WO2008048970A8 - Synthetic antibodies - Google Patents

Synthetic antibodies Download PDF

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Publication number
WO2008048970A8
WO2008048970A8 PCT/US2007/081536 US2007081536W WO2008048970A8 WO 2008048970 A8 WO2008048970 A8 WO 2008048970A8 US 2007081536 W US2007081536 W US 2007081536W WO 2008048970 A8 WO2008048970 A8 WO 2008048970A8
Authority
WO
Grant status
Application
Patent type
Prior art keywords
synthetic antibodies
methods
antibodies
reagents
present invention
Prior art date
Application number
PCT/US2007/081536
Other languages
French (fr)
Other versions
WO2008048970A2 (en )
WO2008048970A3 (en )
Inventor
Stephen Albert Johnston
Neal Woodbury
John C Chaput
Chris W Diehnelt
Hao Yan
Original Assignee
Univ Arizona
Stephen Albert Johnston
Neal Woodbury
John C Chaput
Chris W Diehnelt
Hao Yan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/14Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from fungi, algea or lichens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2881Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD71
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL CHEMISTRY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/10Libraries containing peptides or polypeptides, or derivatives thereof

Abstract

The present invention provides methods for synthetic antibodies, methods for making synthetic antibodies, methods for identifying ligands, and related methods and reagents.
PCT/US2007/081536 2006-10-16 2007-10-16 Synthetic antibodies WO2008048970A8 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US85204006 true 2006-10-16 2006-10-16
US60/852,040 2006-10-16
US97544207 true 2007-09-26 2007-09-26
US60/975,442 2007-09-26

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2009533482A JP2010507099A (en) 2006-10-16 2007-10-16 Synthetic antibodies
CA 2666507 CA2666507A1 (en) 2006-10-16 2007-10-16 Synthetic antibodies
EP20070844320 EP2076614A4 (en) 2006-10-16 2007-10-16 Synthetic antibodies
US12445923 US20110143953A1 (en) 2006-10-16 2007-10-16 Synthetic Antibodies
US14198316 US9863938B2 (en) 2006-10-16 2014-03-05 Synthetic antibodies

Related Child Applications (4)

Application Number Title Priority Date Filing Date
US12445923 A-371-Of-International US20110143953A1 (en) 2006-10-16 2007-10-16 Synthetic Antibodies
US44592310 A-371-Of-International 2010-11-23 2010-11-23
US14198316 Division US9863938B2 (en) 2006-10-16 2014-03-05 Synthetic antibodies
US14198316 Continuation US9863938B2 (en) 2006-10-16 2014-03-05 Synthetic antibodies

Publications (3)

Publication Number Publication Date
WO2008048970A2 true WO2008048970A2 (en) 2008-04-24
WO2008048970A3 true WO2008048970A3 (en) 2008-08-21
WO2008048970A8 true true WO2008048970A8 (en) 2009-05-28

Family

ID=39314793

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/081536 WO2008048970A8 (en) 2006-10-16 2007-10-16 Synthetic antibodies

Country Status (5)

Country Link
US (2) US20110143953A1 (en)
EP (1) EP2076614A4 (en)
JP (1) JP2010507099A (en)
CA (1) CA2666507A1 (en)
WO (1) WO2008048970A8 (en)

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EP2799448A1 (en) * 2008-05-22 2014-11-05 Bristol-Myers Squibb Company Multivalent fibronectin based scaffold domain proteins
US8343501B2 (en) 2008-11-24 2013-01-01 Bristol-Myers Squibb Company Bispecific EGFR/IGFIR binding molecules
WO2010111299A3 (en) * 2009-03-24 2011-03-31 The Arizona Board Of Regents A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University Synthetic antibodies
JP5828837B2 (en) 2009-06-02 2015-12-09 ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム Identification of small molecules that are recognized by antibodies in a subject with a neurodegenerative disease
EP2443459A4 (en) 2009-06-19 2013-09-18 Univ Arizona Compound arrays for sample profiling
US9752191B2 (en) 2009-07-09 2017-09-05 The Scripps Research Institute Gene expression profiles associated with chronic allograft nephropathy
WO2011029008A3 (en) * 2009-09-04 2011-08-18 Arizona Board Of Regents Acting For And On Behalf Of Arizona State University Synbodies to akt1
US8969289B2 (en) 2010-05-03 2015-03-03 Bristol-Myers Squibb Company Serum albumin binding molecules
ES2573108T3 (en) 2010-05-26 2016-06-06 Bristol-Myers Squibb Company Based scaffold proteins fibronectin having improved stability
CN103384681B (en) * 2010-12-23 2018-05-18 霍夫曼-拉罗奇有限公司 Binding agent
KR20140063577A (en) 2011-06-30 2014-05-27 피라말 이미징 에스에이 Direct synthesis of 18f-fluoromethoxy compounds for pet imaging and the provision of new precursors for direct radiosynthesis of protected derivatives of o-([18f]fluoromethyl) tyrosine
EP2540710A1 (en) 2011-06-30 2013-01-02 Bayer Schering Pharma Aktiengesellschaft New precursors for direct radiosynthesis of protected derivatives of O-([18F]Fluoromethyl) tyrosine
US9309298B2 (en) 2011-11-02 2016-04-12 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University Anti-bacterial polypeptides and pathogen specific synthetic antibodies
WO2013119845A1 (en) * 2012-02-07 2013-08-15 Vibrant Holdings, Llc Substrates, peptide arrays, and methods
EP2901159A2 (en) 2012-09-28 2015-08-05 Vibrant Holdings, LLC Methods, systems, and arrays for biomolecular analysis
US20150241420A1 (en) * 2012-09-05 2015-08-27 Arizona Board of Regents, Body Corp. of the State of Arizona, acting for and on behalf of Arizona S Methods for discovering therapeutic targets
CN107817348A (en) * 2012-09-05 2018-03-20 亚利桑那州评议委员会,亚利桑那州法人团体,代理和代表亚利桑那州立大学 Methods for discovering therapeutic targets
WO2014083474A1 (en) * 2012-11-30 2014-06-05 Koninklijke Philips N.V. Capture particle for selectively binding a target molecule
US10006919B2 (en) 2013-03-15 2018-06-26 Arizona Board Of Regents On Behalf Of Arizona State University Peptide array quality control
US9970932B2 (en) 2013-03-15 2018-05-15 Arizona Board Of Regents On Behalf Of Arizona State University Non-covalent patterned chemical features and use thereof in MALDI-based quality control
US10011649B2 (en) 2013-08-26 2018-07-03 Arizona Board Of Regents On Behalf Of Arizona State University High affinity synbodies for influenza
US9757472B2 (en) * 2014-07-28 2017-09-12 Arizona Board Of Regents On Behalf Of Arizona State University Proteas stabilized antibacterial peptides for S. aureus

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US6072044A (en) * 1996-04-26 2000-06-06 New York University Nanoconstructions of geometrical objects and lattices from antiparallel nucleic acid double crossover molecules
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Also Published As

Publication number Publication date Type
EP2076614A2 (en) 2009-07-08 application
WO2008048970A2 (en) 2008-04-24 application
EP2076614A4 (en) 2012-07-04 application
US20140221253A1 (en) 2014-08-07 application
CA2666507A1 (en) 2008-04-24 application
JP2010507099A (en) 2010-03-04 application
US9863938B2 (en) 2018-01-09 grant
WO2008048970A3 (en) 2008-08-21 application
US20110143953A1 (en) 2011-06-16 application

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