WO2008078579A1 - 分離精製方法とマイクロ流体回路 - Google Patents

分離精製方法とマイクロ流体回路 Download PDF

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Publication number
WO2008078579A1
WO2008078579A1 PCT/JP2007/074124 JP2007074124W WO2008078579A1 WO 2008078579 A1 WO2008078579 A1 WO 2008078579A1 JP 2007074124 W JP2007074124 W JP 2007074124W WO 2008078579 A1 WO2008078579 A1 WO 2008078579A1
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separation
purification method
microparticle
substance
microfluid circuit
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PCT/JP2007/074124
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French (fr)
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Daisuke Niwa
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Rohm Co., Ltd.
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Priority to EP07850628A priority Critical patent/EP2096179A4/en
Priority to US12/439,831 priority patent/US20110003285A1/en
Publication of WO2008078579A1 publication Critical patent/WO2008078579A1/ja

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    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • C—CHEMISTRY; METALLURGY
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    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
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    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • G01N21/554—Attenuated total reflection and using surface plasmons detecting the surface plasmon resonance of nanostructured metals, e.g. localised surface plasmon resonance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles
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    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
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Abstract

　微粒子凝集反応を利用して、対象となる生体分子または生体関連物質の簡便かつ高精度の分離精製方法を提供する。また、微粒子凝集体を電気化学または表面プラズモン共鳴などの非蛍光法における検出マーカーとして利用するマイクロ流体回路を提供する。該分離精製方法は、標識対象物質と特異的に反応する標識物質により修飾された微粒子と、標識対象物質を含む生体分子または生体関連物質との反応により微粒子凝集体を生成する工程と、微粒子凝集体を分離精製する工程とを備える。該マイクロ流体回路は、該分離精製方法を利用する。
PCT/JP2007/074124 2006-12-22 2007-12-14 分離精製方法とマイクロ流体回路 WO2008078579A1 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP07850628A EP2096179A4 (en) 2006-12-22 2007-12-14 SEPARATION / PURIFICATION METHOD AND MICROFLUID CIRCUIT
US12/439,831 US20110003285A1 (en) 2006-12-22 2007-12-14 Separation purification method and microfluidic circuit

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006-346208 2006-12-22
JP2006346208A JP2008154493A (ja) 2006-12-22 2006-12-22 分離精製方法とマイクロ流体回路

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WO2008078579A1 true WO2008078579A1 (ja) 2008-07-03

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US (1) US20110003285A1 (ja)
EP (1) EP2096179A4 (ja)
JP (1) JP2008154493A (ja)
TW (1) TW200902977A (ja)
WO (1) WO2008078579A1 (ja)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008157730A (ja) * 2006-12-22 2008-07-10 Rohm Co Ltd 生体分子または生体関連物質の測定方法
WO2010134592A1 (ja) * 2009-05-22 2010-11-25 コニカミノルタホールディングス株式会社 Ｓｐｆｓ－ｌｐｆｓ系による測定方法に供するプラズモン励起センサおよびアッセイ法
JP2014505233A (ja) * 2010-10-22 2014-02-27 ティー２ バイオシステムズ インコーポレイテッド 検体の検出のためのｎｍｒシステムおよび方法
US9360457B2 (en) 2010-10-22 2016-06-07 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
US9562271B2 (en) 2012-04-20 2017-02-07 T2 Biosystems, Inc. Compositions and methods for detection of Candida species
WO2022138470A1 (ja) * 2020-12-21 2022-06-30 国立研究開発法人理化学研究所 物質の検出デバイス
US11519016B2 (en) 2016-01-21 2022-12-06 T2 Biosystems, Inc. NMR methods and systems for the rapid detection of bacteria

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JP2014055773A (ja) * 2010-12-08 2014-03-27 Kureha Corp 抗ｐｓｋポリクローナル抗体並びにそれを用いたｐｓｋの免疫学的分析方法およびｐｓｋの免疫学的分析用キット
CA2847215C (en) 2011-08-30 2020-10-20 National Research Council Of Canada Centrifugally-enhanced capture method and device
US10333752B2 (en) * 2015-03-13 2019-06-25 Qualcomm Incorporated Guard-band for scaled numerology multiplexing
US11212147B2 (en) * 2015-10-23 2021-12-28 Huawei Technologies Co., Ltd. Systems and methods for configuring carriers using overlapping sets of candidate numerologies
KR20190137882A (ko) * 2017-05-01 2019-12-11 카운슬 오브 사이언티픽 앤드 인더스트리얼 리서치 원심 분리기를 사용하는 금속 나노입자 또는 나노와이어의 계면 분리 공정

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See also references of EP2096179A4

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008157730A (ja) * 2006-12-22 2008-07-10 Rohm Co Ltd 生体分子または生体関連物質の測定方法
WO2010134592A1 (ja) * 2009-05-22 2010-11-25 コニカミノルタホールディングス株式会社 Ｓｐｆｓ－ｌｐｆｓ系による測定方法に供するプラズモン励起センサおよびアッセイ法
JP5652393B2 (ja) * 2009-05-22 2015-01-14 コニカミノルタ株式会社 Ｓｐｆｓ−ｌｐｆｓ系による測定方法に供するプラズモン励起センサおよびアッセイ法
JP2014505233A (ja) * 2010-10-22 2014-02-27 ティー２ バイオシステムズ インコーポレイテッド 検体の検出のためのｎｍｒシステムおよび方法
US9360457B2 (en) 2010-10-22 2016-06-07 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
US9488648B2 (en) 2010-10-22 2016-11-08 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
US9702852B2 (en) 2010-10-22 2017-07-11 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
US9714940B2 (en) 2010-10-22 2017-07-25 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
US9562271B2 (en) 2012-04-20 2017-02-07 T2 Biosystems, Inc. Compositions and methods for detection of Candida species
US11098378B2 (en) 2012-04-20 2021-08-24 T2 Biosystems, Inc. Compositions and methods for detection of candida species
US11519016B2 (en) 2016-01-21 2022-12-06 T2 Biosystems, Inc. NMR methods and systems for the rapid detection of bacteria
WO2022138470A1 (ja) * 2020-12-21 2022-06-30 国立研究開発法人理化学研究所 物質の検出デバイス

Also Published As

Publication number Publication date
TW200902977A (en) 2009-01-16
EP2096179A4 (en) 2010-01-27
US20110003285A1 (en) 2011-01-06
JP2008154493A (ja) 2008-07-10
EP2096179A1 (en) 2009-09-02

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