WO2009098149A3 - Verfahren zur gewinnung olfaktorischer epithelzellen aus nicht-menschlichen embryonalen stammzellen - Google Patents

Verfahren zur gewinnung olfaktorischer epithelzellen aus nicht-menschlichen embryonalen stammzellen Download PDF

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Publication number
WO2009098149A3
WO2009098149A3 PCT/EP2009/050908 EP2009050908W WO2009098149A3 WO 2009098149 A3 WO2009098149 A3 WO 2009098149A3 EP 2009050908 W EP2009050908 W EP 2009050908W WO 2009098149 A3 WO2009098149 A3 WO 2009098149A3
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WIPO (PCT)
Prior art keywords
extracting
epithelial cells
olfactory epithelial
embryonic stem
human embryonic
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PCT/EP2009/050908
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English (en)
French (fr)
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WO2009098149A2 (de
Inventor
Daniela KEßLER-BECKER
Dirk Petersohn
Heribert Bohlen
Kristina JÖNSSON
Andreas Ehlich
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Henkel Ag & Co. Kgaa
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Publication of WO2009098149A2 publication Critical patent/WO2009098149A2/de
Publication of WO2009098149A3 publication Critical patent/WO2009098149A3/de

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    • C12N5/0618—Cells of the nervous system
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
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Abstract

Die vorliegende Erfindung betrifft ein Verfahren zur Gewinnung olfaktorischer Epithelzellen aus nicht-menschlichen embryonalen Stammzellen, olfaktorische Epithelzellen, die mittels des erfindungsgemäßen Verfahrens gewonnen wurden sowie Testsysteme für kosmetische und/oder pharmazeutische Zubereitungen auf der Basis olfaktorischer Epithelzellen, die mittels des erfindungsgemäßen Verfahrens gewonnen wurden.
PCT/EP2009/050908 2008-02-08 2009-01-28 Verfahren zur gewinnung olfaktorischer epithelzellen aus nicht-menschlichen embryonalen stammzellen WO2009098149A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200810008558 DE102008008558A1 (de) 2008-02-08 2008-02-08 Verfahren zur Gewinnung olfaktorischer Epithelzellen aus nicht-menschlichen embryonalen Stammzellen
DE102008008558.8 2008-02-08

Publications (2)

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WO2009098149A2 WO2009098149A2 (de) 2009-08-13
WO2009098149A3 true WO2009098149A3 (de) 2009-10-01

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PCT/EP2009/050908 WO2009098149A2 (de) 2008-02-08 2009-01-28 Verfahren zur gewinnung olfaktorischer epithelzellen aus nicht-menschlichen embryonalen stammzellen

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DE (1) DE102008008558A1 (de)
WO (1) WO2009098149A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3110464A1 (en) * 2018-08-24 2020-02-27 Sumitomo Chemical Company, Limited Cell cluster including olfactory neuron or precursor cell thereof, and method for producing same

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US5308763A (en) * 1991-10-01 1994-05-03 The Johns Hopkins University Method of making primary culture of olfactory neurons
US5380651A (en) * 1990-12-31 1995-01-10 The Johns Hopkins University Method of determining odorant compounds and antagonists of odorants using a primary culture of olfactory neurons
US5639618A (en) * 1994-05-13 1997-06-17 Plurion, Inc. Method of isolating a lineage specific stem cell in vitro
WO2001051609A1 (en) * 2000-01-14 2001-07-19 The Johns Hopkins University Isolation and in vitro differentiation of conditionally immortalized murine olfactory receptor neurons
WO2003064601A2 (en) * 2002-01-28 2003-08-07 University Of Louisville Research Foundation, Inc. Adult human olfactory stem cell
US20040029269A1 (en) * 2002-05-07 2004-02-12 Goldman Steven A Promoter-based isolation, purification, expansion, and transplantation of neuronal progenitor cells, oligodendrocyte progenitor cells, or neural stem cells from a population of embryonic stem cells
US20070172946A1 (en) * 1998-04-14 2007-07-26 The University Court Of The University Of Edinburgh Lineage specific cells and progenitor cells

Patent Citations (7)

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Publication number Priority date Publication date Assignee Title
US5380651A (en) * 1990-12-31 1995-01-10 The Johns Hopkins University Method of determining odorant compounds and antagonists of odorants using a primary culture of olfactory neurons
US5308763A (en) * 1991-10-01 1994-05-03 The Johns Hopkins University Method of making primary culture of olfactory neurons
US5639618A (en) * 1994-05-13 1997-06-17 Plurion, Inc. Method of isolating a lineage specific stem cell in vitro
US20070172946A1 (en) * 1998-04-14 2007-07-26 The University Court Of The University Of Edinburgh Lineage specific cells and progenitor cells
WO2001051609A1 (en) * 2000-01-14 2001-07-19 The Johns Hopkins University Isolation and in vitro differentiation of conditionally immortalized murine olfactory receptor neurons
WO2003064601A2 (en) * 2002-01-28 2003-08-07 University Of Louisville Research Foundation, Inc. Adult human olfactory stem cell
US20040029269A1 (en) * 2002-05-07 2004-02-12 Goldman Steven A Promoter-based isolation, purification, expansion, and transplantation of neuronal progenitor cells, oligodendrocyte progenitor cells, or neural stem cells from a population of embryonic stem cells

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Title
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HANSEL D E ET AL: "REGULATION OF OLFACTORY NEUROGENESIS BY AMIDATED NEUROPEPTIDES", JOURNAL OF NEUROSCIENCE RESEARCH, WILEY-LISS, US, vol. 66, no. 1, 1 October 2001 (2001-10-01), pages 1 - 07, XP008022866, ISSN: 0360-4012 *
MURRELL J R ET AL: "AN OLFACTORY SENSORY NEURON LINE, ODORA, PROPERLY TARGETS OLFACTORYPROTEINS AND RESPONDS TO ODORANTS", JOURNAL OF NEUROSCIENCE, NEW YORK, NY, US, vol. 19, no. 19, 1 October 1999 (1999-10-01), pages 8260 - 8270, XP002938275, ISSN: 0270-6474 *
YEE K K ET AL: "Immunolocalization of retinoic acid receptors in the mammalian olfactory system and the effects of olfactory denervation on receptor distribution", NEUROSCIENCE, NEW YORK, NY, US, vol. 131, no. 3, 1 January 2005 (2005-01-01), pages 733 - 743, XP025366758, ISSN: 0306-4522, [retrieved on 20050101] *

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DE102008008558A1 (de) 2009-08-13

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