WO2008130025A1 - Hepatocyte culture container and hepatocyte culture method - Google Patents
Hepatocyte culture container and hepatocyte culture method Download PDFInfo
- Publication number
- WO2008130025A1 WO2008130025A1 PCT/JP2008/057573 JP2008057573W WO2008130025A1 WO 2008130025 A1 WO2008130025 A1 WO 2008130025A1 JP 2008057573 W JP2008057573 W JP 2008057573W WO 2008130025 A1 WO2008130025 A1 WO 2008130025A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hepatocyte culture
- microcontainers
- culture container
- container
- hepatocyte
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/12—Well or multiwell plates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/16—Microfluidic devices; Capillary tubes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/067—Hepatocytes
Abstract
It is intended to provide a hepatocyte culture container and a hepatocyte culture method capable of reproducing liver function in the living body. A hepatocyte culture container 10 according to the invention is a hepatocyte culture container 10 having a plurality of microcontainers 11 on the surface, and the bottom area of each of the microcontainers 11 is from 0.01 to 0.1 mm2, and the height of a side wall 13 constituting each of the microcontainers 11 is from 25 to 150 μm. Further, the shape of the bottom of each of the microcontainers 11 is isotropic and the major axis thereof is preferably in the range of 1 to 1.5 times ofthe minor axis thereof.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009510862A JPWO2008130025A1 (en) | 2007-04-18 | 2008-04-18 | Hepatocyte culture vessel and hepatocyte culture method |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007-109183 | 2007-04-18 | ||
JP2007109183 | 2007-04-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008130025A1 true WO2008130025A1 (en) | 2008-10-30 |
Family
ID=39875547
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/057573 WO2008130025A1 (en) | 2007-04-18 | 2008-04-18 | Hepatocyte culture container and hepatocyte culture method |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPWO2008130025A1 (en) |
WO (1) | WO2008130025A1 (en) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009099153A1 (en) * | 2008-02-06 | 2009-08-13 | National University Corporation Nagoya University | Cell culture method |
WO2009099152A1 (en) | 2008-02-06 | 2009-08-13 | Public University Corporation Yokohama City University | Cell culture method and screening method |
WO2010047133A1 (en) * | 2008-10-24 | 2010-04-29 | 株式会社クラレ | Cell storage method and cell transport method |
JP2010200679A (en) * | 2009-03-04 | 2010-09-16 | Kuraray Co Ltd | Cell culture container, method for performing cell culture, and method for evaluating cell |
JP2012249547A (en) * | 2011-05-31 | 2012-12-20 | Oji Holdings Corp | Cell culture substrate and method for manufacturing the same |
WO2014196204A1 (en) * | 2013-06-07 | 2014-12-11 | 株式会社クラレ | Culture vessel and culture method |
WO2015182159A1 (en) * | 2014-05-30 | 2015-12-03 | 株式会社クラレ | Culture method and cell mass |
WO2018003858A1 (en) | 2016-06-28 | 2018-01-04 | 国立研究開発法人農業・食品産業技術総合研究機構 | Cell enclosure device and use for same |
WO2018135252A1 (en) | 2017-01-18 | 2018-07-26 | 国立研究開発法人農業・食品産業技術総合研究機構 | Semipermeable membrane and uses thereof |
WO2019116699A1 (en) | 2017-12-12 | 2019-06-20 | 国立研究開発法人農業・食品産業技術総合研究機構 | Cell encapsulation device with suction tube and use thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004154027A (en) * | 2002-11-05 | 2004-06-03 | Foundation For The Promotion Of Industrial Science | Cell culture chamber |
JP2006050975A (en) * | 2004-08-12 | 2006-02-23 | Kuraray Co Ltd | Substrate for operating cell and irrigation flow culture apparatus using the same |
JP2006191809A (en) * | 2005-01-11 | 2006-07-27 | Kuraray Co Ltd | Method for culturing cell with controlled extending direction |
JP2006217845A (en) * | 2005-02-09 | 2006-08-24 | Hitachi Medical Corp | Method and apparatus for culturing adsorptive cell |
-
2008
- 2008-04-18 JP JP2009510862A patent/JPWO2008130025A1/en active Pending
- 2008-04-18 WO PCT/JP2008/057573 patent/WO2008130025A1/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004154027A (en) * | 2002-11-05 | 2004-06-03 | Foundation For The Promotion Of Industrial Science | Cell culture chamber |
JP2006050975A (en) * | 2004-08-12 | 2006-02-23 | Kuraray Co Ltd | Substrate for operating cell and irrigation flow culture apparatus using the same |
JP2006191809A (en) * | 2005-01-11 | 2006-07-27 | Kuraray Co Ltd | Method for culturing cell with controlled extending direction |
JP2006217845A (en) * | 2005-02-09 | 2006-08-24 | Hitachi Medical Corp | Method and apparatus for culturing adsorptive cell |
Cited By (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5940758B2 (en) * | 2008-02-06 | 2016-06-29 | 国立大学法人名古屋大学 | Cell culture method |
WO2009099152A1 (en) | 2008-02-06 | 2009-08-13 | Public University Corporation Yokohama City University | Cell culture method and screening method |
JPWO2009099153A1 (en) * | 2008-02-06 | 2011-05-26 | 国立大学法人名古屋大学 | Cell culture method |
JPWO2009099152A1 (en) * | 2008-02-06 | 2011-05-26 | 公立大学法人横浜市立大学 | Cell culture method and screening method |
WO2009099153A1 (en) * | 2008-02-06 | 2009-08-13 | National University Corporation Nagoya University | Cell culture method |
US9428721B2 (en) | 2008-02-06 | 2016-08-30 | Public University Corporation Yokohama City University | Cell culture of fetal liver in layered state in a partitioned micro-space |
JP5932206B2 (en) * | 2008-02-06 | 2016-06-08 | 公立大学法人横浜市立大学 | Cell culture method and screening method |
WO2010047133A1 (en) * | 2008-10-24 | 2010-04-29 | 株式会社クラレ | Cell storage method and cell transport method |
JP2010200679A (en) * | 2009-03-04 | 2010-09-16 | Kuraray Co Ltd | Cell culture container, method for performing cell culture, and method for evaluating cell |
JP2012249547A (en) * | 2011-05-31 | 2012-12-20 | Oji Holdings Corp | Cell culture substrate and method for manufacturing the same |
US10494593B2 (en) | 2013-06-07 | 2019-12-03 | Corning Incorporated | Culture chamber and culture method |
JP2021129590A (en) * | 2013-06-07 | 2021-09-09 | コーニング インコーポレイテッド | Culture method |
US11866682B1 (en) | 2013-06-07 | 2024-01-09 | Corning Incorporated | Culture chamber and culture method |
JPWO2014196204A1 (en) * | 2013-06-07 | 2017-02-23 | 株式会社クラレ | Culture container and culture method |
JP7219303B2 (en) | 2013-06-07 | 2023-02-07 | コーニング インコーポレイテッド | Culture method |
US11473046B2 (en) | 2013-06-07 | 2022-10-18 | Corning Incorporated | Culture chamber and culture method |
JP2020000255A (en) * | 2013-06-07 | 2020-01-09 | コーニング インコーポレイテッド | Culture chamber and culture method |
WO2014196204A1 (en) * | 2013-06-07 | 2014-12-11 | 株式会社クラレ | Culture vessel and culture method |
JP7125717B2 (en) | 2014-05-30 | 2022-08-25 | コーニング インコーポレイテッド | Culture method |
CN106459925A (en) * | 2014-05-30 | 2017-02-22 | 株式会社可乐丽 | Culture method and cell mass |
JP2019193666A (en) * | 2014-05-30 | 2019-11-07 | コーニング インコーポレイテッド | Culture method |
JPWO2015182159A1 (en) * | 2014-05-30 | 2017-04-20 | 株式会社クラレ | Culture method and cell mass |
CN106459925B (en) * | 2014-05-30 | 2019-12-27 | 株式会社可乐丽 | Culture method and cell pellet |
US20170183621A1 (en) * | 2014-05-30 | 2017-06-29 | Kuraray Co., Ltd. | Culture method and cell cluster |
US10752879B2 (en) | 2014-05-30 | 2020-08-25 | Corning Incorporated | Culture method and cell cluster |
WO2015182159A1 (en) * | 2014-05-30 | 2015-12-03 | 株式会社クラレ | Culture method and cell mass |
WO2018003858A1 (en) | 2016-06-28 | 2018-01-04 | 国立研究開発法人農業・食品産業技術総合研究機構 | Cell enclosure device and use for same |
WO2018135252A1 (en) | 2017-01-18 | 2018-07-26 | 国立研究開発法人農業・食品産業技術総合研究機構 | Semipermeable membrane and uses thereof |
KR20190104159A (en) | 2017-01-18 | 2019-09-06 | 고쿠리츠겐큐가이하츠호징 노우교 · 쇼쿠힝 산교기쥬츠 소고겐큐기코 | Semi-permeable membrane and its use |
KR20200079540A (en) | 2017-12-12 | 2020-07-03 | 고쿠리츠겐큐가이하츠호징 노우교 · 쇼쿠힝 산교기쥬츠 소고겐큐기코 | Cell encapsulation device with suction tube and use thereof |
WO2019116699A1 (en) | 2017-12-12 | 2019-06-20 | 国立研究開発法人農業・食品産業技術総合研究機構 | Cell encapsulation device with suction tube and use thereof |
Also Published As
Publication number | Publication date |
---|---|
JPWO2008130025A1 (en) | 2010-07-22 |
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