WO2007144080A3 - Antidepressiva-kombinations-wafer - Google Patents

Antidepressiva-kombinations-wafer Download PDF

Info

Publication number
WO2007144080A3
WO2007144080A3 PCT/EP2007/004936 EP2007004936W WO2007144080A3 WO 2007144080 A3 WO2007144080 A3 WO 2007144080A3 EP 2007004936 W EP2007004936 W EP 2007004936W WO 2007144080 A3 WO2007144080 A3 WO 2007144080A3
Authority
WO
WIPO (PCT)
Prior art keywords
combination
active ingredient
depression
antidepressants
wafer
Prior art date
Application number
PCT/EP2007/004936
Other languages
English (en)
French (fr)
Other versions
WO2007144080A2 (de
Inventor
Hans-Rainer Hoffmann
Reto Braendli
Frank Theobald
Original Assignee
Lohmann Therapie Syst Lts
Hans-Rainer Hoffmann
Reto Braendli
Frank Theobald
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts, Hans-Rainer Hoffmann, Reto Braendli, Frank Theobald filed Critical Lohmann Therapie Syst Lts
Priority to EP07725804A priority Critical patent/EP2029097A2/de
Priority to JP2009514661A priority patent/JP2009539892A/ja
Priority to CA002652476A priority patent/CA2652476A1/en
Priority to US12/308,194 priority patent/US20090203670A1/en
Publication of WO2007144080A2 publication Critical patent/WO2007144080A2/de
Publication of WO2007144080A3 publication Critical patent/WO2007144080A3/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Die vorliegende Erfindung betrifft Flächenförmige, bei Kontakt mit Feuchtigkeit schnell zerfallende, Arzneimittelzubereitung auf Basis hydrophiler Polymere zur Freisetzung mindestens eines Wirkstoffs, wobei die Darreichungsform eine Wirkstoffkombination zur Depressionstherapie enthält und mindestens einer der Wirkstoffe aus der Gruppe der Antidepressiva ausgewählt ist. Die Erfindung betrifft ferner die Verwendung einer solchen Wirkstoffkombination zur Herstellung eines oral verabreichbaren Arzneimittels zur Behandlung von Depressionen, sowie die therapeutische Behandlung von Depressionen durch orale Verabreichung einer der genannten Arzneimittelzubereitungen.
PCT/EP2007/004936 2006-06-16 2007-06-04 Antidepressiva-kombinations-wafer WO2007144080A2 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP07725804A EP2029097A2 (de) 2006-06-16 2007-06-04 Antidepressiva-kombinations-wafer
JP2009514661A JP2009539892A (ja) 2006-06-16 2007-06-04 組み合わせ抗うつ薬ウェーハ
CA002652476A CA2652476A1 (en) 2006-06-16 2007-06-04 Combination antidepressants wafer
US12/308,194 US20090203670A1 (en) 2006-06-16 2007-06-04 Combination Antidepressants Wafer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102006027792.9 2006-06-16
DE102006027792A DE102006027792A1 (de) 2006-06-16 2006-06-16 Antidepressiva-Kombinations-Wafer

Publications (2)

Publication Number Publication Date
WO2007144080A2 WO2007144080A2 (de) 2007-12-21
WO2007144080A3 true WO2007144080A3 (de) 2008-04-24

Family

ID=38667454

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2007/004936 WO2007144080A2 (de) 2006-06-16 2007-06-04 Antidepressiva-kombinations-wafer

Country Status (7)

Country Link
US (1) US20090203670A1 (de)
EP (1) EP2029097A2 (de)
JP (1) JP2009539892A (de)
CN (1) CN101460145A (de)
CA (1) CA2652476A1 (de)
DE (1) DE102006027792A1 (de)
WO (1) WO2007144080A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009214307A1 (en) * 2008-02-13 2009-08-20 Bayer Intellectual Property Gmbh Drug delivery system with stabilising effect
JP2011511823A (ja) * 2008-02-13 2011-04-14 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト エストラジオール含有薬物の送達システム
CN101966151B (zh) * 2010-09-06 2011-11-09 海南美大制药有限公司 马来酸曲米帕明脂质体固体制剂
US9687445B2 (en) 2012-04-12 2017-06-27 Lts Lohmann Therapie-Systeme Ag Oral film containing opiate enteric-release beads
WO2016138357A1 (en) 2015-02-27 2016-09-01 Kindred Biosciences, Inc. Stimulation of appetite, management of weight loss, and treatment of anorexia in dogs and cats
CN106729652A (zh) * 2016-11-30 2017-05-31 郑州仁宏医药科技有限公司 一种治疗抑郁症的西药组合物及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001043728A1 (de) * 1999-12-14 2001-06-21 Lts Lohmann Therapie-Systeme Ag Flache arzneizubereitung zur transmucosalen verabreichung von oxycodon oder einem vergleichbaren wirkstoff in der mundhöhle, für die anwendung in der schmerztherapie und suchttherapie
WO2003070227A1 (de) * 2002-02-21 2003-08-28 Lts Lohmann Therapie-Systeme Ag Geschmacksmaskierte film- oder oblatenförmige arzneizubereitung
WO2004105767A1 (en) * 2003-06-02 2004-12-09 Sigma Pharma Ltda. Pharmaceutical composition based on agonist of benzodiazepine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10018834A1 (de) * 2000-04-15 2001-10-25 Lohmann Therapie Syst Lts Transdermale oder transmucosale Darreichungsformen mit einer nicotinhaltigen Wirkstoffkombination zur Raucherentwöhnung
DE10328942A1 (de) * 2003-06-27 2005-01-27 Lts Lohmann Therapie-Systeme Ag Transmukosale Darreichungsformen mit verminderter Schleimhautirritation
DE10354894A1 (de) * 2003-11-24 2005-07-07 Hf Arzneimittelforschung Gmbh Orale Formulierungen des Desoxypeganins und deren Anwendungen

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001043728A1 (de) * 1999-12-14 2001-06-21 Lts Lohmann Therapie-Systeme Ag Flache arzneizubereitung zur transmucosalen verabreichung von oxycodon oder einem vergleichbaren wirkstoff in der mundhöhle, für die anwendung in der schmerztherapie und suchttherapie
WO2003070227A1 (de) * 2002-02-21 2003-08-28 Lts Lohmann Therapie-Systeme Ag Geschmacksmaskierte film- oder oblatenförmige arzneizubereitung
WO2004105767A1 (en) * 2003-06-02 2004-12-09 Sigma Pharma Ltda. Pharmaceutical composition based on agonist of benzodiazepine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BAILER U ET AL: "MIRTAZAPIN BEI STATIONAER BEHANDELTEN DEPRESSIVEN PATIENTEN", WIENER KLINISCHE WOCHENSCHRIFT, NEW YORK, NY, US, vol. 18, no. 18, October 1998 (1998-10-01), pages 621 - 624, XP000922646, ISSN: 0043-5325 *

Also Published As

Publication number Publication date
WO2007144080A2 (de) 2007-12-21
DE102006027792A1 (de) 2007-12-20
CA2652476A1 (en) 2007-12-21
US20090203670A1 (en) 2009-08-13
JP2009539892A (ja) 2009-11-19
CN101460145A (zh) 2009-06-17
EP2029097A2 (de) 2009-03-04

Similar Documents

Publication Publication Date Title
WO2008028193A3 (en) Colon-targeted oral formulations of cytidine analogs
WO2005097076A3 (en) Low dose pharmaceutical products
TNSN08079A1 (en) Pharmaceutical compositions for the treatment of inner ear disorders
HK1111609A1 (en) Solid dosage form comprising proton pump inhibitor and suspension made thereof
WO2008128740A8 (en) Titration of tapentadol
WO2013158814A8 (en) Immediate release, abuse deterrent pharmaceutical compositions
MX2012007410A (es) Compuestos antivirales novedosos.
DE60121301D1 (de) Flibanserin zur Behandlung extrapyramidaler Bewegungsstörungen
WO2007144080A3 (de) Antidepressiva-kombinations-wafer
WO2007002597A3 (en) Modified-release formulations of a bupropion salt
WO2006089082A3 (en) Transmucosal administration of drug compositions for treating and preventing disorders in animals
SG166115A1 (en) Pharmaceutical preparation containing meloxicam
WO2008021113A3 (en) Transdermal methods and systems for treating alzheimer's disease
NZ605469A (en) Nalbuphine-based formulations and uses thereof
ECSP045029A (es) Composiciones de valdecoxib de disgregación intraoral
NO20071354L (no) anvendelse av samme Butylftalid selvemulsifiserene medikamentavgivelsessystem, samt fremgangsmater for fremstilling og anvendelse av samme.
TW200602090A (en) Antibiotic-based pharmaceutical formulation in microcapsular form
MX344787B (es) Composiciones que contienen berberina o analogos de la misma para tratar rosacea o trastornos de la piel relacionados con enrojecimiento de la cara.
WO2008116890A3 (en) Pharmaceutical compositions comprising flibanserin and a further agent in the treatment of sexual disorders
BRPI0513598A (pt) formas de dosagem em comprimidos revestidos de liberação entérica
WO2010090494A3 (ko) 5-벤질아미노살리실산 유도체 또는 이의 염의 의약 용도
WO2011151722A3 (en) Methods and compositions for oral pharmaceutical therapy
WO2006008173A3 (en) Pharmaceutical formulations for inhalation
WO2008148573A3 (de) Arzeimittel mit einer wirkstoffkombination enthaltend pantothensäure oder deren derivate zur behandlung von allergischen symptomen
WO2006115770A3 (en) Orally disintegrating pharmaceutical tablet formulations of olanzapine

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200780020694.3

Country of ref document: CN

DPE2 Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07725804

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2652476

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2007725804

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 12308194

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: 2009514661

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: RU

ENP Entry into the national phase

Ref document number: PI0711248

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20081128