WO2008084652A1 - 血管内皮細胞結合性ペプチド - Google Patents
血管内皮細胞結合性ペプチド Download PDFInfo
- Publication number
- WO2008084652A1 WO2008084652A1 PCT/JP2007/074640 JP2007074640W WO2008084652A1 WO 2008084652 A1 WO2008084652 A1 WO 2008084652A1 JP 2007074640 W JP2007074640 W JP 2007074640W WO 2008084652 A1 WO2008084652 A1 WO 2008084652A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- peptide
- vascular endothelial
- amino acid
- endothelial cells
- ability
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- 210000003556 vascular endothelial cell Anatomy 0.000 title abstract 3
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 3
- 239000003446 ligand Substances 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 210000002889 endothelial cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07851046A EP2108698A4 (en) | 2007-01-09 | 2007-12-21 | VASCULAR ENDOTHELIAL CELL BINDING PEPTIDE |
US12/521,981 US20100184695A1 (en) | 2007-01-09 | 2007-12-21 | Vascular endothelial cell-binding peptide |
JP2008509849A JPWO2008084652A1 (ja) | 2007-01-09 | 2007-12-21 | 血管内皮細胞結合性ペプチド |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007-001294 | 2007-01-09 | ||
JP2007001294 | 2007-01-09 | ||
JP2007-232443 | 2007-09-07 | ||
JP2007232443 | 2007-09-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008084652A1 true WO2008084652A1 (ja) | 2008-07-17 |
Family
ID=39608549
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2007/074640 WO2008084652A1 (ja) | 2007-01-09 | 2007-12-21 | 血管内皮細胞結合性ペプチド |
Country Status (4)
Country | Link |
---|---|
US (1) | US20100184695A1 (ja) |
EP (1) | EP2108698A4 (ja) |
JP (1) | JPWO2008084652A1 (ja) |
WO (1) | WO2008084652A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012524904A (ja) * | 2009-04-21 | 2012-10-18 | ユニバーシティ オブ ユタ リサーチ ファウンデーション | 手術時イメージングまたはセンチネルリンパ節バイオプシー用の発光ダイ |
JP2017524380A (ja) * | 2014-07-08 | 2017-08-31 | 北京▲華▼安科▲創▼生物技▲術▼有限公司Beijing Hua’An Innovation Biotechnology Co., Ltd. | 腫瘍血管遮断剤であるポリペプチド、遺伝子、発現ベクター、及びその使用方法 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9198975B2 (en) | 2010-12-01 | 2015-12-01 | The University Of North Carolina At Chapel Hill | Methods and compositions for targeting sites of neovascular growth |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6881825B1 (en) * | 1999-09-01 | 2005-04-19 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Identication of peptides that facilitate uptake and cytoplasmic and/or nuclear transport of proteins, DNA and virues |
US7420030B2 (en) * | 2000-09-08 | 2008-09-02 | The Board Of Regents Of The University Of Texas System | Aminopeptidase A (APA) targeting peptides for the treatment of cancer |
-
2007
- 2007-12-21 WO PCT/JP2007/074640 patent/WO2008084652A1/ja active Application Filing
- 2007-12-21 EP EP07851046A patent/EP2108698A4/en not_active Withdrawn
- 2007-12-21 JP JP2008509849A patent/JPWO2008084652A1/ja active Pending
- 2007-12-21 US US12/521,981 patent/US20100184695A1/en not_active Abandoned
Non-Patent Citations (5)
Title |
---|
ARAP W. ET AL.: "Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model", SCIENCE, vol. 279, no. 5349, 1998, pages 377 - 380, XP000857470 * |
ARAP WADIH; 2 OTHERS: "Cancer Treatment of Targeted Drug Delivery to Tumor Vasculature in a Mouse Model", SCIENCE, vol. 279, 1998, pages 377 - 380 |
HERBERT HURVITZ; 14 OTHERS: "Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer", NEW ENGL J MED, vol. 350, 2004, pages 2335 - 2342, XP002302382 |
LIANG S. ET AL.: "Screening and identification of vascular-endothelial-cell-specific binding peptide in gastric cancer", J. MOL. MED., vol. 84, no. 9, 2006, pages 764 - 773, XP019401156 * |
MUTUVERRIA R. ET AL.: "Isolation of human antibodies to tumor-associated endothelial cell markers by in vitro human endothelial cell selection with phage display libraries", J. IMMUNOL. METHODS, vol. 287, no. 1-2, 2004, pages 31 - 47, XP004503468 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012524904A (ja) * | 2009-04-21 | 2012-10-18 | ユニバーシティ オブ ユタ リサーチ ファウンデーション | 手術時イメージングまたはセンチネルリンパ節バイオプシー用の発光ダイ |
JP2015178002A (ja) * | 2009-04-21 | 2015-10-08 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション | 手術時イメージングまたはセンチネルリンパ節バイオプシー用の発光ダイ |
JP2017524380A (ja) * | 2014-07-08 | 2017-08-31 | 北京▲華▼安科▲創▼生物技▲術▼有限公司Beijing Hua’An Innovation Biotechnology Co., Ltd. | 腫瘍血管遮断剤であるポリペプチド、遺伝子、発現ベクター、及びその使用方法 |
Also Published As
Publication number | Publication date |
---|---|
EP2108698A1 (en) | 2009-10-14 |
EP2108698A4 (en) | 2010-03-17 |
JPWO2008084652A1 (ja) | 2010-04-30 |
US20100184695A1 (en) | 2010-07-22 |
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