WO2007099552A3 - Novel crystalline form of atovastatin hemi-magnesium - Google Patents

Novel crystalline form of atovastatin hemi-magnesium Download PDF

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Publication number
WO2007099552A3
WO2007099552A3 PCT/IN2007/000063 IN2007000063W WO2007099552A3 WO 2007099552 A3 WO2007099552 A3 WO 2007099552A3 IN 2007000063 W IN2007000063 W IN 2007000063W WO 2007099552 A3 WO2007099552 A3 WO 2007099552A3
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WO
WIPO (PCT)
Prior art keywords
magnesium
crystalline form
hemi
atovastatin
novel crystalline
Prior art date
Application number
PCT/IN2007/000063
Other languages
French (fr)
Other versions
WO2007099552A2 (en
Inventor
Gogulapati Venkata Panakal Rao
Chavakula Ramdas
Bandari Mohan
Gorantla Seeta Ramanjaneyulu
Original Assignee
Matrix Labaratories Ltd
Gogulapati Venkata Panakal Rao
Chavakula Ramdas
Bandari Mohan
Gorantla Seeta Ramanjaneyulu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matrix Labaratories Ltd, Gogulapati Venkata Panakal Rao, Chavakula Ramdas, Bandari Mohan, Gorantla Seeta Ramanjaneyulu filed Critical Matrix Labaratories Ltd
Publication of WO2007099552A2 publication Critical patent/WO2007099552A2/en
Publication of WO2007099552A3 publication Critical patent/WO2007099552A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to a novel crystalline form of Atorvastatin hemi-magnesium and it further relates to a process for preparation of the same through the formation of Atorvastatin hemi-magnesium isopropanol solvate.
PCT/IN2007/000063 2006-03-02 2007-02-20 Novel crystalline form of atovastatin hemi-magnesium WO2007099552A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN377/CHE/2006 2006-03-02
IN377CH2006 2006-03-02

Publications (2)

Publication Number Publication Date
WO2007099552A2 WO2007099552A2 (en) 2007-09-07
WO2007099552A3 true WO2007099552A3 (en) 2007-10-25

Family

ID=38459440

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2007/000063 WO2007099552A2 (en) 2006-03-02 2007-02-20 Novel crystalline form of atovastatin hemi-magnesium

Country Status (1)

Country Link
WO (1) WO2007099552A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1879862E (en) * 2005-05-03 2011-04-19 Ranbaxy Lab Ltd Magnesium salts of hmg-coa reductase inhibitors
WO2009063476A1 (en) * 2007-11-16 2009-05-22 Biocon Limited A crystalline form of atorvastatin hemi magnesium salt and a process thereof
KR100850850B1 (en) 2008-01-25 2008-08-06 주식회사종근당 Method for the preparation of atorvastatin and intermediates used therein
EP2130819A3 (en) 2008-04-10 2009-12-23 Ranbaxy Laboratories Limited Crystalline forms of atorvastatin magnesium
WO2009157005A1 (en) * 2008-06-26 2009-12-30 Biocon Limited Crystalline forms of atorvastatin hemi-magnesium salt and a process thereof
KR20120011249A (en) 2010-07-28 2012-02-07 주식회사 경보제약 Novel Crystal Form of Atorvastatin Hemi-Calcium, Hydrate thereof, and Method of Producing the Same
CN111362856B (en) * 2020-04-29 2023-08-18 福建海西新药创制股份有限公司 Method for producing atorvastatin calcium by utilizing micro-reaction device

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1336405A1 (en) * 2002-02-14 2003-08-20 Ranbaxy Laboratories, Ltd. Formulations of atorvastatin stabilized with alkali metal additions
EP1577297A1 (en) * 2004-03-17 2005-09-21 Ranbaxy Laboratories, Ltd. Process for the production of atorvastatin calcium in amorphous form
WO2006117761A2 (en) * 2005-05-03 2006-11-09 Ranbaxy Laboratories Limited Magnesium salts of hmg-coa reductase inhibitors

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1336405A1 (en) * 2002-02-14 2003-08-20 Ranbaxy Laboratories, Ltd. Formulations of atorvastatin stabilized with alkali metal additions
EP1577297A1 (en) * 2004-03-17 2005-09-21 Ranbaxy Laboratories, Ltd. Process for the production of atorvastatin calcium in amorphous form
WO2006117761A2 (en) * 2005-05-03 2006-11-09 Ranbaxy Laboratories Limited Magnesium salts of hmg-coa reductase inhibitors

Also Published As

Publication number Publication date
WO2007099552A2 (en) 2007-09-07

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