WO2009104809A1

WO2009104809A1 - Liquid filled body for invasive arterial-pressure monitoring system and method for producing the same

Info

Publication number: WO2009104809A1
Application number: PCT/JP2009/053476
Authority: WO
Inventors: 健島本
Original assignee: Shimamoto Takeshi
Priority date: 2008-02-22
Filing date: 2009-02-19
Publication date: 2009-08-27
Also published as: JP2009195579A; JP4214170B1

Abstract

Provided is a filling-liquid filled body used for an invasive arterial-pressure monitoring system and filled with filling liquid, wherein internal deaeration is performed positively, assembling work requires only a short time, and emergency can be handled easily. The liquid filled body comprises a medical tube body (10) filled with filling liquid, a first connection structure (30) having a sealed distal end provided at one end of the medical tube body (10) and being connectible to an indwelling needle (200) which is punctured into a patient, and a second connection structure (40) having a sealed distal end provided at the other end of the medical tube body (10) and being connectible to a filling liquid bag (300). A transducer portion (20) is provided near the middle of the medical tube body (10). Deaeration is performed positively by supplying the filling liquid from a liquid-injecting three-way stopcock (13) near the side of the transducer portion (20) while deaeration is performed during production.

Description

MEI HOSHI 液体 Liquid inclusion body for invasive arterial pressure monitoring system and production method thereof Technical Field

The present invention relates to a circuit (exclusive line) for supplying a filling liquid in an invasive monitoring system. The filling solution may be a high-concentration solution in which a solute is dissolved at a high concentration, such as physiological saline, heparin-added physiological saline with heparin added, 10% sodium chloride solution, 50% sugar solution, etc. good. Background art

Open blood pressure monitoring systems are widely used to monitor heart rate and blood pressure fluctuations in patients with unstable cardiac function and blood pressure. For example, it is widely used for hemodynamic monitoring and condition monitoring of patients in the intensive care unit (ICU) for catheter examinations in cardiovascular surgery and cardiovascular medicine.

The invasive arterial pressure monitoring system obtains various data on arterial pressure by directly monitoring blood pressure fluctuations in the blood vessel via an indwelling needle drilled in the blood vessel of the patient. A filling solution such as physiological saline is supplied to the indwelling needle, and monitoring is performed with a transducer that senses pressure using the filling solution as a medium.

The circuit that conducts this filling liquid from the filling liquid bag (a soft 50cc bag filled with the filling liquid) to the indwelling needle is called a dedicated line, which consists of a pre-sterilized medical tube. In the line path, a transducer is provided with a transducer that senses pressure from the flowing blood flow, and a cable for outputting data to the monitor main unit. Is provided.

In addition, the same type of liquid can be put into the dedicated line filling liquid bag. For example, when using heparin-added saline with heparin added as the filling solution, heparin-added saline is used for both the dedicated line and the filling solution bag.

This invasive arterial pressure monitoring system is dynamically assembled and used by the following procedure immediately before being used in an operating room or the like.

(Procedure 1) Connect the filling liquid bag to the dedicated line, and connect the filling liquid bag to the dedicated line.

(Procedure 2) Fill the filling liquid by pouring the filling liquid from the filling liquid bag into the dedicated line.

(Procedure 3) After removing the buffering air enclosed in the filling liquid bag, pressurize the filling liquid bag with a pressure bag and pressurize until the pressure becomes 30 O m m H g.

By setting the pressure of the filling fluid bag to 300 mm Hg, the blood pressure is appropriately higher than the arterial pressure of the patient, so that the blood flow does not flow back into the dedicated line and Therefore, the filling liquid can be introduced appropriately.

(Procedure 4) Thoroughly vent the fine bubbles in the dedicated line, and drop a little liquid.

(Procedure 5) Connect to the indwelling needle punctured into the patient's artery and connect the cable to the monitor main unit.

Changes in arterial pressure in the dedicated line are converted into electrical signals using a transducer, and signal processing is performed in the main unit via a cable to display graphs and numerical values such as heart rate and blood pressure on the display device.

Filling fluid bag and dedicated line for invasive arterial pressure monitoring It was necessary to perform the above procedure in every rotation.

Patent Document 1 Japanese Patent Laid-Open No. 2 0 0 6-3 4 6 4 5 1 Disclosure of Invention

Problems to be solved by the invention

The assembly of the filling bag and the dedicated line of the conventional invasive arterial pressure monitoring system has the following problems.

The first problem is that assembly takes time.

The assembly of the filling fluid bag and the dedicated line of the conventional invasive arterial pressure monitoring system requires the above five procedures, so even a skilled nurse is said to take about 10 minutes. This time of 10 minutes is precious and regarded as a problem in the medical field.

Of the above five procedures, the particularly time-consuming work is the work of properly removing the air in the dedicated line and the filling liquid bag and filling the dedicated line with the filling liquid. If air remains in the dedicated line, the air may enter the artery as it is, so thorough air bleeding is required. If air enters the artery, it becomes arterial embolism and may cause ischemia of peripheral extremity. However, it is difficult to reliably remove fine air from this dedicated line, and it takes time to do so carefully.

The second problem is the difficulty of dealing with urgency.

The invasive monitoring system is used in emergency surgery for acute heart diseases such as myocardial infarction and heart failure patients, and is also used in emergency surgery for sudden accidents such as traffic accidents. When dealing with such an urgency, we are competing for 1 minute and 1 second, and in this situation we have a nurse take care of assembling an invasive monitoring system that takes nearly 10 minutes. This is a heavy burden.

In particular, there is a need for a pre-filled dedicated line that eliminates the need for time-consuming air bleed operations, but currently no such pre-filled dedicated line is available. Moreover, in the case of cardiovascular surgery, it is necessary to prepare a plurality of such invasive monitoring systems for monitoring systemic arterial pressure and for monitoring pulmonary artery, which further increases the burden.

In view of the above problems, the present invention provides a liquid enclosure for an invasive arterial pressure monitoring system that can be assembled in a short period of time and can be easily handled in an emergency, and a method for producing the same. The purpose is to do. Means for solving the problem

In order to achieve the above object, a liquid inclusion body for an invasive arterial pressure monitoring system of the present invention comprises:

Fluid for an invasive arterial pressure monitoring system that measures the state of the patient's artery by detecting the state of the filling fluid filled in the dedicated line that has invaded the patient's artery via the indwelling needle with a transducer. An inclusion body, the medical tube body filled with the filling liquid;

A first connection structure provided at the one end of the medical tube body and sealed at the tip thereof, connectable to the indwelling needle;

A second connection structure provided at the other end of the medical tube body and sealed at the tip thereof, connectable to the filling liquid pug;

A part of the transducer provided near the middle of the medical tube body is provided.

With the above configuration, a pre-filled solution can be prepared in advance, and assembly with an indwelling needle and a solution bag can be completed on the spot in a short time. It is possible to provide an invasive monitoring system that can easily cope with an emergency.

Next, the liquid enclosure for the invasive arterial pressure monitoring system has a liquid reservoir portion that can be pressed by the first connection structure in the above-described configuration, and is provided at the tip of the first connection structure. When the seal is broken and connected to the indwelling needle, it is possible to connect the indwelling needle while pressing the liquid reservoir and dripping the filling liquid from the tip to release the air. .

In addition, the liquid enclosure for the invasive arterial pressure monitoring system in the above-described configuration includes a liquid reservoir that can be pressed by the second connection structure, and seals the tip of the second connection structure. It is possible to connect to the filling liquid bag while releasing the air by releasing the air by dropping the filling liquid from the tip by pressing the liquid reservoir when connecting to the filling liquid bag.

With the above configuration, when the sealed first connection structure and second connection structure are opened, a small amount of air may be mixed in from the opening, but a liquid reservoir is provided. It is possible to connect the indwelling needle and the filling liquid bag while pushing the liquid reservoir while dripping the tip of the needle upwards and dropping the filling liquid to push the air outward. You can.

Next, the liquid enclosure for the invasive arterial pressure monitoring system has the above-described configuration, wherein the medical tube body includes the three-way stopcock provided near a part of the transducer of the medical tube body. The filling liquid is injected toward the tip of the first connection structure and the tip of the second connection structure, and the filling liquid is sealed in the medical tube body.

According to the above configuration, when the filling liquid is injected into the liquid enclosure, if the air is injected from the vicinity of the remaining thin transducer, the air is released. It reduces the risk of air remaining.

Next, a first method for producing a liquid inclusion body for the invasive arterial pressure monitoring system of the present invention is as follows.

Fluid for an invasive arterial pressure monitoring system that measures the state of the patient's artery by detecting the state of the filling fluid filled in the dedicated line that has invaded the patient's artery via the indwelling needle with a transducer. A method for producing inclusion bodies,

The first connecting structure that can be connected to the indwelling needle is at one end, the second connecting structure that can be connected to the filling liquid bag is at the other end, and a part of the transducer is injected near the middle, and the filling liquid is injected. For a medical tube body with a three-way stopcock for liquid injection near the transducer,

The vicinity of the liquid injection three-way stopcock is kept low, the first connection structure and the second connection structure are kept high, and the filling liquid is supplied from the liquid injection three-way stopcock located on the lower side at a predetermined pressure. After injecting and surely venting the transducer part, the first connection structure, and the second connection structure, the tip of the liquid injection three-way cock and the first connection structure In this method, the tip and the tip of the second connection structure are sealed.

According to the above production method, when the filling liquid is injected into the liquid enclosure, if the air is injected from the vicinity of the transducer where the air is likely to remain, the air in the transducer may be vented and the air may remain. Is reduced.

For example, when a mechanism for increasing the internal pressure of the dedicated line to a predetermined pressure is incorporated in the vicinity of the transducer, it is preferable to inject the filling liquid at a predetermined pressure while releasing the pressure increasing mechanism.

Next, a second method for producing a liquid inclusion body for the invasive arterial pressure monitoring system of the present invention is as follows. Liquid filling for an invasive arterial pressure monitoring system that measures the state of the patient's artery by detecting the state of the filling fluid filled in the dedicated line that has invaded the patient's artery via the indwelling needle. A method of producing a body,

The first connection structure that can be connected to the indwelling needle at one end, the second connection structure that can be connected to the filling liquid bag at the other end, and a medical tube body that has a part of the transducer near the middle for,

Either one of the first connection structure or the second connection structure is lowered, and the other part of the first connection structure or the second connection structure is placed in the middle of the transducer part. The filling liquid is injected at a predetermined pressure from the lower side, and the filling liquid is recovered from the upper side, and the first connection structure In addition, after the air is released from the transducer part and the second connection structure with certainty, the tip of the first connection structure and the tip of the second connection structure are sealed. According to the above production method, when the filling liquid is injected into the liquid enclosure, air is likely to remain, and if it is injected toward the second connection structure located higher than the vicinity of the transducer, the transducer air The removal becomes less and the possibility of air remaining is reduced.

In the above production method, it is preferable to vibrate fine bubbles by giving vibration to a part of the transducer, the first connection structure, and the second connection structure when the air is released. With the above configuration, fine air can be exhausted thoroughly. The filling liquid used in the liquid inclusion body for the invasive arterial pressure monitoring system of the present invention and the filling liquid used in the method for producing the liquid sealing body for the invasive arterial pressure monitoring system of the present invention The liquid is preferably a physiological saline that has been deaerated to reduce the air dissolved in the liquid. Also filling liquid For example, physiological saline without other additives may be used, and other additives, for example, heparin-added physiological saline with heparin added may be used. Alternatively, a soot-concentration solution in which a solute is dissolved at a high concentration such as 10% sodium chloride solution or 50% sugar solution may be used. If the liquid to be filled is degassed or the solute concentration of the liquid to be filled is increased, the amount of air dissolved in the filling liquid can be reduced, and minute air bubbles are formed in the liquid enclosure. The risk of precipitation is reduced. Brief Description of Drawings

FIG. 1 is a diagram schematically showing a configuration example of a liquid enclosure 100 of the present invention.

FIG. 2 is a view showing a structure example in which the tip of the second connection structure is sealed using a twisted cap that is a pseudo needle.

FIG. 3 is a diagram schematically showing a procedure for constructing an invasive arterial pressure monitoring system using the liquid inclusion body 100.

FIG. 4 is a diagram showing a construction example of an invasive arterial pressure monitoring system. FIG. 5 is a diagram schematically showing the filling liquid filling and air bleeding directions in the first production method of the liquid enclosure 100 of the present invention.

FIG. 6 is a diagram schematically showing the filling liquid and the direction of air bleeding in the second production method of the liquid enclosure 100 of the present invention. BEST MODE FOR CARRYING OUT THE INVENTION

Hereinafter, the best mode for carrying out the present invention will be specifically described by way of examples. The present invention is not limited to these examples. '

Hereinafter, a liquid enclosure for an invasive arterial pressure monitoring system of the present invention and a method for producing the same will be described in detail with reference to the embodiments shown in the accompanying drawings. In addition, The present invention is not limited to these examples.

(Example 1)

A liquid enclosure 100 for an invasive arterial pressure monitoring system according to Embodiment 1 of the present invention will be described.

FIG. 1 is a diagram schematically showing a configuration example of a liquid enclosure 100 according to Embodiment 1 of the present invention. In addition, when constructing an invasive arterial pressure monitoring system, the indwelling needle 20 0 inserted into the patient, the filling fluid bag 3 0 0, and the invasive blood pressure monitoring system main unit 4 0 0 are also included. Are shown.

As shown in FIG. 1, the liquid enclosure 10 100 of the present invention includes a medical tube 10, a transducer part 20, a first connection structure 30, and a second connection structure 40. ing. The filling liquid filled inside may be a physiological saline without other additives, or other additives, for example, heparin-added physiological saline with heparin added. Any additives to which additives that can be used are added may be used. Here, the filling liquid to be sealed is preferably a liquid which has been subjected to a deaeration process for reducing the air dissolved in the liquid. The liquid may be physiological saline or heparin-added physiological saline to which other additives (eg, heparin) are added. Alternatively, a high concentration solution in which a solute is dissolved at a high concentration such as 10% sodium chloride solution or 50% sugar solution may be used. If the liquid to be filled is degassed or the solute concentration of the liquid to be filled is increased, the amount of air dissolved in the filling liquid can be reduced, and minute air bubbles are formed in the liquid enclosure. It becomes difficult to precipitate.

The medical tube 10 is filled with a filling liquid. It may be made of a soft bure for medical tubes, and is set to an internal pressure of 300 mm Hg, which is higher than the arterial pressure when boosted by connecting to a filling liquid bag 300 as will be described later. Therefore, it is necessary to be able to withstand the internal pressure sufficiently. The material must be able to withstand sterilization chemicals. The medical tube 1 o has a force s that is tubularly connected from one end to the other end, the first medical tube part 1 1, the air vent three-way cock 1 2, the liquid injection three-way cock 1 3, the second tube Each of the parts 14 and the second liquid reservoir 15 is provided.

The first medical tube portion 11 is a portion from the tip of the first connection structure 30 to the liquid injection three-way cock 13. Note that the front end of the first connection structure 30 is sealed.

The air vent three-way stopcock 12 is provided in the vicinity of the first connection part 30. When the indwelling needle 20 00 is inserted into the patient and the first connection part 30 of the arterial pressure line is connected, the connection part This is a part for extracting the remaining air. For example, in the process of collecting the patient's blood from the indwelling needle 20 0, it is possible to simultaneously release the air from the connection portion of the first connection portion 30 of the arterial pressure line.

In the configuration of FIG. 1, the air vent three-way stopcock 12 is provided in the vicinity of the first connection part 30. However, the present invention is not limited to this position, and the three-way stopcock for injecting liquid from the vicinity of the first connection part 30 The first medical tube portion 11 may be located anywhere in place, and the air venting three-way stopcock 12 and a liquid injection three-way stopcock 13 described later may serve as a single three-way stopcock.

The liquid injection three-way stopcock 13 is a portion that serves as an inlet for injecting the filling liquid in the process of producing the liquid enclosure 10 100 as will be described later. The part is provided in the vicinity of the transducer part 20. Liquid injection three-way stopcock 1 If the filling liquid is injected from the 3 inlet, the filling liquid is injected into both the left and right first medical tube parts 1 1 and the second medical tube part 1 4 at the same time. It will be done.

The second medical tube portion 14 is a portion from the tip of the second connection structure 40 to the liquid injection three-way stopcock 13. Note that the front end of the second connection structure 40 is sealed. The second liquid reservoir 15 is a buffer portion that becomes a liquid reservoir for the second medical tube portion 14 near the second connection structure 40, and can be easily used by a nurse or the like as will be described later. The air can be pressed and the air venting is smooth.

The transducer part 20 is a sensor part provided in a part of the medical tube 10, and the wall of the medical tube 10 inside the transducer part 20 is thin and flexible, and the internal pressure changes. The wall surface is easy to vibrate according to the sensor, and is provided with a sensor for detecting the vibration of the wall surface inside the transducer part 20. The sensor may be any sensor that can detect a change in hydraulic pressure, such as a pressure sensor. The fluctuation of the internal pressure in the medical tube 10 detected by the transducer part 20 is output as an electrical signal and transmitted to the invasive arterial pressure monitor system main unit 40 0 via the connector.

The first connection structure 30 is a connector that can be connected to an indwelling needle 20 0 drilled in a patient. The connector structure may be one corresponding to the indwelling needle 200.

In the normal state, the tip of the first connection structure 30 is sealed so as not to leak. When constructing an invasive arterial pressure monitoring system, a structure that can be opened quickly is preferable. For example, if the vinyl tube is sealed by thermocompression bonding, the tip of the vinyl tube may be threaded. Also, if it is screwed and sealed with a screw cap, it can be easily removed with a human finger or hand, such as turning the cap to easily unscrew and open the tip. The

The second connection structure 40 is a connector that can be connected to the filling liquid bag 30. A connector structure corresponding to the filling liquid bag 300 may be employed.

When in regular use, the tip of the second connection structure 40 is sealed to prevent liquid leakage. It is. When constructing an invasive arterial pressure monitoring system, a structure that can be opened quickly is preferable. For example, if the bull tube is sealed by thermocompression bonding, the tip of the bull tube may be threaded off. In addition, if it is screwed and sealed with a screw cap, it can be easily removed with a human finger or hand, such as turning the cap to easily unscrew and open the tip. The

Also, instead of using a screw cap or other mechanism to remove with a finger or hand, it is also possible to use a twist cap that is a pseudo needle as shown in Fig. 2. A needle 41 is provided at the tip of the second connection structure 40, and a twist cap 42 is provided so as to cover the needle 41. That is, the needle 41 is completely sealed by the second connection structure 40 and the twist cap 42. As shown in FIG. 2 (a), the tip of the twist cap 42 is needle-shaped and can be connected to the filling liquid bag 300 as a pseudo needle as shown in FIG. 2 (b). It is like that. After inserting the tip of the twisting cap 4 2 of the second connection structure 40 into the filling liquid bag 30 0, the second connection structure 40 is pressed while holding the twisting cap 42 as shown in FIG. 2 (c). When the twisted cap 4 2 is twisted by rotating the connecting structure 4 0 to the left and right, the needle 41 is exposed as shown in FIG. 2 (d), and the filling liquid bag 3 0 0 and the second The connection structure 40 is electrically connected, and the filling liquid can be taken in.

Next, a procedure for constructing an invasive arterial pressure monitoring system using the liquid inclusion body 100 will be described.

FIG. 3 is a diagram schematically showing a procedure for constructing an invasive arterial pressure monitoring system using the liquid inclusion body 100 according to the first embodiment.

(Procedure 1) First, as shown in FIG. 3 (a), the tip of the second connection structure 40 of the liquid enclosure 100 is unsealed and opened, and the second liquid reservoir 15 is removed. Press with your finger and let it drip from the tip while preventing air from entering. The connecting structure 40 is connected to the connection port of the filling liquid bag 30, and the filling liquid bag and the liquid enclosure 10 100 are electrically connected. The filling liquid bag and the liquid enclosure 100 can be made conductive without mixing air.

(Procedure 2) Pressurize the filling liquid bag with a pressure bag and pressurize until the pressure reaches 300 m Hg. The internal pressure of the liquid enclosure 100 connected to the filling liquid bag is also increased to 300 mm Hg. When buffering air is sealed in the filling liquid bag, the buffering air is removed before pressurizing with the pressurizing bag.

(Procedure 3) As shown in Fig. 3 (b), the first connection of the liquid enclosure 100 is unsealed and opened to prevent air from entering. The structure 30 is connected to an indwelling needle pierced into the patient's artery, and the human artery is connected to the liquid enclosure 100. Connect the cable to the monitor main unit.

Changes in internal pressure of the medical tube 10 due to changes in arterial pressure are captured by the transducer 20 and converted into electrical signals, and signal processing is performed in the main unit via a cable, and the heart rate and blood pressure are applied to the display device. Display graphs and numerical values.

As a means for removing a small amount of residual air that may be generated when the first connection structure 30 is connected to the indwelling needle 20 0, there is a means using an air vent three-way cock 12. The air vent three-way stopcock 12 can be used to collect blood from the patient's blood vessel via the indwelling needle 20 0, and it is also possible to vent the remaining small amount of air.

By the above three procedures, it is possible to construct an open arterial pressure moeta system as shown in Fig. 4 in a short time and easily. As shown in the prior art, the conventional method requires five procedures. According to the liquid enclosure 10 of the present invention, the filling operation of the filling liquid into the medical tube 10 is particularly performed compared to the conventional method. Nya Labor saving is saved.

Next, a method for producing the liquid enclosure 100 according to the present invention will be described.

The liquid enclosure 100 is filled and filled with a filling liquid, but it is necessary to vent the air thoroughly. The inside of the medical tube 10 is not a simple tube, but there are structures such as a transducer part 20 in particular, and air is likely to accumulate, and in the mass production process, air bleeding becomes a problem.

First, the first production method is described.

FIG. 5 is a diagram schematically illustrating the filling liquid filling and air bleeding directions in the first production method of the liquid enclosure 100 of the present invention. In FIG. 5, only the supply pipe 5 10 and the T-shaped discharge pipe 5 20 are shown in the configuration of the sealing device 500 used in the first production method. Although not shown in the figure, the main body of the sealing device 500 has a function of filling the filling liquid into the dedicated line from the supply pipe 5 10 and collecting the filling liquid overflowing from the T-shaped discharge pipe 5 20. It is.

The supply pipe 51 is located in the lower part, and supplies the filling liquid dropwise from below to above. The T-shaped discharge pipe 5 20 is located in the upper part, and receives and collects the liquid flow of the filling liquid that flows separately from the lower part.

As shown in FIG. 5, the liquid enclosure 100 is connected to the supply pipe 5 10 with the liquid injection three-way stopcock 13 located at the lowest position, and the first connection structure 30 and the second The connecting structure 40 is set in the enclosure so as to be connected to the T-shaped discharge pipe 5 20. As described above, the liquid infusion way stopcock 1 3 is provided in the vicinity of Toransude Yusa part ₂ 0 is located at the lowest generally part 2 0. transducer.

As shown in FIG. 5, gently inject the filling liquid from the supply pipe 5 10 toward the liquid injection three-way stopcock 13. Filling liquid is three-way stopcock. At the same time, the medical tube 10 is filled. That is, the vicinity of the liquid injection three-way stopcock 1 3 is kept low, the first connection structure 30 and the second connection structure 40 are kept high, and the filling liquid is predetermined from the liquid injection three-way stopcock 13 located on the lower side. Inject with pressure.

The filling liquid is divided into left and right from the liquid injection three-way stopcock 13 and rises toward the first connection structure 30 and the second connection structure 40, and the air vent three-way stopcock 12 and second The liquid reservoir 15 is filled, and the liquid is collected from the T-shaped discharge pipe 5 20 through the first connection structure 30 and the second connection structure 40. Here, in the first embodiment, when venting the air, a device for giving a vibration to the transducer part 20, the first connection structure 30, and the second connection structure 40 to knock out fine bubbles. Do. By applying vibration in this way, fine bubbles are knocked out, the bubbles rise in the medical tube 10 along the flow of the filling liquid, and the air remaining in each part is surely removed. I can leave. As a method for providing vibration, a motor-type vibrator or ultrasonic vibrator may be applied to the medical tube 10 or the like to vibrate.

Thereafter, the tip portion of the first connection structure 30 and the connection portion of the second connection structure 40 are respectively sealed to seal the filling liquid inside. For example, as a sealing method, it may be sealed by pressing a soft vinyl tube by thermocompression. Liquid injection three-way stopcock 1 3 Close the stopcock so that the filling liquid does not leak.

The above production method can also be used in a mass production process, and the liquid enclosure 10 of the present invention can be produced.

Next, the second production method will be described.

FIG. 6 is a diagram schematically showing the filling liquid filling and air bleeding directions in the second production method of the liquid enclosure 100 of the present invention. Figure 6 shows the second Only the supply pipe 5 1 0 a and the discharge pipe 5 2 0 a are illustrated in the configuration of the sealing device 5 0 0 used in this production method. The body part of the sealing device 500 is not shown, but as in FIG. 5, the filling liquid is filled into the dedicated line from the supply pipe 5 1 0 a and the filling liquid overflowing from the discharge pipe 5 2 0 a It has a function to collect.

The supply pipe 5 10 a is located at the lower part, and supplies the filling liquid dropwise from below to above. The discharge pipe 5 2 0 a is located at the upper part and receives and collects the filling liquid flowing from below.

The liquid enclosure 10 0 lowers either the first connection structure 30 or the second connection structure 40, and places the transducer part 20 in the middle, so that the first connection structure 3 0 or the second connection structure 40 Keeping the other 0 high, the filling liquid is injected at a predetermined pressure from the lower position, and the filling liquid is recovered from the upper position. By doing. Fill the filling liquid. In the example of FIG. 6, as an example, the first connection structure 30 is positioned below and the second connection structure 40 is positioned above.

In the state of FIG. 6, the tip of the first connection structure 30 is connected to the supply pipe 5 10 0 a, the tip of the second connection structure 40 is connected to the discharge pipe 5 2 0 a, and the supply By dropping the filling liquid upward from the pipe 5 10 a, the filling liquid rises toward the second connection structure 40, and the air vent three-way stopcock 1 2, the transducer part 20, the first The second liquid reservoir 15 is filled, and the liquid is collected from the discharge pipe 5 20 a through the second connection structure 40.

In this example as well, it is preferable to devise a method to vibrate fine bubbles by giving vibration to the transducer part 20, the first connection structure 30, and the second connection structure 40 when releasing air. By applying the pie brasion, fine bubbles are knocked out, and the bubbles rise in the medical tube 10 along the flow of the filling liquid and remain in each part. Can be removed without fail.

Thereafter, two portions of the tip portion of the first connection structure 30 and the connection portion of the second connection structure 40 are sealed to seal the filling liquid inside. For example, as a sealing method, the soft vinyl tube may be pressed and sealed by thermocompression.

As described above, according to the liquid enclosure 10 100 of the present invention according to the first embodiment, it is possible to always prepare a pre-filled filling liquid, and to easily place the indwelling needle and the filling liquid bag on the spot for a short time. As a result, it is possible to provide an invasive monitoring system that can be easily assembled in an emergency.

As described above, the preferred embodiment of the configuration example of the liquid enclosure according to the present invention has been illustrated and described, but it will be understood that various modifications can be made without departing from the technical scope of the present invention. .

Although the preferred embodiments of the present invention have been illustrated and described above, it will be understood that various modifications can be made without departing from the technical scope of the present invention. Therefore, the technical scope of the present invention is limited only by the description of the appended claims.

Industrial applicability

The liquid inclusion body of the present invention can be used in an invasive monitoring system.

Claims

The scope of the claims

1. For an arterial pressure monitoring system for measuring the arterial state of a patient by detecting the state of the filling liquid filled in a dedicated line invading the patient's artery via an indwelling needle with a transducer. A medical tube body filled with the filling liquid,

A second connection structure provided at the other end of the medical tube body and sealed at the tip thereof, and connectable to the filling liquid bag;

A liquid enclosure for an invasive arterial pressure monitoring system, comprising a part of a transducer provided near the middle of the medical tube body.

2. The first connection structure includes a liquid reservoir that can be pressed, and when the first connection structure is broken to seal the tip of the first connection structure and connected to the indwelling needle, the liquid reservoir is pressed to 2. The liquid enclosure for an invasive arterial pressure monitoring system according to claim 1, wherein the filling liquid can be dropped from the tip and connected to the indwelling needle while releasing air.

3. The second connection structure is provided with a pressurizable liquid reservoir, and when the second connection structure is broken and sealed at the tip of the second connection structure, the liquid reservoir is pressed. 3. The liquid enclosure for an invasive arterial pressure monitoring system according to claim 1 or 2, wherein the filling liquid is dropped from the tip to be evacuated and connected to the filling liquid bag.

4. From a three-way cock provided near a part of the transducer of the medical tube body toward the leading end of the first connection structure and the distal end of the second connection structure of the medical tube body The filling liquid according to claim 1, wherein the filling liquid is injected, and the filling liquid is sealed in the medical tube body. Liquid enclosure for the invasive arterial pressure monitoring system.

5. The physiological saline solution according to any one of claims 1 to 4, wherein the filling liquid is a physiological saline that has been subjected to a deaeration process for reducing air dissolved in the liquid. Inclusion body.

6. The liquid enclosure according to any one of claims 1 to 4, wherein the filling liquid is high-concentration saline or high-concentration sugar liquid.

7. The liquid inclusion body for an invasive arterial pressure monitoring system according to any one of claims 1 to 6, wherein the filling liquid is heparin-added physiological saline to which heparin is added.

8. For an invasive arterial pressure monitoring system that measures the patient's arterial state by detecting the state of the filling liquid filled in a dedicated line that has invaded the patient's artery via an indwelling needle with a transducer. A method for producing a liquid enclosure of

The vicinity of the liquid injection three-way cock is low, the first connection structure and the first

The connection structure of 2 is kept high, and the filling liquid is injected at a predetermined pressure from the liquid injection three-way cock located on the lower side, and the transducer part, the first connection structure, and the After reliably venting the second connection structure, invasive arterial pressure that seals the tip of the three-way stopcock, the tip of the first connection structure, and the tip of the second connection structure Production method of liquid enclosure for monitoring system.

9. The state of the filling liquid filled in the dedicated line that has invaded the patient's artery via the indwelling needle is detected by a transducer, and the movement of the patient is detected. A method of producing a liquid inclusion for an invasive arterial pressure monitoring system for measuring a pulse state comprising:

Either one of the first connection structure or the second connection structure is lowered, and the other part of the first connection structure or the second connection structure is placed in the middle of the transducer part. The filling liquid is injected at a predetermined pressure from the lower side, and the first filling structure is recovered from the upper side. And the second connecting structure is surely vented, and then the invasive arterial pressure module is used to seal the tip of the first connecting structure and the tip of the second connecting structure. A method for producing a liquid enclosure for a two-part system.

10. The method according to claim 8, wherein when the air is released, a fine bubble is knocked out by applying a vibration to the part of the transducer, the first connection structure, and the second connection structure. 10. A method for producing a liquid inclusion body for the invasive arterial pressure monitoring system according to 9.

11. The liquid filling according to any one of claims 8 to 9, wherein the filling liquid is a physiological saline that has been subjected to a deaeration process for reducing air dissolved in the liquid. Body production method.

12. The method for producing a liquid enclosure according to any one of claims 8 to 9, wherein the filling liquid is a high-concentration saline or a high-concentration sugar liquid.

1 3. The method for producing a liquid inclusion body for an invasive arterial pressure monitor system according to any one of claims 8 to 12, wherein the filling liquid is a heparin-added physiological saline to which heparin is added. .