WO2009041515A1 - 骨吸収抑制剤、並びにこれを含有する飲料、食品及び医薬品 - Google Patents
骨吸収抑制剤、並びにこれを含有する飲料、食品及び医薬品 Download PDFInfo
- Publication number
- WO2009041515A1 WO2009041515A1 PCT/JP2008/067319 JP2008067319W WO2009041515A1 WO 2009041515 A1 WO2009041515 A1 WO 2009041515A1 JP 2008067319 W JP2008067319 W JP 2008067319W WO 2009041515 A1 WO2009041515 A1 WO 2009041515A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- bone resorption
- resorption inhibitor
- barley
- drink
- food
- Prior art date
Links
- 229940078581 Bone resorption inhibitor Drugs 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title abstract 2
- 235000013305 food Nutrition 0.000 title abstract 2
- 229940069780 barley extract Drugs 0.000 abstract 3
- 241000209219 Hordeum Species 0.000 abstract 2
- 235000007340 Hordeum vulgare Nutrition 0.000 abstract 2
- 208000020084 Bone disease Diseases 0.000 abstract 1
- 102000004171 Cathepsin K Human genes 0.000 abstract 1
- 108090000625 Cathepsin K Proteins 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000007853 buffer solution Substances 0.000 abstract 1
- 235000013312 flour Nutrition 0.000 abstract 1
- 230000035876 healing Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8998—Hordeum (barley)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Physical Education & Sports Medicine (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
本発明は、大麦を粉砕した大麦粉を水若しくは緩衝液で抽出した大麦抽出物又はこれを分画した画分或いは前記大麦抽出物又は前記画分の酵素処理物、を有効成分として含有する骨吸収抑制剤を提供する。本発明によれば、人体への安全性に優れ、医薬品のみならず食品への応用も可能な、カテプシンK阻害剤とは異なるメカニズムの骨吸収抑制剤であって、骨粗鬆症、慢性関節リウマチを始めとする骨疾患の予防及び改善(治療、症状緩和)を可能とする骨吸収抑制剤が提供される。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009534368A JP5307019B2 (ja) | 2007-09-27 | 2008-09-25 | 骨吸収抑制剤、並びにこれを含有する飲料、食品及び医薬品 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007-252110 | 2007-09-27 | ||
JP2007252110 | 2007-09-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2009041515A1 true WO2009041515A1 (ja) | 2009-04-02 |
Family
ID=40511397
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/067319 WO2009041515A1 (ja) | 2007-09-27 | 2008-09-25 | 骨吸収抑制剤、並びにこれを含有する飲料、食品及び医薬品 |
Country Status (2)
Country | Link |
---|---|
JP (1) | JP5307019B2 (ja) |
WO (1) | WO2009041515A1 (ja) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2014214104A (ja) * | 2013-04-24 | 2014-11-17 | 株式会社日清製粉グループ本社 | 非酵素的糖化反応抑制剤 |
JP2016169203A (ja) * | 2015-03-09 | 2016-09-23 | 株式会社東洋新薬 | カルシウム吸収促進剤 |
US11324795B2 (en) * | 2013-11-25 | 2022-05-10 | University-Industry Cooperation Group Of Kyung Hee University | Composition comprising Hordeum vulgare extract for preventing or treating short stature |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101505945B1 (ko) * | 2013-10-22 | 2015-03-25 | 롯데칠성음료주식회사 | 풍미가 개선된 기능성 음료 |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0474127A (ja) * | 1990-07-16 | 1992-03-09 | Takada Seiyaku Kk | 血圧降下作用を有する大豆煮汁抽出物 |
JP2002142723A (ja) * | 2000-11-13 | 2002-05-21 | Japan Natural Laboratory Co Ltd | ダイエット加工食品用原料およびダイエット加工食品 |
WO2004002978A1 (ja) * | 2002-06-26 | 2004-01-08 | Suntory Limited | 消化管運動促進飲食物 |
JP2004051519A (ja) * | 2002-07-18 | 2004-02-19 | Kikkoman Corp | アンジオテンシン変換酵素阻害剤及びその製造法 |
JP2005139150A (ja) * | 2003-11-10 | 2005-06-02 | Api Co Ltd | エストロゲン様作用剤及びその製造方法、並びに骨粗しょう症予防剤及び飲食品 |
CN1679767A (zh) * | 2005-02-05 | 2005-10-12 | 上海中医药大学附属曙光医院 | 一种防治骨质疏松症的药物制剂及其制备方法 |
JP2006151843A (ja) * | 2004-11-26 | 2006-06-15 | Shimada Kagaku Kogyo Kk | カテプシンk阻害剤およびその機能が付与された食品 |
JP2007015941A (ja) * | 2005-07-05 | 2007-01-25 | Takahito Tokuyama | 米を除く穀類及び豆類を原料とする寿命延長剤 |
-
2008
- 2008-09-25 JP JP2009534368A patent/JP5307019B2/ja not_active Expired - Fee Related
- 2008-09-25 WO PCT/JP2008/067319 patent/WO2009041515A1/ja active Application Filing
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0474127A (ja) * | 1990-07-16 | 1992-03-09 | Takada Seiyaku Kk | 血圧降下作用を有する大豆煮汁抽出物 |
JP2002142723A (ja) * | 2000-11-13 | 2002-05-21 | Japan Natural Laboratory Co Ltd | ダイエット加工食品用原料およびダイエット加工食品 |
WO2004002978A1 (ja) * | 2002-06-26 | 2004-01-08 | Suntory Limited | 消化管運動促進飲食物 |
JP2004051519A (ja) * | 2002-07-18 | 2004-02-19 | Kikkoman Corp | アンジオテンシン変換酵素阻害剤及びその製造法 |
JP2005139150A (ja) * | 2003-11-10 | 2005-06-02 | Api Co Ltd | エストロゲン様作用剤及びその製造方法、並びに骨粗しょう症予防剤及び飲食品 |
JP2006151843A (ja) * | 2004-11-26 | 2006-06-15 | Shimada Kagaku Kogyo Kk | カテプシンk阻害剤およびその機能が付与された食品 |
CN1679767A (zh) * | 2005-02-05 | 2005-10-12 | 上海中医药大学附属曙光医院 | 一种防治骨质疏松症的药物制剂及其制备方法 |
JP2007015941A (ja) * | 2005-07-05 | 2007-01-25 | Takahito Tokuyama | 米を除く穀類及び豆類を原料とする寿命延長剤 |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2014214104A (ja) * | 2013-04-24 | 2014-11-17 | 株式会社日清製粉グループ本社 | 非酵素的糖化反応抑制剤 |
US11324795B2 (en) * | 2013-11-25 | 2022-05-10 | University-Industry Cooperation Group Of Kyung Hee University | Composition comprising Hordeum vulgare extract for preventing or treating short stature |
JP2016169203A (ja) * | 2015-03-09 | 2016-09-23 | 株式会社東洋新薬 | カルシウム吸収促進剤 |
Also Published As
Publication number | Publication date |
---|---|
JPWO2009041515A1 (ja) | 2011-01-27 |
JP5307019B2 (ja) | 2013-10-02 |
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