WO2009088184A3 - 이노신 생산능을 갖는 코리네박테리움속 미생물 및 이를 이용한 이노신의 생산 방법 - Google Patents

이노신 생산능을 갖는 코리네박테리움속 미생물 및 이를 이용한 이노신의 생산 방법 Download PDF

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Publication number
WO2009088184A3
WO2009088184A3 PCT/KR2009/000017 KR2009000017W WO2009088184A3 WO 2009088184 A3 WO2009088184 A3 WO 2009088184A3 KR 2009000017 W KR2009000017 W KR 2009000017W WO 2009088184 A3 WO2009088184 A3 WO 2009088184A3
Authority
WO
WIPO (PCT)
Prior art keywords
inosine
microorganism
ability
genus corynebacterium
produce
Prior art date
Application number
PCT/KR2009/000017
Other languages
English (en)
French (fr)
Other versions
WO2009088184A2 (ko
Inventor
김철하
최종수
김정환
김형석
권중근
안태민
황수연
심재익
백민지
권나라
최혜진
Original Assignee
씨제이제일제당 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 씨제이제일제당 주식회사 filed Critical 씨제이제일제당 주식회사
Priority to US12/811,778 priority Critical patent/US8551736B2/en
Priority to CN2009801040499A priority patent/CN101939413B/zh
Priority to RU2010132638/10A priority patent/RU2469084C2/ru
Priority to JP2010541403A priority patent/JP5377514B2/ja
Priority to BRPI0906487A priority patent/BRPI0906487B1/pt
Priority to MX2010007429A priority patent/MX2010007429A/es
Priority to EP09700802.3A priority patent/EP2233563B1/en
Publication of WO2009088184A2 publication Critical patent/WO2009088184A2/ko
Publication of WO2009088184A3 publication Critical patent/WO2009088184A3/ko

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Classifications

    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02B—BOARDS, SUBSTATIONS OR SWITCHING ARRANGEMENTS FOR THE SUPPLY OR DISTRIBUTION OF ELECTRIC POWER
    • H02B1/00—Frameworks, boards, panels, desks, casings; Details of substations or switching arrangements
    • H02B1/01—Frameworks
    • H02B1/014—Corner connections for frameworks
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2497—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing N- glycosyl compounds (3.2.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/02—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2) hydrolysing N-glycosyl compounds (3.2.2)
    • C12Y302/02001—Purine nucleosidase (3.2.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/02—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2) hydrolysing N-glycosyl compounds (3.2.2)
    • C12Y302/02008—Ribosylpyrimidine nucleosidase (3.2.2.8)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Power Engineering (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Prostheses (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

본 발명은 이노신 분해 경로가 차단되고, 아데닌 누출형 요구성 및 바람직하게는 구아닌 누출형 요구성을 더 갖는 것을 특징으로 하는 이노신 생산능을 갖는 코리네 박테리움숙 미생물 및 상기 미생물을 배양하는 단계를 포함하는, 이노신을 생산하는 방법에 관한 것이다.
PCT/KR2009/000017 2008-01-04 2009-01-02 이노신 생산능을 갖는 코리네박테리움속 미생물 및 이를 이용한 이노신의 생산 방법 WO2009088184A2 (ko)

Priority Applications (7)

Application Number Priority Date Filing Date Title
US12/811,778 US8551736B2 (en) 2008-01-04 2009-01-02 Inosine producing microorganism belonging to the genus Corynebacterium and process of producing inosine using the same
CN2009801040499A CN101939413B (zh) 2008-01-04 2009-01-02 生产肌苷的棒杆菌属微生物及使用其生产肌苷的方法
RU2010132638/10A RU2469084C2 (ru) 2008-01-04 2009-01-02 Штамм микроорганизма corynebacterium ammoniagenes, продуцирующий инозин, и способ получения инозина с его использованием
JP2010541403A JP5377514B2 (ja) 2008-01-04 2009-01-02 イノシン生産能を有するコリネバクテリウム属微生物及びこれを利用したイノシンの生産方法
BRPI0906487A BRPI0906487B1 (pt) 2008-01-04 2009-01-02 microorganismo do gênero corynebacterium com capacidade de produzir inosina e método de produção de inosina
MX2010007429A MX2010007429A (es) 2008-01-04 2009-01-02 Microorganismo del genero corynebacterium que tiene la habilidad de producir inosina y un metodo para producir inosina utilizando el mismo.
EP09700802.3A EP2233563B1 (en) 2008-01-04 2009-01-02 Microorganism of the genus corynebacterium having the ability to produce inosine, and an inosine production method using the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2008-0001441 2008-01-04
KR1020080001441A KR100959662B1 (ko) 2008-01-04 2008-01-04 이노신 생산능을 갖는 코리네박테리움속 미생물 및 이를이용한 이노신의 생산 방법

Publications (2)

Publication Number Publication Date
WO2009088184A2 WO2009088184A2 (ko) 2009-07-16
WO2009088184A3 true WO2009088184A3 (ko) 2009-09-17

Family

ID=40853574

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/000017 WO2009088184A2 (ko) 2008-01-04 2009-01-02 이노신 생산능을 갖는 코리네박테리움속 미생물 및 이를 이용한 이노신의 생산 방법

Country Status (9)

Country Link
US (1) US8551736B2 (ko)
EP (1) EP2233563B1 (ko)
JP (1) JP5377514B2 (ko)
KR (1) KR100959662B1 (ko)
CN (1) CN101939413B (ko)
BR (1) BRPI0906487B1 (ko)
MX (1) MX2010007429A (ko)
RU (1) RU2469084C2 (ko)
WO (1) WO2009088184A2 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2012157699A1 (ja) 2011-05-18 2014-07-31 味の素株式会社 動物用免疫賦活剤、それを含む飼料及びその製造方法
KR101916611B1 (ko) * 2017-12-15 2018-11-07 씨제이제일제당 (주) 신규 폴리펩타이드 및 이를 이용한 imp 생산방법
KR101904675B1 (ko) * 2017-12-15 2018-10-04 씨제이제일제당 (주) 5'-이노신산을 생산하는 미생물 및 이를 이용한 5'-이노신산의 생산 방법

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020053892A (ko) * 2000-12-26 2002-07-06 손 경 식 5'-이노신산을 고수율로 생산하는 미생물 코리네박테리움암모니아게네스 씨제이아이피009 및 그를 이용한5'-이노신산 생산방법
US20040259212A1 (en) * 1999-02-08 2004-12-23 Kyowa Hakko Kogyo Co., Ltd Process for producing purine nucleotides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100397322B1 (ko) * 2000-12-30 2003-09-06 씨제이 주식회사 엘-라이신의 제조방법
KR100505925B1 (ko) * 2002-12-11 2005-08-03 씨제이 주식회사 5’-크산틸산을 생산하는 미생물
KR100882418B1 (ko) * 2007-01-15 2009-02-05 씨제이제일제당 (주) 이노신을 생산하는 미생물 및 그를 이용한 이노신 제조방법

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040259212A1 (en) * 1999-02-08 2004-12-23 Kyowa Hakko Kogyo Co., Ltd Process for producing purine nucleotides
KR20020053892A (ko) * 2000-12-26 2002-07-06 손 경 식 5'-이노신산을 고수율로 생산하는 미생물 코리네박테리움암모니아게네스 씨제이아이피009 및 그를 이용한5'-이노신산 생산방법

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE NCBI 2006, "Corynebacterium ammoniagenes strain ATCC 6872 ribonucleoside hydrolase 1 (rihl) gene, complete cds.", XP008137690, Database accession no. AY603363 *
DATABASE NCBI 2006, "Corynebacterium ammoniagenes strain ATCC 6872 ribonucleoside hydrolase 2 (rih2) gene, complete cds.", XP008137692, Database accession no. AY603360 *
HYUN-SOO KIM ET AL.: "Genes encoding ribonucleoside hydrolase 1 and 2 from Corynebacterium ammoniagenes", MICROBIOLOGY, vol. 152, 2006, pages 1169 - 1177, XP008110242 *
See also references of EP2233563A4 *

Also Published As

Publication number Publication date
JP5377514B2 (ja) 2013-12-25
KR20090075548A (ko) 2009-07-08
EP2233563A4 (en) 2011-08-17
KR100959662B1 (ko) 2010-05-26
EP2233563B1 (en) 2013-11-13
CN101939413A (zh) 2011-01-05
CN101939413B (zh) 2012-06-13
RU2469084C2 (ru) 2012-12-10
JP2011508599A (ja) 2011-03-17
US20110003342A1 (en) 2011-01-06
BRPI0906487B1 (pt) 2018-11-13
EP2233563A2 (en) 2010-09-29
WO2009088184A2 (ko) 2009-07-16
US8551736B2 (en) 2013-10-08
BRPI0906487A2 (pt) 2015-08-04
RU2010132638A (ru) 2012-02-10
MX2010007429A (es) 2010-11-30

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