WO2009007334A3 - Transdermal therapeutic systems which contain the substance anastrozole - Google Patents
Transdermal therapeutic systems which contain the substance anastrozole Download PDFInfo
- Publication number
- WO2009007334A3 WO2009007334A3 PCT/EP2008/058743 EP2008058743W WO2009007334A3 WO 2009007334 A3 WO2009007334 A3 WO 2009007334A3 EP 2008058743 W EP2008058743 W EP 2008058743W WO 2009007334 A3 WO2009007334 A3 WO 2009007334A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- substance
- anastrozole
- transdermal therapeutic
- contain
- layer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to a transdermal therapeutic system (TTS) which comprises a back layer impermeable to the substance, an adhesive layer (layer holding the substance) which contains an adhesive component and the substance anastrozole or the physiologically acceptable hydrate thereof, solvate or salt dissolved in a concentration of 0.1% (m/m) to 30% (m/m), relative to the weight of the adhesive layer, and a removable layer in contact with the skin which is removed before application of the TTS. The invention likewise relates to the use of said TTS.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08774817A EP2178523A2 (en) | 2007-07-10 | 2008-07-07 | Transdermal therapeutic systems which contain the substance anastrozole |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE200710032468 DE102007032468A1 (en) | 2007-07-10 | 2007-07-10 | Transdermal therapeutic systems containing the active substance anastrozole |
DE102007032468.7 | 2007-07-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009007334A2 WO2009007334A2 (en) | 2009-01-15 |
WO2009007334A3 true WO2009007334A3 (en) | 2009-03-12 |
Family
ID=40121449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2008/058743 WO2009007334A2 (en) | 2007-07-10 | 2008-07-07 | Transdermal therapeutic systems which contain the substance anastrozole |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2178523A2 (en) |
DE (1) | DE102007032468A1 (en) |
WO (1) | WO2009007334A2 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102010046464A1 (en) | 2009-03-19 | 2011-04-21 | Amw Gmbh | Transdermal system, useful for indicating breast cancer in postmenopausal women, comprises aromatase inhibitor, drug-impermeable skin protective layer, reservoir, optional drug-permeable membrane and a carrier for reservoir or membrane |
DE102010026883A1 (en) | 2010-03-11 | 2011-12-15 | Amw Gmbh | Transdermal system useful e.g. for indication of breast cancer with progesterone-receptor positive status, comprises e.g. aromatase inhibitor, active substance puller protection layer, active substance reservoir |
WO2017054151A1 (en) * | 2015-09-30 | 2017-04-06 | 徐静 | Patch for external application containing anastrozole and use thereof |
DE102019110398A1 (en) * | 2019-04-18 | 2020-10-22 | Amw Gmbh | Transdermal delivery system with aromatase inhibitor |
DE102019110397A1 (en) * | 2019-04-18 | 2020-10-22 | Amw Gmbh | Transdermal delivery system with aromatase inhibitor in a supersaturated matrix |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997006788A1 (en) * | 1995-08-14 | 1997-02-27 | Janssen Pharmaceutica N.V. | Transdermal administration of vorozole |
WO2002017928A2 (en) * | 2000-08-30 | 2002-03-07 | Lts Lohman Therapie-Systeme Ag | Transdermal therapeutic system for releasing exemestane |
CN1927190A (en) * | 2006-09-28 | 2007-03-14 | 哈尔滨健迪医药技术有限公司 | Letrozole transdermal drug administration plaster and its preparation method |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE505635C2 (en) | 1995-11-28 | 1997-09-22 | Aga Ab | Method and apparatus for adding an odorant to a gas piping system |
AUPN814496A0 (en) | 1996-02-19 | 1996-03-14 | Monash University | Dermal penetration enhancer |
EP0943333A1 (en) | 1998-03-18 | 1999-09-22 | S.W. Patentverwertungs GmbH | Medicament for the prevention and/or treatment of breast cancer comprising an inhibitor of estrogen synthesis |
US6476079B1 (en) * | 1999-12-23 | 2002-11-05 | Leiras Oy | Devices for the delivery of drugs having antiprogestinic properties |
AU2001262378A1 (en) * | 2000-07-10 | 2002-02-13 | Hormos Medical Corporation | Method for treating cryptorchidism |
ES2299730T3 (en) * | 2002-07-12 | 2008-06-01 | Pantarhei Bioscience B.V. | PHARMACEUTICAL COMPOSITION THAT INCLUDES STETROL DERIVATIVES FOR USE IN CANCER THERAPY. |
US20060189670A1 (en) * | 2005-02-22 | 2006-08-24 | Glenmark Pharmaceuticals Limited | Process for the preparation of anastrozole and intermediates thereof |
US20090215731A1 (en) * | 2005-10-19 | 2009-08-27 | Chavah Pty Ltd. | Reduction of Side Effects From Aromatase Inhibitors Used for Treating Breast Cancer |
-
2007
- 2007-07-10 DE DE200710032468 patent/DE102007032468A1/en not_active Ceased
-
2008
- 2008-07-07 EP EP08774817A patent/EP2178523A2/en not_active Withdrawn
- 2008-07-07 WO PCT/EP2008/058743 patent/WO2009007334A2/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997006788A1 (en) * | 1995-08-14 | 1997-02-27 | Janssen Pharmaceutica N.V. | Transdermal administration of vorozole |
WO2002017928A2 (en) * | 2000-08-30 | 2002-03-07 | Lts Lohman Therapie-Systeme Ag | Transdermal therapeutic system for releasing exemestane |
CN1927190A (en) * | 2006-09-28 | 2007-03-14 | 哈尔滨健迪医药技术有限公司 | Letrozole transdermal drug administration plaster and its preparation method |
Non-Patent Citations (3)
Title |
---|
BUZDAR AMAN U; ROBERTSON JOHN F R; EIERMANN WOLFGANG; NABHOLTZ JEAN-MARC: "An overview of the pharmacology and pharmacokinetics of the newer generation aromatase inhibitors anastrozole, letrozole, and exemestane.", CANCER, vol. 95, no. 9, 1 November 2002 (2002-11-01), United States, pages 2006 - 2016, XP002510617 * |
DATABASE EPODOC EUROPEAN PATENT OFFICE, THE HAGUE, NL; XP002510618 * |
SIPE ET AL: "A prospective randomized trial comparing anastrozole and clomiphene citrate in an ovulation induction protocol using gonadotropins", FERTILITY AND STERILITY, ELSEVIER SCIENCE INC, NEW YORK, NY, US, vol. 86, no. 6, 22 November 2006 (2006-11-22), pages 1676 - 1681, XP005776229, ISSN: 0015-0282 * |
Also Published As
Publication number | Publication date |
---|---|
DE102007032468A1 (en) | 2009-01-15 |
EP2178523A2 (en) | 2010-04-28 |
WO2009007334A2 (en) | 2009-01-15 |
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