WO2007057490A3 - Immunogenic polypeptides of presenilin-1-associated protein (psap), methods of obtaining antibodies and use of same - Google Patents

Immunogenic polypeptides of presenilin-1-associated protein (psap), methods of obtaining antibodies and use of same Download PDF

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Publication number
WO2007057490A3
WO2007057490A3 PCT/ES2006/000636 ES2006000636W WO2007057490A3 WO 2007057490 A3 WO2007057490 A3 WO 2007057490A3 ES 2006000636 W ES2006000636 W ES 2006000636W WO 2007057490 A3 WO2007057490 A3 WO 2007057490A3
Authority
WO
WIPO (PCT)
Prior art keywords
psap
methods
same
presenilin
associated protein
Prior art date
Application number
PCT/ES2006/000636
Other languages
Spanish (es)
French (fr)
Other versions
WO2007057490A2 (en
Inventor
Villar Jose Albert Carrodeguas
Gay Violeta Lamarca
Clemente Antonio Sanz
Original Assignee
Univ Zaragoza
Villar Jose Albert Carrodeguas
Gay Violeta Lamarca
Clemente Antonio Sanz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Zaragoza, Villar Jose Albert Carrodeguas, Gay Violeta Lamarca, Clemente Antonio Sanz filed Critical Univ Zaragoza
Publication of WO2007057490A2 publication Critical patent/WO2007057490A2/en
Publication of WO2007057490A3 publication Critical patent/WO2007057490A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors

Abstract

The invention relates to polynucleotides which code for immunogenic peptides that can produce antibodies which interact with membrane protein PSAP. The invention also relates to methods of obtaining the aforementioned antibodies and to uses of same.
PCT/ES2006/000636 2005-11-18 2006-11-16 Immunogenic polypeptides of presenilin-1-associated protein (psap), methods of obtaining antibodies and use of same WO2007057490A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200502840A ES2319477B1 (en) 2005-11-18 2005-11-18 PSAP ISOFORMS, ANTIGENIC DETERMINANTS, METHOD OF OBTAINING ANTIBODIES AND USES OF THE SAME.
ESP200502840 2005-11-18

Publications (2)

Publication Number Publication Date
WO2007057490A2 WO2007057490A2 (en) 2007-05-24
WO2007057490A3 true WO2007057490A3 (en) 2007-07-05

Family

ID=38049004

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ES2006/000636 WO2007057490A2 (en) 2005-11-18 2006-11-16 Immunogenic polypeptides of presenilin-1-associated protein (psap), methods of obtaining antibodies and use of same

Country Status (2)

Country Link
ES (1) ES2319477B1 (en)
WO (1) WO2007057490A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2319602B1 (en) * 2007-07-13 2010-02-16 Univ Zaragoza POLYPETIDES DERIVED FROM THE PSAP PROTEIN (PSESENILIN 1-ASSOCIATED PROTEIN) ABLE TO INDUCE APOPTOSIS AND USES THEMSELVES.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000004150A1 (en) * 1998-07-16 2000-01-27 Incyte Pharmaceuticals, Inc. Human presenilin-associated protein
WO2004078112A2 (en) * 2003-03-07 2004-09-16 Asahi Kasei Pharma Corporation Apoptosis inducing gene

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000004150A1 (en) * 1998-07-16 2000-01-27 Incyte Pharmaceuticals, Inc. Human presenilin-associated protein
WO2004078112A2 (en) * 2003-03-07 2004-09-16 Asahi Kasei Pharma Corporation Apoptosis inducing gene

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
XU X. ET AL.: "Identification of a novel PSD-95/Dlg/ZO-1 (PDZ)-like protein interacting with the C terminus of presenilin-1", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 46, 12 November 1999 (1999-11-12), pages 32543 - 32546, XP000879633 *
XU X. ET AL.: "The novel presenilin-1 associated protein is a proapoptopic mitochondrial protein", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 277, no. 50, 13 December 2002 (2002-12-13), pages 48913 - 48922, XP003015413 *

Also Published As

Publication number Publication date
WO2007057490A2 (en) 2007-05-24
ES2319477A1 (en) 2009-05-07
ES2319477B1 (en) 2010-02-16

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