WO2010036904A3 - Preparation of valganciclovir and its salts - Google Patents

Preparation of valganciclovir and its salts Download PDF

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Publication number
WO2010036904A3
WO2010036904A3 PCT/US2009/058397 US2009058397W WO2010036904A3 WO 2010036904 A3 WO2010036904 A3 WO 2010036904A3 US 2009058397 W US2009058397 W US 2009058397W WO 2010036904 A3 WO2010036904 A3 WO 2010036904A3
Authority
WO
WIPO (PCT)
Prior art keywords
valganciclovir
salts
preparation
processes
intermediates
Prior art date
Application number
PCT/US2009/058397
Other languages
French (fr)
Other versions
WO2010036904A2 (en
Inventor
Pratap Reddy Padi
Vijaya Anand Ramasamy
Babu Ireni
Srihari Babu Karrothu
Madhusudhan Reddy Ganta
Krishna Jonnada
Srinivas Polavarapu
Venkata Madhavi Yaddanapudi
Pranab Haldar
Krishna Vinigari
Narasimha Rao Pagadala
Ravindra Vedantham
Satyanarayana Kisara
Venkata Naga Kali Varaprasada Raju Vetukuri
Sateesh Kamath Suchitra
Sakthivel Shanmugam
Rama Krishna Venkata Medisetti
Kushal Surajmal Manudhane
Original Assignee
Dr. Reddy's Laboratories Ltd.
Dr. Reddy's Laboratories, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr. Reddy's Laboratories Ltd., Dr. Reddy's Laboratories, Inc. filed Critical Dr. Reddy's Laboratories Ltd.
Publication of WO2010036904A2 publication Critical patent/WO2010036904A2/en
Publication of WO2010036904A3 publication Critical patent/WO2010036904A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Abstract

Processes for preparing valganciclovir and pharmaceutically acceptable salts thereof, as well as intermediates for the processes.
PCT/US2009/058397 2008-09-26 2009-09-25 Preparation of valganciclovir and its salts WO2010036904A2 (en)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
IN2375/CHE/2008 2008-09-26
IN2375CH2008 2008-09-26
US12220008P 2008-12-12 2008-12-12
US61/122,200 2008-12-12
IN159/CHE/2009 2009-01-23
IN159CH2009 2009-01-23
IN289/CHE/2009 2009-02-10
IN289CH2009 2009-02-10
US16308909P 2009-03-25 2009-03-25
US61/163,089 2009-03-25
US18502509P 2009-06-08 2009-06-08
US61/185,025 2009-06-08

Publications (2)

Publication Number Publication Date
WO2010036904A2 WO2010036904A2 (en) 2010-04-01
WO2010036904A3 true WO2010036904A3 (en) 2010-07-15

Family

ID=42060399

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/058397 WO2010036904A2 (en) 2008-09-26 2009-09-25 Preparation of valganciclovir and its salts

Country Status (1)

Country Link
WO (1) WO2010036904A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100298564A1 (en) * 2009-05-25 2010-11-25 Venu Nalivela Preparation of amorphous valganciclovir hydrochloride
CN102718765B (en) * 2011-03-31 2015-01-07 四川科伦药物研究有限公司 Method for preparing and purifying Valganciclovir hydrochloride
CN109212093B (en) * 2018-10-29 2021-06-01 湖北丽益医药科技有限公司 HPLC detection method of valganciclovir hydrochloride intermediate condensation compound isomer

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5700936A (en) * 1996-01-26 1997-12-23 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
US5840890A (en) * 1996-01-26 1998-11-24 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US20080076923A1 (en) * 2006-06-21 2008-03-27 Solmag S.P.A.. Process for the preparation and purification of valgancyclovir

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5700936A (en) * 1996-01-26 1997-12-23 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
US5840890A (en) * 1996-01-26 1998-11-24 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US20080076923A1 (en) * 2006-06-21 2008-03-27 Solmag S.P.A.. Process for the preparation and purification of valgancyclovir

Also Published As

Publication number Publication date
WO2010036904A2 (en) 2010-04-01

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