WO2009028649A1 - アミノ酸高含量固形製剤の低容量化製法 - Google Patents
アミノ酸高含量固形製剤の低容量化製法 Download PDFInfo
- Publication number
- WO2009028649A1 WO2009028649A1 PCT/JP2008/065500 JP2008065500W WO2009028649A1 WO 2009028649 A1 WO2009028649 A1 WO 2009028649A1 JP 2008065500 W JP2008065500 W JP 2008065500W WO 2009028649 A1 WO2009028649 A1 WO 2009028649A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- amino acid
- solid preparation
- volume
- acid content
- reduction
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
- A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
Abstract
1回の摂取量が増大しつつあるアミノ酸製剤のさらなる低容量化方法および製剤の提供。 アミノ酸を有効成分とする固形製剤の製造方法であって、アミノ酸を含有する粉体および結合剤を容器に収容し、当該容器内で一工程で混練および造粒する工程を含む製造方法、ならびに前記製造方法により製造されるアミノ酸高含量固形製剤。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009530195A JP5454142B2 (ja) | 2007-08-31 | 2008-08-29 | アミノ酸高含量固形製剤の低容量化製法 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007225585 | 2007-08-31 | ||
JP2007-225585 | 2007-08-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2009028649A1 true WO2009028649A1 (ja) | 2009-03-05 |
Family
ID=40387360
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/065500 WO2009028649A1 (ja) | 2007-08-31 | 2008-08-29 | アミノ酸高含量固形製剤の低容量化製法 |
Country Status (2)
Country | Link |
---|---|
JP (1) | JP5454142B2 (ja) |
WO (1) | WO2009028649A1 (ja) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013193974A (ja) * | 2012-03-19 | 2013-09-30 | Fancl Corp | アミノ酸高含有錠剤 |
JP2013223483A (ja) * | 2012-03-19 | 2013-10-31 | Fancl Corp | 高分岐環状構造を持つデキストリンを含有するアミノ酸高含有錠剤 |
CN105249133A (zh) * | 2015-10-27 | 2016-01-20 | 无锡金维氨生物科技有限公司 | 一种支链氨基酸添加剂 |
EP2719290B1 (en) * | 2012-10-12 | 2017-03-22 | Innobio Limited | A microencapsulated amino acid composition and method of manufacturing microencapsulated amino acid composition |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09278534A (ja) * | 1996-04-05 | 1997-10-28 | Matsushita Electric Ind Co Ltd | セラミック顆粒の製造方法 |
JP2003212768A (ja) * | 2002-01-24 | 2003-07-30 | Ajinomoto Co Inc | 分岐鎖アミノ酸含有顆粒の製造方法 |
JP2004081010A (ja) * | 2002-08-22 | 2004-03-18 | Fancl Corp | 食品組成物 |
WO2006085677A1 (en) * | 2005-02-09 | 2006-08-17 | Shinagawa Machinery Works Co., Ltd | Kneading and granulating machine |
-
2008
- 2008-08-29 JP JP2009530195A patent/JP5454142B2/ja active Active
- 2008-08-29 WO PCT/JP2008/065500 patent/WO2009028649A1/ja active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09278534A (ja) * | 1996-04-05 | 1997-10-28 | Matsushita Electric Ind Co Ltd | セラミック顆粒の製造方法 |
JP2003212768A (ja) * | 2002-01-24 | 2003-07-30 | Ajinomoto Co Inc | 分岐鎖アミノ酸含有顆粒の製造方法 |
JP2004081010A (ja) * | 2002-08-22 | 2004-03-18 | Fancl Corp | 食品組成物 |
WO2006085677A1 (en) * | 2005-02-09 | 2006-08-17 | Shinagawa Machinery Works Co., Ltd | Kneading and granulating machine |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013193974A (ja) * | 2012-03-19 | 2013-09-30 | Fancl Corp | アミノ酸高含有錠剤 |
JP2013223483A (ja) * | 2012-03-19 | 2013-10-31 | Fancl Corp | 高分岐環状構造を持つデキストリンを含有するアミノ酸高含有錠剤 |
EP2719290B1 (en) * | 2012-10-12 | 2017-03-22 | Innobio Limited | A microencapsulated amino acid composition and method of manufacturing microencapsulated amino acid composition |
CN105249133A (zh) * | 2015-10-27 | 2016-01-20 | 无锡金维氨生物科技有限公司 | 一种支链氨基酸添加剂 |
Also Published As
Publication number | Publication date |
---|---|
JPWO2009028649A1 (ja) | 2010-12-02 |
JP5454142B2 (ja) | 2014-03-26 |
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