WO2008145177A1 - Module de vaporisateur pour anesthésie - Google Patents

Module de vaporisateur pour anesthésie Download PDF

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Publication number
WO2008145177A1
WO2008145177A1 PCT/EP2007/055152 EP2007055152W WO2008145177A1 WO 2008145177 A1 WO2008145177 A1 WO 2008145177A1 EP 2007055152 W EP2007055152 W EP 2007055152W WO 2008145177 A1 WO2008145177 A1 WO 2008145177A1
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WO
WIPO (PCT)
Prior art keywords
liquid
vaporization chamber
peltier element
vaporizer module
anaesthetic
Prior art date
Application number
PCT/EP2007/055152
Other languages
English (en)
Inventor
Kiomars Fathollahzadeh
Original Assignee
Maquet Critical Care Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maquet Critical Care Ab filed Critical Maquet Critical Care Ab
Priority to PCT/EP2007/055152 priority Critical patent/WO2008145177A1/fr
Publication of WO2008145177A1 publication Critical patent/WO2008145177A1/fr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/14Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • A61M16/18Vaporising devices for anaesthetic preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/14Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • A61M16/147Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase the respiratory gas not passing through the liquid container
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/36General characteristics of the apparatus related to heating or cooling
    • A61M2205/3673General characteristics of the apparatus related to heating or cooling thermo-electric, e.g. Peltier effect, thermocouples, semi-conductors

Definitions

  • the present invention relates to an anaesthetic vaporizer module according to the preamble of claim 1 , and an anaesthesia apparatus according to the preamble of claim 11.
  • a medical liquid in a container at a delivery pressure by means of pressurised gas.
  • the gas is inlet to the container from a pressurised gas source.
  • the gas exerts its pressure on the surface of the medical liquid and the pressurised liquid is delivered through a controllable outlet.
  • Such an apparatus is used for example in a vaporizer for liquid anaesthetic wherein a delivery apparatus delivers the liquid via an injector coupled to the outlet and into a flow of breathing gas.
  • a delivery apparatus delivers the liquid via an injector coupled to the outlet and into a flow of breathing gas.
  • the delivery apparatus is capable of delivering a certain volume of liquid with a high degree of repeatability.
  • the basic idea for an anaesthesia apparatus of this kind is that the delivered volume of liquid shall be dependent only on the differential pressure over the controllable outlet and on the time during which the outlet is open.
  • the temperature is an important parameter.
  • One of the challenges regarding the anaesthesia liquid container is to keep its temperature several degrees centigrade under the boiling point of the liquid in use.
  • the ambient temperature of the liquid container in an anaesthesia apparatus can be high due to the heat generated by electric components, heat elements, etc., and most anaesthesia liquids have low boiling points, especially Desflurane having a boiling temperature as low as 23 0 C at 1000 mbar absolute pressure, and approximately 4O 0 C at 2000 mbar absolute pressure, which may be a suitable working pressure for an anaesthesia vaporizer. This causes the anaesthetic liquid to be easily in equilibrium with gas, causing two main disadvantages:
  • boiling liquid causes bubbles in the medium which makes it difficult to deliver a correct and well controlled amount of the anaesthesia agent, especially in vaporizers with injecting mechanisms, since gas and liquid have different viscosities.
  • a pressure regulator arranged to regulate the supply of driving gas to the liquid container, ensures that the system does not suffer from under pressure.
  • the vaporization chamber in which the liquid anaesthetic is vaporized into the breathing gas of a patient needs adequate amount of heat energy to make sure that the liquid is vaporized even with high flow rates of the patients breathing gas, and to avoid condense of the vaporized anaesthetic after injection into the carrier gas flow. Otherwise, liquid drops may occur in the inhalation flow which makes it difficult to analyze the breathing gas composition before delivery to the patient.
  • the control of the vaporizer in an anaesthesia apparatus is, at least partially, based on the results of such an analysis and therefore, condensed anaesthetic in the inhalation flow may result in inaccurate anaesthetic dose delivery and hence jeopardize patient safety.
  • an electric heater is therefore used to heat the vaporization chamber to a desired temperature.
  • DE 102 32 605 discloses a dosing apparatus comprising a Peltier element arranged with its cold side against an outlet conduit leading the liquid anaesthetic from a liquid container to a vaporization chamber.
  • the warm side of the Peltier element is in turn connected to a heat exchanger via a metal shackle, which heat exchanger is disposed in the gas flow path to a patient and arranged to be struck by the liquid anaesthetic delivered by a delivery mechanism.
  • the liquid anaesthetic in the conduit between the liquid container and the vaporization chamber is being cooled while the liquid anaesthetic injected into the gas flow path to the patient is vaporized against a heat exchanger.
  • GB 2 254 005 discloses an anaesthetic evaporator comprising a Peltier element which abuts an evaporator container and which, by means of an appropriate control, is arranged to either cool or heat the evaporator container to obtain a temperature at which the vapour pressure of the anaesthetic assumes the desired pressure value.
  • WO 99/1 1312 discloses an anaesthetic vaporizer in which liquid anaesthetic enters a vaporization chamber through a fine needle which is in thermal contact with a heating/cooling surface to ensure complete vaporization of anaesthetic microdroplets on entry into the chamber.
  • the heating/cooling surface is thermally coupled with Peltier elements to adjust the temperature thereof by means of a microcontroller.
  • a vaporizer module comprising a liquid portion for holding anaesthetic liquid, a vaporization chamber arranged in fluid communication with the liquid portion for vaporizing said liquid into a carrier gas flow that is to be supplied to a subject, and at least one Peltier element connected to means for applying a DC current thereto, said at least one Peltier element being arranged in thermal contact with both the liquid portion and the vaporization chamber.
  • the present invention serves to simultaneously cool the anaesthetic liquid and heat the gas mixture into which the anaesthetic is vaporized.
  • the present invention thus simultaneously prevents formation of gas bubbles in the anaesthesia liquid and condensation of the vaporized anaesthetic.
  • the liquid portion of the vaporizer module may comprise a liquid container for holding the anaesthetic liquid and an outlet conduit for providing the liquid to the vaporization chamber.
  • the Peltier element(s) may be arranged between the liquid container and the vaporization chamber, and/or between the outlet conduit and the vaporization chamber.
  • the liquid portion comprises a wall portion substantially dividing the liquid portion into a "cooling basin” holding the liquid that is to be supplied to the vaporization chamber, and a reservoir in fluid communication with said cooling basin through an opening in the wall portion.
  • the wall portion is of a size and material reducing heat transfer between the liquid held in the cooling basin and the liquid held in the reservoir, and the Peltier element is arranged to butt against an outer surface of the cooling basin.
  • the liquid portion and/or the vaporization chamber is provided with a heat sink protruding into the anaesthetic liquid in the liquid portion and/or the breathing gas in the vaporization chamber to increase the rate of cooling and heating, respectively.
  • the vaporizer module comprises means for automatically controlling the DC current applied to the Peltier element(s) based on parameter values measured by temperature sensors within the liquid portion and the vaporization chamber of the vaporizer module. Automatic heat regulation of the vaporizer module eliminates the risk for human errors and frees resources for the medical professionals.
  • the vaporizer may comprise means for switching the polarity of the Peltier element, enabling transport of thermal energy in both directions.
  • Figure 1 schematically shows a first embodiment of the vaporizer module according to the present invention with a Peltier element disposed between the liquid container and the vaporization chamber.
  • Figure 2 shows another embodiment of the vaporizer module with a further Peltier element disposed between the outlet conduit of the liquid portion and the vaporization chamber.
  • Figure 3 schematically shows an embodiment of the vaporizer module with yet another alternative placement of a Peltier element.
  • Figure 4A and 4B schematically show embodiments of the vaporizer module according to the present invention comprising "cooling basins”.
  • Figure 5 schematically shows yet another embodiment of the vaporizer module according to the present invention comprising a heat sink.
  • Figure 6 schematically shows an embodiment of the vaporizer module according to the present invention arranged to allow automatic heat regulation of anaesthetic within the vaporizer module.
  • Figure 7 schematically shows an embodiment of the vaporizer module according to the present invention comprising an additional Peltier element for further optimizing the heat regulation of the anaesthetic in different parts of the vaporizer module.
  • Fig. 1 shows a vaporizer module 1 according to a first embodiment of the present invention.
  • the vaporizer module 1 comprises a liquid portion 2a, 2b comprising a liquid container 2a and an outlet conduit 2b, and a vaporization chamber 3.
  • a Peltier element 4 sometimes referred to as a thermo-electric cooler, connected to a power supply 5 for applying a DC current thereto, is arranged in thermal contact with the liquid portion 2a, 2b and the vaporization chamber 3.
  • the Peltier element 4 is arranged in thermal contact with the liquid container 2a and the vaporization chamber 3.
  • the liquid container 2a holds anaesthetic liquid 6 and a pressurized driving gas, illustrated by reference numeral 8.
  • the outlet conduit 2b delivers the liquid 6 through a controllable outlet 10 to the vaporization chamber 3 in which the liquid is vaporized into a gas mixture entering the vaporization chamber 3 via an inlet 14 and leaving the vaporization chamber via an outlet 16 connectable to the respiratory system of a patient via a breathing circuit (not shown).
  • the vaporization chamber 3 may solely comprise an outlet 16 to the breathing circuit/carrier gas and no inlet 14.
  • the vaporizer module 1 is hence arranged to be connectable to, or integrated in, an anaesthesia apparatus.
  • a pressure regulator 9 controls the delivery of driving gas to the liquid container 2a, supplied by a pressurized gas source through the conduit 12.
  • the pressure regulator 9 is normally automatically controlled by feedback regulation based on sensor measurements to maintain an even working pressure of the driving gas 8.
  • the amount of anaesthetic liquid delivered through the controllable outlet 10 can be controlled by altering the length and/or the number of injection pulses provided by the outlet 10.
  • an operator of the vaporizer module sets the desired concentration of anaesthetic in the breathing gases supplied to the patient via a user interface of the vaporizer module 1 or an anaesthesia apparatus to which the vaporizer module 1 is connected, whereupon the operation of the vaporizer module is automatically controlled by means of a sensor feedback system.
  • the Peltier element 4 is according to one embodiment of the invention arranged so that its cold side butt against the liquid container 2a and its warm side butt against the vaporization chamber 3, and hence serves to simultaneously cool the liquid container 2a while heating the vaporization chamber 3.
  • the DC current is automatically controlled by a control circuit further described below with reference made to Fig. 6.
  • a thermal interface material such as silicone -based greases, elastomeric pads, thermally conductive tapes, etc.
  • the thermal interface material also allows the Peltier element 4 to move slightly with temperature changes.
  • the thermal mass of the liquid container 2a and the vaporization chamber 3 should be as equal as possible in order to optimize the rate of heat transfer.
  • the volume of the vaporization chamber 3 is smaller than the volume of the liquid container 2a and, therefore, the thermal mass of the vaporization chamber 3 may be increased by an additional heat sink.
  • Such an additional heat sink may, for example, consist of a metal plate arranged between the Peltier element 4 and the vaporization chamber 3, or, if maximum cooling of the liquid container 2a and low to moderate heating of the vaporization chamber 3 is desired, of a metal plate arranged between two Peltier elements connected in series.
  • the liquid container 2a In order to obtain and maintain a low temperature of the liquid container 2a it is preferably thermally isolated from the ambient air and/or adjacent components. Thermal isolation of the liquid portion 2a, 2b in combination with the cooling achieved by means of the Peltier element 4 allow the vaporizer module 1 according to the present invention to be operated in high temperature environments and/or with decreased driving gas pressure. Preferably, the vaporization chamber 3 is also thermally isolated in order to avoid thermal radiation emitted there from to warm the liquid portion 2a, 2b.
  • the vaporizer module 1 may comprise one or several electric heaters 7 arranged in thermal contact with the vaporization chamber 3, making it possible to rise the temperature of the gas mixture in the vaporization chamber 3 without at the same time undesirably lower the temperature of the liquid anaesthetic 6 in the liquid portion 2a, 2b.
  • a Peltier element 4b is arranged between the outlet conduit 2b and the vaporization chamber 3.
  • This Peltier element may be used alone or in combination with the dashed Peltier element 4a arranged between the liquid container 2b and the vaporization chamber 3, as described above.
  • the outlet conduit 2b may be arranged to decline from the liquid container 2b to the controllable outlet 10, i.e.
  • a slanted outlet conduit 2b may, of course, be employed in all embodiments of the present invention disclosed herein.
  • Fig. 3 shows another embodiment of the vaporizer module 1, in which a Peltier element 4c is arranged to butt against substantially the whole bottom surface of the vaporization chamber 3 and substantially the whole top surface of the outlet conduit 2b.
  • the Peltier element 4c comprises a hole through which the outlet 10 penetrates.
  • a plurality of Peltier elements surrounding the outlet 10 can be used to achieve a similar effect.
  • the Peltier element 4c may be the only Peltier element arranged to transfer heat between the liquid portion 2a, 2b and the vaporization chamber 3 of the vaporizer module 1 , or it may be used in combination with a Peltier element 4a arranged between the liquid container 2a and the vaporization chamber 3, illustrated with dashed lines.
  • the outlet conduit 2b is preferably folded or arranged in a spiral to maximize the contact surface with the Peltier element 4c.
  • the bottom surface of the vaporization chamber 3 may be a circular disc and the outlet conduit 2b may be arranged to form a circular spiral whose outer winding substantially follows the circumference of the Peltier element 4c and which winds inwardly to end in the outlet 10, protruding from the centre of the spiral into the vaporization chamber 3 through the Peltier element 4c, as indicated by the dashed lines in Fig. 3.
  • Peltier elements 4a, 4b, 4c are used in the vaporizer module 1 , they are preferably operated with separately adjustable DC currents. As in the case with a single Peltier element, the separately adjustable DC currents are preferably automatically controlled by a control circuit on the basis of parameter values relating to, e.g., temperature and/or pressure measured by sensors disposed at strategic places in the liquid portion 2a, 2b and the vaporization chamber 3, as further described below with reference made to Fig. 6.
  • Fig. 4A shows another embodiment of the present invention, in which the liquid container is divided into a "cooling basin" 18a and a reservoir 19b by a wall portion 20a.
  • the wall portion 20a substantially separates the cooling basin 18a from the reservoir 19a but comprises a small opening 22a through which the anaesthetic liquid 6 can flow between the substantially separated portions of the liquid container 2a.
  • the wall portion 20a is made out of a material with low thermal conductibility to thermally isolate the liquid held in the cooling basin 18a from the liquid held in the reservoir 19a.
  • the Peltier element 4 is arranged to butt against an outer surface of the cooling basin 18a to convey heat energy there from to the vaporization chamber 3. Since the heat transfer between the liquid held in the cooling basin 18a and the liquid held in the reservoir 19a is reduced by the thermally isolating wall portion 20a, the liquid contained in the cooling basin 18a will be held at a lower temperature than the liquid 6 contained in the reservoir 19a. However, the cooling effect from the Peltier element 4 will, of course, also lower the temperature of the liquid contained outside the cooling basin 18a due to thermal conduction in the outer walls of the liquid container 2a, fluid conduction/convection through the opening 22a of the wall portion 20a, and some inevitable heat conduction through the wall portion 20a.
  • Fig. 4B shows another embodiment of the present invention in which the Peltier element 4c described above with reference made to Fig. 3 is used, and in which a wall portion 20b substantially separates the outlet conduit 2b from the liquid container 2a to form a cooling basin 18b and a reservoir 19b in a way similar to the one described above with reference made to Fig. 4A.
  • the wall portion 20b comprises a small opening 22b through which the anaesthetic liquid 6 can flow from the reservoir 19b to the cooling basin 18a.
  • the Peltier element 4c butts against substantially the whole bottom surface of the vaporizer chamber 3 and substantially the whole top surface of the cooling basin 18b to maximize heat transfer there between.
  • Fig. 5 shows another embodiment of the vaporizer module 1 according to the present invention, wherein the liquid container 2a and the vaporization chamber 3 comprises a heat sink 24.
  • the heat sink 24 comprises cooling fins extending into the anaesthetic liquid 6 in the liquid container 2a and into the gas mixture comprising the vaporized anaesthetic in the vaporization chamber 3.
  • the heat sink 24 serves to increase the contact area between the anaesthetic liquid 6 and the liquid container 6, and the contact area between the gas mixture passing the vaporization chamber 3 and the vaporization chamber 3, thus accelerating the cooling of the anaesthetic liquid 6 and the heating of the gas mixture, respectively.
  • the heat sink 24 protrudes from the part of the liquid container surface 2a and/or the vaporization chamber surface 3 that is adjacent to the Peltier element 4, as illustrated in the figure.
  • a heat sink may, of course, be used in any of the embodiments of the present invention described herein.
  • the top surface of the outlet conduit 2b and the bottom surface of the vaporization chamber 3, shown in Fig. 4B, may be provided with a heat sink extending into the cooling basin 18b and into the gas mixture inside the vaporization chamber 3, respectively.
  • the vaporizer module 1 comprises a first temperature sensor Tl arranged to measure the temperature of the liquid 6 in the liquid container 2a, and a second temperature sensor T2 arranged to measure the temperature of the gas mixture passing through the vaporization chamber 3.
  • the temperature sensors Tl, T2 are connected to a control unit 18 arranged to receive the measured temperature values.
  • the control unit 18 is in turn connected to the power supply 5 and comprises means for regulating the DC current applied to the Peltier element 4 by the power supply 5 based on the temperature values received from the temperature sensors T land T2.
  • the control unit 18 comprises means for comparing the measured temperature values with predetermined threshold values and adjust the current applied to the Peltier element 4 based on the result of the comparison.
  • the threshold values are chosen depending on the particular anaesthetic in use.
  • a certain type of vaporizer module is used for a certain type of anaesthetic agent, and each vaporizer module type comprises standardized identification means in order for an anaesthesia apparatus to which the vaporizer module is connected to automatically identify the vaporizer module type, and hence the type of anaesthetic agent.
  • the vaporizer module 1 comprises such identification means.
  • the central control unit 18 of an anaesthesia apparatus to which the vaporizer module 1 is connected can automatically choose suitable threshold values for the measured temperatures in dependence of the particular anaesthetic agent in use.
  • the vaporizer module 1 or the anaesthesia apparatus to which it is connected may comprise analyzing means known in the art for automatic identification of the anaesthetic agent.
  • the power supply 5 is also connected to the electric heaters 7, in which case the control unit 18 may be further arranged to control the amount of heat supplied to the vaporization chamber 3 by the electric heaters 7 based on the measured temperature values received from the temperature sensors Tl and T2.
  • the DC current applied to the Peltier element 4 and hence the heat regulation of the vaporizer module 1 is controlled by a control circuit comprising the control unit 18 and the power supply 5.
  • These components may be included in the vaporizer module 1 or they may be, or form a part of, a central control unit in an anaesthesia apparatus to which the vaporizer module 1 is detachably connected.
  • the vaporizer module 1 may, for example, be connected to the anaesthesia apparatus via a data bus through which signals indicative of the temperature values measured by the temperature sensors Tl and T2 are provided to the central control unit of the anaesthesia apparatus.
  • the anaesthesia apparatus preferably comprises means for electronically identifying what type of vaporizer module 1 that is connected to the apparatus, and hence what type of anaesthetic agent that is to be used.
  • the central control unit can automatically chose suitable threshold values for the temperature of the anaesthetic liquid 6 and the gas mixture inside the vaporization chamber 3 and control the heat regulation of the vaporizer module 1 accordingly.
  • the anaesthesia apparatus may comprise analyzing means known in the art for automatically determining which anaesthetic agent is used.
  • the vaporizer module 1 further comprises a pressure sensor disposed to measure the pressure of the driving gas 8 in the liquid container 2a.
  • the vaporizer module 1 is arranged to provide the measured pressure values to the central control unit of the anaesthesia apparatus in order for the central control unit to control the pressure regulator 9 based on measured driving gas pressure.
  • the temperature sensors Tl and T2 may, of course, be disposed elsewhere than shown in Fig. 6.
  • the temperature sensor Tl may, for example, be disposed in the outlet conduit 2b. More than one temperature sensor within the liquid portion 2a, 2b and/or more than one temperature sensor within the vaporization chamber 3 may also be employed to further optimize the temperature regulation of the anaesthetic within the vaporizer module 1.
  • the vaporizer module 1 may further comprise an alarm indicator which sets of an alarm if the temperature values measured by the temperature sensors Tl and T2 exceed a critical value.
  • the vaporizer module 1, or the anaesthesia apparatus to which it can be connected may also comprise means for manually overriding the automatic heat regulation system of the vaporizer module 1 in case of system malfunction or other unforeseen events that may jeopardize patient safety.
  • Fig. 7 shows how temperature differences between the anaesthetic liquid 6 in different parts of the liquid portion 2a, 2b can be minimized by means of an additional Peltier element 4d.
  • an additional Peltier element 4d is arranged in thermal contact with the liquid portion 2a and the outlet conduit 2b in order to transfer heat energy from the outlet conduit 2b to the liquid container 2b.
  • the Peltier element 4a in turn conveys the heat on from the liquid portion 2a to the vaporization chamber 3.
  • the use of the additional Peltier element 4d is particularly suitable when the ambient temperature is low, and especially when using anaesthetic agents with high boiling points, such as Isoflurane. In such circumstances a temperature sensor for measuring the temperature of the anaesthetic liquid within the outlet conduit 2b is required for automatic heat regulation.
  • the main purpose of the present invention is to use at least one Peltier element to simultaneously cool the liquid anaesthetic in the liquid portion of a vaporizer module while heating the carrier gas flow into which the anaesthetic liquid is vaporized in a vaporization chamber, it may sometimes be desirable to reverse the direction of heat transfer. Therefore, the vaporizer module 1 of the present invention preferably comprises means for changing the polarity of the DC current applied to the Peltier element 4, 4a-c to cause the Peltier element 4, 4a-c to convey heat from the vaporization chamber 3 to the liquid portion 2a, 2b.
  • the polarity may be automatically changed by the control unit as response to temperature values measured by temperature sensors disposed inside the liquid portion 2a, 2b and the vaporization chamber 3.
  • Fig. 1-7 illustrate a vaporizer module 1 in which the liquid portion comprises a liquid container 2a and an outlet conduit 2b
  • the liquid portion of the vaporizer module 1 does not have to include a separate outlet conduit 2b.
  • the controllable outlet 10 may be arranged directly in an opening in the liquid container 2a.
  • the term "liquid portion" should therefore be interpreted as the part of the vaporizer module 1 in which the anaesthetic is liquid.
  • an embodiment according to the present invention may comprise a heat sink with cooling fins protruding into a cooling basin in a liquid container being cooled by a Peltier element whose driving DC current is automatically controlled by a control unit in dependence of parameter values received from a temperature sensor disposed in said cooling basin.

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  • Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)

Abstract

La présente invention concerne un module de vaporisateur (1) comprenant une partie liquide (2a, 2b) pour contenir un liquide anesthésique (6), une chambre de vaporisation (3) disposée en communication fluidique avec la partie liquide (2a, 2b) pour vaporiser ledit liquide en un écoulement de gaz porteur qui doit être transmis à un sujet, et au moins un élément à effet Peltier (4 ; 4a ; 4b ; 4c) raccordé à des moyens (5) pour appliquer un courant continu à celui-ci, ledit ou lesdits éléments à effet Peltier (4; 4a ; 4b ; 4c) étant agencés en contact thermique à la fois avec la partie liquide (2a, 2b) et la chambre de vaporisation (3). Par l'agencement d'un élément à effet Peltier (4 ; 4a ; 4b ; 4c) en contact thermique à la fois avec la partie liquide (2a, 2b) et la chambre de vaporisation (3), la présente invention sert simultanément à refroidir le liquide anesthésique (6) et à chauffer le mélange gazeux dans lequel l'anesthésique est vaporisé.
PCT/EP2007/055152 2007-05-29 2007-05-29 Module de vaporisateur pour anesthésie WO2008145177A1 (fr)

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PCT/EP2007/055152 WO2008145177A1 (fr) 2007-05-29 2007-05-29 Module de vaporisateur pour anesthésie

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012084042A1 (fr) * 2010-12-22 2012-06-28 Maquet Critical Care Ab Vaporisateur anesthésique perfectionné pour un appareil respiratoire et procédé de vaporisation d'un agent anesthésique liquide dans un tel vaporisateur anesthésique
US8752544B2 (en) 2011-03-21 2014-06-17 General Electric Company Medical vaporizer and method of monitoring of a medical vaporizer
WO2015017342A1 (fr) * 2013-07-29 2015-02-05 Oregon Health & Science University Vaporisateur d'anesthésique
CN104623773A (zh) * 2015-01-29 2015-05-20 钱莹 一种麻醉蒸发器
US10610659B2 (en) 2017-03-23 2020-04-07 General Electric Company Gas mixer incorporating sensors for measuring flow and concentration
US10946160B2 (en) 2017-03-23 2021-03-16 General Electric Company Medical vaporizer with carrier gas characterization, measurement, and/or compensation

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992004930A1 (fr) * 1990-09-25 1992-04-02 The Boc Group Plc Cuvette pour un vaporisateur d'agent anesthesique
GB2254005A (en) * 1991-03-28 1992-09-30 Draegerwerk Ag Anaesthetic evaporator for dosing different anaesthetics
GB2254383A (en) * 1991-03-28 1992-10-07 Draegerwerk Ag Pumping arrangement for the dosed conveyance of liquids
DE4111138A1 (de) * 1991-04-06 1992-10-08 Draegerwerk Ag Beatmungsvorrichtung mit anwaermung des atemgases
WO1999011312A1 (fr) * 1997-08-30 1999-03-11 Medical Industrial Equipment Limited Vaporisateur d'anesthesie
DE10232605C1 (de) * 2002-07-18 2003-11-20 Draeger Medical Ag Vorrichtung und Verfahren zur Narkosemitteldosierung

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992004930A1 (fr) * 1990-09-25 1992-04-02 The Boc Group Plc Cuvette pour un vaporisateur d'agent anesthesique
GB2254005A (en) * 1991-03-28 1992-09-30 Draegerwerk Ag Anaesthetic evaporator for dosing different anaesthetics
GB2254383A (en) * 1991-03-28 1992-10-07 Draegerwerk Ag Pumping arrangement for the dosed conveyance of liquids
DE4111138A1 (de) * 1991-04-06 1992-10-08 Draegerwerk Ag Beatmungsvorrichtung mit anwaermung des atemgases
WO1999011312A1 (fr) * 1997-08-30 1999-03-11 Medical Industrial Equipment Limited Vaporisateur d'anesthesie
DE10232605C1 (de) * 2002-07-18 2003-11-20 Draeger Medical Ag Vorrichtung und Verfahren zur Narkosemitteldosierung

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012084042A1 (fr) * 2010-12-22 2012-06-28 Maquet Critical Care Ab Vaporisateur anesthésique perfectionné pour un appareil respiratoire et procédé de vaporisation d'un agent anesthésique liquide dans un tel vaporisateur anesthésique
US9370636B2 (en) 2010-12-22 2016-06-21 Maquet Critical Care Ab Anesthetic vaporizer for a breathing apparatus and method for operation thereof to vaporize a liquid anesthetic agent
US8752544B2 (en) 2011-03-21 2014-06-17 General Electric Company Medical vaporizer and method of monitoring of a medical vaporizer
US9586020B2 (en) 2011-03-21 2017-03-07 General Electric Company Medical vaporizer and method of monitoring of a medical vaporizer
WO2015017342A1 (fr) * 2013-07-29 2015-02-05 Oregon Health & Science University Vaporisateur d'anesthésique
CN104623773A (zh) * 2015-01-29 2015-05-20 钱莹 一种麻醉蒸发器
US10610659B2 (en) 2017-03-23 2020-04-07 General Electric Company Gas mixer incorporating sensors for measuring flow and concentration
US10946160B2 (en) 2017-03-23 2021-03-16 General Electric Company Medical vaporizer with carrier gas characterization, measurement, and/or compensation

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