WO2008053358A3 - A common gene expression signature in dilated cardiomyopathy - Google Patents
A common gene expression signature in dilated cardiomyopathy Download PDFInfo
- Publication number
- WO2008053358A3 WO2008053358A3 PCT/IB2007/004191 IB2007004191W WO2008053358A3 WO 2008053358 A3 WO2008053358 A3 WO 2008053358A3 IB 2007004191 W IB2007004191 W IB 2007004191W WO 2008053358 A3 WO2008053358 A3 WO 2008053358A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- gene expression
- dilated cardiomyopathy
- expression signature
- common gene
- cardiomyopathy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
The present invention provides a convenient and highly effective microarray tool and method for diagnosing a cardiomyopathy state, especially dilated cardiomyopathy, in a subject, with a high degree of accuracy.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07866600A EP2046997A2 (en) | 2006-07-25 | 2007-07-24 | A common gene expression signature in dilated cardiomyopathy |
JP2009521384A JP2009544306A (en) | 2006-07-25 | 2007-07-24 | Common gene expression signature for dilated cardiomyopathy |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83295906P | 2006-07-25 | 2006-07-25 | |
US60/832,959 | 2006-07-25 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2008053358A2 WO2008053358A2 (en) | 2008-05-08 |
WO2008053358A3 true WO2008053358A3 (en) | 2008-11-20 |
WO2008053358A8 WO2008053358A8 (en) | 2009-08-27 |
Family
ID=39344668
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2007/004191 WO2008053358A2 (en) | 2006-07-25 | 2007-07-24 | A common gene expression signature in dilated cardiomyopathy |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2046997A2 (en) |
JP (1) | JP2009544306A (en) |
WO (1) | WO2008053358A2 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102027374A (en) * | 2008-04-30 | 2011-04-20 | 霍夫曼-拉罗奇有限公司 | Use of SFRP-3 in the assessment of heart failure |
CN110506057B (en) | 2017-02-17 | 2023-09-29 | 百时美施贵宝公司 | ALPHA synuclein antibody and application thereof |
CN110809718A (en) * | 2017-06-21 | 2020-02-18 | 韩国生命工学研究院 | Method and kit for diagnosing muscle weakness-related diseases using blood biomarkers |
CN113355332B (en) * | 2021-07-22 | 2022-09-06 | 青岛市妇女儿童医院 | HEG1 gene mutant and application thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999024571A2 (en) * | 1997-11-10 | 1999-05-20 | Curagen Corporation | Differentially expressed genes in cardiac hypertrophy and their uses in treatment and diagnosis |
WO2003006687A2 (en) * | 2001-07-10 | 2003-01-23 | Medigene Ag | Novel target genes for diseases of the heart |
WO2003040407A2 (en) * | 2001-11-09 | 2003-05-15 | Max-Planck-Gesellschaft | Novel markers for cardiopathies |
WO2005060656A2 (en) * | 2003-12-16 | 2005-07-07 | Hare Joshua M | Identification of a gene expression profile that differentiates ischemic and nonischemic cardiomyopathy |
-
2007
- 2007-07-24 WO PCT/IB2007/004191 patent/WO2008053358A2/en active Application Filing
- 2007-07-24 EP EP07866600A patent/EP2046997A2/en not_active Withdrawn
- 2007-07-24 JP JP2009521384A patent/JP2009544306A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999024571A2 (en) * | 1997-11-10 | 1999-05-20 | Curagen Corporation | Differentially expressed genes in cardiac hypertrophy and their uses in treatment and diagnosis |
WO2003006687A2 (en) * | 2001-07-10 | 2003-01-23 | Medigene Ag | Novel target genes for diseases of the heart |
WO2003040407A2 (en) * | 2001-11-09 | 2003-05-15 | Max-Planck-Gesellschaft | Novel markers for cardiopathies |
WO2005060656A2 (en) * | 2003-12-16 | 2005-07-07 | Hare Joshua M | Identification of a gene expression profile that differentiates ischemic and nonischemic cardiomyopathy |
US20050158756A1 (en) * | 2003-12-16 | 2005-07-21 | Joshua Hare | Identification of a gene expression profile that differentiates ischemic and nonischemic cardiomyopathy |
Non-Patent Citations (5)
Title |
---|
"Affimetrix GeneChip Human Genome U133 Array Set HG-U133A", GEO,, 1 January 1900 (1900-01-01), XP002254749 * |
BOHELER ET AL: "Gene expression in cardiac hypertrophy", DS IN CARDIOVASCULAR MEDICINE, ELSEVIER SCIENCE, NEW YORK, NY, US, vol. 2, no. 5, 1 September 1992 (1992-09-01), pages 176 - 182, XP002096139, ISSN: 1050-1738 * |
HWANG JUEY-JEN ET AL: "Microarray gene expression profiles in dilated and hypertrophic cardiomyopathic end-stage heart failure", PHYSIOLOGICAL GENOMICS, vol. 10, October 2002 (2002-10-01), pages 31 - 44, XP002488465, ISSN: 1094-8341 * |
TAN F-L ET AL: "The gene expression fingerprint of human heart failure", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, vol. 99, no. 17, 20 August 2002 (2002-08-20), pages 11387 - 11392, XP002970100, ISSN: 0027-8424 * |
YUNG C K ET AL: "Gene expression profiles in end-stage human idiopathic dilated cardiomyopathy: altered expression of apoptotic and cytoskeletal genes", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 83, no. 2, 1 February 2004 (2004-02-01), pages 281 - 297, XP004482956, ISSN: 0888-7543 * |
Also Published As
Publication number | Publication date |
---|---|
WO2008053358A2 (en) | 2008-05-08 |
JP2009544306A (en) | 2009-12-17 |
EP2046997A2 (en) | 2009-04-15 |
WO2008053358A8 (en) | 2009-08-27 |
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