WO2008114458A1 - Puce pour trieur de cellules et trieur de cellules - Google Patents
Puce pour trieur de cellules et trieur de cellules Download PDFInfo
- Publication number
- WO2008114458A1 WO2008114458A1 PCT/JP2007/056121 JP2007056121W WO2008114458A1 WO 2008114458 A1 WO2008114458 A1 WO 2008114458A1 JP 2007056121 W JP2007056121 W JP 2007056121W WO 2008114458 A1 WO2008114458 A1 WO 2008114458A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cells
- flow path
- cell
- region
- cell identification
- Prior art date
Links
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1468—Electro-optical investigation, e.g. flow cytometers with spatial resolution of the texture or inner structure of the particle
- G01N15/147—Electro-optical investigation, e.g. flow cytometers with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
-
- G01N15/149—
Abstract
Cette invention se rapporte à une puce pour trieur de cellules et à un trieur de cellules qui exécute la séparation et l'analyse de chaque cellule individuelle, et exécute la séparation et la récupération de chacune de ces cellules. Des mesures comparatives peuvent ainsi être effectuées, et porter sur des états métaboliques des cellules, des variations des réponses cellulaires après stimulation pharmacologique, etc. Par ailleurs, la séparation cellulaire basée sur les mesures comparatives permet d'obtenir une purification précise des cellules en fonction de leur phénotype. En outre, les mesures comparatives portant sur les états métaboliques des cellules, les variations des réponses des cellules après leur stimulation, etc. peuvent être effectuées en prenant des clichés instantanés des cellules passant par un canal d'écoulement au moins deux fois à un intervalle de temps donné et en mesurant la quantité de variation dans les cellules (par exemple, la vitesse de métabolisme) se produisant entre deux clichés instantanés. La séparation cellulaire peut être effectuée à partir des résultats obtenus lors des mesures comparatives.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP2007/056121 WO2008114458A1 (fr) | 2007-03-16 | 2007-03-16 | Puce pour trieur de cellules et trieur de cellules |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP2007/056121 WO2008114458A1 (fr) | 2007-03-16 | 2007-03-16 | Puce pour trieur de cellules et trieur de cellules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2008114458A1 true WO2008114458A1 (fr) | 2008-09-25 |
Family
ID=39765579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/JP2007/056121 WO2008114458A1 (fr) | 2007-03-16 | 2007-03-16 | Puce pour trieur de cellules et trieur de cellules |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2008114458A1 (fr) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015212709A (ja) * | 2012-03-30 | 2015-11-26 | ソニー株式会社 | 微小粒子分取装置及び微小粒子分取装置における位置制御方法 |
| JP2017504037A (ja) * | 2013-10-30 | 2017-02-02 | プレミアム ジェネティクス （ユーケー） リミテッド | 集束エネルギー装置を有するマイクロ流体システム及び方法 |
| JP2019179033A (ja) * | 2019-05-08 | 2019-10-17 | エービーエス グローバル インコーポレイテッド | マイクロ流体チップシステム、および、流体混合物内の複数の成分を明らかにする方法 |
| US11187224B2 (en) | 2013-07-16 | 2021-11-30 | Abs Global, Inc. | Microfluidic chip |
| US11193879B2 (en) | 2010-11-16 | 2021-12-07 | 1087 Systems, Inc. | Use of vibrational spectroscopy for microfluidic liquid measurement |
| US11243494B2 (en) | 2002-07-31 | 2022-02-08 | Abs Global, Inc. | Multiple laminar flow-based particle and cellular separation with laser steering |
| US11331670B2 (en) | 2018-05-23 | 2022-05-17 | Abs Global, Inc. | Systems and methods for particle focusing in microchannels |
| US11415503B2 (en) | 2013-10-30 | 2022-08-16 | Abs Global, Inc. | Microfluidic system and method with focused energy apparatus |
| US11628439B2 (en) | 2020-01-13 | 2023-04-18 | Abs Global, Inc. | Single-sheath microfluidic chip |
| US11889830B2 (en) | 2019-04-18 | 2024-02-06 | Abs Global, Inc. | System and process for continuous addition of cryoprotectant |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006220423A (ja) * | 2005-02-08 | 2006-08-24 | Japan Science & Technology Agency | ゲル電極付セルソーターチップ |
| JP2007104929A (ja) * | 2005-10-12 | 2007-04-26 | Japan Science & Technology Agency | セルソーターチップおよびセルソーター |
-
2007
- 2007-03-16 WO PCT/JP2007/056121 patent/WO2008114458A1/fr active Application Filing
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006220423A (ja) * | 2005-02-08 | 2006-08-24 | Japan Science & Technology Agency | ゲル電極付セルソーターチップ |
| JP2007104929A (ja) * | 2005-10-12 | 2007-04-26 | Japan Science & Technology Agency | セルソーターチップおよびセルソーター |
Cited By (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11243494B2 (en) | 2002-07-31 | 2022-02-08 | Abs Global, Inc. | Multiple laminar flow-based particle and cellular separation with laser steering |
| US11422504B2 (en) | 2002-07-31 | 2022-08-23 | Abs Global, Inc. | Multiple laminar flow-based particle and cellular separation with laser steering |
| US11415936B2 (en) | 2002-07-31 | 2022-08-16 | Abs Global, Inc. | Multiple laminar flow-based particle and cellular separation with laser steering |
| US11965816B2 (en) | 2010-11-16 | 2024-04-23 | 1087 Systems, Inc. | Use of vibrational spectroscopy for microfluidic liquid measurement |
| US11193879B2 (en) | 2010-11-16 | 2021-12-07 | 1087 Systems, Inc. | Use of vibrational spectroscopy for microfluidic liquid measurement |
| JP2015212709A (ja) * | 2012-03-30 | 2015-11-26 | ソニー株式会社 | 微小粒子分取装置及び微小粒子分取装置における位置制御方法 |
| US11187224B2 (en) | 2013-07-16 | 2021-11-30 | Abs Global, Inc. | Microfluidic chip |
| US11512691B2 (en) | 2013-07-16 | 2022-11-29 | Abs Global, Inc. | Microfluidic chip |
| US10928298B2 (en) | 2013-10-30 | 2021-02-23 | Abs Global, Inc. | Microfluidic system and method with focused energy apparatus |
| US11415503B2 (en) | 2013-10-30 | 2022-08-16 | Abs Global, Inc. | Microfluidic system and method with focused energy apparatus |
| US11639888B2 (en) | 2013-10-30 | 2023-05-02 | Abs Global, Inc. | Microfluidic system and method with focused energy apparatus |
| US11796449B2 (en) | 2013-10-30 | 2023-10-24 | Abs Global, Inc. | Microfluidic system and method with focused energy apparatus |
| JP2017504037A (ja) * | 2013-10-30 | 2017-02-02 | プレミアム ジェネティクス （ユーケー） リミテッド | 集束エネルギー装置を有するマイクロ流体システム及び方法 |
| US11331670B2 (en) | 2018-05-23 | 2022-05-17 | Abs Global, Inc. | Systems and methods for particle focusing in microchannels |
| US11889830B2 (en) | 2019-04-18 | 2024-02-06 | Abs Global, Inc. | System and process for continuous addition of cryoprotectant |
| JP2019179033A (ja) * | 2019-05-08 | 2019-10-17 | エービーエス グローバル インコーポレイテッド | マイクロ流体チップシステム、および、流体混合物内の複数の成分を明らかにする方法 |
| US11628439B2 (en) | 2020-01-13 | 2023-04-18 | Abs Global, Inc. | Single-sheath microfluidic chip |
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