WO2006085346A1 - Mixtures of fatty acid glycerides from c1 to c22 to improve zootechnical performances and/or the health of the intestine of animals - Google Patents

Mixtures of fatty acid glycerides from c1 to c22 to improve zootechnical performances and/or the health of the intestine of animals Download PDF

Info

Publication number
WO2006085346A1
WO2006085346A1 PCT/IT2005/000601 IT2005000601W WO2006085346A1 WO 2006085346 A1 WO2006085346 A1 WO 2006085346A1 IT 2005000601 W IT2005000601 W IT 2005000601W WO 2006085346 A1 WO2006085346 A1 WO 2006085346A1
Authority
WO
WIPO (PCT)
Prior art keywords
mixtures
monoglycerides
diglycerides
glycerides
fatty acids
Prior art date
Application number
PCT/IT2005/000601
Other languages
French (fr)
Inventor
Fernando Cantini
Original Assignee
Fernando Cantini
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fernando Cantini filed Critical Fernando Cantini
Priority to BRPI0520019-9A priority Critical patent/BRPI0520019A2/en
Priority to US11/883,952 priority patent/US20080268094A1/en
Priority to MX2007009582A priority patent/MX2007009582A/en
Priority to EP05805811A priority patent/EP1863356A1/en
Priority to JP2007554744A priority patent/JP2008529521A/en
Publication of WO2006085346A1 publication Critical patent/WO2006085346A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/04—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils
    • C11C3/06—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils with glycerol
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/02—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fatty acids with glycerol
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Definitions

  • the present invention relates to the production and/or use of mixtures of monoglycerides, diglycerides and triglycerides of fatty acids from Ci to C 22 to administer to livestock and pets, in order to improve performances and the health of the intestine.
  • the invention relates to the production and/or use of mixtures of monoglycerides, diglycerides and triglycerides of fatty acids from Ci to C1 2 , charged with improving the health of the intestinal tract of animals, and of mixtures of monoglycerides, diglycerides and triglycerides of fatty acids from Ci to C 22 , charged with controlling the quantity and quality of depot fat, satisfying specific nutritional requirements of the various animal species in various ages and improving the health of the intestine.
  • glycerides are produced by the reaction of glycerol with fatty acids from Ci to C2 2 previously mixed together, or by the reaction of glycerol with mixtures of fatty acids from Ci to C 22 and/or with vegetable oils and/or with animal fats.
  • the present invention contributes towards solving two important problems in livestock feeding, namely: - health of the intestinal tract, control of the quantity and quality of depot fats. This is obtained through the production and/or use, in animal feeding, of:
  • butyric acid (C 4 :0) is efficacious as nutrient of the intestinal mucosa, as stimulator of intestinal trophism in terms of renewal of basal cells and increase in the density and length of villi, as antibacterial/bacteriostatic agent against pathogenic microorganisms, including Clostridium acetobutylicum, Escherichia coli, streptococcus cremoris, salmonella sp, brachyspira hyodysenteriae etc., and as modulator of the intestinal flora as it promotes the development of "useful" microorganisms such as lactobacilli.
  • butyric acid is found in the milk of cows, sows and other species.
  • butyric acid is commonly produced in the intestine subsequent to digestive-metabolic degradation of fibers and carbohydrates.
  • butyric acid from its bacteriostatic effect to its ameliorative effect on zootechnical yield as stimulator of the growth of intestinal villi
  • livestock species pest, pigs, rabbits, ruminants
  • zootechnical industry has for some time been involved in implementing methods that allow sources of butyric acid to be added to the diets of animals at costs that permit their use at efficacious doses in rearing of livestock.
  • Another limitation is represented by the high costs of products which although containing butyric acid are odorless, but generally also very expensive, such as microencapsulated products.
  • the unpleasant and persistent odor of butyric acid are caused by the extremely high volatility of this fatty acid.
  • the volatility of the butyric acid is drastically limited by increasing the molecular weight due to combination of said butyric acid with glycerol.
  • the new glycerides containing butyric acid have a slight odor, not unpleasant and not persistent.
  • the production process employed to produce the new glycerides does not require forms of encapsulation and does not require aromatization, thereby making it possible to obtain a final product at limited costs.
  • the glycerides represent an interesting solution to another problem which arises when the butyric acid requires to be carried, in its undissociated form, to intestinal tracts where it is required to perform its bacteriostatic function and stimulate the trophism of basal cells.
  • the butyric acid it is, in fact, administered in the form of glyceride, or as fatty acid bound to glyceride.
  • the glycerol-organic acid bond is not influenced by the pH of the stomach (gastric by-pass) and the glycerides reach the intestine integral, where the gradual process to release the fatty acids through the action of lipases takes place.
  • the fatty acids in this case butyric acid, is released by enzymatic attack, in its undissociated form, as the glyceride advances in the intestine, exerting its efficacy through time and in the various intestinal tracts (slow release effect).
  • the decomposition process of the glycerides can in this case be compared to the process to which the glycerides forming the lipid fraction of the milk of cows, sows and other species are subjected.
  • mixtures of glycerides forming the subject of the present invention offer important advantages not only for their efficacy in carrying, in the various intestinal tracts, specific fatty acids important for antibacterial action, health and trophism of the intestine, but also for their specifically nutritional value.
  • the mixtures of fatty acid glycerides from Ci to C-22 forming the object of the present invention have three aspects worthy of notice: A) the glycerides in question are composed of monoglycerides, diglycerides and triglycerides in proportions which exert an emulsioning action suitable to promote absorption of the fatty acids contained in glycerides and also of those other fatty acids contained in the lipid fraction of the diet; B) as the fatty acids in the monoglycerides and in the diglycerides in question are prevalently (over 80%) in position 1 and 3 in the molecule, this peculiarity means that these monoglycerides and diglycerides (once absorbed) have difficulty in being reesterified into triglycerides and are therefore used by the animal prevalently for energy purposes; consequently, it is possible to program the new glycerides as a function of the greater or lesser quantity of depot fats required, predetermining the percentage of monoglycerides and diglycerides of the mixtures by do
  • the percentages of monoglycerides, diglycerides and triglycerides of the fatty acids can vary in the following proportions:
  • a mixture of this type has proved particularly efficacious in poultry in stimulating the growth of intestinal villi (with consequent improvement in the absorption of nutrients and in obtaining a high antibacterial/bacteriostatic effect).
  • the glycerides in question - in particular from Ci to C- 12 - can also be utilized carried in the drinking water destined for the animals.
  • fatty acids from Ci to C 12 represent a source of energy which can be assimilated even if there is a scarcity of biliary salts (typical in young animals).
  • the percentage of butyric acid in these mixtures of glycerides can vary from 5% to 100%.
  • the glycerides structured as indicated above allow butyric acid (which performs antibacterial/bacteriostatic functions, functions of modulation of the intestinal flora and stimulation of the growth of intestinal villi) to be administered simultaneously to oleic acid (important for its high digestibility and beneficial effects on the metabolism of lipids) and/or to linoleic acid, an essential fatty acid not synthesized by the organism but indispensable for its functions, in particular in young animals.
  • the percentage of butyric acid in these mixtures normally varies from 2% to 15%, the percentage of oleic acid from 40% to 70% and the percentage of linoleic acid from 10% to 60%.
  • glycerides thus structured allow butyric acid (which performs antibacterial/bacteriostatic functions, functions of modulation of the intestinal flora and stimulation of the growth of intestinal villi) to be administered simultaneously to palmitic acid and to stearic acid. In this way, in finishing, in addition to covering specific physiological requirements, the subcutaneous fat of the animal destined for slaughter is given consistency and oxidation stability.
  • butyric acid in these mixtures normally varies from 2% to 20%, the percentage of palmitic acid from 10% to 50% and the percentage of stearic acid from 2% to 70%.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)

Abstract

The present invention relates to the production and/or use of mixtures of monoglycerides, diglycerides and triglycerides of fatty acids from C1 to C22 to administer to livestock and pets, in order to improve performances and the health of the intestine. The glycerides are produced by the reaction of glycerol with mixtures of fatty acids from C1 to C22 or by the reaction of glycerol with mixtures of fatty acids from C1 to C22 and/or vegetable oils and/or animals fats. In one embodiment, a minimum of 5% and a maximum of 100% of butyric acid is provided.

Description

"MIXTURES OF FATTY ACID GLYCERIDES FROM Ci TO C22 TO IMPROVE ZOOTECHNICAL PERFORMANCES AND/OR THE HEALTH OF THE INTESTINE OF ANIMALS"
DESCRIPTION The present invention relates to the production and/or use of mixtures of monoglycerides, diglycerides and triglycerides of fatty acids from Ci to C22 to administer to livestock and pets, in order to improve performances and the health of the intestine.
In particular, the invention relates to the production and/or use of mixtures of monoglycerides, diglycerides and triglycerides of fatty acids from Ci to C12, charged with improving the health of the intestinal tract of animals, and of mixtures of monoglycerides, diglycerides and triglycerides of fatty acids from Ci to C22, charged with controlling the quantity and quality of depot fat, satisfying specific nutritional requirements of the various animal species in various ages and improving the health of the intestine.
These glycerides are produced by the reaction of glycerol with fatty acids from Ci to C22 previously mixed together, or by the reaction of glycerol with mixtures of fatty acids from Ci to C22 and/or with vegetable oils and/or with animal fats.
Other characteristics of the invention are defined in the claims following the present description.
The present invention contributes towards solving two important problems in livestock feeding, namely: - health of the intestinal tract, control of the quantity and quality of depot fats. This is obtained through the production and/or use, in animal feeding, of:
- mixtures of monoglycerides, diglycerides and triglycerides of short and medium chain fatty acids from Ci to C12 to improve the health of the intestinal tract;
- mixtures of monoglycerides, diglycerides and triglycerides of fatty acids from Ci to C22 to control the quantity and quality of depot fats and improve the health of the intestinal iract. With regard to the health of the intestinal tract, recent directives on the subject of food safety provide for a gradual but unequivocal withdrawal of the use of antibiotics, and therefore the development of new products capable of combating pathogenic agents with "natural" mechanisms has become urgent and a priority.
It is useful to specify that for some time now it has been known that butyric acid (C4:0) is efficacious as nutrient of the intestinal mucosa, as stimulator of intestinal trophism in terms of renewal of basal cells and increase in the density and length of villi, as antibacterial/bacteriostatic agent against pathogenic microorganisms, including Clostridium acetobutylicum, Escherichia coli, streptococcus cremoris, salmonella sp, brachyspira hyodysenteriae etc., and as modulator of the intestinal flora as it promotes the development of "useful" microorganisms such as lactobacilli. In nature, butyric acid is found in the milk of cows, sows and other species. Moreover, butyric acid is commonly produced in the intestine subsequent to digestive-metabolic degradation of fibers and carbohydrates.
The beneficial effects of butyric acid (from its bacteriostatic effect to its ameliorative effect on zootechnical yield as stimulator of the growth of intestinal villi) are widely documented in the scientific literature with reference to various livestock species (poultry, pigs, rabbits, ruminants) and the zootechnical industry has for some time been involved in implementing methods that allow sources of butyric acid to be added to the diets of animals at costs that permit their use at efficacious doses in rearing of livestock.
In practice, there are in fact numerous limits to the use of products based on butyric acid. One of these is represented by the extremely unpleasant and persistent odor which also remains in some products in which it is contained (i.e. in the salts of butyric acid such as calcium or sodium butyrate).
Another limitation is represented by the high costs of products which although containing butyric acid are odorless, but generally also very expensive, such as microencapsulated products. The unpleasant and persistent odor of butyric acid are caused by the extremely high volatility of this fatty acid. In the new glycerides forming the object of the present invention the volatility of the butyric acid is drastically limited by increasing the molecular weight due to combination of said butyric acid with glycerol. The new glycerides containing butyric acid have a slight odor, not unpleasant and not persistent. Moreover, the production process employed to produce the new glycerides does not require forms of encapsulation and does not require aromatization, thereby making it possible to obtain a final product at limited costs.
With regard to elimination of the odor of butyric acid and limiting production costs, the glycerides to which the present invention refer solve the problem completely.
With regard to bacteriostatic efficacy, the glycerides, to which the present invention refers, represent an interesting solution to another problem which arises when the butyric acid requires to be carried, in its undissociated form, to intestinal tracts where it is required to perform its bacteriostatic function and stimulate the trophism of basal cells.
With the new glycerides the butyric acid it is, in fact, administered in the form of glyceride, or as fatty acid bound to glyceride.
The glycerol-organic acid bond is not influenced by the pH of the stomach (gastric by-pass) and the glycerides reach the intestine integral, where the gradual process to release the fatty acids through the action of lipases takes place. The fatty acids, in this case butyric acid, is released by enzymatic attack, in its undissociated form, as the glyceride advances in the intestine, exerting its efficacy through time and in the various intestinal tracts (slow release effect). The decomposition process of the glycerides can in this case be compared to the process to which the glycerides forming the lipid fraction of the milk of cows, sows and other species are subjected.
Other volatile fatty acids from Ci to Ci2 and contained, in nature, in foods (such as grapes, honey, wine, milk, butter, cheese, etc) also perform useful and selective antibacterial/bacteriostatic actions against strains of intestinal pathogens (such as E.coli, Oocysts, Clostridium - A - perfrigens, Salmonella enteritidis etc.), and can therefore contribute towards the health of the intestinal tract. Nonetheless, due to their volatile nature, these organic acids have problems of handling and administration common to those of butyric acid: they release strong and unpleasant odors, tend to evaporate if added as is (loose) to the feed, require carrier forms that guarantee their integrity during passage through the stomach (gastric by-pass), and release, in undissociated form, in the various tracts of the intestine. As in the case of butyric acid, by increasing the molecular weight, bonding with glycerol eliminates the problems of odor and volatility, and moreover, as it is not influenced by the pH of the stomach, it guarantees gastric by-pass and allows slow release of the undissociated fatty acid in the various intestinal tracts.
The mixtures of glycerides forming the subject of the present invention offer important advantages not only for their efficacy in carrying, in the various intestinal tracts, specific fatty acids important for antibacterial action, health and trophism of the intestine, but also for their specifically nutritional value. In particular, the mixtures of fatty acid glycerides from Ci to C-22 forming the object of the present invention have three aspects worthy of notice: A) the glycerides in question are composed of monoglycerides, diglycerides and triglycerides in proportions which exert an emulsioning action suitable to promote absorption of the fatty acids contained in glycerides and also of those other fatty acids contained in the lipid fraction of the diet; B) as the fatty acids in the monoglycerides and in the diglycerides in question are prevalently (over 80%) in position 1 and 3 in the molecule, this peculiarity means that these monoglycerides and diglycerides (once absorbed) have difficulty in being reesterified into triglycerides and are therefore used by the animal prevalently for energy purposes; consequently, it is possible to program the new glycerides as a function of the greater or lesser quantity of depot fats required, predetermining the percentage of monoglycerides and diglycerides of the mixtures by dosing the glycerol in the production process; C) in the glycerides containing butyric acid noteworthy synergy is always obtained between bacteriostatic efficacy and nutritional efficacy.
According to the invention, the percentages of monoglycerides, diglycerides and triglycerides of the fatty acids can vary in the following proportions:
- in mixtures with fatty acids from Ci to C-12 monoglycerides 0% - 86% diglycerides 0% - 86% triglycerides 0% - 100%
- in mixtures with fatty acids from C4 to C22 monoglycerides 7% - 86% diglycerides 7% - 86% triglycerides 7% - 86% By way of example, a mixture of glycerides of butyric acid can be composed of: monoglycerides of butyric acid = 20% - 25% diglycerides of butyric acid = 47% - 53% triglycerides of butyric acid = 25% - 30% A mixture of this type has proved particularly efficacious in poultry in stimulating the growth of intestinal villi (with consequent improvement in the absorption of nutrients and in obtaining a high antibacterial/bacteriostatic effect).
See Reports: - Short Title: BUTYRIC ACID ON PERFORMANCE AND CARCASS YIELD Scientific Section: METABOLISM AND NUTRITION - Effect of Butyric Acid on the Performance and Carcass Yield of Broiler Chickens - S. Leeson Department of Animal & Poultry Science, University of Guelph, ON, Canada NIG 2W1 ; H. Namkung, M. Antongiovanni Department of Animal Science University of Florence
(Italy), and F.H. Lee, Vetech Laboratories Inc. 131 Malcolm Road, Guelph, ON, Canada N1K 1AB.
Response of Broiler Chickens to Glycerides of Butyric Acid (GBA) Department of Animal Science University of Florence (Italy) Mauro Antongiovanni, Arianna Buccioni, Francesco Petacchi - 2004.
It has been ascertained that use of butyric acid in feed for poultry administered to the animals in the aforesaid chemical forms boosts the efficacy of vaccination against coccidiosis. In particular, in animals subjected to experimental infection with
Oocysts and Clostridium Perfrigens it has been shown that the growth of animals, to which butyric acid was administered in association with the vaccine against coccidiosis, was superior to those vaccinated (and infected) without the addition of butyric acid. See reports:
"Effect of butyric acid on the performance and carcass quality of broiler chickens" experiment 2 - Prof. Leeson of the University of Guelph - Canada - 2004.
"Preliminary results of a growth trial of broiler chickens with short chain fatty acids replacing the antibiotic avilamycin" Prof. M.
Antongiovanni - University of Florence - 2005.
The use in animal feed of glycerides as above containing from a minimum of 5% to a maximum of 100% of butyric acid, makes it possible to modulate the final quantity of butyric acid in the diet as a function of the total percentage of lipids added and of the specific nutritional requirements, or to boost the immune response against intestinal pathogenic agents (salmonella, E.coli, etc.) of the various species of farm animals.
The glycerides in question - in particular from Ci to C-12 - can also be utilized carried in the drinking water destined for the animals.
This makes it possible to obtain variation of the daily doses to be administered as a function of the specific and contingent requirements and also facilitates direct use by farm workers. Administration of the glycerides in question in the drinking water is made possible by the high monoglyceride and diglyceride content; in fact, monoglycerides and diglycerides are highly "polar" compounds able to make the glycerides in which they are contained easily water-dispersible.
Some examples of the use of products based on fatty acid glycerides are given hereunder. The use of glycerides containing both butyric acid and short and medium chain fatty acids from Ci to C12 in animal feed makes it possible to obtain, in addition to the antibacterial/bacteriostatic effect, an important nutritional value especially for young animals: in fact, fatty acids from Ci to C12 represent a source of energy which can be assimilated even if there is a scarcity of biliary salts (typical in young animals). The percentage of butyric acid in these mixtures of glycerides can vary from 5% to 100%.
The use of mixtures of butyric acid and Ciβ unsaturated fatty acids in the form of glycerides in animal feed has shown to have high digestibility, a high energy value and numerous and different actions. This can be found particularly in the case of butyric acid and oleic acid (Cis:1) and/or linoleic acid (Cis:2).
In fact, the glycerides structured as indicated above allow butyric acid (which performs antibacterial/bacteriostatic functions, functions of modulation of the intestinal flora and stimulation of the growth of intestinal villi) to be administered simultaneously to oleic acid (important for its high digestibility and beneficial effects on the metabolism of lipids) and/or to linoleic acid, an essential fatty acid not synthesized by the organism but indispensable for its functions, in particular in young animals.
The percentage of butyric acid in these mixtures normally varies from 2% to 15%, the percentage of oleic acid from 40% to 70% and the percentage of linoleic acid from 10% to 60%.
The use in animal feed of mixtures of butyric acid and saturated fatty acids C16-C18 in the form of glycerides offers numerous advantages: the glycerides thus structured allow butyric acid (which performs antibacterial/bacteriostatic functions, functions of modulation of the intestinal flora and stimulation of the growth of intestinal villi) to be administered simultaneously to palmitic acid and to stearic acid. In this way, in finishing, in addition to covering specific physiological requirements, the subcutaneous fat of the animal destined for slaughter is given consistency and oxidation stability.
The percentage of butyric acid in these mixtures normally varies from 2% to 20%, the percentage of palmitic acid from 10% to 50% and the percentage of stearic acid from 2% to 70%.
The above description can vary within the scope of the claims hereunder.

Claims

1. Production and/or use, in animal feed, of mixtures of monoglycerides, diglycerides and triglycerides of fatty acids from Ci to C22 to improve the health of the intestinal tract and to control the quantity and quality of depot fats.
2. Production and/or use as claimed in claim 1 , in animal feed, of mixtures of monoglycerides, diglycerides and triglycerides of fatty acids from Ci to C-12, aimed at improving the health of the intestinal tract of animals.
3. Production and/or use as claimed in claim 1 , in animal feed, of mixtures of monoglycerides, diglycerides and triglycerides of fatty acids from Ci to C-22, aimed at controlling the quantity and quality of depot fat, satisfying specific nutritional requirements of the various animal species in various ages and improving the health of the intestine.
4. Production and/or use of glycerides as claimed in claim 3, to improve the health of the intestinal tract, characterized in that the fatty acids are included in the range C1-C2-C3-C4-C-6-C8-C10-C12 with percentages of monoglycerides, diglycerides and triglycerides in the mixtures included in the following proportions: monoglycerides 0% - 86% diglycerides 0% - 86% triglycerides 0% - 100%
5. Production and/or use of glycerides as claimed in at least claim 1 , characterized by the reaction of glycerol with fatty acids from Ci to C22 previously mixed together, or with mixtures of fatty acids from Ci to C-22 and/or vegetable oils and/or animal fats.
6. Production and/or use of glycerides as claimed in at least claim 1 , to control the quantity and quality of depot fat, characterized in that the fatty acids are included in the range from Ci to C22, with percentages of monoglycerides, diglycerides and triglycerides included in the following proportions: monoglycerides 7% - 86% diglycerides 7% - 86% triglycerides 7% - 86% and the fatty acids in the monoglycerides and diglycerides are prevalently (approximately over 80%) in position 1 and 3 in the molecule, so that said monoglycerides and diglycerides tend to be used by the animal for energy purposes, as they have difficulty, once absorbed, in being reesterified into triglycerides.
7. Use of glycerides in poultry feed, as claimed in at least one of the previous claims, characterized in that the fatty acid present is only butyric acid.
8. Use of glycerides as claimed in at least claim 3, characterized in that the percentages of monoglycerides, diglycerides and triglycerides are included in the following ranges: monoglycerides of butyric acid 20% - 25% diglycerides of butyric acid 47% - 53% triglycerides of butyric acid 25% - 30%.
9. Use of glycerides as claimed in one or more of the previous claims, wherein a minimum of 5% and a maximum of 100% of butyric acid is provided.
10. Use of glycerides as claimed in one or more of the previous claims, wherein said glycerides are administered in the drinking water destined for animals, due to the high content of monoglycerides and diglycerides which are highly "polar" compounds and are therefore able to make the glycerides in which they are contained easily water- dispersible.
11. Use of glycerides as claimed in at least one of the previous claims, wherein - to obtain a synergic antibacterial/bacteriostatic, nutritional effect - both butyric acid and medium chain fatty acids from Ce to Ci2 are contained, the percentage of butyric acid in these mixtures of glycerides normally varying from 5% to 65%.
12. Use of mixtures of monoglycerides, diglycerides and triglycerides for animal feed, composed both of butyric acid and of Cis unsaturated fatty acids.
13. Use of mixtures of monoglycerides, diglycerides and triglycerides as claimed in at least claims 9 and/or 12, characterized in that the unsaturated fatty acids are composed mainly of oleic acid (Cis:1) and/or linoleic acid (Cis:2)
14. Use of mixtures of monoglycerides, diglycerides and triglycerides as claimed in claim 13, characterized in that the percentage of butyric acid contained therein varies from 2% to 15%, the percentage of oleic acid from 40% to 70% and the percentage of linoleic acid from 10% to 60%.
15. Use of mixtures of monoglycerides, diglycerides and triglycerides for animal feed, composed both of butyric acid and of Ci6- Ci8 saturated fatty acids.
16. Use of mixtures of monoglycerides, diglycerides and triglycerides as claimed in claim 15, characterized in that the percentage of butyric acid contained therein varies from 2% to 20%, the percentage of palmitic acid from 10% to 50% and the percentage of stearic acid from 2% to 70%.
17. Use of mixtures of monoglycerides, diglycerides and triglycerides as claimed in at least one of the previous claims, characterized in that they act in synergy with vaccines, in particular with vaccines against coccidiosis, with consequent synergic effect.
18. Use of mixtures of mono-di-triglycerides of fatty acids from Ci to C22 as ameliorators of zootechnical performances, inhibitors of pathogenic agents and to eliminate the odor of butyric acid, as described.
19. Method for producing glycerides, for the purposes indicated, characterized in that it includes the reaction of glycerol with mixtures of fatty acids from Ci to Oz2.
20. Method for producing glycerides, for the purposes indicated, characterized in that it includes the reaction of glycerol with mixtures of fatty acids from Ci to C22 and with vegetable oils.
21. Method for producing glycerides, for the purposes indicated, characterized in that it includes the reaction of glycerol with mixtures of fatty acids from Ci to C22 and with animal fats.
22. Method for producing glycerides, for the purposes indicated, characterized in that it includes the reaction of glycerol with vegetable oils.
23. Method for producing glycerides, for the purposes indicated, characterized in that it includes the reaction of glycerol with animal fats.
PCT/IT2005/000601 2005-02-14 2005-10-13 Mixtures of fatty acid glycerides from c1 to c22 to improve zootechnical performances and/or the health of the intestine of animals WO2006085346A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
BRPI0520019-9A BRPI0520019A2 (en) 2005-02-14 2005-10-13 fatty acid glyceride mixtures containing from 1 to 22 carbon atoms to improve zootechnical performance and / or animal intestinal tract health
US11/883,952 US20080268094A1 (en) 2005-02-14 2005-10-13 Mixtures of Fatty Acid Glycerides from C1 to C22 to Improve Zootechnical Performances and/or the Health of the Intestine of Animals
MX2007009582A MX2007009582A (en) 2005-02-14 2005-10-13 Mixtures of fatty acid glycerides from c1 to c22 to improve zootechnical performances and/or the health of the intestine of animals.
EP05805811A EP1863356A1 (en) 2005-02-14 2005-10-13 Mixtures of fatty acid glycerides from c1 to c22 to improve zootechnical performances and/or the health of the intestine of animals
JP2007554744A JP2008529521A (en) 2005-02-14 2005-10-13 Mixtures of C1-C22 fatty acid glycerides that improve the animal husbandry and health of animal intestines

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITFI2005A000024 2005-02-14
IT000024A ITFI20050024A1 (en) 2005-02-14 2005-02-14 LIPIDS FOR ANIMAL FEEDING

Publications (1)

Publication Number Publication Date
WO2006085346A1 true WO2006085346A1 (en) 2006-08-17

Family

ID=35658985

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IT2005/000601 WO2006085346A1 (en) 2005-02-14 2005-10-13 Mixtures of fatty acid glycerides from c1 to c22 to improve zootechnical performances and/or the health of the intestine of animals

Country Status (8)

Country Link
US (1) US20080268094A1 (en)
EP (1) EP1863356A1 (en)
JP (1) JP2008529521A (en)
CN (1) CN101119648A (en)
BR (1) BRPI0520019A2 (en)
IT (1) ITFI20050024A1 (en)
MX (1) MX2007009582A (en)
WO (1) WO2006085346A1 (en)

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2325854A1 (en) * 2008-03-19 2009-09-21 Norel, S.A. Method for recyling by-products by means of the reconstitution of fats useful in animal feeding-stuffs
FR2933406A1 (en) * 2008-07-07 2010-01-08 Rhodia Poliamida E Especialidades Ltda PROCESS FOR OBTAINING GLYCERIDES BY ESTERIFYING ALCOHOL AND CARBOXYLIC ACID
ITPD20080352A1 (en) * 2008-11-28 2010-05-29 Sila S R L PROCESS FOR THE PRODUCTION OF A COMPOUND OF N-BUTIRRIC ACID IN MICROCAPSULATED FORM, INTENDED FOR ANIMAL OR HUMAN POWER
ITFI20090050A1 (en) * 2009-03-16 2010-09-17 Fernando Cantini COMPOSITIONS CONTAINING MONOGLICERIDES OF ORGANIC ACIDS FROM C1 TO C7 AND GLYCEROL, THEIR PREPARATION AND USE AS ANTIBACTERIALS IN THE ZOOTECHNY.
US8343753B2 (en) 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
WO2015057121A1 (en) * 2013-10-14 2015-04-23 Perstorp Ab Composition preventing necrotic enteritis in galloanserans
WO2015074767A1 (en) 2013-11-20 2015-05-28 Proviron Holding N.V. Animal feed comprising a combination of mono glycerides
WO2016093757A1 (en) * 2014-12-09 2016-06-16 Perstorp Ab Composition inhibiting gram-negative pathogens in galloanserans
WO2016159853A1 (en) * 2015-03-27 2016-10-06 Perstorp Ab Composition inhibiting gram-positive, pathogenic bacteria
WO2017082791A1 (en) * 2015-11-13 2017-05-18 Perstorp Ab Composition preventing bacterial inflammation in monogastric animals
US20190075824A1 (en) * 2016-06-01 2019-03-14 Kwan-Sik YUN Weight gain promoting feed additive, livestock feed composition and livestock breeding method
WO2019238892A1 (en) * 2018-06-15 2019-12-19 Taminco Bvba Treatment of poultry or pigs for reducing the feed conversion ratio or increasing their bodyweight gain
WO2020234357A1 (en) * 2019-05-21 2020-11-26 Société des Produits Nestlé S.A. Dietary butyrate and its uses
WO2020234348A1 (en) * 2019-05-21 2020-11-26 Société des Produits Nestlé S.A. Dietary butyrate
WO2020234354A1 (en) * 2019-05-21 2020-11-26 Société des Produits Nestlé S.A. Dietary butyrate and its uses
WO2020234345A1 (en) * 2019-05-21 2020-11-26 Société des Produits Nestlé S.A. Dietary butyrate
WO2020234351A1 (en) * 2019-05-21 2020-11-26 Société des Produits Nestlé S.A. Dietary butyrate and its uses
WO2020238406A1 (en) * 2019-05-30 2020-12-03 山东省新奥农牧发展有限公司 Feed composition and preparation method therefor and application thereof
WO2021110963A1 (en) * 2019-12-05 2021-06-10 Société des Produits Nestlé S.A. Dietary butyrate
WO2021191470A1 (en) * 2020-03-27 2021-09-30 Basf Se Composition comprising glycerides for the treatment of gastro-intestinal dysfunction and/or associated morbidities thereto
WO2022260568A1 (en) * 2021-06-09 2022-12-15 Perstorp Ab Mixed glycerol ester composition

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102090517A (en) * 2010-12-21 2011-06-15 南昌大学 Synthesis method of functional feed additive butyric acid mono-and di-glyceride
CN103082094B (en) * 2013-01-31 2014-10-29 武汉工业学院 Application of butyrin lactate as feed additive
CN103082095B (en) * 2013-01-31 2014-10-29 武汉工业学院 Application of triglyceryl lactate as feed acidifier
KR101719598B1 (en) * 2015-06-05 2017-03-24 윤관식 Oil composition for Livestock feed, Feed additives for promoting growth, Livestock feed composition and Method for Breeding Livestock using the same
US10669463B2 (en) * 2015-09-30 2020-06-02 Ndsu Research Foundation Bio-derived composition for dust control
US10336927B2 (en) * 2015-09-30 2019-07-02 Ndsu Research Foundation Bio-derived composition for dust control
CN106234770A (en) * 2016-07-28 2016-12-21 湖南晶天科技实业有限公司 A kind of feed additive, its application and a kind of feedstuff
CN108208341B (en) * 2017-12-29 2021-11-30 湖北浩华生物技术有限公司 Application of grease composition in preparation of pig and poultry feed additive, feed additive and feed
CN108126208A (en) * 2017-12-30 2018-06-08 天津赫莱恩特生物科技有限公司 A kind of preparation method of aerosol type suspending agent and its application on coccidial vaccine
US20210038554A1 (en) * 2018-06-01 2021-02-11 Societe Des Produits Nestle S.A. Dietary butyrate
EP3897178A1 (en) * 2018-12-18 2021-10-27 Société des Produits Nestlé S.A. Mixed triglyceriges
WO2020234355A1 (en) * 2019-05-21 2020-11-26 Société des Produits Nestlé S.A. Dietary butyrate
MX2021013513A (en) * 2019-05-21 2021-12-10 Nestle Sa Dietary butyrate and its uses.
EP4068988A1 (en) * 2019-12-05 2022-10-12 Société des Produits Nestlé S.A. Dietary butyrate and its uses
US20230102803A1 (en) * 2019-12-05 2023-03-30 Societe Des Produits Nestle S.A. Dietary butyrate and its uses

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3952107A (en) * 1973-04-04 1976-04-20 Nihon Nohyaku Kabushiki Kaisha Growth promotion using a certain glyceride mixture
EP0445692A2 (en) * 1990-03-06 1991-09-11 European Economic Community E.E.C. A method of producing monoglyceride
EP0519458A1 (en) * 1991-06-17 1992-12-23 Kao Corporation Feed additive for livestock and feed for livestock
WO1995013062A1 (en) * 1993-11-10 1995-05-18 Sloan-Kettering Institute For Cancer Research Butyric ester cyto-differentiating agents
US5565232A (en) * 1989-09-20 1996-10-15 Nabisco, Inc. Reduced calorie triglyceride mixtures
DE19718245C1 (en) * 1997-04-30 1998-07-30 Henkel Kgaa Synthetic tri:glyceride(s) useful as food additives
WO2001077271A2 (en) * 2000-04-06 2001-10-18 Conlinco, Inc. Conjugated linoleic acid compositions
EP1224870A1 (en) * 2001-01-23 2002-07-24 Xeris Use of tributyrin in animal feed and corresponding feed additive
EP1342419A1 (en) * 2002-03-08 2003-09-10 Fernando Cantini Lipid product based on monoglycerides and diglycerides of oleic acid, randomized triglycerides and glycerol, for animal nutrition
US20040062847A1 (en) * 2000-08-08 2004-04-01 Shin Koike Oil/fat composition

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4607052A (en) * 1983-04-15 1986-08-19 Roussel-Uclaf Triglycerides, dietetic and therapeutical applications and compositions containing them
JP3034678B2 (en) * 1991-06-17 2000-04-17 花王株式会社 Livestock feed additives and livestock feed
US6410078B1 (en) * 1995-04-28 2002-06-25 Loders-Croklaan B.V. Triglycerides, rich in polyunsaturated fatty acids
WO2000015043A1 (en) * 1998-09-11 2000-03-23 Danisco Cultor America, Inc. Reduced calorie plastic fat composition
JP3853552B2 (en) * 1999-12-17 2006-12-06 花王株式会社 Method for producing diglyceride
WO2003020782A2 (en) * 2001-08-29 2003-03-13 Ptc Organics, Inc. Transesterification using phase transfer catalysts
US20040086621A1 (en) * 2002-11-06 2004-05-06 Kraft Foods Holdings, Inc. Reduced calorie fat

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3952107A (en) * 1973-04-04 1976-04-20 Nihon Nohyaku Kabushiki Kaisha Growth promotion using a certain glyceride mixture
US5565232A (en) * 1989-09-20 1996-10-15 Nabisco, Inc. Reduced calorie triglyceride mixtures
EP0445692A2 (en) * 1990-03-06 1991-09-11 European Economic Community E.E.C. A method of producing monoglyceride
EP0519458A1 (en) * 1991-06-17 1992-12-23 Kao Corporation Feed additive for livestock and feed for livestock
WO1995013062A1 (en) * 1993-11-10 1995-05-18 Sloan-Kettering Institute For Cancer Research Butyric ester cyto-differentiating agents
DE19718245C1 (en) * 1997-04-30 1998-07-30 Henkel Kgaa Synthetic tri:glyceride(s) useful as food additives
WO2001077271A2 (en) * 2000-04-06 2001-10-18 Conlinco, Inc. Conjugated linoleic acid compositions
US20040062847A1 (en) * 2000-08-08 2004-04-01 Shin Koike Oil/fat composition
EP1224870A1 (en) * 2001-01-23 2002-07-24 Xeris Use of tributyrin in animal feed and corresponding feed additive
EP1342419A1 (en) * 2002-03-08 2003-09-10 Fernando Cantini Lipid product based on monoglycerides and diglycerides of oleic acid, randomized triglycerides and glycerol, for animal nutrition

Cited By (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8343753B2 (en) 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
WO2009115635A1 (en) * 2008-03-19 2009-09-24 Norel, S.A. Method for recyling by-products by means of the reconstitution of fats useful in animal feeding-stuffs
ES2325854A1 (en) * 2008-03-19 2009-09-21 Norel, S.A. Method for recyling by-products by means of the reconstitution of fats useful in animal feeding-stuffs
FR2933406A1 (en) * 2008-07-07 2010-01-08 Rhodia Poliamida E Especialidades Ltda PROCESS FOR OBTAINING GLYCERIDES BY ESTERIFYING ALCOHOL AND CARBOXYLIC ACID
WO2010003203A1 (en) * 2008-07-07 2010-01-14 Rhodia Poliamida E Especialidades Ltda Method of preparing glycerides by esterifying alcohol or a mixture of alcohols and carboxylic acids
WO2010060914A1 (en) * 2008-11-28 2010-06-03 Sila S.R.L. Process for the production of an n-butyric acid compound in micro encapsulated form, for animal or human consumption
US8603538B2 (en) 2008-11-28 2013-12-10 Sila S.R.L. Process for the production of an n-butyric acid compound in micro encapsulated form, for animal or human consumption
ITPD20080352A1 (en) * 2008-11-28 2010-05-29 Sila S R L PROCESS FOR THE PRODUCTION OF A COMPOUND OF N-BUTIRRIC ACID IN MICROCAPSULATED FORM, INTENDED FOR ANIMAL OR HUMAN POWER
EP2410871B1 (en) 2009-03-16 2015-11-04 Fernando Cantini Compositions containing c1 to c7 organic acid monoglycerides and glycerol,their preparation and use as antibacterials and anti-mould agents
ITFI20090050A1 (en) * 2009-03-16 2010-09-17 Fernando Cantini COMPOSITIONS CONTAINING MONOGLICERIDES OF ORGANIC ACIDS FROM C1 TO C7 AND GLYCEROL, THEIR PREPARATION AND USE AS ANTIBACTERIALS IN THE ZOOTECHNY.
WO2010106488A3 (en) * 2009-03-16 2010-11-11 Fernando Cantini Compositions containing c1 to c7 organic acid monoglycerides and glycerol, their preparation and use as antibacterials and anti-mould agents
EP2410871A2 (en) 2009-03-16 2012-02-01 Fernando Cantini Compositions containing c1 to c7 organic acid monoglycerides and glycerol,their preparation and use as antibacterials and anti-mould agents
US20120029075A1 (en) * 2009-03-16 2012-02-02 Fernando Cantini Compositions containing c1 to c7 organic acid monoglycerides and glycerol, their preparation and use as antibacterials and anti-mould agents
WO2015057121A1 (en) * 2013-10-14 2015-04-23 Perstorp Ab Composition preventing necrotic enteritis in galloanserans
EA031937B1 (en) * 2013-10-14 2019-03-29 Персторп АБ Composition preventing necrotic enteritis in galloanserans
US9877945B2 (en) 2013-10-14 2018-01-30 Perstorp Ab Composition preventing necrotic enteritis in galloanserans
WO2015074767A1 (en) 2013-11-20 2015-05-28 Proviron Holding N.V. Animal feed comprising a combination of mono glycerides
BE1021434B1 (en) * 2013-11-20 2015-11-20 Proviron Holding FEED FEED WITH A COMBINATION OF MONOGLYCERIDES.
CN105916385A (en) * 2013-11-20 2016-08-31 普罗维隆控股股份有限公司 Animal feed comprising a combination of mono glycerides
CN105916385B (en) * 2013-11-20 2019-12-27 普罗维隆控股股份有限公司 Animal feed comprising a combination of monoglycerides
US10398155B2 (en) 2013-11-20 2019-09-03 Proviron Holding N.V. Animal feed comprising a combination of mono glycerides
WO2016093757A1 (en) * 2014-12-09 2016-06-16 Perstorp Ab Composition inhibiting gram-negative pathogens in galloanserans
WO2016159853A1 (en) * 2015-03-27 2016-10-06 Perstorp Ab Composition inhibiting gram-positive, pathogenic bacteria
US10420745B2 (en) 2015-03-27 2019-09-24 Perstorp Ab Composition inhibiting gram-positive, pathogenic bacteria
WO2017082791A1 (en) * 2015-11-13 2017-05-18 Perstorp Ab Composition preventing bacterial inflammation in monogastric animals
US10576052B2 (en) * 2015-11-13 2020-03-03 Perstorp Ab Composition preventing bacterial inflammation in monogastric animals
US20190075824A1 (en) * 2016-06-01 2019-03-14 Kwan-Sik YUN Weight gain promoting feed additive, livestock feed composition and livestock breeding method
WO2019238892A1 (en) * 2018-06-15 2019-12-19 Taminco Bvba Treatment of poultry or pigs for reducing the feed conversion ratio or increasing their bodyweight gain
WO2020234348A1 (en) * 2019-05-21 2020-11-26 Société des Produits Nestlé S.A. Dietary butyrate
WO2020234357A1 (en) * 2019-05-21 2020-11-26 Société des Produits Nestlé S.A. Dietary butyrate and its uses
WO2020234354A1 (en) * 2019-05-21 2020-11-26 Société des Produits Nestlé S.A. Dietary butyrate and its uses
WO2020234345A1 (en) * 2019-05-21 2020-11-26 Société des Produits Nestlé S.A. Dietary butyrate
WO2020234351A1 (en) * 2019-05-21 2020-11-26 Société des Produits Nestlé S.A. Dietary butyrate and its uses
WO2020238406A1 (en) * 2019-05-30 2020-12-03 山东省新奥农牧发展有限公司 Feed composition and preparation method therefor and application thereof
WO2021110963A1 (en) * 2019-12-05 2021-06-10 Société des Produits Nestlé S.A. Dietary butyrate
WO2021191470A1 (en) * 2020-03-27 2021-09-30 Basf Se Composition comprising glycerides for the treatment of gastro-intestinal dysfunction and/or associated morbidities thereto
WO2022260568A1 (en) * 2021-06-09 2022-12-15 Perstorp Ab Mixed glycerol ester composition

Also Published As

Publication number Publication date
ITFI20050024A1 (en) 2006-08-15
EP1863356A1 (en) 2007-12-12
JP2008529521A (en) 2008-08-07
BRPI0520019A2 (en) 2009-04-14
CN101119648A (en) 2008-02-06
MX2007009582A (en) 2007-11-09
US20080268094A1 (en) 2008-10-30

Similar Documents

Publication Publication Date Title
US20080268094A1 (en) Mixtures of Fatty Acid Glycerides from C1 to C22 to Improve Zootechnical Performances and/or the Health of the Intestine of Animals
US6054147A (en) Method for increasing the incorporation efficiency of omega-3 highly unsaturated fatty acid in poultry meat
JP3949499B2 (en) Process for producing fatty acid calcium salts from oils with high glyceride content
JPS6398355A (en) Feed for animal
US3952107A (en) Growth promotion using a certain glyceride mixture
JP2009522241A (en) Method for producing calcium soap for animal feed
EP1164865B1 (en) Method for selectively altering body fat level, feed efficiency, or weight gain
US20090047378A1 (en) Non marine or non algal sourced omega 3 feed/food supplement and process for stabilizing, enhancing the conversion efficiency, and enrichment of omega 3 fatty acids in livestock/humans and products therefrom
JP2723243B2 (en) Animal feed with polyunsaturated fatty acids
CN109198187A (en) A kind of feed addictive and its preparation method and application for preventing and treating pig bloody flux
WO2015099817A1 (en) Method for improving feed efficiency and increasing growth rates in animals
RU2497377C1 (en) Chicken fodder
Herc et al. Effect of zeolite (Clinoptilolite) on chemical parameters of rabbit meat
JPH10215787A (en) Production method for oleic acid reinforced animal food and oleic acid reinforced animal food
JPS63237745A (en) Production of animal food with enriched content of alpha-linolenic acid based fatty acid
RU2736335C1 (en) Fodder additive for cattle in form of encapsulated fats and a method for production thereof
RU2742103C1 (en) Fodder additive production method for cattle
RU2734403C1 (en) Method for feeding broiler chickens
RU2714725C1 (en) Method for production of food eggs enriched with covalently bound iodine
RU2141228C1 (en) Method for producing feed or food product
KR100479018B1 (en) A process for producing a high L-carnitine-containing egg
RU2639327C2 (en) Fodder mixture for agricultural animals and poultry
WO2015053650A1 (en) Iodization method and iodine-containing product for use in feeding animals and birds
MXPA00001558A (en) A method for increasing incorporation efficiency of omega-3 highly unsaturated fatty acid in poultry meat

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
DPE2 Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101)
WWE Wipo information: entry into national phase

Ref document number: MX/a/2007/009582

Country of ref document: MX

Ref document number: 11883952

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: 2007554744

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 200580048090.0

Country of ref document: CN

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2005805811

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 4012/CHENP/2007

Country of ref document: IN

WWP Wipo information: published in national office

Ref document number: 2005805811

Country of ref document: EP

ENP Entry into the national phase

Ref document number: PI0520019

Country of ref document: BR

Kind code of ref document: A2