WO2009044816A1 - 生体適合性および低摩耗性部材及びそれを用いた人工関節並びにその製造方法 - Google Patents

生体適合性および低摩耗性部材及びそれを用いた人工関節並びにその製造方法 Download PDF

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Publication number
WO2009044816A1
WO2009044816A1 PCT/JP2008/067941 JP2008067941W WO2009044816A1 WO 2009044816 A1 WO2009044816 A1 WO 2009044816A1 JP 2008067941 W JP2008067941 W JP 2008067941W WO 2009044816 A1 WO2009044816 A1 WO 2009044816A1
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WO
WIPO (PCT)
Prior art keywords
same
biocompatible
base material
producing
artificial joint
Prior art date
Application number
PCT/JP2008/067941
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English (en)
French (fr)
Inventor
Masayuki Kyomoto
Kazuhiko Ishihara
Kozo Nakamura
Yoshio Takatori
Hiroshi Kawaguchi
Toru Moro
Original Assignee
Japan Medical Materials Corporation
The University Of Tokyo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Medical Materials Corporation, The University Of Tokyo filed Critical Japan Medical Materials Corporation
Priority to EP08836671.1A priority Critical patent/EP2204197B1/en
Priority to US12/733,976 priority patent/US9192694B2/en
Priority to JP2009536083A priority patent/JP5918924B2/ja
Publication of WO2009044816A1 publication Critical patent/WO2009044816A1/ja

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/32—Joints for the hip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
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    • A—HUMAN NECESSITIES
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
    • A61F2002/30026—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis differing in wear resistance
    • A—HUMAN NECESSITIES
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
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    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006—Properties of materials and coating materials
    • A61F2002/30065—Properties of materials and coating materials thermoplastic, i.e. softening or fusing when heated, and hardening and becoming rigid again when cooled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2002/30673—Lubricating means, e.g. synovial pocket
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    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30682—Means for preventing migration of particles released by the joint, e.g. wear debris or cement particles
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    • A—HUMAN NECESSITIES
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    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
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    • A—HUMAN NECESSITIES
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    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
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    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/00976—Coating or prosthesis-covering structure made of proteins or of polypeptides, e.g. of bone morphogenic proteins BMP or of transforming growth factors TGF
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    • A61L2400/00—Materials characterised by their function or physical properties
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    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

　本発明は、摺動部位の摩擦を抑えて、摩耗粉の発生を抑制することができ、また、生体内で、十分な機械的特性を維持することができる摺動部材、人工関節及びその製造方法を提供すること。水酸基を形成可能な基材１と、基材１の適宜部所に積層された生体適合材料層４と、を設け、基材１には、その表面の少なくとも所要箇所に表面処理によって水酸基を形成して表面処理層２を設ける一方、生体適合材料層４は、ホスホリルコリン基を含むポリマーから構成し、基材１と生体適合材料層４とを、上記水酸基と共有結合する一方上記生体適合材料とも共有結合するシリカからなる接着層３を介して接合させる。
PCT/JP2008/067941 2007-10-03 2008-10-02 生体適合性および低摩耗性部材及びそれを用いた人工関節並びにその製造方法 WO2009044816A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP08836671.1A EP2204197B1 (en) 2007-10-03 2008-10-02 Biocompatible and low-wear material, artificial joint using the same and method of producing the same
US12/733,976 US9192694B2 (en) 2007-10-03 2008-10-02 Biocompatible and low-abrasion member, and artificial joint using the same and method of producing the same
JP2009536083A JP5918924B2 (ja) 2007-10-03 2008-10-02 生体適合性および低摩耗性摺動部材の製造方法

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2007260191 2007-10-03
JP2007-260191 2007-10-03
JP2008012794 2008-01-23
JP2008-012794 2008-01-23

Publications (1)

Publication Number Publication Date
WO2009044816A1 true WO2009044816A1 (ja) 2009-04-09

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PCT/JP2008/067941 WO2009044816A1 (ja) 2007-10-03 2008-10-02 生体適合性および低摩耗性部材及びそれを用いた人工関節並びにその製造方法

Country Status (4)

Country Link
US (1) US9192694B2 (ja)
EP (1) EP2204197B1 (ja)
JP (1) JP5918924B2 (ja)
WO (1) WO2009044816A1 (ja)

Cited By (9)

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WO2010074238A1 (ja) * 2008-12-25 2010-07-01 日本メディカルマテリアル株式会社 ポリマー摺動材料、人工関節部材、医療器具及びその製造方法
JP2013013862A (ja) * 2011-07-05 2013-01-24 Iwatani Internatl Corp 有機性排水浄化処理用生物ろ過材
WO2013180228A1 (ja) * 2012-05-31 2013-12-05 京セラメディカル株式会社 摺動材料およびその製造方法
JP2014004352A (ja) * 2012-05-31 2014-01-16 Kyocera Medical Corp 摺動材料およびその製造方法
JP2014124502A (ja) * 2012-12-27 2014-07-07 Kyocera Medical Corp 人工関節用摺動部材の製造方法および人工関節用摺動部材
JP2014166229A (ja) * 2013-02-28 2014-09-11 Kyocera Medical Corp 摺動材料およびその製造方法
WO2017002223A1 (ja) * 2015-07-01 2017-01-05 株式会社ナントー インプラント、フィクスチャー、アバットメント、基端側骨コンポーネント、先端側骨コンポーネント
CN106474568A (zh) * 2015-08-27 2017-03-08 住友橡胶工业株式会社 表面改性金属及金属表面的改性方法
JP2019158247A (ja) * 2018-03-14 2019-09-19 株式会社デンソー 熱交換器

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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CN113995886B (zh) * 2021-10-28 2023-05-16 苏州微创关节医疗科技有限公司 人工关节构件及其制备方法和摩擦副

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003310649A (ja) * 2002-02-19 2003-11-05 Kobe Steel Ltd 高分子材料製人工関節部材
JP2004502514A (ja) * 2000-07-10 2004-01-29 エピオン　コーポレイション Ｇｃｉｂによる人工股関節の改善
JP2005524772A (ja) * 2002-04-29 2005-08-18 エーディー．サーフ．イーエヌジー．リミテッド プラズマ浸炭を用いたコバルト−クロミウム系合金の表面処理方法
WO2005097673A1 (ja) * 2004-03-30 2005-10-20 Toyo Advanced Technologies Co., Ltd. 基材の表面処理方法及び表面処理された基材、医療用材料、医療用器具
JP2006000219A (ja) * 2004-06-15 2006-01-05 Mizuho Co Ltd 人工関節用インプラント
JP2006089778A (ja) * 2004-09-21 2006-04-06 Japan Science & Technology Agency 官能基導入無機化合物およびその製造方法、複合体およびその製造方法、医療用材料
JP2007031408A (ja) * 2005-07-29 2007-02-08 Kanagawa Acad Of Sci & Technol 生理活性物質固定化チタン材及びその製造方法
JP2007505697A (ja) * 2003-09-15 2007-03-15 ウィックストローム、エリック シリル化治療剤を結合したインプラント
JP2007195883A (ja) * 2006-01-30 2007-08-09 Toyo Advanced Technologies Co Ltd ステント及びその製造方法
JP2007202965A (ja) * 2006-02-06 2007-08-16 Japan Medical Materials Corp 低摩耗性摺動部材及びそれを用いた人工関節
WO2007091521A1 (ja) * 2006-02-06 2007-08-16 Japan Medical Materials Corporation 低摩耗性摺動部材及びそれを用いた人工関節

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE486619T1 (de) 2002-02-19 2010-11-15 Kobe Steel Ltd Künstliches gelenkglied aus einem polymeren material
KR101051674B1 (ko) * 2002-11-25 2011-07-26 가부시키가이샤 시세이도 소재의 표면 개질 방법
US20070054127A1 (en) * 2005-08-26 2007-03-08 Hergenrother Robert W Silane coating compositions, coating systems, and methods
US20070299511A1 (en) * 2006-06-27 2007-12-27 Gale David C Thin stent coating
WO2008006911A1 (en) * 2006-07-14 2008-01-17 Biocompatibles Uk Limited Coated implant
US8084077B2 (en) * 2007-05-25 2011-12-27 Abbott Laboratories One-step phosphorylcholine-linked polymer coating and drug loading of stent

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004502514A (ja) * 2000-07-10 2004-01-29 エピオン　コーポレイション Ｇｃｉｂによる人工股関節の改善
JP2003310649A (ja) * 2002-02-19 2003-11-05 Kobe Steel Ltd 高分子材料製人工関節部材
JP2005524772A (ja) * 2002-04-29 2005-08-18 エーディー．サーフ．イーエヌジー．リミテッド プラズマ浸炭を用いたコバルト−クロミウム系合金の表面処理方法
JP2007505697A (ja) * 2003-09-15 2007-03-15 ウィックストローム、エリック シリル化治療剤を結合したインプラント
WO2005097673A1 (ja) * 2004-03-30 2005-10-20 Toyo Advanced Technologies Co., Ltd. 基材の表面処理方法及び表面処理された基材、医療用材料、医療用器具
JP2006000219A (ja) * 2004-06-15 2006-01-05 Mizuho Co Ltd 人工関節用インプラント
JP2006089778A (ja) * 2004-09-21 2006-04-06 Japan Science & Technology Agency 官能基導入無機化合物およびその製造方法、複合体およびその製造方法、医療用材料
JP2007031408A (ja) * 2005-07-29 2007-02-08 Kanagawa Acad Of Sci & Technol 生理活性物質固定化チタン材及びその製造方法
JP2007195883A (ja) * 2006-01-30 2007-08-09 Toyo Advanced Technologies Co Ltd ステント及びその製造方法
JP2007202965A (ja) * 2006-02-06 2007-08-16 Japan Medical Materials Corp 低摩耗性摺動部材及びそれを用いた人工関節
WO2007091521A1 (ja) * 2006-02-06 2007-08-16 Japan Medical Materials Corporation 低摩耗性摺動部材及びそれを用いた人工関節

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2204197A4 *

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8765265B2 (en) 2008-12-25 2014-07-01 Kyocera Medical Corporation Polymer sliding material, artificial joint member, medical appliance, and manufacturing method therefor
WO2010074238A1 (ja) * 2008-12-25 2010-07-01 日本メディカルマテリアル株式会社 ポリマー摺動材料、人工関節部材、医療器具及びその製造方法
JP2013013862A (ja) * 2011-07-05 2013-01-24 Iwatani Internatl Corp 有機性排水浄化処理用生物ろ過材
US9700651B2 (en) 2012-05-31 2017-07-11 Kyocera Medical Corporation Bearing material and method of producing the same
WO2013180228A1 (ja) * 2012-05-31 2013-12-05 京セラメディカル株式会社 摺動材料およびその製造方法
JP2014004352A (ja) * 2012-05-31 2014-01-16 Kyocera Medical Corp 摺動材料およびその製造方法
CN104349744A (zh) * 2012-05-31 2015-02-11 京瓷医疗株式会社 滑动材料及其制造方法
JP2014124502A (ja) * 2012-12-27 2014-07-07 Kyocera Medical Corp 人工関節用摺動部材の製造方法および人工関節用摺動部材
JP2014166229A (ja) * 2013-02-28 2014-09-11 Kyocera Medical Corp 摺動材料およびその製造方法
WO2017002223A1 (ja) * 2015-07-01 2017-01-05 株式会社ナントー インプラント、フィクスチャー、アバットメント、基端側骨コンポーネント、先端側骨コンポーネント
CN106474568A (zh) * 2015-08-27 2017-03-08 住友橡胶工业株式会社 表面改性金属及金属表面的改性方法
CN106474568B (zh) * 2015-08-27 2021-04-30 住友橡胶工业株式会社 表面改性金属及金属表面的改性方法
JP2019158247A (ja) * 2018-03-14 2019-09-19 株式会社デンソー 熱交換器

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