WO2008084574A1 - 血管新生阻害剤 - Google Patents

血管新生阻害剤 Download PDF

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Publication number
WO2008084574A1
WO2008084574A1 PCT/JP2007/067173 JP2007067173W WO2008084574A1 WO 2008084574 A1 WO2008084574 A1 WO 2008084574A1 JP 2007067173 W JP2007067173 W JP 2007067173W WO 2008084574 A1 WO2008084574 A1 WO 2008084574A1
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WO
WIPO (PCT)
Prior art keywords
composition
disclosed
angiogenic activity
angiogenic agent
angiogenic
Prior art date
Application number
PCT/JP2007/067173
Other languages
English (en)
French (fr)
Inventor
Kyosuke Yamamoto
Takashi Kimura
Original Assignee
Unitika Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unitika Ltd. filed Critical Unitika Ltd.
Priority to JP2008553003A priority Critical patent/JPWO2008084574A1/ja
Publication of WO2008084574A1 publication Critical patent/WO2008084574A1/ja

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Botany (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)

Abstract

　長期間摂取し続けても安全で、かつ経口投与でも血管新生に伴う疾病を予防または治療する効果を充分に発揮する血管新生阻害活性を有する組成物並びにそれを含有する血管新生阻害剤及び血管新生阻害効果を有する飲食品を提供する。 　ハナビラタケの子実体及び／又は菌糸体に由来するβ－グルカン又はβ－グルカン含有物を含むことを特徴とする血管新生阻害活性を有する組成物。
PCT/JP2007/067173 2006-12-25 2007-09-04 血管新生阻害剤 WO2008084574A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2008553003A JPWO2008084574A1 (ja) 2006-12-25 2007-09-04 血管新生阻害剤

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006347695 2006-12-25
JP2006-347695 2006-12-25

Publications (1)

Publication Number Publication Date
WO2008084574A1 true WO2008084574A1 (ja) 2008-07-17

Family

ID=39608472

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/067173 WO2008084574A1 (ja) 2006-12-25 2007-09-04 血管新生阻害剤

Country Status (2)

Country Link
JP (1) JPWO2008084574A1 (ja)
WO (1) WO2008084574A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010059106A (ja) * 2008-09-04 2010-03-18 Unitika Ltd 糖尿病進行抑制作用を有する組成物
JP2010100576A (ja) * 2008-10-24 2010-05-06 Unitika Ltd 便秘改善剤
JP2014001188A (ja) * 2012-06-20 2014-01-09 Hiroko Ito 血管新生阻害剤及び血管新生阻害用飲食組成物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000217543A (ja) * 1999-01-29 2000-08-08 Nakajima Mitsuhiro ハナビラタケ抽出物
JP2004043441A (ja) * 2002-05-15 2004-02-12 Bhn Kk 血管新生阻害剤およびその利用
JP2004307453A (ja) * 2003-04-07 2004-11-04 Bhn Kk 血管新生阻害剤及びその利用

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000217543A (ja) * 1999-01-29 2000-08-08 Nakajima Mitsuhiro ハナビラタケ抽出物
JP2004043441A (ja) * 2002-05-15 2004-02-12 Bhn Kk 血管新生阻害剤およびその利用
JP2004307453A (ja) * 2003-04-07 2004-11-04 Bhn Kk 血管新生阻害剤及びその利用

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
NAOHITO OHNE ET AL.: "Antitumor 1, 3-beta-Glucan from Cultured Fruit Body of Sparassis crispa", BIOL. PHARM. BULL., vol. 23, no. 7, 2000, pages 866 - 872, XP003022924 *
YAMAMOTO K. ET AL.: "Sparassis crispa beta-glucan no Kekkan Shinsei Sogai Sayo", THE PHARMACEUTICAL SOCIETY OF JAPAN NENKAI YOSHISHU, vol. 127, no. 4, 5 March 2007 (2007-03-05), pages 60, XP003022925 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010059106A (ja) * 2008-09-04 2010-03-18 Unitika Ltd 糖尿病進行抑制作用を有する組成物
JP2010100576A (ja) * 2008-10-24 2010-05-06 Unitika Ltd 便秘改善剤
JP2014001188A (ja) * 2012-06-20 2014-01-09 Hiroko Ito 血管新生阻害剤及び血管新生阻害用飲食組成物

Also Published As

Publication number Publication date
JPWO2008084574A1 (ja) 2010-04-30

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