WO2007101357A3 - Haarwuchsmittel zur behandlung von menschlichen keratinfasern und verfahren zu dessen herstellung - Google Patents

Haarwuchsmittel zur behandlung von menschlichen keratinfasern und verfahren zu dessen herstellung Download PDF

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Publication number
WO2007101357A3
WO2007101357A3 PCT/CH2007/000089 CH2007000089W WO2007101357A3 WO 2007101357 A3 WO2007101357 A3 WO 2007101357A3 CH 2007000089 W CH2007000089 W CH 2007000089W WO 2007101357 A3 WO2007101357 A3 WO 2007101357A3
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WO
WIPO (PCT)
Prior art keywords
substance
butyl avocadate
pyrimidine oxide
treatment
production
Prior art date
Application number
PCT/CH2007/000089
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English (en)
French (fr)
Other versions
WO2007101357A2 (de
Inventor
Nazmi Krasniqi
Original Assignee
Pelloni Claudio
Nazmi Krasniqi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pelloni Claudio, Nazmi Krasniqi filed Critical Pelloni Claudio
Publication of WO2007101357A2 publication Critical patent/WO2007101357A2/de
Publication of WO2007101357A3 publication Critical patent/WO2007101357A3/de

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

Das Mittel enthält Butyl-Avocadate und ist als Haarwuchsmittel zur lokalen Behandlung von Alopecia androgenetica geeignet. Das Butyl-Avocadate wird bevorzugt mit mindestens einem Pyrimidin Oxid oder Pyrimidin Oxid Derivat, zum Beispiel ein 2,4-Diaminopyrimidin 3-Oxid Derivat, und mit mindestens einem Bioflavanoid und/oder mit Dimethylsulfoxid kombiniert. Vorteilhaft ist das Butyl-Avocadate in einer Konzentration von 5 - 50 % vorhanden. Als Pyrimidin Oxid Derivate kommen insbesondere Minoxidil, Kopexil und/oder Kopyrrol in Frage. Als Bioflavanoide beispielsweise Taxifolin, Astibilin, Myricetin, Oligomere Procyanidin, Catechin, Epicate- chin, Ferulsäure und/oder Pycnogenol. Durch dieses Mittel kommt es nach relativ kurzer Zeit zu einem signifikanten Wachstum normaler Haare, das heisst, zu einem anagenen Wachstum. Dies besonders dann, wenn es neben dem Butyl-Avocadate gleichzeitig zwei Pyrimidin Oxid Derivate und mindestens ein Bioflavanoid oder Dimethylsulfoxid enthält. Das Mittel ist gut verträglich.
PCT/CH2007/000089 2006-03-07 2007-02-21 Haarwuchsmittel zur behandlung von menschlichen keratinfasern und verfahren zu dessen herstellung WO2007101357A2 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CH360/06 2006-03-07
CH3602006 2006-03-07
CH1340/06 2006-08-22
CH13402006 2006-08-22
CH203/07 2007-02-07
CH2032007 2007-02-07

Publications (2)

Publication Number Publication Date
WO2007101357A2 WO2007101357A2 (de) 2007-09-13
WO2007101357A3 true WO2007101357A3 (de) 2008-07-03

Family

ID=37951501

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CH2007/000089 WO2007101357A2 (de) 2006-03-07 2007-02-21 Haarwuchsmittel zur behandlung von menschlichen keratinfasern und verfahren zu dessen herstellung

Country Status (1)

Country Link
WO (1) WO2007101357A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009101497A2 (en) * 2008-02-11 2009-08-20 Glenmark Pharmaceuticals Limited Topical pharmaceutical combination comprising minoxidil and aminexil
CN101508782B (zh) * 2009-03-09 2013-01-16 东华大学 一种以有机酸溶剂分离提取天然角蛋白纤维中原纤状结构体的方法
WO2018229072A1 (de) * 2017-06-16 2018-12-20 Capilli Med Gmbh Zusammensetzung zur verhinderung von haarausfall und wachstumsförderung von haaren
CN107970128B (zh) * 2017-12-06 2021-01-15 彭氏(惠州)实业发展有限公司 一种含有二氨基嘧啶氧化物的生发液配方与生产工艺
CN114901247A (zh) * 2019-12-30 2022-08-12 莱雅公司 用于护理角蛋白材料的无水组合物
CN112370445A (zh) * 2020-10-13 2021-02-19 吉林大学 紫杉叶素在抑制毛发生长的用途

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4139619A (en) * 1976-05-24 1979-02-13 The Upjohn Company 6-Amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrimidine, topical compositions and process for hair growth
WO1992001437A1 (fr) * 1990-07-20 1992-02-06 L'oreal Utilisation de derives de pyrimidine 3-oxyde pour freiner la chute des cheveux et compositions topiques mises en ×uvre
WO2001052837A2 (fr) * 2000-01-18 2001-07-26 Laboratoires Pharmascience Utilisation d'au moins un ester gras pour la preparation d'une composition destinee a inhiber l'activite de la 5 alpha reductase, en pharmacie notamment en dermatologie, en cosmetique et en tant qu'additif alimentaire
EP1604640A1 (de) * 2004-04-30 2005-12-14 KPSS-Kao Professional Salon Services GmbH Mittel zur Behandlung der Haare und der Kopfhaut

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4139619A (en) * 1976-05-24 1979-02-13 The Upjohn Company 6-Amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrimidine, topical compositions and process for hair growth
WO1992001437A1 (fr) * 1990-07-20 1992-02-06 L'oreal Utilisation de derives de pyrimidine 3-oxyde pour freiner la chute des cheveux et compositions topiques mises en ×uvre
WO2001052837A2 (fr) * 2000-01-18 2001-07-26 Laboratoires Pharmascience Utilisation d'au moins un ester gras pour la preparation d'une composition destinee a inhiber l'activite de la 5 alpha reductase, en pharmacie notamment en dermatologie, en cosmetique et en tant qu'additif alimentaire
EP1604640A1 (de) * 2004-04-30 2005-12-14 KPSS-Kao Professional Salon Services GmbH Mittel zur Behandlung der Haare und der Kopfhaut

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PICCARDI ET AL.: "P02.14: Pharmacological and clinical activities of 5-alpha Avocuta. Application for the management of androgenic disorders", JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEROLOGY, vol. 18, no. s2, November 2004 (2004-11-01), pages 223 - 223, XP002465401 *

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