WO2007129487A1 - Alimentation de bétail - Google Patents

Alimentation de bétail Download PDF

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Publication number
WO2007129487A1
WO2007129487A1 PCT/JP2007/052245 JP2007052245W WO2007129487A1 WO 2007129487 A1 WO2007129487 A1 WO 2007129487A1 JP 2007052245 W JP2007052245 W JP 2007052245W WO 2007129487 A1 WO2007129487 A1 WO 2007129487A1
Authority
WO
WIPO (PCT)
Prior art keywords
feed
milk
trehalose
calcium
milk yield
Prior art date
Application number
PCT/JP2007/052245
Other languages
English (en)
Japanese (ja)
Inventor
Shinji Ito
Motoshi Suzuki
Original Assignee
Idemitsu Kosan Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idemitsu Kosan Co., Ltd. filed Critical Idemitsu Kosan Co., Ltd.
Publication of WO2007129487A1 publication Critical patent/WO2007129487A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/163—Sugars; Polysaccharides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs

Definitions

  • the present invention relates to a milk yield increasing agent for mammals and a feed containing the same.
  • the present invention also relates to a calcium absorption promoter for livestock belonging to mammals, a calcium extender in milk, and a feed containing the same.
  • Methods for increasing milk yield include adding maltose, sucrose, starch, etc. to the feed to increase the amount of energy intake, controlling the type of amino acid to be administered and the timing of administration (Patent Documents 1 to 3) is known.
  • Patent Documents 1 to 3 there is a problem that the method of administering saccharides and starch cannot obtain a sufficient effect, resulting in poor feed efficiency, and the method of administering amino acid is very complicated to adjust the addition timing. There was a problem.
  • Trehalose is a non-reducing disaccharide having glucose as a structural unit, and is widely distributed in mold, yeast, red algae, lichens, and many insects. Trehalose is known to have an anti-aging effect on starch, an anti-denaturation effect on proteins, and an anti-fouling effect on lipids, and is widely used for the purpose of improving the storage stability of foods.
  • Patent Documents 4 and 5 a technique for improving the storage stability of animal feed using the above-mentioned effects of trehalose has been reported.
  • trehalose is used for the purpose of improving the stability of contained components, such as increasing the residual rate of feed enzymes by utilizing the protein denaturation preventing effect.
  • trehalose is used as a sweetener to impart palatability (Patent Document 6).
  • the administration of trehalose to mammals to increase milk yield should be studied.
  • vitamin D As a method for increasing the absorption rate of calcium, a method of administering vitamin D is known. However, since vitamin D has side effects such as promoting the deposition of blood vessel walls and calcium when taken too much, it must be used under strict control.
  • Non-patent Document 1 trehalose is known to interact with calcium and suppress the formation of insoluble salts such as calcium phosphate.
  • insoluble salts such as calcium phosphate
  • mice it is also known that when trehalose is orally administered simultaneously with calcium chloride, the calcium concentration in blood increases! / Non-patent document 2).
  • Patent Document 1 Japanese Patent Application Laid-Open No. 5-92093
  • Patent Document 2 JP-A-6-237701
  • Patent Document 3 Japanese Patent Laid-Open No. 2001-86940
  • Patent Document 4 Japanese Translation of Special Publication 2002-536005
  • Patent Document 5 JP-A-6-217716
  • Patent Document 6 Japanese Unexamined Patent Application Publication No. 2004-210795
  • Non-Patent Document 1 Ikuo Sawaya, “Interaction between trehalose and minerals”, 5th Treha Symposium, p. 41 -48, 2001
  • Non-Patent Document 2 Naruyuki Arai et al., “Trehalose and Osteoporosis”, The 3rd Treha Symposium Collection, p.
  • An object of the present invention is to provide a safe and simple means for increasing the milk yield of a mammal. It is another object of the present invention to provide a safe and simple means for stably maintaining the calcium concentration of milk even when the amount of milk is increased.
  • the present invention is as follows.
  • a mammalian milk yield increasing agent containing trehalose as an active ingredient containing trehalose as an active ingredient.
  • a method for raising a mammal comprising supplying the feed according to (3) or (4) to a lactating mammal.
  • a calcium absorption promoter for livestock belonging to mammals containing trehalose as an active ingredient (6) A calcium absorption promoter for livestock belonging to mammals containing trehalose as an active ingredient.
  • a calcium extender in the milk of livestock belonging to mammals containing trehalose as an active ingredient is a calcium extender in the milk of livestock belonging to mammals containing trehalose as an active ingredient.
  • a method for raising livestock belonging to mammals comprising supplying the feed according to (9) or (10) to livestock belonging to lactating mammals.
  • FIG. 1 is a graph showing changes in milk yield of dairy cows.
  • FIG. 2 is a graph showing the total amount of calcium contained in milk.
  • the milk yield increasing agent of the present invention is characterized by containing trehalose as an active ingredient.
  • the trehalose contained in the milk yield increasing agent of the present invention may be any of ⁇ , ⁇ -trehalose, a, j8-trehalose, ⁇ , ⁇ -trehalose, but preferably a, a-trenorose. is there.
  • the production method, origin and form of trehalose are not limited.
  • trehalose found in nature such as trehalose derived from yeast may be used, and trehalose produced by maltose starch may be used. It is also possible to use trehalose sold on the market.
  • the concentration of trehalose in the milk yield increasing agent of the present invention can be adjusted as appropriate depending on the type of feed to be added, etc.
  • Trehalose is 0.02 to 1. Og per kg body weight per day, preferably It is preferable that the concentration is suitable for giving 0.02 to 0.40 g or that the trehalose content of the feed is 10 to 1000 ppm by mass per dry substance.
  • the dosage form of the milk yield increasing agent of the present invention is not particularly limited, and may be any form such as powder, liquid, tablet, and the like.
  • the method for producing the milk yield-increasing agent of the present invention is not particularly limited, and for example, it can be produced by mixing trehalose and, if necessary, optional ingredients and preparing a formulation.
  • the milk yield increasing agent of the present invention may further contain optional components such as a component effective for increasing milk yield and a component for improving storage stability.
  • Optional ingredients include, for example, viable agents such as Enterococcus, Bacillus, and Bifidobacteria, enzymes such as amylase and lipase, vitamins such as L-corsorbic acid, salt ⁇ choline, inositol, and folic acid, salt ⁇ ⁇ ⁇ ⁇ Minerals such as potassium, iron citrate, magnesium oxide, phosphates, amino acids such as DL-alanine, DL-methionine, L-lysine, organic acids such as fumaric acid, butyric acid, lactic acid, acetic acid and their salts, Antioxidants such as ethoxyquin and dibutylhydroxytoluene, fungicides such as calcium propionate, binders such as carboxymethylcellulose, sodium caseinate and sodium polyacrylate, emulsifiers such as glycerin fatty acid ester and sorbitan fatty acid ester, fasta xanthine, Canthaxanthin Which dyes, est
  • the milk yield increasing agent containing trehalose of the present invention as an active ingredient is mixed with other feed ingredients used for mammal feed, pet food, and supplements for pets (hereinafter referred to as feed). It can be used as a feed for increasing the milk yield of mammals. There are no particular restrictions on the type and ingredients of the feed. Further, the feed of the present invention may be prepared by adding an optional ingredient that can be added to the milk yield increasing agent! /.
  • the trehalose content in the feed of the present invention can be adjusted as appropriate according to the type of animal to be fed, the composition of the feed, age, weight, time, etc., and is not particularly limited, but is 10 mass ppm to 10000 mass ppm per dry matter amount. Preferably there is.
  • the milk yield increasing agent of the present invention may be added to the feed ingredients as they are and mixed. Carrot supplementation can be performed by sprinkling the top of the feed.
  • a powdery or solid milk increasing agent when added and mixed, it can be used in liquid or gel form for easy mixing with feed.
  • water, vegetable oils such as soybean oil, rapeseed oil and corn oil, liquid animal oils, water-soluble polymer compounds such as polybulal alcohol, polybulurpyrrolidone and polyacrylic acid can be used as the liquid carrier.
  • water-soluble polysaccharides such as alginic acid, sodium alginate, xanthan gum, sodium caseinate, gum arabic, guar gum, tamarind seed polysaccharide to maintain the homogeneity of trehalose in the feed.
  • the animal that provides the feed of the present invention is a lactating mammal.
  • the lactation period varies depending on the animal species, but is usually about 12 months after delivery.
  • it can use for pets, such as livestock, a dog, and a cat, for example.
  • livestock particularly cattle, goats and sheep.
  • livestock particularly cattle, goats and sheep.
  • livestock particularly cattle, goats and sheep.
  • dairy cows among these, it can be particularly suitably used for raising dairy cows.
  • the amount of feed to be fed can be adjusted as appropriate according to the type of animal, body weight, age, health condition, ingredients of the feed, etc. Can be given in the range of 0.02g to 0.4g.
  • the dosage of trehalose is preferably 10 to 50 Og per head per day.
  • the time when the feed of the present invention is supplied is not particularly limited, and it is particularly effective when used after 2 months after delivery when the amount of 1S milk starts to decrease. Also keep The fee will be provided in the usual way.
  • the milk yield-increasing agent of the present invention can be added to and dissolved in water and provided to lactating mammals. Among these, it is preferable to provide it as drinking water to livestock, particularly cattle, goats and sheep. In this case, the amount of milk added to the milk yield increasing agent can be adjusted so that the dosage of trehalose falls within the above range, as in the case of feed. Moreover, the method for providing drinking water is not particularly limited, and may be, for example, free intake.
  • the calcium absorption promoter of the present invention is characterized by containing trehalose as an active ingredient.
  • the trehalose contained in the calcium absorption promoter of the present invention is the same as the above-mentioned milk yield increasing agent.
  • concentration of trehalose in the calcium absorption enhancer of the present invention, the dosage form of the calcium absorption enhancer, and the optional components contained therein can be appropriately selected in the same manner as the milk yield increasing agent described above.
  • the calcium absorption promoter of the present invention can be mixed with other feed ingredients used in livestock feed to make a feed for promoting calcium absorption.
  • feed ingredients used in livestock feed to make a feed for promoting calcium absorption.
  • the feed of the present invention may be prepared by adding the above-mentioned optional components that can be added to the milk yield increasing agent of the present invention. Also preferred is a combination with calcium supplements.
  • the trehalose content in the feed for promoting calcium absorption according to the present invention can be adjusted as appropriate as in the case of the milk yield increasing agent.
  • the animal that supplies the feed containing the calcium absorption enhancer of the present invention is a livestock belonging to a mammal. Among these, it can use suitably with respect to a cow, a goat, and a sheep.
  • the method for supplying the feed of the present invention is not particularly limited, and can be performed in the same manner as the feed containing the milk yield increasing agent.
  • the calcium extender in milk of the present invention is characterized by containing trehalose as an active ingredient.
  • the calcium extender of the present invention has the action of increasing the milk yield of livestock belonging to mammals and maintaining the calcium concentration in the milk. As a result, the total amount of calcium used for milk production is increased.
  • the concentration of trehalose in the calcium extender of the present invention, the dosage form of the calcium absorption promoter, and the optional ingredients contained therein are as described above. It can be appropriately selected in the same manner as the milk yield increasing agent and calcium absorption promoter.
  • the calcium extender in milk of the present invention is mixed with other feed ingredients used in livestock feed to increase the milk yield and serve as a feed for maintaining the calcium concentration in the milk.
  • the trehalose content, the type and ingredients of the feed are not particularly limited, and can be prepared in the same manner as the feed containing the milk yield-increasing agent and calcium absorption promoter of the present invention.
  • the form combined with a calcium supplement etc. is also preferable.
  • the feed supply method is not particularly limited, and can be performed in the same manner as the feed supply containing a milk yield increasing agent or a calcium absorption promoter.
  • milk yield tends to decrease gradually in the group bred with no trehalose-added feed, but overall milk yield is higher in the group bred with trehalose-added feed. In addition, the decrease in milk yield was also low. In particular, the increase in milk yield was significant in the group administered trehalose at a daily dose of 50 g or 200 g. On the other hand, in the group to which maltose was added, an increase in milk yield was not confirmed.
  • the milk yield of the mammal is increased and stabilized.
  • the absorption of calcium by mammals is promoted and the milk yield is increased, a certain quality can be maintained without lowering the calcium concentration in milk.
  • the total amount of calcium utilized for the production of mammalian milk is increased.
  • the feed containing the milk yield increasing agent and the feed containing the calcium absorption enhancer of the present invention are particularly suitable for feeding to cattle, goats and sheep.

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Birds (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)

Abstract

L'invention concerne un moyen simple et sans danger pour augmenter la quantité de lait produite par un mammifère. L'invention concerne également un moyen de stabiliser la concentration de calcium dans le lait lorsque la quantité de lait est augmentée. Un tréhalose est ajouté à une alimentation, et l'alimentation est utilisée pour nourrir un mammifère.
PCT/JP2007/052245 2006-05-01 2007-02-08 Alimentation de bétail WO2007129487A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2006-127400 2006-05-01
JP2006127400 2006-05-01
JP2006-193924 2006-07-14
JP2006193924A JP5346433B2 (ja) 2006-05-01 2006-07-14 家畜用飼料

Publications (1)

Publication Number Publication Date
WO2007129487A1 true WO2007129487A1 (fr) 2007-11-15

Family

ID=38667599

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/052245 WO2007129487A1 (fr) 2006-05-01 2007-02-08 Alimentation de bétail

Country Status (3)

Country Link
JP (1) JP5346433B2 (fr)
TW (1) TW200742552A (fr)
WO (1) WO2007129487A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009291151A (ja) * 2008-06-06 2009-12-17 Dainichiseika Color & Chem Mfg Co Ltd 家畜又は伴侶動物用の飼料組成物及び飲用水
JP2013223481A (ja) * 2012-07-24 2013-10-31 Meiji Shiryo Kk 家畜の乳質改善剤
JP5899098B2 (ja) * 2012-10-04 2016-04-06 明治飼糧株式会社 家畜の乳の青臭み抑制剤
JP5894615B2 (ja) * 2014-01-30 2016-03-30 明治飼糧株式会社 家畜の暑熱ストレス軽減剤
JPWO2022138631A1 (fr) * 2020-12-25 2022-06-30

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000316513A (ja) * 1999-05-13 2000-11-21 Tajimaya Shokuhin Kk 納豆油含有大豆加工食品
JP2001095499A (ja) * 1999-09-29 2001-04-10 Showa Sangyo Co Ltd 卵殻強化剤及び該剤を含有する鶏用飼料
WO2002038146A1 (fr) * 2000-11-07 2002-05-16 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Immunomodulateur mucosal et son utilisation
JP2004129622A (ja) * 2002-10-15 2004-04-30 Nippon Formula Feed Mfg Co Ltd 水産養殖用飼料

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ515869A (en) * 2001-11-30 2003-09-26 Med Chem Ingredients Ltd Compositions and methods for animal treatment comprising gluco- and isomalto- oligosaccharides

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000316513A (ja) * 1999-05-13 2000-11-21 Tajimaya Shokuhin Kk 納豆油含有大豆加工食品
JP2001095499A (ja) * 1999-09-29 2001-04-10 Showa Sangyo Co Ltd 卵殻強化剤及び該剤を含有する鶏用飼料
WO2002038146A1 (fr) * 2000-11-07 2002-05-16 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Immunomodulateur mucosal et son utilisation
JP2004129622A (ja) * 2002-10-15 2004-04-30 Nippon Formula Feed Mfg Co Ltd 水産養殖用飼料

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KATAYAMA Y.: "Mg Kyushu ni Oyobosu Trehalose no Eikyo", JOURNAL OF APPLIED GLYCOSCIENCE, vol. 51, no. SUPPL., 2004, pages 44, XP003016983 *
NISHIOKA S.: "Trehalose Sesshu ni yoru Kotsumitsudo to Kotsutaisha Marker no Henka", THE JAPANESE SOCIETY OF NUTRITION AND FOOD SCIENCE SOKAI KOEN YOSHISHU, vol. 55TH, 2001, pages 114, XP003016984 *

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Publication number Publication date
TW200742552A (en) 2007-11-16
JP5346433B2 (ja) 2013-11-20
JP2007319156A (ja) 2007-12-13

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