WO2008123508A1 - 受精卵の培養方法及び受精卵の培養装置 - Google Patents

受精卵の培養方法及び受精卵の培養装置 Download PDF

Info

Publication number
WO2008123508A1
WO2008123508A1 PCT/JP2008/056375 JP2008056375W WO2008123508A1 WO 2008123508 A1 WO2008123508 A1 WO 2008123508A1 JP 2008056375 W JP2008056375 W JP 2008056375W WO 2008123508 A1 WO2008123508 A1 WO 2008123508A1
Authority
WO
WIPO (PCT)
Prior art keywords
fertilized egg
channel
incubator
incubating
incubating fertilized
Prior art date
Application number
PCT/JP2008/056375
Other languages
English (en)
French (fr)
Inventor
Keiji Naruse
Norio Ishida
Original Assignee
Strex Incorporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Strex Incorporation filed Critical Strex Incorporation
Publication of WO2008123508A1 publication Critical patent/WO2008123508A1/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0604—Whole embryos; Culture medium therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/06—Bioreactors or fermenters specially adapted for specific uses for in vitro fertilization
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/04—Flat or tray type, drawers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/24—Gas permeable parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Developmental Biology & Embryology (AREA)
  • Clinical Laboratory Science (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mechanical Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

　受精卵の効率的な培養方法および培養装置を提供すること。培養器１の閉じられたチャネル２へ培養液９と受精卵８を充填し、該培養器１を傾斜若しくは回転させることにより受精卵８をチャネル２内で移動させる。培養器を酸素透過性のシリコンハイドロゲルで形成し、培養器１をチャネル２の軸方向へ、あるいはチャネル近傍を圧縮することによりチャネル２を繰り返し変形させてチャネル２内の受精卵８へ物理的な刺激を与える。
PCT/JP2008/056375 2007-03-30 2008-03-31 受精卵の培養方法及び受精卵の培養装置 WO2008123508A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007091036 2007-03-30
JP2007-091036 2007-03-30

Publications (1)

Publication Number Publication Date
WO2008123508A1 true WO2008123508A1 (ja) 2008-10-16

Family

ID=39830985

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/056375 WO2008123508A1 (ja) 2007-03-30 2008-03-31 受精卵の培養方法及び受精卵の培養装置

Country Status (2)

Country Link
JP (1) JP5370882B2 (ja)
WO (1) WO2008123508A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011044872A1 (de) * 2009-10-14 2011-04-21 Forschungszentrum Jülich GmbH Vorrichtung zur untersuchung von zellen mit einem elastomer sowie verwendung der vorrichtung
US9617507B2 (en) 2012-10-24 2017-04-11 IonOptix LLC Apparatus and method for culturing cells and tissue
PL422205A1 (pl) * 2017-07-13 2019-01-14 Falkowski Andrzej Gospodarstwo Rybackie Falko Aparat słojowy do inkubacji ikry

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101935167B1 (ko) * 2017-09-15 2019-01-03 계명대학교 산학협력단 난관을 모사한 수정란 배양장치의 제조방법
KR101961025B1 (ko) * 2017-09-15 2019-03-21 계명대학교 산학협력단 수정란 배양장치의 미세패턴 형성방법
WO2019054835A2 (ko) * 2017-09-15 2019-03-21 계명대학교 산학협력단 난관을 모사한 수정란 배양장치 및 그 수정란 배양장치의 제조방법
KR102005807B1 (ko) * 2018-06-25 2019-07-31 단국대학교 산학협력단 난자 성장 장치 및 이를 이용한 난자 성장 방법

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0343327U (ja) * 1989-08-30 1991-04-23
JP2004113222A (ja) * 2002-09-24 2004-04-15 Kenji Kashiwagi 生体細胞又は組織の加重培養方法および装置
WO2005087913A1 (ja) * 2004-03-11 2005-09-22 Nagoya Industrial Science Research Institute 培養器
WO2005090548A1 (ja) * 2004-03-19 2005-09-29 Nagoya Industrial Science Research Institute 培養器用保持装置
JP2006212017A (ja) * 2005-02-03 2006-08-17 Otake:Kk 回転荷重加圧培養装置
JP2007075090A (ja) * 2005-09-13 2007-03-29 Otake:Kk 旋回培養装置
WO2007052653A1 (ja) * 2005-10-31 2007-05-10 Strex Incorporation 培養容器および培養装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006320304A (ja) * 2005-05-18 2006-11-30 Cellseed Inc 密閉系細胞培養容器及びそれを利用した細胞培養方法
JP2007068447A (ja) * 2005-09-06 2007-03-22 Hiroshima Univ 幹細胞の培養方法及び幹細胞
JP2007074921A (ja) * 2005-09-12 2007-03-29 Hitachi Medical Corp 細胞培養装置
WO2007123035A1 (ja) * 2006-04-18 2007-11-01 Strex Incorporation 培養器
JP3139350U (ja) * 2007-11-27 2008-02-14 株式会社クラレ 細胞培養容器
JP5148397B2 (ja) * 2008-07-18 2013-02-20 株式会社クラレ 細胞培養容器および細胞培養方法

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0343327U (ja) * 1989-08-30 1991-04-23
JP2004113222A (ja) * 2002-09-24 2004-04-15 Kenji Kashiwagi 生体細胞又は組織の加重培養方法および装置
WO2005087913A1 (ja) * 2004-03-11 2005-09-22 Nagoya Industrial Science Research Institute 培養器
WO2005090548A1 (ja) * 2004-03-19 2005-09-29 Nagoya Industrial Science Research Institute 培養器用保持装置
JP2006212017A (ja) * 2005-02-03 2006-08-17 Otake:Kk 回転荷重加圧培養装置
JP2007075090A (ja) * 2005-09-13 2007-03-29 Otake:Kk 旋回培養装置
WO2007052653A1 (ja) * 2005-10-31 2007-05-10 Strex Incorporation 培養容器および培養装置

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BROWN T.D.: "Techniques for mechanical stimulation of cells in vitro: a review", J. BIOMECH., vol. 33, 2000, pages 3 - 14 *
MIZUNO J. ET AL.: "O-187 Stretch-stimulated endometrial cells/embryo co-culture system for human Assited Reproductive Technology (ART)", FERTILITY AND STERILITY, vol. 86, no. 3, SUPPL. 2, September 2006 (2006-09-01), pages S80 + ABSTR. NO. O-187 *
SOKABE M. ET AL.: "Baiyo Saibo eno Kakushu Shinten Shigekibo -Sono Riten to Ketten- (METHODS OF TRETCHING CULTURED CELLS: THEIR ADVANTAGES AND DISADVANTAGES)", THE TISSUE CULTURE, vol. 22, no. 10, 1 January 1996 (1996-01-01), pages 413 - 417, XP002997615 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011044872A1 (de) * 2009-10-14 2011-04-21 Forschungszentrum Jülich GmbH Vorrichtung zur untersuchung von zellen mit einem elastomer sowie verwendung der vorrichtung
US9617507B2 (en) 2012-10-24 2017-04-11 IonOptix LLC Apparatus and method for culturing cells and tissue
US10421955B2 (en) 2012-10-24 2019-09-24 IonOptix LLC Apparatus and method for culturing cells and tissue
PL422205A1 (pl) * 2017-07-13 2019-01-14 Falkowski Andrzej Gospodarstwo Rybackie Falko Aparat słojowy do inkubacji ikry

Also Published As

Publication number Publication date
JP5370882B2 (ja) 2013-12-18
JP2008271964A (ja) 2008-11-13

Similar Documents

Publication Publication Date Title
WO2008123508A1 (ja) 受精卵の培養方法及び受精卵の培養装置
EP2016166A4 (en) DEVICE AND METHOD FOR CULTIVATING BIOLOGICAL ORGANISMS FOR THE PRODUCTION OF FUELS, AMONG OTHER
WO2008036447A3 (en) Pluripotent stem cell culture
BRPI0619794B8 (pt) Uso de um fator de reprogramação, agente para a preparação de uma célula-tronco pluripotente induzida a partir de uma célula somática e métodos para preparar uma célula- tronco pluripotente induzida método e para preparar uma célula somática e uso de células-tronco pluripotentes induzidas
AR073378A1 (es) Aparato, metodo y sistema de plantacion automatizados para investigacion
GB2446525A (en) Stem cell culture medium and method
EP2410044A3 (en) Stem cells culture systems
WO2008013967A8 (en) Continuous culture apparatus with mobile vessel and producing a culture in a continuous manner
BRPI0502195A (pt) método para fabricar uma semente artificial, e, sistema de manuseio de material
MY164305A (en) Method and apparatus for treatment of organic waste
WO2012009682A3 (en) Elastic substrates and methods of use in cell manipulation and culture
TN2010000112A1 (en) Method for harvesting algae or plants and device used thereby
MD20070255A (ro) Procedeu şi instalaţie pentru prelucrarea unui produs vegetal, dispozitiv cu supapă pentru instalaţia menţionată, utilizare a instalaţiei şi dispozitivului cu supapă pentru realizarea procedeului indicat
WO2007096417A3 (en) Method for incubation and hatching of eggs
FR2927906B1 (fr) Procede et dispositif de culture cellulaire en mode continu ouvert.
WO2012092542A3 (en) Responsive cell culture hydrogel
WO2006058078A3 (en) Cytoblock preparation system and methods of use
ATE513296T1 (de) Verfahren und vorrichtung zur impliziten dram- vorladung
DE602007007944D1 (de) Vorrichtung zur kultivierung von zellen oder mikroorganismen
AU2003282090A1 (en) Sampling valve and method for the sterile taking of samples from fermenters or bioreactors by means of said sampling valve
WO2008140046A1 (ja) 生体組織分解方法
WO2004033616A8 (de) Einrichtung zur kultivierung von zellen, insbesondere menschlicher oder tierischer zellen
WO2007054537A8 (en) Novel bacterium and vaccine
IL179318A0 (en) Methods and devices for culturing stem cells
WO2008132861A1 (ja) 培養用容器、細胞又は組織の培養方法、及び細胞又は組織の解析方法

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08739488

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08739488

Country of ref document: EP

Kind code of ref document: A1