WO2007005026A1 - Système thérapeutique portatif de refroidissement - Google Patents

Système thérapeutique portatif de refroidissement Download PDF

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Publication number
WO2007005026A1
WO2007005026A1 PCT/US2005/023857 US2005023857W WO2007005026A1 WO 2007005026 A1 WO2007005026 A1 WO 2007005026A1 US 2005023857 W US2005023857 W US 2005023857W WO 2007005026 A1 WO2007005026 A1 WO 2007005026A1
Authority
WO
WIPO (PCT)
Prior art keywords
output device
control unit
thermal control
portable therapeutic
cooling system
Prior art date
Application number
PCT/US2005/023857
Other languages
English (en)
Inventor
Keith Patrick Heaton
Original Assignee
Kci Licensing, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kci Licensing, Inc. filed Critical Kci Licensing, Inc.
Priority to EP05769362A priority Critical patent/EP1898850A4/fr
Priority to JP2008519251A priority patent/JP2008544805A/ja
Priority to AU2005334100A priority patent/AU2005334100B2/en
Priority to PCT/US2005/023857 priority patent/WO2007005026A1/fr
Priority to CN2005800509951A priority patent/CN101217924B/zh
Priority to CA2613890A priority patent/CA2613890C/fr
Publication of WO2007005026A1 publication Critical patent/WO2007005026A1/fr
Priority to HK08109402.5A priority patent/HK1116657A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0001—Body part
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0001—Body part
    • A61F2007/0002—Head or parts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0054—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water
    • A61F2007/0056—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water for cooling
    • A61F2007/0057—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water for cooling of gas, e.g. air or carbon dioxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0059—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit
    • A61F2007/0063—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit for cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
    • A61F2007/0075—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating using a Peltier element, e.g. near the spot to be heated or cooled
    • A61F2007/0076—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating using a Peltier element, e.g. near the spot to be heated or cooled remote from the spot to be heated or cooled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
    • A61F2007/0077—Details of power supply
    • A61F2007/0078—Details of power supply with a battery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0086—Heating or cooling appliances for medical or therapeutic treatment of the human body with a thermostat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0091—Heating or cooling appliances for medical or therapeutic treatment of the human body inflatable

Definitions

  • the present invention relates generally to a cooling system and more particularly, but not by way of limitation, to a portable therapeutic cooling system utilizing gas that provides a mild hypothermic effect adapted to be used immediately or as soon as possible following a traumatic event.
  • Temperature is an important variable in determining the amount of neural damage resulting from an ischemic ' attack (Dietrich et al, 1990). Clinically, temperature is now deemed a significant, independent risk factor for stroke (Reith et al, 1996), as well as a contributing risk factor to other risk factors for stroke such as hypertension, cigarette
  • Cooling pillows for the head and neck region have also been devised to decrease the body temperature of the patient (Tsutomu & Koji, 1998 in Japanese Patent Publication 09-072152; Katsumitsu & Shinichi, 2000 in Japanese Patent Publication 10-250455). These devices are often bulky and require specialized knowledge of the device in order to operate the device effectively.
  • prior devices are relatively bulky and uncomfortable.
  • a device that is comfortable and respectful of the subject's physical condition.
  • a subject In the case of injury to the brain induced by stroke, or in the case of cardiac arrest, a subject may be transported to a hospital over a long distance.
  • Many such subjects are elderly and would find it uncomfortable, traumatic or even undignified to be encased in such devices as are known.
  • Particularly, bulky helmet-like devices with circulating fluids or large cooling inserts are inappropriate for this reason.
  • the present invention fulfills these and other needs through the development of a portable therapeutic cooling system that utilizes convective cooling and re-circulated air to efficiently, safely, and effectively cool the head and body of the patient, clothed or not, immediately after a significant or life threatening health event, such as a cardiac arrest or stroke.
  • a portable therapeutic cooling system that utilizes convective cooling and re-circulated air to efficiently, safely, and effectively cool the head and body of the patient, clothed or not, immediately after a significant or life threatening health event, such as a cardiac arrest or stroke.
  • FIGURE 1 is a top partial cutaway view of a portable therapeutic cooling system is shown according to one embodiment of the present invention
  • FIGURE 2 is a top-plan view of a portable therapeutic cooling system in accordance with another embodiment of the present invention.
  • FIGURE 3 is a schematic diagram of a portable therapeutic cooling system according to one embodiment of the present invention.
  • FIGURE 4 is another schematic diagram of a portable therapeutic cooling system according to one embodiment of the present invention.
  • FIGURE 5 is another schematic diagram of an alternate cooling system used with a portable therapeutic system according to one embodiment of the present invention.
  • FIGURE 6 is another schematic diagram of a portable therapeutic cooling system according to one embodiment of the present invention.
  • FIGURE 7 is another schematic diagram of a portable therapeutic cooling system according to one embodiment of the present invention. DETAILED DESCRIPTION OF THE INVENTION
  • the present invention overcomes the deficiencies of the prior art through the development of a portable therapeutic cooling system adapted to be applied as soon as possible to the patient after the health event, that is adapted to be used in transitory settings, such as in an ambulance, or in a patient's immediate area, such as the patient's home, that is adapted to be operated by a bystander, paramedic, or other nearby personnel and can be used effectively on clothed patients.
  • the cooling system 100 includes an inflatable unitary head and body suit 102 coupled to a cooling unit 104.
  • the inflatable suit 102 is preferably composed of disposable material capable of allowing air to circulate through the inflatable suit 102, but non-disposable embodiments are contemplated to be within the scope of this invention.
  • the inflatable suit 102 is adapted to be sealed about the patient along a seam 106, such as by a zipper, buttons or other equivalent fastening means, although the convective nature of the heat transfer from the inflatable suit 102 to the patient does not require the inflatable suit 102 to be sealed about the patient in order for the patient to be cooled.
  • the suit 102 may be designed in small, medium, large and extra-large configurations or otherwise sized to shape pediatric patients, depending on the requirements of the user.
  • the suit 102 is suitably adapted to circulate air throughout the suit 102 while preventing the air from escaping to the environment, and has an air inlet port 108 and an air outlet port 110.
  • the air inlet port 108 is preferably connected to the cooling unit 104 via hoses or the like, which delivers cooled air from a source to the suit 102.
  • the air outlet port 110 is adapted to deliver air circulated through the suit 102 to the cooling unit 104 via hoses or the like for re-circulation into the suit 102 via the air inlet port 108.
  • the suit 102 is adapted to deliver cooling to the patient via convective heat transfer.
  • the suit 102 is further adapted to provide cooling to critical areas such as the neck,
  • the cooling unit 104 is either activated, if already connected to the suit, or connected to the air inlet port 108 and air outlet port 110 and then activated. Cool air is then directed to flow throughout the suit and convectively cool the patient's body by encompassing a significant percentage of the patient's entire body.
  • the recirculation feature of the suit 102 allows the system to operate efficiently and maintain the air at a predetermined cooling temperature.
  • a power source such as a 12 V. D.C. device — such as those available in ambulances — or other power sources including A.C. current-delivering devices may be suitably used to power the cooling unit 104.
  • a battery may be included in the cooling unit 104.
  • FIGURE 2 a top-plan view of a portable therapeutic cooling system 200 in accordance with another embodiment of the present invention is shown.
  • the portable therapeutic cooling system 200 is adapted to be placed about a patient's head and neck only, and cool the head and neck, including the carotid artery.
  • a hood 202 is provided connected to a cooling unit 204.
  • the hood 202 provides convective airflow through the hood 202 around the scalp of a patient in a closed loop, and further includes means to provide a transmission path for the air in an effort to cool the patient's brain, such as emissary veins in an open loop.
  • the hood 202 further includes stretchers 206 in the fabric structure thereof to provide space for allowing circulation of air around the scalp.
  • An air inlet port 208 is provided on the hood 202 for connecting a delivery tube 210 to the cooling unit 204.
  • cold air is delivered through the delivery tube 210 and into the hood 204, where it circulates around the head and neck area of the patient and provides convective cooling.
  • FIGURE 3 a schematic diagram of a portable therapeutic cooling system 300 is shown according to one embodiment of the present invention.
  • a control unit 302 is provided, which receives temperature input from a temperature sensor 303 between a heat exchanger 304 and the output devices, such as the hood 306 and suit 308.
  • the control unit 302 provides a speed control signal to an air blower 310, which, in turn, blows air over the heat exchanger 304 in communication with a cooling source 314.
  • a pressure sensor 316 may be provided between the air blower 310 and heat exchanger 304 and connected to the control unit 302 to assist the control unit 302 in determining the appropriate speed of the air blower 310.
  • control unit 302 when the control unit 302 is activated, it first determines the temperature from the temperature sensor 303 and the pressure from the pressure sensor 316. The control unit 302 then provides a signal to the air blower 310, which activates and blows air over the heat exchanger 304. The resulting air is then transmitted to either the hood 306 or the suit 308, depending on which device is connected to the system 300.
  • FIGURE 4 another schematic diagram of a portable therapeutic cooling system 400 according to one embodiment of the present invention is shown.
  • the cooling system 400 is provided with a peltier element 402 in combination with a heat exchanger for controlling the temperature of air passing therethrough.
  • a control unit 404 is connected to an air blower 406, a diverter valve 408 and a temperature sensor 410.
  • the diverter valve 408 is prepositioned between the air blower 406 and the peltier element 402 and directs airflow accordingly over the hot side or cold side of the peltier element 402 based on the control unit 404 and the requirement to warm or cool.
  • the temperature sensor 410 is placed downstream from the peltier element 402 and upstream of either the hood 412 or suit 414, depending on the configuration of the system 400. As such, the cooling system 400 provides sufficient thermal control to the patient when using the hood 412 or suit 414. It is to be appreciated that the hood 412 or suit 414 may be inflatable, and that the hood 412 or suit 414 may be unitary.
  • FIGURE 5 another schematic diagram of an alternate cooling supply 500 used with the portable therapeutic system of FIGURE 6 is shown.
  • the alternate cooling supply 500 is compressed gas, which is often stored in containers such as container 502.
  • the container 502 is connected to a proportional valve 504, which in turn is connected to a control unit (not shown), and may be connected to a heat exchanger (not shown).
  • the valve 504 may be connected to a dilution device (not shown) to dilute the compressed gas with air. Liquid air may be used as the compressed gas.
  • FIGURE 6 is another schematic diagram of a portable therapeutic cooling system 600 according to one embodiment of the present invention.
  • the system 600 includes a control unit 602, an air mover 604 connected to the control unit 602 and to either a hood 606 or suit 608 as desired.
  • a compressed gas container 610 is further provided connected to a valve 612.
  • the valve 612 is connected to the control unit 602, and to an area upstream of the air mover 604 before the hood 606 or suit 608.
  • a temperature sensor 614 is provided in
  • control unit 602 the same area and connected to the control unit 602 for providing temperature data to the control unit 602 during operation.
  • air is re-circulated from the suit 608 to the air mover 604 to increase the efficiency of the system.
  • the compressed gas such as liquid air
  • the compressed gas provides a cool stream of air to the hood 606 or suit 612, and thereby eliminates the need for a heat exchanger.
  • Flow from the container 610 is controlled by the valve 612, which in turn is directed to increase or decrease the airflow therethrough by the control unit 602.
  • air may comprise any gas, including fluid, capable of providing cooling to the output device.
  • the hood 606 or suit 608 may be inflatable, and that the hood 606 or suit 612 may be unitary.
  • FIGURE 7 another schematic diagram of an alternate portable therapeutic cooling system 700 is shown.
  • a control unit 702 is provided, which receives temperature input from a temperature sensor 703 between a heat exchanger 704 and the output devices, such as the hood 706 and suit 708.
  • the control unit 702 provides a speed control signal to an air blower 710, which, in turn, blows air over a heat exchanger 704 in communication with ice 712.
  • a re-circulation line may be provided between the suit 708 and the air blower 710, which may be a pump or the like, to increase the cooling efficiency of the system 700.
  • the ice 712 provides a generally readily available cooling source for users of the system 700 in the event of emergency.
  • each of the embodiments shown in the FIGURES are portable, and adapted to be disposable, though not limited to this feature.
  • the embodiments shown herein provide an efficient, portable therapeutic cooling system that may be conveniently used by bystanders, paramedics, or anyone who is available to assist after a patient undergoes a significant or life threatening health event, with little instruction required.
  • the cooling disclosed herein is typical of that of a convective cooling system, though conductive, radiation or alternate heat-transfer mechanisms adapted to be portable are contemplated to be within the scope of this invention.
  • Both the hood and suit in the embodiments shown is adapted to be disposable to avoid the necessary decontamination procedures that would normally accommodate re-use of these devices.
  • air when the term air is used, it encompasses any gas, including a liquid, capable of provided cooling to the respective output device (e.g. the hood,

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Thermal Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)

Abstract

L’invention a pour objet un système thérapeutique de refroidissement portatif et jetable qui exploite le refroidissement par convection et la remise en circulation de l’air pour refroidir efficacement, puissamment et en toute sécurité la tête et le corps d’un patient, habillé ou non, après un épisode susceptible de mettre sa vie en danger tel qu’un arrêt cardiaque ou un accident vasculaire cérébral.
PCT/US2005/023857 2005-07-05 2005-07-05 Système thérapeutique portatif de refroidissement WO2007005026A1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
EP05769362A EP1898850A4 (fr) 2005-07-05 2005-07-05 Système thérapeutique portatif de refroidissement
JP2008519251A JP2008544805A (ja) 2005-07-05 2005-07-05 携帯型治療用冷却システム
AU2005334100A AU2005334100B2 (en) 2005-07-05 2005-07-05 Portable therapeutic cooling system
PCT/US2005/023857 WO2007005026A1 (fr) 2005-07-05 2005-07-05 Système thérapeutique portatif de refroidissement
CN2005800509951A CN101217924B (zh) 2005-07-05 2005-07-05 便携式治疗用冷却系统
CA2613890A CA2613890C (fr) 2005-07-05 2005-07-05 Systeme therapeutique portatif de refroidissement
HK08109402.5A HK1116657A1 (en) 2005-07-05 2008-08-23 Portable therapeutic cooling system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2005/023857 WO2007005026A1 (fr) 2005-07-05 2005-07-05 Système thérapeutique portatif de refroidissement

Publications (1)

Publication Number Publication Date
WO2007005026A1 true WO2007005026A1 (fr) 2007-01-11

Family

ID=37604773

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/023857 WO2007005026A1 (fr) 2005-07-05 2005-07-05 Système thérapeutique portatif de refroidissement

Country Status (7)

Country Link
EP (1) EP1898850A4 (fr)
JP (1) JP2008544805A (fr)
CN (1) CN101217924B (fr)
AU (1) AU2005334100B2 (fr)
CA (1) CA2613890C (fr)
HK (1) HK1116657A1 (fr)
WO (1) WO2007005026A1 (fr)

Cited By (11)

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US8236038B2 (en) 2006-04-20 2012-08-07 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Method and apparatus of noninvasive, regional brain thermal stimuli for the treatment of neurological disorders
US8425583B2 (en) 2006-04-20 2013-04-23 University of Pittsburgh—of the Commonwealth System of Higher Education Methods, devices and systems for treating insomnia by inducing frontal cerebral hypothermia
WO2013122350A1 (fr) * 2012-02-15 2013-08-22 경북대학교 산학협력단 Dispositif de refroidissement cérébral portable
US8608696B1 (en) 2009-02-24 2013-12-17 North Carolina State University Rapid fluid cooling devices and methods for cooling fluids
US9211212B2 (en) 2006-04-20 2015-12-15 Cerêve, Inc. Apparatus and method for modulating sleep
US9492313B2 (en) 2006-04-20 2016-11-15 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Method and apparatus of noninvasive, regional brain thermal stimuli for the treatment of neurological disorders
US10058674B2 (en) 2013-01-02 2018-08-28 Ebb Therapeutics, Inc. Systems for enhancing sleep
CN110478112A (zh) * 2019-09-11 2019-11-22 武汉亚格光电技术股份有限公司 一种医疗用灭菌空气皮肤冷却系统
US10588778B2 (en) 2016-03-21 2020-03-17 Stryker Corporation Mobile thermal system
SE543504C2 (en) * 2017-03-15 2021-03-09 Chriah Ab Portable cooling device comprising a Peltier element
US11684510B2 (en) 2006-04-20 2023-06-27 University of Pittsburgh—of the Commonwealth System of Higher Education Noninvasive, regional brain thermal stimuli for the treatment of neurological disorders

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JP2014529315A (ja) 2011-07-25 2014-11-06 ニューロセーブ インコーポレイテッド 選択的脳冷却のための非侵襲的なシステム、機器、および方法
CN102512734B (zh) * 2011-12-29 2013-09-11 武汉大学 一种便携式冰盐水自动亚低温仪
CN104921929B (zh) * 2015-07-02 2017-03-01 中国人民解放军第四军医大学 一种可调节激光治疗后面部冷却的面罩
CA3006245C (fr) * 2015-09-30 2019-04-02 Wesam SABBAHI Systeme d'ecoulement d'air et procede de therapie par circulation d'air
CN110169619A (zh) * 2019-06-17 2019-08-27 厦门国仪科学仪器有限公司 一种冷却头盔及头皮冷却系统
CN112229092A (zh) * 2020-10-19 2021-01-15 中国科学院理化技术研究所 液态空气储能冷热气联供系统

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AU2005334100A1 (en) 2007-01-11
EP1898850A4 (fr) 2010-11-10
CN101217924B (zh) 2010-10-13
EP1898850A1 (fr) 2008-03-19
CA2613890C (fr) 2013-06-25
JP2008544805A (ja) 2008-12-11
HK1116657A1 (en) 2009-01-02
CA2613890A1 (fr) 2007-01-11
AU2005334100B2 (en) 2012-01-19
CN101217924A (zh) 2008-07-09

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