WO2010094413A8 - Zerstäuber - Google Patents

Zerstäuber Download PDF

Info

Publication number
WO2010094413A8
WO2010094413A8 PCT/EP2010/000796 EP2010000796W WO2010094413A8 WO 2010094413 A8 WO2010094413 A8 WO 2010094413A8 EP 2010000796 W EP2010000796 W EP 2010000796W WO 2010094413 A8 WO2010094413 A8 WO 2010094413A8
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical preparation
atomizer
atomizing
cloth
sealed
Prior art date
Application number
PCT/EP2010/000796
Other languages
English (en)
French (fr)
Other versions
WO2010094413A3 (de
WO2010094413A2 (de
Inventor
Lothar Kiesewetter
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Priority to JP2011549477A priority Critical patent/JP2012517831A/ja
Priority to EP10709956A priority patent/EP2398538A2/de
Priority to CA2752677A priority patent/CA2752677A1/en
Priority to US13/201,744 priority patent/US20120132199A1/en
Publication of WO2010094413A2 publication Critical patent/WO2010094413A2/de
Publication of WO2010094413A3 publication Critical patent/WO2010094413A3/de
Publication of WO2010094413A8 publication Critical patent/WO2010094413A8/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/02—Membranes or pistons acting on the contents inside the container, e.g. follower pistons
    • B05B11/026—Membranes separating the content remaining in the container from the atmospheric air to compensate underpressure inside the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1001—Piston pumps
    • B05B11/1015—Piston pumps actuated without substantial movement of the nozzle in the direction of the pressure stroke
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1028—Pumps having a pumping chamber with a deformable wall
    • B05B11/1032—Pumps having a pumping chamber with a deformable wall actuated without substantial movement of the nozzle in the direction of the pressure stroke
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042—Components or details
    • B05B11/1052—Actuation means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042—Components or details
    • B05B11/1073—Springs
    • B05B11/1074—Springs located outside pump chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8218—Gas operated
    • A61M2205/8225—Gas operated using incorporated gas cartridges for the driving gas
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0038—Inner container disposed in an outer shell or outer casing

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Mechanical Engineering (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Nozzles (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

Es wird ein einfach aufgebauter Zerstäuber (1) zur Zerstäubung einer Arzneimittel Zubereitung (2) zur medizinischen Aerosol-Therapie vorgeschlagen. Die Arzneimittelzubereitung (2) wird restgasfrei in einem lappenartigen Beutel (4) aus zwei ringförmigen Folienstücken (29, 30) aufgenommen. Ein Förderkolben (10) wird pneumatisch angetrieben und durch eine Schlauchdichtung (24) abgedichtet.
PCT/EP2010/000796 2009-02-18 2010-02-10 Zerstäuber WO2010094413A2 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2011549477A JP2012517831A (ja) 2009-02-18 2010-02-10 ネブライザ
EP10709956A EP2398538A2 (de) 2009-02-18 2010-02-10 Zerstäuber
CA2752677A CA2752677A1 (en) 2009-02-18 2010-02-10 Nebuliser
US13/201,744 US20120132199A1 (en) 2009-02-18 2010-02-10 Atomizer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09002253 2009-02-18
EP09002253.4 2009-02-18

Publications (3)

Publication Number Publication Date
WO2010094413A2 WO2010094413A2 (de) 2010-08-26
WO2010094413A3 WO2010094413A3 (de) 2011-01-06
WO2010094413A8 true WO2010094413A8 (de) 2011-06-03

Family

ID=40751024

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2010/000796 WO2010094413A2 (de) 2009-02-18 2010-02-10 Zerstäuber

Country Status (5)

Country Link
US (1) US20120132199A1 (de)
EP (1) EP2398538A2 (de)
JP (1) JP2012517831A (de)
CA (1) CA2752677A1 (de)
WO (1) WO2010094413A2 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2077132A1 (de) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Abgabevorrichtung, Aufbewahrungsvorrichtung und Verfahren zur Abgabe einer Formulierung
US10011906B2 (en) 2009-03-31 2018-07-03 Beohringer Ingelheim International Gmbh Method for coating a surface of a component
EP3508239B1 (de) 2009-05-18 2020-12-23 Boehringer Ingelheim International GmbH Adapter, inhalationseinrichtung und zerstäuber
WO2011064164A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
EP2504051B1 (de) 2009-11-25 2019-09-04 Boehringer Ingelheim International GmbH Zerstäuber
WO2011160932A1 (en) 2010-06-24 2011-12-29 Boehringer Ingelheim International Gmbh Nebulizer
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
FR3002926B1 (fr) * 2013-03-06 2016-02-19 Aptar France Sas Dispositif de distribution de produit fluide.
WO2014138207A1 (en) * 2013-03-07 2014-09-12 Yehuda Ivri Pressure multiplying aerosol pump
US9277770B2 (en) 2013-03-14 2016-03-08 R. J. Reynolds Tobacco Company Atomizer for an aerosol delivery device formed from a continuously extending wire and related input, cartridge, and method
US9918495B2 (en) 2014-02-28 2018-03-20 Rai Strategic Holdings, Inc. Atomizer for an aerosol delivery device and related input, aerosol production assembly, cartridge, and method
EP3030298B1 (de) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Vernebler
EP2835146B1 (de) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Zerstäuber
EA032459B1 (ru) 2014-05-07 2019-05-31 Бёрингер Ингельхайм Интернациональ Гмбх Небулайзер
US10722666B2 (en) 2014-05-07 2020-07-28 Boehringer Ingelheim International Gmbh Nebulizer with axially movable and lockable container and indicator
PL3139979T3 (pl) 2014-05-07 2023-12-27 Boehringer Ingelheim International Gmbh Jednostka, nebulizator i sposób
ES2839279T3 (es) 2014-08-28 2021-07-05 Norton Waterford Ltd Módulo de monitorización de cumplimiento para un inhalador accionado por respiración
GB2536259A (en) * 2015-03-11 2016-09-14 Linde Ag A device for atomising a liquid
RU2700159C2 (ru) * 2015-06-12 2019-09-12 Филип Моррис Продактс С.А. Выдачной механизм
WO2017088064A1 (en) * 2015-11-26 2017-06-01 Goumeniouk Alexander Philip Triggered quantal drug delivery device, method and system ("tqd3")
CN106563196A (zh) * 2016-05-20 2017-04-19 孟庆军 一种儿科医用紧急雾化器
WO2018234525A1 (en) * 2017-06-22 2018-12-27 Softhale Nv MULTI-LIQUID NOZZLE INHALATION DEVICE AND METHOD
DE102018117731A1 (de) * 2018-01-16 2019-07-18 F+K Innovationen Gmbh & Co. Kg Vorrichtung zur Dosierung von Flüssigkeit
BR112021001981A2 (pt) * 2018-08-10 2021-04-27 Softhale Nv dispositivo de inalação de alta pressão
US20210030978A1 (en) * 2019-07-29 2021-02-04 Cai Gu Huang Cartridge with single-layer container and its nozzle-shaped cap for nebulization inhalation
CN111408000A (zh) * 2019-12-12 2020-07-14 上海市肺科医院 一种无痛自动麻醉装置
WO2022200487A1 (en) * 2021-03-25 2022-09-29 Jt International Sa Aerosol generating device with an at least in part non-rigid e-liquid reservoir
CA3237198A1 (en) * 2021-11-05 2023-05-11 Brian William Pierro Compressed gas nebulizer
CN117281984A (zh) * 2021-12-27 2023-12-26 广州阜耀生物科技有限公司 一种抛射型气雾剂给用辅助设备及其使用方法
WO2024086961A1 (en) * 2022-10-24 2024-05-02 The Procter & Gamble Company Pump dispenser

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1314002A (fr) * 1961-11-24 1963-01-04 Procédé et dispositif pour distribuer une substance non compacte
DE2228580A1 (de) * 1972-06-12 1974-01-03 Continental Gummi Werke Ag Rollbalg insbesondere fuer pneumatische oder hydraulische stossdaempfer in fahrzeugfederungen
US4012472A (en) * 1975-07-17 1977-03-15 Arbrook, Inc. Medical fluids container
US4159722A (en) * 1977-03-28 1979-07-03 Sherwood Medical Industries, Inc. Pressure regulator for endotracheal tube cuff or the like
CA1097276A (en) * 1978-12-15 1981-03-10 Marcel J. H. Staar Package for storing and spraying small amounts of liquids
US4603794A (en) * 1985-03-29 1986-08-05 Battelle Development Corporation Pressure multiplying dispenser
US4729764A (en) * 1986-06-05 1988-03-08 Gualtier Quentin E Irrigator and tissue separator
US5129550A (en) * 1989-01-23 1992-07-14 Battelle Memorial Institute Spray bottle apparatus with force multiply pistons
GB9312984D0 (en) * 1993-06-23 1993-08-04 Bespak Plc Atomising dispenser
NL1010749C2 (nl) * 1998-12-07 2000-06-08 V O F Pharmasept Houder voor het gedoseerd en in hoofdzaak kiemvrij afgeven van een vloeistof.
DE19937442A1 (de) * 1999-08-07 2001-02-08 Pfeiffer Erich Gmbh & Co Kg Spender für strömungsfähige Medien, insbesondere zurZerstäubung von Flüssigkeiten
JP4261834B2 (ja) * 2002-07-25 2009-04-30 泉工医科工業株式会社 液体バッグ、液体バッグ用口部材およびその製造方法
DE102005024439A1 (de) 2005-05-24 2006-12-07 Boehringer Ingelheim International Gmbh Zerstäuber

Also Published As

Publication number Publication date
US20120132199A1 (en) 2012-05-31
EP2398538A2 (de) 2011-12-28
JP2012517831A (ja) 2012-08-09
WO2010094413A3 (de) 2011-01-06
WO2010094413A2 (de) 2010-08-26
CA2752677A1 (en) 2010-08-26

Similar Documents

Publication Publication Date Title
WO2010094413A8 (de) Zerstäuber
SV2007002120A (es) Dispositivo inhalador de medicamentos
MD20100077A2 (en) Dosing device for the inhalation of a powdery substance
MX2007012228A (es) Dispositivo para dosificar y para nebulizacion en seco.
MX2012013553A (es) Generador de aerosol.
WO2008094219A3 (en) Pulse drug nebulization system, formulations therefore, and methods of use
IL190838A0 (en) Intranasal administration of rapid acting insulin
WO2008021451A3 (en) Human-powered dry powder inhaler and dry powder inhaler compositions
WO2007123945A3 (en) Mechanical single dose intrapulmonary drug delivery devices
MX2008014892A (es) Ampolla desechable para un dispositivo generador de aerosol.
WO2005102431A3 (en) Aerosol delivery apparatus for pressure assisted breathing
IL179012A (en) A drug containing cetirizine for the treatment of nasal inflammation, a process for its preparation and use
JP2014530231A5 (de)
WO2011008662A9 (en) Powder delivery devices and methods of using the same
MX2014004279A (es) Composiciones que comprenden sulfato de salbutamol.
WO2012052853A3 (en) Oral dosing device for administration of medication
MX349090B (es) Dispositivo separador modular para el tratamiento de infecciones de la prótesis de las extremidades humanas.
AR034906A1 (es) Procedimiento para la union por soldadura por medio del propio material de capsulas de uso medicinal para inhalacion y aparato para efectuar la union por soldadura
WO2005030273A3 (en) High-pressure sterilization to terminally sterilize pharmaceutical preparations and medical products
WO2012054878A3 (en) Delivery systems and method thereof
JP2021509676A (ja) 精密嗅覚装置によるレボドパ粉末の鼻腔内送達
WO2011061498A3 (en) Inhalation solutions
CN202666131U (zh) 药气发生装置
WO2011049540A3 (en) The pharmaceutical composition in dry powder form for inhalation
WO2009149317A3 (en) Transmucosal delivery of therapeutic agents and methods of use thereof

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 10709956

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2010709956

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2011549477

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 2752677

Country of ref document: CA

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 13201744

Country of ref document: US