WO2009091206A3 - 5'-구아노신 모노포스페이트 생산능이 향상된 코리네박테리움 속 미생물 및 이를 이용한 5'-구아노신 모노포스페이트의 생산방법 - Google Patents

5'-구아노신 모노포스페이트 생산능이 향상된 코리네박테리움 속 미생물 및 이를 이용한 5'-구아노신 모노포스페이트의 생산방법 Download PDF

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Publication number
WO2009091206A3
WO2009091206A3 PCT/KR2009/000238 KR2009000238W WO2009091206A3 WO 2009091206 A3 WO2009091206 A3 WO 2009091206A3 KR 2009000238 W KR2009000238 W KR 2009000238W WO 2009091206 A3 WO2009091206 A3 WO 2009091206A3
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Prior art keywords
phosphate
guanosine
guanosine mono
microorganism
mono
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PCT/KR2009/000238
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English (en)
French (fr)
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WO2009091206A2 (ko
Inventor
김철하
최종수
조진만
홍국기
이지혜
이진남
오윤석
박장희
김혜원
이승범
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씨제이제일제당(주)
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Publication of WO2009091206A2 publication Critical patent/WO2009091206A2/ko
Publication of WO2009091206A3 publication Critical patent/WO2009091206A3/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1229—Phosphotransferases with a phosphate group as acceptor (2.7.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15—Corynebacterium

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

본 발명은 5'-구아노신 모노포스페이트(5'-guanosine mono-phosphate)를 5'-구아노신 다이포스페이트(5'-guanosine-diphosphate)로 전환하는 구아노신 모노포스페이트 카이네이즈 (guanosine monophosphate kinase)의 활성이 감소된 코리네박테리움 속 미생물 및 이를 이용한 5'-구아노신 모노포스페이트의 생산방법에 관한 것이다.
PCT/KR2009/000238 2008-01-18 2009-01-16 5'-구아노신 모노포스페이트 생산능이 향상된 코리네박테리움 속 미생물 및 이를 이용한 5'-구아노신 모노포스페이트의 생산방법 WO2009091206A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2008-0005645 2008-01-18
KR1020080005645A KR100957689B1 (ko) 2008-01-18 2008-01-18 5'-구아노신 모노포스페이트 생산능이 향상된코리네박테리움 속 미생물 및 이를 이용한 5'-구아노신모노포스페이트의 생산방법

Publications (2)

Publication Number Publication Date
WO2009091206A2 WO2009091206A2 (ko) 2009-07-23
WO2009091206A3 true WO2009091206A3 (ko) 2009-09-24

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/000238 WO2009091206A2 (ko) 2008-01-18 2009-01-16 5'-구아노신 모노포스페이트 생산능이 향상된 코리네박테리움 속 미생물 및 이를 이용한 5'-구아노신 모노포스페이트의 생산방법

Country Status (2)

Country Link
KR (1) KR100957689B1 (ko)
WO (1) WO2009091206A2 (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102259338B1 (ko) * 2021-01-15 2021-06-01 씨제이제일제당 주식회사 신규한 2,5-다이케토-d-글루콘산 리덕타제 변이체 및 이를 이용한 xmp 또는 gmp 생산 방법
KR102259337B1 (ko) * 2021-01-15 2021-06-01 씨제이제일제당 주식회사 신규한 포스포노아세테이트 하이드롤라제 변이체 및 이를 이용한 xmp 또는 gmp 생산 방법
KR102273637B1 (ko) * 2021-01-29 2021-07-06 씨제이제일제당 주식회사 신규한 펩티딜-디펩티다제 변이체 및 이를 이용한 xmp 또는 gmp 생산 방법
KR102273638B1 (ko) * 2021-04-20 2021-07-06 씨제이제일제당 주식회사 신규한 포스포글리세린산 디하이드로게나제 변이체 및 이를 이용한 xmp 또는 gmp 생산 방법
KR102273639B1 (ko) * 2021-04-20 2021-07-06 씨제이제일제당 주식회사 신규한 이중기능성 메틸렌테트라히드로폴레이트 탈수소효소/메테닐테트라하이드로폴레이트 사이클로하이드롤라아제 변이체 및 이를 이용한 xmp 또는 gmp 생산 방법
KR20240086804A (ko) * 2022-12-08 2024-06-19 씨제이제일제당 (주) 퓨린 뉴클레오티드를 생산하는 미생물 및 이를 이용한 퓨린 뉴클레오티드의 생산방법

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030170775A1 (en) * 2000-09-20 2003-09-11 Markus Pompejus Method for modifying the genome of corynebacteria

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030170775A1 (en) * 2000-09-20 2003-09-11 Markus Pompejus Method for modifying the genome of corynebacteria

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
IKEDA M. ET AL.: "The Corynebacterium glutamicum genome: features and impacts on biotechnological processes", APPL. MICROBIOL. BIOTECHNOL., vol. 62, 2003, pages 99 - 109, XP002419971 *
NISHIO Y. ET AL.: "Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermo stability of Corynebacterium efficiens", GENOME RES., vol. 13, no. 7, 2003, pages 1572 - 1579, XP002387831 *
NISHIO Y. ET AL.: "Evolutionary process of amino acid biosynthesis in Corynebacterium at the whole genome level", MOL. BIOL. EVOL., vol. 21, no. 9, 2004, pages 1683 - 1691 *

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Publication number Publication date
KR20090079567A (ko) 2009-07-22
KR100957689B1 (ko) 2010-05-12
WO2009091206A2 (ko) 2009-07-23

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