WO2002017928A3 - Transdermal therapeutic system for releasing exemestane - Google Patents

Transdermal therapeutic system for releasing exemestane Download PDF

Info

Publication number
WO2002017928A3
WO2002017928A3 PCT/EP2001/009530 EP0109530W WO0217928A3 WO 2002017928 A3 WO2002017928 A3 WO 2002017928A3 EP 0109530 W EP0109530 W EP 0109530W WO 0217928 A3 WO0217928 A3 WO 0217928A3
Authority
WO
WIPO (PCT)
Prior art keywords
active agent
exemestane
transdermal therapeutic
therapeutic system
releasing
Prior art date
Application number
PCT/EP2001/009530
Other languages
German (de)
French (fr)
Other versions
WO2002017928A2 (en
Inventor
Thorsten Selzer
Original Assignee
Lts Lohman Therapie Systeme Ag
Thorsten Selzer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lts Lohman Therapie Systeme Ag, Thorsten Selzer filed Critical Lts Lohman Therapie Systeme Ag
Publication of WO2002017928A2 publication Critical patent/WO2002017928A2/en
Publication of WO2002017928A3 publication Critical patent/WO2002017928A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a transdermal therapeutic system in the form of a plaster, for administering the active agent exemestane or another active agent from the group of aromatase inhibitors. The inventive system has a back layer which is impermeable to the active agent, an active agent reservoir which is connected to said back layer and which contains the active agent exemestane and/or another active agent from the group of aromatase inhibitors, an adhesive layer on the skin side and a protective layer which is impermeable to the active agent and which can be removed prior to application.
PCT/EP2001/009530 2000-08-30 2001-08-18 Transdermal therapeutic system for releasing exemestane WO2002017928A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10042411.2 2000-08-30
DE2000142411 DE10042411A1 (en) 2000-08-30 2000-08-30 Transdermal therapeutic system for the delivery of exemestane

Publications (2)

Publication Number Publication Date
WO2002017928A2 WO2002017928A2 (en) 2002-03-07
WO2002017928A3 true WO2002017928A3 (en) 2002-06-27

Family

ID=7654181

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/009530 WO2002017928A2 (en) 2000-08-30 2001-08-18 Transdermal therapeutic system for releasing exemestane

Country Status (2)

Country Link
DE (1) DE10042411A1 (en)
WO (1) WO2002017928A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007032468A1 (en) * 2007-07-10 2009-01-15 Brätter, Christian, Dr. Transdermal therapeutic systems containing the active substance anastrozole
HU227970B1 (en) 2007-07-10 2012-07-30 Egis Gyogyszergyar Nyrt Pharmaceutical compositions containing silicones of high volatility
DE102010046464A1 (en) 2009-03-19 2011-04-21 Amw Gmbh Transdermal system, useful for indicating breast cancer in postmenopausal women, comprises aromatase inhibitor, drug-impermeable skin protective layer, reservoir, optional drug-permeable membrane and a carrier for reservoir or membrane
DE102010026883A1 (en) 2010-03-11 2011-12-15 Amw Gmbh Transdermal system useful e.g. for indication of breast cancer with progesterone-receptor positive status, comprises e.g. aromatase inhibitor, active substance puller protection layer, active substance reservoir
US11154535B2 (en) 2012-07-31 2021-10-26 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
US10045935B2 (en) 2012-07-31 2018-08-14 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
DE102019201431A1 (en) 2019-02-05 2020-08-06 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system (TTS) with solids reservoir
DE102019201430A1 (en) 2019-02-05 2020-08-06 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system (TTS) with transport medium
DE102019110397A1 (en) * 2019-04-18 2020-10-22 Amw Gmbh Transdermal delivery system with aromatase inhibitor in a supersaturated matrix
DE102019110398A1 (en) * 2019-04-18 2020-10-22 Amw Gmbh Transdermal delivery system with aromatase inhibitor

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993019746A1 (en) * 1992-04-03 1993-10-14 Orion-Yhtymä Oy Topical administration of toremifene and its metabolites
WO1997006788A1 (en) * 1995-08-14 1997-02-27 Janssen Pharmaceutica N.V. Transdermal administration of vorozole
WO1997029735A1 (en) * 1996-02-19 1997-08-21 Monash University Dermal penetration enhancers and drug delivery systems involving same
EP0943333A1 (en) * 1998-03-18 1999-09-22 S.W. Patentverwertungs GmbH Medicament for the prevention and/or treatment of breast cancer comprising an inhibitor of estrogen synthesis
WO2000043553A1 (en) * 1999-01-26 2000-07-27 Pro-Duct Health, Inc. Identifying, monitoring, and treating women for breast precancer or cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9212833D0 (en) * 1992-06-17 1992-07-29 Glaxo Group Ltd Chemical compounds
US5567831A (en) * 1995-08-16 1996-10-22 Duguesne University Of The Holy Ghost Non-steroidal sulfatase inhibitor compounds and their method of use

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993019746A1 (en) * 1992-04-03 1993-10-14 Orion-Yhtymä Oy Topical administration of toremifene and its metabolites
WO1997006788A1 (en) * 1995-08-14 1997-02-27 Janssen Pharmaceutica N.V. Transdermal administration of vorozole
WO1997029735A1 (en) * 1996-02-19 1997-08-21 Monash University Dermal penetration enhancers and drug delivery systems involving same
EP0943333A1 (en) * 1998-03-18 1999-09-22 S.W. Patentverwertungs GmbH Medicament for the prevention and/or treatment of breast cancer comprising an inhibitor of estrogen synthesis
WO2000043553A1 (en) * 1999-01-26 2000-07-27 Pro-Duct Health, Inc. Identifying, monitoring, and treating women for breast precancer or cancer

Also Published As

Publication number Publication date
WO2002017928A2 (en) 2002-03-07
DE10042411A1 (en) 2002-03-28

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