WO2008133141A1 - オスモチン組換えタンパク質およびその製造方法、並びにその利用 - Google Patents

オスモチン組換えタンパク質およびその製造方法、並びにその利用 Download PDF

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Publication number
WO2008133141A1
WO2008133141A1 PCT/JP2008/057430 JP2008057430W WO2008133141A1 WO 2008133141 A1 WO2008133141 A1 WO 2008133141A1 JP 2008057430 W JP2008057430 W JP 2008057430W WO 2008133141 A1 WO2008133141 A1 WO 2008133141A1
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osmotin
same
recombinant protein
production
produced
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PCT/JP2008/057430
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English (en)
French (fr)
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Kanako Kobayashi
Hiroaki Nishiguchi
Takashi Kadowaki
Toshimasa Yamauchi
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Toyo Boseki Kabushiki Kaisha
The University Of Tokyo
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Priority to JP2009511825A priority Critical patent/JPWO2008133141A1/ja
Publication of WO2008133141A1 publication Critical patent/WO2008133141A1/ja

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Abstract

　オスモチンまたはその変異体をコードするポリヌクレオチドが発現可能に導入された非植物形質転換体を用いて、オスモチン組換えタンパク質を製造する。これにより、本発明は、簡便に、しかも安価かつ大量に取得可能で、生理活性を有するオスモチン組換えタンパク質およびその製造方法、並びにその利用を提供する。
PCT/JP2008/057430 2007-04-24 2008-04-16 オスモチン組換えタンパク質およびその製造方法、並びにその利用 WO2008133141A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009511825A JPWO2008133141A1 (ja) 2007-04-24 2008-04-16 オスモチン組換えタンパク質およびその製造方法、並びにその利用

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007114795 2007-04-24
JP2007-114795 2007-04-24

Publications (1)

Publication Number Publication Date
WO2008133141A1 true WO2008133141A1 (ja) 2008-11-06

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ID=39925597

Family Applications (1)

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PCT/JP2008/057430 WO2008133141A1 (ja) 2007-04-24 2008-04-16 オスモチン組換えタンパク質およびその製造方法、並びにその利用

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JP (1) JPWO2008133141A1 (ja)
WO (1) WO2008133141A1 (ja)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011148715A (ja) * 2010-01-19 2011-08-04 Maruzen Pharmaceut Co Ltd タンパク質のカルボニル化抑制剤及び肌の透明感向上剤
WO2012057343A1 (ja) * 2010-10-28 2012-05-03 国立大学法人九州大学 Ｎａｄ（ｐ）ｈオキシダーゼ阻害剤、酸化ストレス疾患治療薬、酸化ストレス疾患治療方法及びスクリーニング方法
JP2013213688A (ja) * 2012-03-30 2013-10-17 Kanagawa Academy Of Science And Technology 高脂血症又は糖尿病の検出方法及び疾患の治療剤のスクリーニング方法
KR101735057B1 (ko) 2015-06-23 2017-05-12 경상대학교산학협력단 오스모틴 단백질 또는 오스모틴 펩타이드를 유효성분으로 함유하는 간기능 및 신장기능 장애의 예방 또는 치료용 조성물
KR101768869B1 (ko) 2015-03-04 2017-08-18 경상대학교산학협력단 오스모틴 펩티드를 유효성분으로 함유하는 신경질환의 예방, 개선 또는 치료용 조성물
WO2017150916A1 (ko) * 2016-03-04 2017-09-08 에치비아이주식회사 재조합 단백질의 가용화를 위한 조성물, 그 방법 및 이를 이용한 재조합 항원의 생산 방법

Citations (2)

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JP2005220121A (ja) * 2004-01-05 2005-08-18 National Institute Of Advanced Industrial & Technology タンパク質巻き戻し材料
WO2006036871A2 (en) * 2004-09-27 2006-04-06 Purdue Research Foundation Plant pr-5 proteins as mammalian therapeutic agents

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JP2005220121A (ja) * 2004-01-05 2005-08-18 National Institute Of Advanced Industrial & Technology タンパク質巻き戻し材料
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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011148715A (ja) * 2010-01-19 2011-08-04 Maruzen Pharmaceut Co Ltd タンパク質のカルボニル化抑制剤及び肌の透明感向上剤
WO2012057343A1 (ja) * 2010-10-28 2012-05-03 国立大学法人九州大学 Ｎａｄ（ｐ）ｈオキシダーゼ阻害剤、酸化ストレス疾患治療薬、酸化ストレス疾患治療方法及びスクリーニング方法
JP2013213688A (ja) * 2012-03-30 2013-10-17 Kanagawa Academy Of Science And Technology 高脂血症又は糖尿病の検出方法及び疾患の治療剤のスクリーニング方法
KR101768869B1 (ko) 2015-03-04 2017-08-18 경상대학교산학협력단 오스모틴 펩티드를 유효성분으로 함유하는 신경질환의 예방, 개선 또는 치료용 조성물
KR101735057B1 (ko) 2015-06-23 2017-05-12 경상대학교산학협력단 오스모틴 단백질 또는 오스모틴 펩타이드를 유효성분으로 함유하는 간기능 및 신장기능 장애의 예방 또는 치료용 조성물
WO2017150916A1 (ko) * 2016-03-04 2017-09-08 에치비아이주식회사 재조합 단백질의 가용화를 위한 조성물, 그 방법 및 이를 이용한 재조합 항원의 생산 방법

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