WO2008136465A1 - 電気泳動チップ、電気泳動装置およびキャピラリー電気泳動法による試料の分析方法 - Google Patents

電気泳動チップ、電気泳動装置およびキャピラリー電気泳動法による試料の分析方法 Download PDF

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Publication number
WO2008136465A1
WO2008136465A1 PCT/JP2008/058206 JP2008058206W WO2008136465A1 WO 2008136465 A1 WO2008136465 A1 WO 2008136465A1 JP 2008058206 W JP2008058206 W JP 2008058206W WO 2008136465 A1 WO2008136465 A1 WO 2008136465A1
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WO
WIPO (PCT)
Prior art keywords
sample
electrophoresis
bath
introduction
sample analyzing
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PCT/JP2008/058206
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English (en)
French (fr)
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WO2008136465A8 (ja
Inventor
Yoshihide Tanaka
Yusuke Nakayama
Satoshi Yonehara
Original Assignee
National Institute Of Advanced Industrial Science And Technology
Arkray, Inc.
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Publication date
Application filed by National Institute Of Advanced Industrial Science And Technology, Arkray, Inc. filed Critical National Institute Of Advanced Industrial Science And Technology
Priority to EP14173977.1A priority Critical patent/EP2803992B1/en
Priority to JP2008542547A priority patent/JP5559967B2/ja
Priority to EP08752216A priority patent/EP2148193A4/en
Priority to CN2008800012675A priority patent/CN101568830B/zh
Priority to US12/515,994 priority patent/US9494553B2/en
Publication of WO2008136465A1 publication Critical patent/WO2008136465A1/ja
Publication of WO2008136465A8 publication Critical patent/WO2008136465A8/ja

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44743—Introducing samples

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

　チップの小型化および簡略化が可能で、且つ、試料を高精度に分析可能な電気泳動チップを提供する。 　上基板４と、下基板１と、導入槽２ａと、回収槽２ｂと、試料分析用のキャピラリー流路３ｘとを含み、前記下基板１上に、前記導入槽２ａと前記回収槽２ｂとが形成され、前記導入槽２ａと前記回収槽２ｂとが、前記試料分析用のキャピラリー流路３ｘで連通され、前記導入槽２ａに測定対象となる試料が導入され、前記導入槽２ａと前記回収槽２ｂとの間に電位差を生じさせることで、電気泳動により、前記試料分析用のキャピラリー流路３ｘに前記試料が直接導入され、前記試料分析用のキャピラリー流路３ｘにおいて、前記試料の分離中も前記試料が連続的に供給されている状態で前記試料の分析が行われる。
PCT/JP2008/058206 2007-04-27 2008-04-28 電気泳動チップ、電気泳動装置およびキャピラリー電気泳動法による試料の分析方法 WO2008136465A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP14173977.1A EP2803992B1 (en) 2007-04-27 2008-04-28 Sample analyzing method by capillary electrophoresis method
JP2008542547A JP5559967B2 (ja) 2007-04-27 2008-04-28 電気泳動チップ、電気泳動装置およびキャピラリー電気泳動法による試料の分析方法
EP08752216A EP2148193A4 (en) 2007-04-27 2008-04-28 ELECTROPHORESIS CHIP, ELECTROPHORESIS DEVICE AND SAMPLE ANALYSIS METHOD BY CAPILLARY ELECTROPHORESIS METHOD
CN2008800012675A CN101568830B (zh) 2007-04-27 2008-04-28 电泳芯片、电泳装置以及利用毛细电泳法的试样分析方法
US12/515,994 US9494553B2 (en) 2007-04-27 2008-04-28 Electrophoresis chip, electrophoresis apparatus, and method for analyzing sample by capillary electrophoresis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007119262 2007-04-27
JP2007-119262 2007-04-27

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WO2008136465A1 true WO2008136465A1 (ja) 2008-11-13
WO2008136465A8 WO2008136465A8 (ja) 2009-03-12

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Country Status (5)

Country Link
US (1) US9494553B2 (ja)
EP (2) EP2148193A4 (ja)
JP (3) JP5559967B2 (ja)
CN (1) CN101568830B (ja)
WO (1) WO2008136465A1 (ja)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2352020A2 (en) 2010-01-19 2011-08-03 Arkray, Inc. Method for analyzing sample by electrophoresis and use of the same
WO2012017515A1 (ja) * 2010-08-03 2012-02-09 ミライアル株式会社 マイクロ流路デバイス
EP2420844A1 (en) 2010-08-16 2012-02-22 Arkray, Inc. Analytical method of hemoglobin
JP2012515927A (ja) * 2009-01-23 2012-07-12 ドレクセル・ユニバーシティー 炎症を検出するための量子ドットを用いた装置および方法
JP2013117522A (ja) * 2011-10-31 2013-06-13 Arkray Inc 基材の修飾方法
EP2993467A1 (en) 2014-09-04 2016-03-09 ARKRAY, Inc. Analysis method and analysis system
EP2998732A1 (en) 2014-09-11 2016-03-23 ARKRAY, Inc. Analysis method, analysis chip, and analysis system
EP3179243A1 (en) 2015-12-09 2017-06-14 ARKRAY, Inc. Analytical tool for capillary electrophoresis with pressure fluctuation reducer
JP2017106904A (ja) * 2015-12-09 2017-06-15 アークレイ株式会社 分析用具および分析システム
EP3438654A2 (en) 2017-08-03 2019-02-06 ARKRAY, Inc. Analysis chip
EP3608663A1 (en) 2018-08-08 2020-02-12 ARKRAY, Inc. Analysis chip device

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EP2623975B1 (en) * 2006-12-26 2016-02-03 Sekisui Chemical Co., Ltd. Stable hemoglobin A1c and glucose measurement method
EP2400034B1 (en) * 2010-06-23 2016-08-24 ARKRAY, Inc. Diluent for preparing analytical sample
EP2490020A1 (en) * 2011-02-18 2012-08-22 Koninklijke Philips Electronics N.V. Measurement chip, microfluidic device and method of measurement chip manufacture
JP6571444B2 (ja) * 2014-09-11 2019-09-04 アークレイ株式会社 分析方法、分析チップおよび分析システム
EP3093656A1 (en) * 2015-05-13 2016-11-16 ARKRAY, Inc. Analytical tool and analytical system
JP6846324B2 (ja) * 2016-10-27 2021-03-24 アークレイ株式会社 分析方法及び分析システム
JP6871129B2 (ja) * 2017-10-23 2021-05-12 アークレイ株式会社 分析方法
JP7262645B2 (ja) * 2018-08-23 2023-04-21 アークレイ株式会社 成分分析方法及び成分分析装置
JP7085943B2 (ja) * 2018-08-23 2022-06-17 アークレイ株式会社 成分分析方法及び成分分析装置
US11396809B2 (en) 2018-11-16 2022-07-26 Halliburton Energy Services, Inc. In-situ reservoir fluid analysis system
JP7384752B2 (ja) * 2019-06-21 2023-11-21 アークレイ株式会社 検体成分の分離分析方法
EP4109074A1 (en) * 2020-02-20 2022-12-28 NOK Corporation Particle analysis device
CN117907408B (zh) * 2024-03-18 2024-06-25 深圳市真迈生物科技有限公司 一种芯片、芯片转移装置和分析系统

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JP2790067B2 (ja) 1994-12-27 1998-08-27 株式会社島津製作所 電気泳動装置
JP2007108181A (ja) * 1996-06-28 2007-04-26 Caliper Life Sciences Inc 電子ピペッタおよび電気泳動バイアスのための補償手段
JP2005077293A (ja) * 2003-09-02 2005-03-24 Hitachi Ltd キャピラリ電気泳動装置
JP2005207860A (ja) * 2004-01-22 2005-08-04 Fuji Electric Systems Co Ltd 血液分析装置用チップの製造方法
WO2005106448A1 (ja) * 2004-04-28 2005-11-10 Arkray, Inc. 電気泳動チップおよびこれを備えた電気泳動装置

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Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012515927A (ja) * 2009-01-23 2012-07-12 ドレクセル・ユニバーシティー 炎症を検出するための量子ドットを用いた装置および方法
EP2352020A2 (en) 2010-01-19 2011-08-03 Arkray, Inc. Method for analyzing sample by electrophoresis and use of the same
JP2011169892A (ja) * 2010-01-19 2011-09-01 Arkray Inc 電気泳動を用いた試料の分析方法及びその利用
EP2352020A3 (en) * 2010-01-19 2013-04-24 Arkray, Inc. Method for analyzing sample by electrophoresis and use of the same
WO2012017515A1 (ja) * 2010-08-03 2012-02-09 ミライアル株式会社 マイクロ流路デバイス
EP2420844A1 (en) 2010-08-16 2012-02-22 Arkray, Inc. Analytical method of hemoglobin
US8420399B2 (en) 2010-08-16 2013-04-16 Arkray, Inc. Analytical method of hemoglobin
JP2013117522A (ja) * 2011-10-31 2013-06-13 Arkray Inc 基材の修飾方法
EP2993467A1 (en) 2014-09-04 2016-03-09 ARKRAY, Inc. Analysis method and analysis system
US10018589B2 (en) 2014-09-04 2018-07-10 Arkray, Inc. Analysis method and analysis system
EP2998732A1 (en) 2014-09-11 2016-03-23 ARKRAY, Inc. Analysis method, analysis chip, and analysis system
US9983170B2 (en) 2014-09-11 2018-05-29 Arkray, Inc. Analysis method, analysis chip, and analysis system
EP3179243A1 (en) 2015-12-09 2017-06-14 ARKRAY, Inc. Analytical tool for capillary electrophoresis with pressure fluctuation reducer
JP2017106904A (ja) * 2015-12-09 2017-06-15 アークレイ株式会社 分析用具および分析システム
US11187674B2 (en) 2015-12-09 2021-11-30 Arkray, Inc. Analytical tool and analytical system
EP3438654A2 (en) 2017-08-03 2019-02-06 ARKRAY, Inc. Analysis chip
EP3608663A1 (en) 2018-08-08 2020-02-12 ARKRAY, Inc. Analysis chip device
US11513096B2 (en) 2018-08-08 2022-11-29 Arkray, Inc. Analysis chip device

Also Published As

Publication number Publication date
US20100116660A1 (en) 2010-05-13
JP5584842B2 (ja) 2014-09-03
EP2148193A4 (en) 2010-08-18
JPWO2008136465A1 (ja) 2010-07-29
JP2014134556A (ja) 2014-07-24
EP2148193A1 (en) 2010-01-27
EP2803992B1 (en) 2021-02-17
EP2803992A1 (en) 2014-11-19
CN101568830B (zh) 2013-05-22
US9494553B2 (en) 2016-11-15
JP5559967B2 (ja) 2014-07-23
CN101568830A (zh) 2009-10-28
WO2008136465A8 (ja) 2009-03-12
JP2014170017A (ja) 2014-09-18
JP5632556B2 (ja) 2014-11-26

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