WO2009000425A2 - Système de vérification de l'intégrité d'un emballage sous blister - Google Patents
Système de vérification de l'intégrité d'un emballage sous blister Download PDFInfo
- Publication number
- WO2009000425A2 WO2009000425A2 PCT/EP2008/004710 EP2008004710W WO2009000425A2 WO 2009000425 A2 WO2009000425 A2 WO 2009000425A2 EP 2008004710 W EP2008004710 W EP 2008004710W WO 2009000425 A2 WO2009000425 A2 WO 2009000425A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- blister
- cover
- cover sheet
- cover film
- rfid
- Prior art date
Links
- 239000010408 film Substances 0.000 claims abstract description 27
- 239000003814 drug Substances 0.000 claims abstract description 26
- 239000013039 cover film Substances 0.000 claims abstract description 23
- 229940079593 drug Drugs 0.000 claims abstract description 21
- 239000004033 plastic Substances 0.000 claims description 9
- 229920003023 plastic Polymers 0.000 claims description 9
- 238000007789 sealing Methods 0.000 claims description 7
- 229910052751 metal Inorganic materials 0.000 claims description 6
- 239000002184 metal Substances 0.000 claims description 6
- 239000004020 conductor Substances 0.000 claims description 5
- 229920001577 copolymer Polymers 0.000 claims description 5
- 238000004891 communication Methods 0.000 claims description 4
- 238000005516 engineering process Methods 0.000 claims description 4
- 239000004922 lacquer Substances 0.000 claims description 4
- 229920004439 Aclar® Polymers 0.000 claims description 3
- 239000005023 polychlorotrifluoroethylene (PCTFE) polymer Substances 0.000 claims description 3
- 230000003213 activating effect Effects 0.000 claims description 2
- 239000003973 paint Substances 0.000 claims description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 229920001940 conductive polymer Polymers 0.000 claims 1
- 229910002804 graphite Inorganic materials 0.000 claims 1
- 239000010439 graphite Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 230000004913 activation Effects 0.000 abstract description 3
- 238000009434 installation Methods 0.000 abstract description 2
- 239000011888 foil Substances 0.000 description 15
- 239000010410 layer Substances 0.000 description 12
- -1 for example Polymers 0.000 description 9
- 239000000463 material Substances 0.000 description 9
- 229910052782 aluminium Inorganic materials 0.000 description 8
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical group [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 8
- 239000004698 Polyethylene Substances 0.000 description 6
- 239000000945 filler Substances 0.000 description 6
- 239000004800 polyvinyl chloride Substances 0.000 description 6
- 239000004743 Polypropylene Substances 0.000 description 5
- 229920000642 polymer Polymers 0.000 description 5
- 229920000573 polyethylene Polymers 0.000 description 4
- 229920000098 polyolefin Polymers 0.000 description 4
- 239000002131 composite material Substances 0.000 description 3
- 239000011159 matrix material Substances 0.000 description 3
- 229920000139 polyethylene terephthalate Polymers 0.000 description 3
- 239000005020 polyethylene terephthalate Substances 0.000 description 3
- 229910052623 talc Inorganic materials 0.000 description 3
- 235000012222 talc Nutrition 0.000 description 3
- 239000000454 talc Substances 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 239000004793 Polystyrene Substances 0.000 description 2
- 229920001328 Polyvinylidene chloride Polymers 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000005670 electromagnetic radiation Effects 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 239000002985 plastic film Substances 0.000 description 2
- 229920006255 plastic film Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 239000005033 polyvinylidene chloride Substances 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 239000005977 Ethylene Substances 0.000 description 1
- 239000013032 Hydrocarbon resin Substances 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 210000003811 finger Anatomy 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 239000004920 heat-sealing lacquer Substances 0.000 description 1
- 229920006270 hydrocarbon resin Polymers 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 238000012153 long-term therapy Methods 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 238000010295 mobile communication Methods 0.000 description 1
- 230000008450 motivation Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 229920002493 poly(chlorotrifluoroethylene) Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229920001897 terpolymer Polymers 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 230000002024 thermoprotective effect Effects 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 210000003813 thumb Anatomy 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
- 229910000859 α-Fe Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
- A61J1/035—Blister-type containers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/32—Layered products comprising a layer of synthetic resin comprising polyolefins
- B32B27/325—Layered products comprising a layer of synthetic resin comprising polyolefins comprising polycycloolefins
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/36—Layered products comprising a layer of synthetic resin comprising polyesters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B3/00—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form
- B32B3/02—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form characterised by features of form at particular places, e.g. in edge regions
- B32B3/08—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form characterised by features of form at particular places, e.g. in edge regions characterised by added members at particular parts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
- B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
- B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
- B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
- B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J2205/00—General identification or selection means
- A61J2205/60—General identification or selection means using magnetic or electronic identifications, e.g. chips, RFID, electronic tags
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/30—Properties of the layers or laminate having particular thermal properties
- B32B2307/31—Heat sealable
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2439/00—Containers; Receptacles
- B32B2439/80—Medical packaging
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2203/00—Decoration means, markings, information elements, contents indicators
- B65D2203/10—Transponders
Definitions
- the invention relates to a system for identifying and verifying the authenticity of a blister pack and for installing or activating software to assist a patient in controlling drug intake.
- Known push-through or blister packs consist of a blister base part and a cover foil which is sealed against the blister bottom part and closes the pack.
- a blister pack known for metered packaging of pharmaceutical products, such as tablets usually has a multiplicity of individual small containers in the form of cup-shaped depressions formed in the bottom blister in the blister bottom part for receiving the tablets. To remove a single tablet from a blister pack, the corresponding recess is pressed in the bottom part and in this case the tablet pushed through the lid material.
- the cover sheet is an aluminum foil or a composite foil of an aluminum foil with further layers of plastic or paper.
- the aluminum foil is a preferred lidding material for blister packs, since at the selected thicknesses of the lid materials relatively low breaking forces are necessary, the required piercing energy is thus low and the aluminum has a low elongation.
- the bottom part of the blister pack consists of plastic, such as, for example, PVC, polyamide, polyolefin, polyethylene terephthalate and composite films constructed of at least one of these materials and optionally also containing an aluminum foil.
- plastic pervious films In the context of the development of unmixed blister packs, plastic pervious films have already been proposed, whereby the puncture property of the plastic film is achieved by embedding fillers in the matrix.
- the fillers are considered in terms of their composition and their
- BESTATIGUNGSKOPIE partly chosen so that a weakening of the surrounding plastic matrix occurs, whereby the puncture resistance of the film is lowered so that the packaged goods can push through tearing or breaking the film through them. Due to the requirement that the selection of the fillers and in particular their proportions in the plastic matrix, the puncture property of the film should be ensured, resulting always opaque press-through films.
- EP-A-0 613 832 discloses a metal foil-free cover sheet comprising at least one polyolefin or polyester-based thermoplastic film having a filler content of 5 to 50% by weight.
- Preferred plastic is polyethylene
- fillers are, for example, chalk and talc.
- a transparent push-through foil with a polyolefin-containing polymer phase is known.
- the polymer phase contains a hydrocarbon resin component in dissolved form with pendant cyclic groups on the polymer chain.
- Preferred polyolefins are polyethylene, polypropylene or a co- or terpolymer of ethylene and / or propylene.
- filler such as chalk or talc, may be embedded in the polymer composition.
- a control, memory and motivation of the patient can be the success of one Significantly increase therapy and thus lead to a reduction in costs.
- All previous systems available on the market detect an opening of the packaging, which is also considered as taking the medication. If then the drug is really taken, can not be determined with most conventional systems. As a rule, however, a patient only bothers to open a package if he really wants to take the medication.
- Some packages help the patient to take the medications by visibly displaying the times of taking (for example, days of the week) on the package from the outside.
- Printed conductors arranged directly on the blister pack are disclosed, for example, in US Pat. No. 4,616,316, US Pat. No. 4,617,557, EP 0 972 507 A1, EP 0 129 785 A1 and US2007 / 0084746 A1.
- the blister pack with the tracks are connected to dataloggers, which record every change of the contacts and record the time of the change. The data is usually read out at the end, thus controlling the time of taking it. Even systems without data output are known; they will issue warnings and instructions when not taking proper medication via a display.
- the invention has for its object to provide a system which in a simple and reliable way, an identification and verification of the authenticity of a blister pack and at the same time installation or activation of software to support the control of a drug taking by a patient allows and no electronic components and Batteries on the blister pack required.
- a system which comprises:
- a push-through pack with a blister base part with at least one container formed out of a bottom foil, containing a tablet or similar medicament portion, and a push-through cover foil sealed against the blister bottom part,
- the RFID reader is part of a mobile phone, in particular a mobile phone with NFC (Near Field Communication) technology.
- NFC Near Field Communication
- LF low frequency, 125kHz
- HF 13.56 MHz
- UHF very small dipoles and also very well suited.
- the removal of medicines from the blister package usually already causes the destruction of a very small part of the RFID antenna, which drastically alters its resonance frequency.
- RFID tags are usually passive systems, ie they are only active if there is sufficient electromagnetic radiation above the RFID antenna in order to build up a sufficiently large operating voltage. Passive RFID tags therefore do not require a battery and are available on demand. Upon activation, the RFID tags return information in the form of a number as an individual identification identifier to the RFID reader. This number is unique, ie there is only one chip worldwide with this number. The numbers are usually 96 bit and allow about 8 x 10 28 different numbers. Furthermore, there are RFID chips that contain additional variable information, but these are relatively expensive.
- the RFID antennas can not be directly applied to a metal surface as this would attenuate the electromagnetic radiation too much.
- conventional aluminum foil as a cover film spacers would have to be provided, which, however, would significantly limit the compactness and function of the entire system.
- a metal foil-free cover film as is known for example from DE 196 13 960 A1
- the problem can be solved.
- the known metal foil-free cover films have the disadvantage that they contain additives, such as e.g. Talcum, exhibit. Without these additives, however, the brittleness of these films is too low for use as printable cover films.
- the invention is therefore based on the further object of providing a metal foil-free cover film which is suitable for sealing against all common base materials, which is transparent and at the same time has a brittleness that is compatible with a conventional push-through film containing an aluminum foil has comparable puncture properties.
- the cover film contains at least one layer of cycloolefin copolymer (COC).
- Cycloolefin copolymer is a highly transparent material with excellent barrier to water vapor transmission, can be coextruded with other materials such as polyethylene or polypropylene, and is also very brittle. These properties provide ideal conditions for the use of cycloolefin copolymer (COC) for the production of push-through films. It is possible with this material für diruden achieve with für diurformen similar to the fürdschreibfolien produced in large quantities mainly from aluminum foil of a thickness of 20 microns.
- the cover film is preferably provided in layers on the side facing against the blister side with a hot-sealing lacquer layer or a coextruded heat seal, the seal to blister base made of PVC, ACLAR ®, PP, PE, PS, Formpack ® or PA.
- the cover sheet with a thermally stable at sealing temperature paint layer or with a coextruded, at sealing temperature thermally stable plastic layer preferably from COC, PP, PA or PET, be provided.
- the cover film has a preferred thickness of 5 to 60 .mu.m, in particular 10 to 30 .mu.m.
- the blister bottom part consists of a material whose chemical structure is compatible with that of the plastic film sealed against the blister bottom part.
- materials used to make blister sheet parts are films of PVC, PVDC, PP, PET, PE, PS; PA and composite films such as PVC / ACLAR® (PCTFE) 1 PVC / PVDC and COC or FORMPACK® (AI-AI BIister).
- both the cover foil and the bottom foil can be printed.
- a mobile telephone equipped with NFC reads the individual identification code stored in the RFID chip when approaching the blister pack.
- This unambiguous ID number is automatically matched by the mobile phone with NFC technology to a central database and thus leads to feedback from the pharmaceutical manufacturer to the mobile phone.
- the authenticity of the blister pack can be reconfirmed by the manufacturer.
- corresponding programs or program modules can be loaded on the mobile phone.
- the software may include enhanced functionality by detecting additional blister packs with RFID tags that are specifically tailored to the combination of drugs for a patient.
- Other features include including data collected by other devices and transmitted via NFC or Bluetooth, such as blood pressure, heart rate, temperature and more. to be triggered.
- FIG. 1 is a plan view of the Blisterteilteil a blister pack.
- FIG. 2 shows a cross section through the blister pack of FIG. 1 along the line I-I;
- - Fig. 3 is a plan view of the cover sheet of the blister pack of
- FIG. 4 shows a cross section through a first cover sheet
- FIG. 5 shows a cross section through a second cover film
- FIG. 6 shows a system for controlling a medication intake.
- a blister pack 10 shown in Figs. 1 to 3 consists of a Blisterteil 12 formed out of a bottom foil, cup-shaped containers 14.
- the containers 14 are tablets 16.
- As a closure for the containers 14 is a the openings of the containers 14 spanning cover sheet 18 sealed against the blister base 12.
- the cover sheet 18 is printed with a pattern (FIG. 3).
- one of the tablets 16 has already been ejected from its container 14 through the cover film 18.
- the contrast difference between the open container with the cover sheet removed and the cover sheet 18 printed with a pattern is clearly recognizable for image evaluation.
- an RFID tag 70 a with an RFID chip 72 a and an RFID antenna 74 a is arranged in a non-destructible area on the cover sheet 18.
- the RFID antenna 74 a may also be arranged peripherally on the edge of the cover sheet 18.
- a first cover film 18 shown by way of example in FIG. 4 consists of a core film 20 made of mLLDPE (metallocene-based linear polyethylene lower Density) of a thickness of 10 .mu.m with COC films 22, 24 coextruded on both sides, each having a thickness of 5 .mu.m.
- the later to be sealed against a Blister foundedteil 12 side of the cover sheet 18 is coated with a Heissgueellacktik 26 has a thickness of 2 microns, optionally provided with a printed outside with a transparent protective lacquer layer 28 of a thickness of 2 microns.
- a second embodiment of a cover film 18, shown by way of example in FIG. 5, consists of a core film 30 made of COC with a thickness of 10 .mu.m and films of 5 .mu.m thickness coextruded on both sides.
- the film of cover sheet 18, which is later to be sealed against a blister sheet part 12 made of PVC, is a heat-sealable layer 32; the film on the outside of the other cover sheet 18 is a thermo-protective layer 34.
- a system shown in FIG. 6 by way of example for controlling a medicament intake or a removal of a tablet 16 from a blister pack 10 comprises a mobile telephone 42 for receiving and transmitting information, eg in the form of SMS (Short Message Service) short message.
- a mobile radio network 44 for example a GSM (Global System for Mobile Communications) or a UMTS (Universal Mobile Telecommunications System) mobile radio network or another mobile radio network, for example a satellite-based mobile radio network or a WLAN (Wireless Local Area Network).
- GSM Global System for Mobile Communications
- UMTS Universal Mobile Telecommunications System
- WLAN Wireless Local Area Network
- the system further comprises a computer system 46 having a transceiver unit 48 for transmitting and receiving information over the cellular network 44, a computer unit 50, and a database 52 associated with the computer unit 50 with the stored data including instructions for a patient to take the medication Identification 40 of the blister packs 10th LIST OF REFERENCE NUMERALS
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Primary Health Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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Abstract
La présente invention concerne un système d'identification et de vérification de l'intégrité d'un emballage sous blister (10) et d'installation ou d'activation d'un logiciel d'assistance au contrôle de la prise de médicaments par un patient. Le système comprend : un emballage sous blister (10) présentant une partie fond de blister (12), au moins un contenant (14) formé à partir d'un film de fond et dans lequel se trouve un comprimé (16) ou une dose médicamenteuse analogue, et un film de recouvrement (18) extrudable scellé contre la partie fond de blister (12); une étiquette RFID (70a) disposée sur l'emballage sous blister (10) et comprenant une puce RFID (72a) et une antenne RFID (74a); et un lecteur RFID associé au patient.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08773397A EP2160171A2 (fr) | 2007-06-22 | 2008-06-12 | Système de vérification de l'intégrité d'un emballage sous blister |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH10062007 | 2007-06-22 | ||
CH01006/07 | 2007-06-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009000425A2 true WO2009000425A2 (fr) | 2008-12-31 |
WO2009000425A3 WO2009000425A3 (fr) | 2009-03-12 |
Family
ID=39059612
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2008/004710 WO2009000425A2 (fr) | 2007-06-22 | 2008-06-12 | Système de vérification de l'intégrité d'un emballage sous blister |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP2160171A2 (fr) |
WO (1) | WO2009000425A2 (fr) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110037485A1 (en) * | 2008-04-28 | 2011-02-17 | Amcor Flexibles Kreuzlingen Ltd. | Covering and sealing film for a pack and a method for determining the opening state of a pack |
WO2012103564A1 (fr) * | 2011-01-31 | 2012-08-09 | Seibersdorf Labor Gmbh | Contenant et emballage unitaire |
WO2014075119A3 (fr) * | 2012-11-15 | 2014-08-14 | Ait Austrian Institute Of Technology Gmbh | Dispositif et procédé de production, de dosage et d'emballage de médicaments |
EP2577573B1 (fr) * | 2010-06-07 | 2016-02-10 | Boehringer Ingelheim International GmbH | Système de sécurité doté d'un transpondeur et d'un appareil de lecture d'un système rfid |
WO2016070272A1 (fr) * | 2014-11-04 | 2016-05-12 | Intelligent Devices Sezc Inc. | Moyens pour contrôler la compliance, faciliter la distribution automatique et protéger les enfants de médicaments conditionnés en bande |
US12020099B2 (en) | 2021-09-07 | 2024-06-25 | Schreiner Group Gmbh & Co. Kg | Label with RFID function |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
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WO1997014157A1 (fr) * | 1995-10-07 | 1997-04-17 | Img Group Limited | Composant de circuit electrique forme par impression directe d'un liquide conducteur sur un substrat |
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WO2005011564A1 (fr) * | 2003-07-28 | 2005-02-10 | Hueck Folien Gmbh & Co. Kg | Dispositif pour conserver des articles solides et/ou liquides et/ou gazeux |
WO2006007867A1 (fr) * | 2004-07-20 | 2006-01-26 | Schreiner Group Gmbh & Co. Kg | Plaquette de support de produits |
DE202005017891U1 (de) * | 2005-10-12 | 2006-11-16 | Alcan Technology & Management Ag | Kaltverformbares Laminat für Bodenteile von Blisterverpackungen |
WO2007043858A2 (fr) * | 2005-09-02 | 2007-04-19 | Kort, Willem, Theo | Plaquette alveolaire dotee d'un systeme de surveillance de contenu (otcm) a composants electroniques polymeres imprimes |
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2008
- 2008-06-12 WO PCT/EP2008/004710 patent/WO2009000425A2/fr active Application Filing
- 2008-06-12 EP EP08773397A patent/EP2160171A2/fr not_active Withdrawn
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WO1997014157A1 (fr) * | 1995-10-07 | 1997-04-17 | Img Group Limited | Composant de circuit electrique forme par impression directe d'un liquide conducteur sur un substrat |
US20030063524A1 (en) * | 2000-07-07 | 2003-04-03 | Niemiec Mark A. | Drug delivery management system |
WO2005011564A1 (fr) * | 2003-07-28 | 2005-02-10 | Hueck Folien Gmbh & Co. Kg | Dispositif pour conserver des articles solides et/ou liquides et/ou gazeux |
WO2006007867A1 (fr) * | 2004-07-20 | 2006-01-26 | Schreiner Group Gmbh & Co. Kg | Plaquette de support de produits |
WO2007043858A2 (fr) * | 2005-09-02 | 2007-04-19 | Kort, Willem, Theo | Plaquette alveolaire dotee d'un systeme de surveillance de contenu (otcm) a composants electroniques polymeres imprimes |
DE202005017891U1 (de) * | 2005-10-12 | 2006-11-16 | Alcan Technology & Management Ag | Kaltverformbares Laminat für Bodenteile von Blisterverpackungen |
WO2007060588A1 (fr) * | 2005-11-23 | 2007-05-31 | Koninklijke Philips Electronics N.V. | Systeme de controle d’un distributeur de medicament |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110037485A1 (en) * | 2008-04-28 | 2011-02-17 | Amcor Flexibles Kreuzlingen Ltd. | Covering and sealing film for a pack and a method for determining the opening state of a pack |
EP2577573B1 (fr) * | 2010-06-07 | 2016-02-10 | Boehringer Ingelheim International GmbH | Système de sécurité doté d'un transpondeur et d'un appareil de lecture d'un système rfid |
WO2012103564A1 (fr) * | 2011-01-31 | 2012-08-09 | Seibersdorf Labor Gmbh | Contenant et emballage unitaire |
WO2014075119A3 (fr) * | 2012-11-15 | 2014-08-14 | Ait Austrian Institute Of Technology Gmbh | Dispositif et procédé de production, de dosage et d'emballage de médicaments |
AT513652A3 (de) * | 2012-11-15 | 2015-08-15 | Ait Austrian Inst Technology | Vorrichtung und Verfahren zur Herstellung, Dosierung und Verpackung von Arzneimitteln |
AT513652B1 (de) * | 2012-11-15 | 2015-10-15 | Ait Austrian Inst Technology | Vorrichtung und Verfahren zur Herstellung, Dosierung und Verpackung von Arzneimitteln |
US10342922B2 (en) | 2012-11-15 | 2019-07-09 | Ait Austrian Institute Of Technology Gmbh | Device and method for producing, dosing and packaging medicaments |
WO2016070272A1 (fr) * | 2014-11-04 | 2016-05-12 | Intelligent Devices Sezc Inc. | Moyens pour contrôler la compliance, faciliter la distribution automatique et protéger les enfants de médicaments conditionnés en bande |
US10588826B2 (en) | 2014-11-04 | 2020-03-17 | Intelligent Devices Sezc Inc. | Means for monitoring compliance, facilitating automatic dispensing and childproofing strip packaged medications |
US12020099B2 (en) | 2021-09-07 | 2024-06-25 | Schreiner Group Gmbh & Co. Kg | Label with RFID function |
Also Published As
Publication number | Publication date |
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EP2160171A2 (fr) | 2010-03-10 |
WO2009000425A3 (fr) | 2009-03-12 |
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