WO2007028608A3 - Nukleinsäure-bindende chips zur detektion von stickstoffmangelzuständen im rahmen der bioprozesskontrolle - Google Patents

Nukleinsäure-bindende chips zur detektion von stickstoffmangelzuständen im rahmen der bioprozesskontrolle Download PDF

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Publication number
WO2007028608A3
WO2007028608A3 PCT/EP2006/008726 EP2006008726W WO2007028608A3 WO 2007028608 A3 WO2007028608 A3 WO 2007028608A3 EP 2006008726 W EP2006008726 W EP 2006008726W WO 2007028608 A3 WO2007028608 A3 WO 2007028608A3
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WO
WIPO (PCT)
Prior art keywords
chips
nucleic acid
probes
detecting nitrogen
trpb
Prior art date
Application number
PCT/EP2006/008726
Other languages
English (en)
French (fr)
Other versions
WO2007028608A2 (de
Inventor
Stefan Evers
Joerg Feesche
Karl-Heinz Maurer
Thomas Schweder
Michael Hecker
Birgit Voigt
Britta Juergen
Le Thi Hoi
Original Assignee
Henkel Kgaa
Stefan Evers
Joerg Feesche
Karl-Heinz Maurer
Thomas Schweder
Michael Hecker
Birgit Voigt
Britta Juergen
Le Thi Hoi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel Kgaa, Stefan Evers, Joerg Feesche, Karl-Heinz Maurer, Thomas Schweder, Michael Hecker, Birgit Voigt, Britta Juergen, Le Thi Hoi filed Critical Henkel Kgaa
Priority to US11/991,761 priority Critical patent/US20100112552A1/en
Priority to EP06791904A priority patent/EP1924711A2/de
Publication of WO2007028608A2 publication Critical patent/WO2007028608A2/de
Publication of WO2007028608A3 publication Critical patent/WO2007028608A3/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Gegenstand der vorliegenden Anmeldung sind Nukleinsäure-bindende Chips zur Überwachung von Bioprozessen unter spezieller Ausrichtung auf die Detektion von Stickstoffmangelzuständen. Sie tragen Sonden für mindestens drei der folgenden 50 Gene: kdgR, citA, htrA, ycnl, yppF, trpB, ggt, alsR, glnA, nrgA, yciC, yvtA, nrgB, ycnJ, glnR, yvIA, yncE, yvlB, trpF, ydfS, trpD, ycnK, trpB, trpC, nasD, ycdH, nasC, nasB, trpE, pckA, nasF, yrkC und tnrA oder Homologen zu SEQ ID NO. 91 , 41 , 53, 19, 55, 47, 21 , 17, 9, 85, 45, 49, 95, 63, 15, 93 oder 81 bei maximal 80 für den Stickstoff-Stoffwechsel spezifischen unterschiedlichen Sonden. Ferner betrifft diese Anmeldung die Verwendung entsprechender Gensonden, insbesondere auf solchen Chips, beziehungsweise entsprechende Verfahren und Verwendungsmöglichkeiten.
PCT/EP2006/008726 2005-09-08 2006-09-07 Nukleinsäure-bindende chips zur detektion von stickstoffmangelzuständen im rahmen der bioprozesskontrolle WO2007028608A2 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US11/991,761 US20100112552A1 (en) 2005-09-08 2006-09-07 Nucleic acid-binding chips for detecting nitrogen deficiencies as part of bioprocess control
EP06791904A EP1924711A2 (de) 2005-09-08 2006-09-07 Nukleinsäure-bindende chips zur detektion von stickstoffmangelzuständen im rahmen der bioprozesskontrolle

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005042572.0 2005-09-08
DE102005042572A DE102005042572A1 (de) 2005-09-08 2005-09-08 Nukleinsäure-bindende Chips zur Detektion von Stickstoffmangelzuständen im Rahmen der Bioprozeßkontrolle

Publications (2)

Publication Number Publication Date
WO2007028608A2 WO2007028608A2 (de) 2007-03-15
WO2007028608A3 true WO2007028608A3 (de) 2007-06-21

Family

ID=37693253

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/008726 WO2007028608A2 (de) 2005-09-08 2006-09-07 Nukleinsäure-bindende chips zur detektion von stickstoffmangelzuständen im rahmen der bioprozesskontrolle

Country Status (4)

Country Link
US (1) US20100112552A1 (de)
EP (1) EP1924711A2 (de)
DE (1) DE102005042572A1 (de)
WO (1) WO2007028608A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1772522A1 (de) * 2005-10-04 2007-04-11 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Kontrolle der Konservierung mit Biomarkern

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002029113A2 (en) * 2000-10-06 2002-04-11 Novozymes Biotech, Inc. Methods for monitoring multiple gene expression

Family Cites Families (8)

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Publication number Priority date Publication date Assignee Title
US7115364B1 (en) * 1993-10-26 2006-10-03 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
DE19916867A1 (de) * 1999-04-14 2000-10-19 Fraunhofer Ges Forschung Anordnung und Verfahren zur Herstellung planarer Arrays mit immobilisierten Molekülen
DE19916921A1 (de) * 1999-04-14 2000-10-19 Fraunhofer Ges Forschung Elektrisches Sensorarray
EP1313856B1 (de) * 2000-08-31 2007-03-21 Degussa GmbH Citb gen aus corynebakterien und seine verwendung zur herstellung von l-aminosäuren
AU2001285916A1 (en) * 2000-09-09 2002-03-22 Degussa A.G. Nucleotide sequences which code for the clpc gene
DE10058394C1 (de) * 2000-11-24 2002-07-11 Siemens Ag Verfahren für die biochemische Analytik und zugehörige Anordnung
DE10242433A1 (de) * 2002-09-11 2004-03-25 Henkel Kgaa DNA-Chips zur Bioprozeßkontrolle
DE102004061664A1 (de) * 2004-12-22 2006-07-06 Henkel Kgaa Nukleinsäure-bindende Chips zur Detektion von Phosphatmangelzuständen im Rahmen der Bioprozesskontrolle

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002029113A2 (en) * 2000-10-06 2002-04-11 Novozymes Biotech, Inc. Methods for monitoring multiple gene expression

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
"Platform GPL188: Sigma Genosys Panorama Bacillus subtilis Gene Array", GEO, 20 December 2002 (2002-12-20), XP002373594 *
BOER VIKTOR M ET AL: "The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 278, no. 5, 31 January 2003 (2003-01-31), pages 3265 - 3274, XP002418951, ISSN: 0021-9258 *
FISHER S H: "REGULATION OF NITROGEN METABOLISM IN BACILLUS SUBTILIS: VIVE LA DIFFERENCEÜ", MOLECULAR MICROBIOLOGY, BLACKWELL SCIENTIFIC, OXFORD, GB, vol. 32, no. 2, 1999, pages 223 - 232, XP000982368, ISSN: 0950-382X *
GYANESHWAR PRASAD ET AL: "Sulfur and nitrogen limitation in Escherichia coli K-12: Specific homeostatic responses", JOURNAL OF BACTERIOLOGY, vol. 187, no. 3, February 2005 (2005-02-01), pages 1074 - 1090, XP002418950, ISSN: 0021-9193 *
HAYES ANDREW ET AL: "Hybridization array technology coupled with chemostat culture: Tools to interrogate gene expression in Saccharomyces cerevisiae", METHODS (ORLANDO), vol. 26, no. 3, March 2002 (2002-03-01), pages 281 - 290, XP002418949, ISSN: 1046-2023 *
HUA QIANG ET AL: "Analysis of gene expression in Escherichia coli in response to changes of growth-limiting nutrient in chemostat cultures.", APPLIED AND ENVIRONMENTAL MICROBIOLOGY APR 2004, vol. 70, no. 4, April 2004 (2004-04-01), pages 2354 - 2366, XP002418952, ISSN: 0099-2240 *
HUESER ANDREA T ET AL: "Development of a Corynebacterium glutamicum DNA microarray and validation by genome-wide expression profiling during growth with propionate as carbon source.", JOURNAL OF BIOTECHNOLOGY, vol. 106, no. 2-3, 19 December 2003 (2003-12-19), pages 269 - 286, XP002418953, ISSN: 0168-1656 *
JARMER H ET AL: "Transcriptome analysis documents induced competence of Bacillus subtilis during nitrogen limiting conditions", FEMS MICROBIOLOGY LETTERS, AMSTERDAM, NL, vol. 206, no. 2, 10 January 2002 (2002-01-10), pages 197 - 200, XP002392928, ISSN: 0378-1097 *

Also Published As

Publication number Publication date
WO2007028608A2 (de) 2007-03-15
US20100112552A1 (en) 2010-05-06
DE102005042572A1 (de) 2007-03-15
EP1924711A2 (de) 2008-05-28

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