되고, 플런저손잡이감지센서와 함께 상기 작동구의 내부에 구비된 공간부에 설치되며, 상기 공간부에 설치된 제2모터에 내외 스크류기어를 통해 연결된 배출작동구와; 상기 제1모터와 제2모터의 작동을 제어하는 콘트롤러 및 상기 제1모터와 제2모터를 작동시키는 제1스위치 및 제2스위치;를 포함하는 것을 특징으로 한다.Automatic needle cell aspirator according to the present invention for achieving the above technical problem, the syringe holder portion to which the syringe is mounted in a state in which the hub is exposed from the body so that the cells are aspirated through the hub of the syringe and connected thereto A suction unit body having a suction unit cap for fixing a syringe inserted into the syringe holder unit; A cylinder handle groove is formed at the front end to engage the cylinder handle of the syringe. A rear screw is formed at the outer end of the rear end to form a male screw coupled to a female screw formed at a rear side of the inner circumferential surface of the syringe. An operating tool which is rotated and moved back and forth within the space part; A plunger handle groove is formed to which the plunger handle of the syringe is coupled, and is installed in a space provided inside the operating port together with a plunger handle detection sensor, and is discharged through an internal and external screw gear to a second motor installed in the space. An operating tool; And a controller for controlling the operation of the first motor and the second motor, and a first switch and a second switch for operating the first motor and the second motor.
이상과 같이 구성된 본 발명의 자동세침세포흡인기에 의하면, 흡인기 본체에 결합된 주사기의 주사바늘을 이용하여 신체의 조직을 찌르면서 돌리고 빼내는 일련의 흡인동작이 흡인기에 의해 자동으로 이루어지므로, 시술자의 개인 숙련정도와는 무관하게 일률적이고, 신뢰성 있게 세포를 흡인 추출할 수 있는 효과가 있다.According to the automatic fine needle cell aspirator of the present invention configured as described above, since a series of suction operations are performed automatically by the aspirator, using a needle of a syringe coupled to the aspirator body, the needle is turned and pulled out. Irrespective of the level of skill, there is an effect of uniformly and reliably aspirating cells.
또, 본 발명의 자동세침세포흡인기에 의하면, 세포를 주사기 실린더에 흡인 추출한 후 세포검사를 위해서 세포를 배출시키는 경우에도, 필요한 양만큼 정확하고 확실하게 배출시킬 수 있으므로, 세포검사의 신뢰도를 높일 수 있는 등 세포의 흡인 추출 및 배출, 그리고 세포검사에 따른 전반적인 사항에 대한 신뢰도를 높이는 효과가 있다.In addition, according to the automatic fine needle cell aspirator of the present invention, even when the cells are aspirated and extracted by a syringe cylinder, the cells can be discharged accurately and reliably in a necessary amount, thereby increasing the reliability of the cytology. It is effective in increasing the reliability of the aspiration extraction and discharge of cells, and the overall results of cytology.
도1은 본 발명에 의한 자동세침세포흡인기의 전체 구성을 보인 사시도Figure 1 is a perspective view showing the overall configuration of the automatic fine needle cell aspirator according to the present invention
도2는 본 발명에 의한 자동세침세포흡인기의 내부구성을 보인 사시도Figure 2 is a perspective view showing the internal configuration of the automatic fine needle cell aspirator according to the present invention
도3은 본 발명에 의한 자동세침세포흡인기의 내부구성을 보인 단면도Figure 3 is a cross-sectional view showing the internal configuration of the automatic fine needle cell aspirator according to the present invention
도4은 본 발명에 의한 자동세침세포흡인기의 내부구성을 분해한 단면도Figure 4 is an exploded cross-sectional view of the internal structure of the automatic fine needle cell aspirator according to the present invention
*** 도면의 주요부분에 대한 부호의 설명 ****** Explanation of symbols for main parts of drawing ***
1: 흡인기 본체 2: 주사기 홀더부1: aspirator main body 2: syringe holder
3: 공간부 4: 암나사식스크류3: space part 4: female screw
5: 실린더손잡이홈 6: 수나사식스크류5: cylinder handle groove 6: male threaded screw
7: 작동구 8: 제1모터7: Actuator 8: First Motor
10: 공간부 11: 플런저손잡이홈10: space part 11: plunger handle groove
12: 플런저손잡이감지센서 13: 배출작동구12: Plunger handle detection sensor 13: discharge operation port
14: 제2모터 15: 콘트롤러14: second motor 15: controller
16, 17: 내외 스크류기어 20: 제1스위치16 and 17: internal and external screw gear 20: first switch
21: 제2스위치 30: 흡인기 캡21: second switch 30: aspirator cap
40: 주사바늘 41: 주사기40: needle 41: syringe
42: 주사기 실린더 43: 실린더손잡이42: syringe cylinder 43: cylinder handle
44: 플런저 45: 플런저손잡이44: plunger 45: plunger handle
46: 허브46: hub
본 발명에 따른 자동세침세포흡인기에 관한 구성의 예를 이하 부수되는 도면과 관련하여 상세하게 설명하면 다음과 같다. An example of a configuration related to an automatic fine needle cell aspirator according to the present invention will be described below in detail with reference to the accompanying drawings.
도1은 본 발명에 의한 자동세침세포흡인기의 전체 구성을 보인 사시도, 도2는 본 발명에 의한 자동세침세포흡인기의 내부구성을 보인 사시도, 도3은 본 발명에 의한 자동세침세포흡인기의 내부구성을 보인 단면도, 도4는 본 발명에 의한 자동세침세포흡인기의 내부구성을 분해한 단면도이다.1 is a perspective view showing the overall configuration of the automatic fine needle cell aspirator according to the present invention, Figure 2 is a perspective view showing the internal structure of an automatic fine needle cell aspirator according to the present invention, Figure 3 is an internal configuration of an automatic fine needle cell aspirator according to the present invention 4 is a cross-sectional view showing the internal structure of the automatic fine cell aspirator according to the present invention.
본 발명에 의한 자동세침세포흡인기는, 주사바늘(40)이 연결된 주사기(41)의 허브(46)를 통해 세포가 흡인되는 것을 확인할 수 있도록 본체로부터 상기 허브(46)가 노출된 상태로 주사기(41)가 취부되는 주사기 홀더부(2) 및 이에 연결되는 공간부(3)가 형성되고, 상기 주사기 홀더부(2)에 삽입된 주사기(41)를 고정하는 흡인기 캡(30)이 구비된 흡인기 본체(1)와; 선단부에 상기 주사기(41)의 실린더손잡이(43)가 결합되는 실린더손잡이홈(5)이 형성되고 후단부 외주면에는 상기 공간부(3) 내주면 후방측에 형성된 암나사식스크류(4)에 결합되는 수나사식스크류(6)가 형성되어 상기 공간부(3) 후방에 설치된 제1모터(8)에 의해 회전됨과 아울러 상기 공간부(3) 내부에서 전후 이동되는 작동구(7)와; 상기 주사기(41)의 플런저손잡이(45)가 결합되는 플런저손잡이홈(11)이 형성되고, 플런저손잡이감지센서(12)와 함께 상기 작동구(7)의 내부에 구비된 공간부(10)에 설치되며, 상기 공간부(10)에 설치된 제2모터(14)에 내외 스크류기어(16)(17)를 통해 연결된 배출작동구(13)와; 상기 제1모터(8)와 제2모터(14)의 작동을 제어하는 콘트롤러(15) 및 상기 제1모터(8)와 제2모터(14)를 각각 작동시키는 제1스위치(20) 및 제2스위치(21);를 포함하여 이루어진다.The automatic fine needle cell aspirator according to the present invention includes a syringe (with the hub 46 exposed from the main body) to confirm that the cells are sucked through the hub 46 of the syringe 41 to which the needle 40 is connected. A syringe holder portion (2) on which 41 is mounted and a space portion (3) connected thereto are formed, and an aspirator provided with an aspirator cap (30) for fixing the syringe (41) inserted into the syringe holder portion (2) A main body 1; A cylinder handle groove 5 is formed at the distal end of which the cylinder handle 43 of the syringe 41 is coupled, and a male screw coupled to the female screw screw 4 formed at the inner circumferential side of the space portion 3 at the rear end outer circumferential surface thereof. An actuating mechanism (7) formed with six screws (6), which is rotated by the first motor (8) installed at the rear of the space portion (3) and moved back and forth within the space portion (3); The plunger handle groove 11 to which the plunger handle 45 of the syringe 41 is coupled is formed, and together with the plunger handle detection sensor 12 in the space portion 10 provided inside the operating port 7. It is installed, and the discharge operation port 13 connected to the second motor 14 installed in the space portion 10 through the inner and outer screw gears (16) (17); A controller 15 for controlling the operation of the first motor 8 and the second motor 14 and a first switch 20 and a first for operating the first motor 8 and the second motor 14, respectively. 2 switch 21; comprises a.
여기서, 상기 제1스위치(20)는 상기 제1모터(8)와 제2모터(14)를 동시에 구동하여, 상기 주사기 실린더(42) 내부에 음압이 발생하게 함과 아울러 상기 주사기(41)의 전후진과 좌우회전이 반복되도록 하고, 상기 제2스위치(21)는 상기 제2모터(14)를 구동하여 배출기능을 담당한다.Here, the first switch 20 drives the first motor 8 and the second motor 14 at the same time, so that a negative pressure is generated inside the syringe cylinder 42, and the syringe 41 of the syringe 41. The forward and backward rotation and the left and right rotations are repeated, and the second switch 21 drives the second motor 14 to perform a discharge function.
또, 상기 실린더손잡이홈(5)과 플런저손잡이홈(11)은 모두 입구가 상기 실린더손잡이(43) 및 플런저손잡이(45)의 폭보다 넓게 형성되어, 상기 실린더손잡이(43)와 플런저손잡이(45)를 손쉽게 장착할 수 있도록 한다.In addition, the cylinder handle groove 5 and the plunger handle groove 11 are both formed in the inlet wider than the width of the cylinder handle 43 and the plunger handle 45, the cylinder handle 43 and the plunger handle 45 ) So that it can be easily mounted.
이상과 같이 구성된 본 발명의 자동세침세포흡인기에 관한 작용을 상세하게 설명하면 다음과 같다.Referring to the action of the automatic fine needle cell aspirator of the present invention configured as described above in detail.
본 발명에 의한 자동세침세포흡인기를 사용하여 세포를 흡인 추출하려면, 흡인기 캡(30)을 열고 주사기(41)를 흡인기 본체(1)의 내부에 설치하고 흡인기 캡(30)을 닫음으로써, 상기 주사기(41)를 흡인기에 장착한다.To aspirate and extract cells using the automatic fine needle cell aspirator according to the present invention, by opening the aspirator cap 30 and installing the syringe 41 inside the aspirator body 1 and closing the aspirator cap 30, Attach (41) to the aspirator.
구체적으로 주사바늘(40)이 결합된 주사기 실린더(42)를 흡인기 본체(1)에 형성된 주사기 홀더부(2)에 장착한다. 이때 실린더 손잡이(43)를 작동구(7)에 형성된 실린더손잡이홈(5)에 결합시키고, 또 플런저손잡이(45)를 배출작동구(13)의 플런저손잡이홈(11)에 결합시킨다. 다만, 상기 주사기 실린더(42)의 허브(46) 부분은 상기 흡인기 본체(1)로부터 노출되도록 하여 세포의 흡인 상태를 볼 수 있도록 한다.Specifically, the syringe cylinder 42 to which the needle 40 is coupled is mounted on the syringe holder 2 formed in the aspirator main body 1. At this time, the cylinder handle 43 is coupled to the cylinder handle groove 5 formed in the operating port 7 and the plunger handle 45 is coupled to the plunger handle groove 11 of the discharge operation port 13. However, the hub 46 portion of the syringe cylinder 42 is exposed from the aspirator body 1 so that the suction state of the cells can be seen.
상기 주사기(41)의 장착이 완료되면, 상기 플런저손잡이홈(11)에 설치된 플런저손잡이 감지센서(12)가 주사기(41)의 장착을 감지하여 콘트롤러(15)에 신호를 보내게 되고, 이 신호에 따라 상기 콘트롤러(15)가 제2모터(14)를 작동시킴으로써 내외 스크류기어(16)(17)에 의해 상기 플런저(44)가 약간 후진하도록 한다. 이에 따라 상기 주사기 실린더(42) 내부에 대략 1㏄ 정도의 공간이 생기게 된다. 이 준비과정은, 흡인된 세포의 양이 너무 적을 경우에는 미리 확보된 공간이 없으면 밀어내기가 매우 어려우므로, 이렇게 미리 확보한 공간을 이용하여 미량의 검체라도 손쉽게 밀어내도록 하기 위한 것이다.When the mounting of the syringe 41 is completed, the plunger handle detecting sensor 12 installed in the plunger handle groove 11 detects the mounting of the syringe 41 and sends a signal to the controller 15. As a result, the controller 15 operates the second motor 14 to cause the plunger 44 to be slightly retracted by the internal and external screw gears 16 and 17. As a result, a space of about 1 ms is created in the syringe cylinder 42. This preparation process is very difficult to push out if there is no space secured in advance when the amount of aspirated cells is too small, so that even a small amount of sample can be easily pushed out using the space secured in advance.
상기와 같이 주사기(41)가 흡인기 본체(1)에 장착된 상태에서 신체의 세포를 흡인 추출한다. 즉, 상기 흡인기 본체(1)에 주사기(41)가 장착된 후 플런저(44)가 후진하여 상기 주사기 실린더(42) 내부에 1㏄ 정도의 공간이 확보된 상태에서 신체의 세포를 흡인 추출하는 것이다.As described above, the syringe 41 is suction-extracted from the cells of the body in the state mounted on the aspirator main body (1). That is, after the syringe 41 is mounted on the aspirator main body 1, the plunger 44 moves backward to suck and extract the cells of the body in a state where a space of about 1 mm is secured inside the syringe cylinder 42. .
구체적으로 신체의 조직 내에 주사바늘(40)을 찌른 다음 제1스위치(20)를 누르면, 상기 제2모터(14)에 의해 플런저손잡이(45)가 후진하여 상기 주사기 실린더(42) 내부에 음압이 걸리게 되고, 이와 동시에 제1모터(8)에 의해 실린더손잡이(43)를 잡고 있는 작동구(7)가 움직이게 된다. 즉, 상기 제1모터(8)가 정회전과 역회전을 반복함에 따라 상기 작동구(7) 역시 정회전과 역회전을 반복함과 아울러 암수스크류(4)(6)의 맞물림에 의해 전후진을 반복하게 된다.Specifically, when the needle 40 is inserted into the tissue of the body and the first switch 20 is pressed, the plunger handle 45 is moved backward by the second motor 14 so that a negative pressure is applied to the inside of the syringe cylinder 42. At the same time, the operating tool 7 holding the cylinder handle 43 is moved by the first motor 8. That is, as the first motor 8 repeats the forward rotation and the reverse rotation, the operating port 7 also repeats the forward rotation and the reverse rotation and moves forward and backward by engaging the male and female screws 4 and 6. Will be repeated.
결국, 상기 주사기 실린더(42)에 음압이 걸린 상태에서 주사바늘(40)이 신체의 조직을 돌면서 찌르고 돌면서 빠지는 작용을 반복하게 되어, 조직 내의 세포를 확실하고 신뢰성 있게 흡인 추출할 수 있게 된다. 이때, 콘트롤러(15)는 상기 제1스위치(20)를 한 번 누르면 다시 누를 때까지 상기 동작을 지속적으로 수행하도록 상기 제1모터(8)와 제2모터(14)를 제어한다..As a result, in the state in which the negative pressure is applied to the syringe cylinder 42, the needle 40 repeats the action of stabbing and spinning while rotating the tissue of the body, so that the cells in the tissue can be suctioned and reliably and reliably extracted. At this time, the controller 15 controls the first motor 8 and the second motor 14 to continuously perform the operation until the first switch 20 is pressed once again.
상기와 같이 세포를 흡인 추출하고 나면, 상기 제1스위치(20)를 눌러 흡인동작을 멈추게 한 뒤 주사바늘(40)을 신체로부터 빼낸 다음, 제2스위치(21)를 눌러 흡인 추출된 세포를 필요한 양만큼 배출시킨다.After aspirating and extracting the cells as described above, the aspirating operation is stopped by pressing the first switch 20, and then the needle 40 is removed from the body, and then the aspirated and extracted cells are pressed by pressing the second switch 21. Discharge by amount.
상기 제2스위치(21)를 누르면, 상기 제2모터(14)가 작동하여 상기 플런저(44)를 약간 전진시켜 상기 주사기 실린더(42)에 흡인된 세포를 배출시켜주게 된다. 여기서 상기 제2스위치(21)를 한 번 누를 때마다 적정 양만큼만 배출되도록 상기 콘트롤러(15)가 제어하므로, 흡인된 양이 많을 경우에는 상기 제2스위치(21)를 여러 번을 누름으로써 흡인된 세포를 몇 번으로 나누어 배출시킨다.When the second switch 21 is pressed, the second motor 14 is operated to slightly advance the plunger 44 to discharge the cells sucked into the syringe cylinder 42. In this case, since the controller 15 controls to discharge only the proper amount every time the second switch 21 is pressed, when the amount of suction is large, the second switch 21 is sucked by pressing the second switch 21 several times. Divide out the cells several times.
또, 초기 상태에서 상기 주사기 실린더(42)에 약 1㏄ 정도의 여유 공간이 확보된 상태로 흡인을 시작하였으므로, 흡인된 세포의 양이 미량이더라도 남기지 않고 깨끗하게 배출시킬 수 있게 된다. In addition, since the suction was started in the initial state with a free space of about 1 mm in the syringe cylinder 42, the aspirated cells can be discharged cleanly without leaving even a small amount of aspirated cells.

Claims (4)

  1. 주사기(41)의 허브(46)를 통해 세포가 흡인되는 것을 확인할 수 있도록 본체로부터 상기 허브(46)가 노출된 상태로 주사기(41)가 취부되는 주사기 홀더부(2) 및 이에 연결되는 공간부(3)가 형성되고, 상기 주사기 홀더부(2)에 삽입된 주사기(41)를 고정하는 흡인기 캡(30)이 구비된 흡인기 본체(1)와;In order to confirm that the cells are sucked through the hub 46 of the syringe 41, the syringe holder 2 to which the syringe 41 is mounted with the hub 46 exposed from the main body and the space connected thereto An aspirator main body (1) formed with an aspirator cap (30) for fixing a syringe (41) inserted into the syringe holder portion (2);
    선단부에 상기 주사기(41)의 실린더손잡이(43)가 결합되는 실린더손잡이홈(5)이 형성되고 후단부 외주면에는 상기 공간부(3) 내주면 후방측에 형성된 암나사식스크류(4)에 결합되는 수나사식스크류(6)가 형성되어 상기 공간부(3) 후방에 설치된 제1모터(8)에 의해 회전됨과 아울러 상기 공간부(3) 내부에서 전후 이동되는 작동구(7)와;A cylinder handle groove 5 is formed at the distal end of which the cylinder handle 43 of the syringe 41 is coupled, and a male screw coupled to the female screw screw 4 formed at the inner circumferential side of the space portion 3 at the rear end outer circumferential surface thereof. An actuating mechanism (7) formed with six screws (6), which is rotated by the first motor (8) installed at the rear of the space portion (3) and moved back and forth within the space portion (3);
    상기 주사기(41)의 플런저손잡이(45)가 결합되는 플런저손잡이홈(11)이 형성되고, 플런저손잡이감지센서(12)와 함께 상기 작동구(7)의 내부에 구비된 공간부(10)에 설치되며, 상기 공간부(10)에 설치된 제2모터(14)에 내외 스크류기어(16)(17)를 통해 연결된 배출작동구(13)와;The plunger handle groove 11 to which the plunger handle 45 of the syringe 41 is coupled is formed, and together with the plunger handle detection sensor 12 in the space portion 10 provided inside the operating port 7. It is installed, and the discharge operation port 13 connected to the second motor 14 installed in the space portion 10 through the inner and outer screw gears (16) (17);
    상기 제1모터(8)와 제2모터(14)의 작동을 제어하는 콘트롤러(15) 및 상기 제1모터(8)와 제2모터(14)를 작동시키는 제1스위치(20) 및 제2스위치(21);를 포함하는 것을 특징으로 하는 자동세침세포흡인기. A controller 15 for controlling the operation of the first motor 8 and the second motor 14 and a first switch 20 and a second for operating the first motor 8 and the second motor 14. Automatic fine needle cell aspirator comprising a switch (21).
  2. 제1항에 있어서,The method of claim 1,
    상기 실린더손잡이(43)와 플런저손잡이(45)가 각각 안전하게 장착되도록 상기 실린더홈(5) 및 플런저손잡이홈(11)이 각각 라운드로 구성된 것을 특징으로 하는 자동세침세포흡인기.Automatic cylinder needle aspirator, characterized in that the cylinder groove (43) and the plunger handle (45) is mounted in a round, so that the cylinder groove (5) and the plunger handle groove (11), respectively.
  3. 제1항 또는 제2항에 있어서,The method according to claim 1 or 2,
    상기 콘트롤러(15)는, 상기 주사기(41)의 최초 장착시에는 상기 제2모터(14)를 제어하여 상기 주사기 실린더(42)의 내부에 1㏄ 정도의 여유공간이 확보되도록 상기 주사기(41)의 플런저(44)가 결합된 배출작동구(13)를 후진시키고, The controller 15 controls the second motor 14 when the syringe 41 is first mounted so that a space of about 1 mm is secured in the syringe cylinder 42. Retracts the discharge operation opening 13 to which the plunger 44 of the
    상기 제1스위치(20)를 누르면 상기 제2모터(14)에 의해 상기 주사기 실린더(42) 내부에 음압이 발생됨과 동시에 상기 제1모터(8)에 의해 상기 작동구(7)가 전후진 및 정역회전을 반복하는 흡인작동이 이루어지도록, 상기 제1모터(8)와 제2모터(14)를 제어하는 것을 특징으로 하는 자동세침흡인기.When the first switch 20 is pressed, a negative pressure is generated inside the syringe cylinder 42 by the second motor 14, and at the same time, the operating hole 7 is moved forward and backward by the first motor 8. An automatic fine needle aspirator, characterized in that the first motor (8) and the second motor (14) are controlled to perform a suction operation to repeat the forward and reverse rotation.
  4. 제3항에 있어서,The method of claim 3,
    상기 컨트롤러(15)는 상기 제1스위치(20)를 한 번 누르면 다시 누를 때까지 상기 흡인작동을 계속하고, 상기 제2스위치(21)를 한 번 누르면 상기 주사기 실린더(42) 내부로 흡인된 세포가 일정량만큼만 배출되는 배출작동이 이루어지도록, 상기 제1모터(8) 및 제2모터(14)를 제어하는 것을 특징으로 하는 자동세침흡인기.The controller 15 continues the suction operation until the first switch 20 is pressed once and the second switch 21 is pressed, and the cells sucked into the syringe cylinder 42 are pressed once. Automatic fine suction device, characterized in that to control the first motor (8) and the second motor 14 so that the discharge operation is discharged only a predetermined amount.
PCT/KR2010/000968 2009-02-24 2010-02-17 Automatic cell-sucking device using a thin needle WO2010098549A2 (en)

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CN111643201A (en) * 2020-07-02 2020-09-11 西安交通大学口腔医院 Clamping device for oral tooth implantation

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