WO2008130630A4 - Forme polymorphique de l'hydrochlorure de rimonabant et ses procédés de fabrication - Google Patents

Forme polymorphique de l'hydrochlorure de rimonabant et ses procédés de fabrication Download PDF

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Publication number
WO2008130630A4
WO2008130630A4 PCT/US2008/005022 US2008005022W WO2008130630A4 WO 2008130630 A4 WO2008130630 A4 WO 2008130630A4 US 2008005022 W US2008005022 W US 2008005022W WO 2008130630 A4 WO2008130630 A4 WO 2008130630A4
Authority
WO
WIPO (PCT)
Prior art keywords
rimonabant hydrochloride
crystalline
crystalline rimonabant
hydrochloride
processes
Prior art date
Application number
PCT/US2008/005022
Other languages
English (en)
Other versions
WO2008130630A3 (fr
WO2008130630A2 (fr
Inventor
Eli Lancry
Marina Kalujny
Claude Singer
Sigalit Levi
Michal Rafilovich
Original Assignee
Teva Pharma
Eli Lancry
Marina Kalujny
Claude Singer
Sigalit Levi
Michal Rafilovich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma, Eli Lancry, Marina Kalujny, Claude Singer, Sigalit Levi, Michal Rafilovich filed Critical Teva Pharma
Publication of WO2008130630A2 publication Critical patent/WO2008130630A2/fr
Publication of WO2008130630A3 publication Critical patent/WO2008130630A3/fr
Publication of WO2008130630A4 publication Critical patent/WO2008130630A4/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Addiction (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention a trait à une forme cristalline de l'hydrochlorure de rimonabant, à ses procédés de fabrication et à des compositions pharmaceutiques contenant ladite forme cristalline de l'hydrochlorure de rimonabant.
PCT/US2008/005022 2007-04-16 2008-04-16 Forme polymorphique de l'hydrochlorure de rimonabant et ses procédés de fabrication WO2008130630A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92383007P 2007-04-16 2007-04-16
US60/923,830 2007-04-16

Publications (3)

Publication Number Publication Date
WO2008130630A2 WO2008130630A2 (fr) 2008-10-30
WO2008130630A3 WO2008130630A3 (fr) 2009-02-19
WO2008130630A4 true WO2008130630A4 (fr) 2009-04-16

Family

ID=39666000

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/005022 WO2008130630A2 (fr) 2007-04-16 2008-04-16 Forme polymorphique de l'hydrochlorure de rimonabant et ses procédés de fabrication

Country Status (1)

Country Link
WO (1) WO2008130630A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102206182B (zh) * 2011-04-11 2013-03-13 中国药科大学 盐酸利莫那班的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1844017A1 (fr) * 2005-01-06 2007-10-17 Cadila Healthcare Ltd. Forme amorphe et trois formes cristallines de chlorhydrate de rimonabant
PL2032521T3 (pl) * 2006-06-27 2010-05-31 Sandoz Ag Nowy sposób wytwarzania soli
US20080004313A1 (en) * 2006-06-28 2008-01-03 Mai De Ltd. Preparation of crystalline polymorphs of rimonabant hydrochloride

Also Published As

Publication number Publication date
WO2008130630A3 (fr) 2009-02-19
WO2008130630A2 (fr) 2008-10-30

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