WO2008056221A3 - Crystalline sulfate salt of cephalosporin antibiotic - Google Patents

Crystalline sulfate salt of cephalosporin antibiotic Download PDF

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Publication number
WO2008056221A3
WO2008056221A3 PCT/IB2007/003341 IB2007003341W WO2008056221A3 WO 2008056221 A3 WO2008056221 A3 WO 2008056221A3 IB 2007003341 W IB2007003341 W IB 2007003341W WO 2008056221 A3 WO2008056221 A3 WO 2008056221A3
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WO
WIPO (PCT)
Prior art keywords
sulfate salt
cephalosporin antibiotic
crystalline sulfate
cephalosporin
crystalline
Prior art date
Application number
PCT/IB2007/003341
Other languages
French (fr)
Other versions
WO2008056221A2 (en
Inventor
Rajendra Janardan Sarangdhar
Balasubramanian Jothimani
Abdul Mohammed Jaffar
Sekar Selvakumar
Pramod Narayan Deshpande
Original Assignee
Orchid Chemicals & Pharm Ltd
Rajendra Janardan Sarangdhar
Balasubramanian Jothimani
Abdul Mohammed Jaffar
Sekar Selvakumar
Pramod Narayan Deshpande
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orchid Chemicals & Pharm Ltd, Rajendra Janardan Sarangdhar, Balasubramanian Jothimani, Abdul Mohammed Jaffar, Sekar Selvakumar, Pramod Narayan Deshpande filed Critical Orchid Chemicals & Pharm Ltd
Publication of WO2008056221A2 publication Critical patent/WO2008056221A2/en
Publication of WO2008056221A3 publication Critical patent/WO2008056221A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

The present invention relates to novel crystalline form of cephalosporin sulfate of the following formula and provides a process for preparing the same.
PCT/IB2007/003341 2006-11-06 2007-11-05 Crystalline sulfate salt of cephalosporin antibiotic WO2008056221A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2043CH2006 2006-11-06
IN2043/CHE/2006 2006-11-06

Publications (2)

Publication Number Publication Date
WO2008056221A2 WO2008056221A2 (en) 2008-05-15
WO2008056221A3 true WO2008056221A3 (en) 2008-07-17

Family

ID=39364883

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/003341 WO2008056221A2 (en) 2006-11-06 2007-11-05 Crystalline sulfate salt of cephalosporin antibiotic

Country Status (1)

Country Link
WO (1) WO2008056221A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101880291B (en) * 2010-07-07 2012-05-30 福建省福抗药业股份有限公司 Preparation method of cefpirome sulfate sterile powder

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112550A2 (en) * 1982-12-28 1984-07-04 Hoechst Aktiengesellschaft Crystalline acid addition salts of cephalosporins and process for their preparation
DE3626375A1 (en) * 1985-08-05 1987-02-12 Bristol Myers Co CEPHALOSPORINE SALTS AND INJECTABLE AGENTS CONTAINING THEM
KR100293728B1 (en) * 1998-05-22 2001-09-17 손 경 식 Process for producing crystalline cefpirom sulfate

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112550A2 (en) * 1982-12-28 1984-07-04 Hoechst Aktiengesellschaft Crystalline acid addition salts of cephalosporins and process for their preparation
DE3626375A1 (en) * 1985-08-05 1987-02-12 Bristol Myers Co CEPHALOSPORINE SALTS AND INJECTABLE AGENTS CONTAINING THEM
KR100293728B1 (en) * 1998-05-22 2001-09-17 손 경 식 Process for producing crystalline cefpirom sulfate

Also Published As

Publication number Publication date
WO2008056221A2 (en) 2008-05-15

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