WO2006074568A1 - Dispositif de stockage automatique et armoire climatique pour articles de laboratoire - Google Patents

Dispositif de stockage automatique et armoire climatique pour articles de laboratoire Download PDF

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Publication number
WO2006074568A1
WO2006074568A1 PCT/CH2006/000028 CH2006000028W WO2006074568A1 WO 2006074568 A1 WO2006074568 A1 WO 2006074568A1 CH 2006000028 W CH2006000028 W CH 2006000028W WO 2006074568 A1 WO2006074568 A1 WO 2006074568A1
Authority
WO
WIPO (PCT)
Prior art keywords
storage
laboratory
receiving device
goods
shelves
Prior art date
Application number
PCT/CH2006/000028
Other languages
German (de)
English (en)
Inventor
Cosmas G. Malin
Original Assignee
Liconic Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liconic Ag filed Critical Liconic Ag
Priority to US11/814,067 priority Critical patent/US20080272674A1/en
Priority to EP06700201A priority patent/EP1836291A1/fr
Publication of WO2006074568A1 publication Critical patent/WO2006074568A1/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G1/00—Storing articles, individually or in orderly arrangement, in warehouses or magazines
    • B65G1/02—Storage devices
    • B65G1/04—Storage devices mechanical
    • B65G1/0407—Storage devices mechanical using stacker cranes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0401—Sample carriers, cuvettes or reaction vessels
    • G01N2035/0418—Plate elements with several rows of samples
    • G01N2035/042—Plate elements with several rows of samples moved independently, e.g. by fork manipulator
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0401—Sample carriers, cuvettes or reaction vessels
    • G01N2035/0418—Plate elements with several rows of samples
    • G01N2035/0425—Stacks, magazines or elevators for plates

Definitions

  • the present invention relates to an automatic storage device and a climate chamber for receiving laboratory supplies, in particular microtiter plates.
  • Microtiter plates In modern research, large quantities of samples must be tested, manipulated and stored. The storage of the samples is often done in so-called microtiter plates containing a variety of fine receiving wells for the samples. Microtiter plates usually have a standardized size with a base area of approx. 127.76 mm x 85.48 mm ( ⁇ 0.5 mm each) according to standard ANSI / ⁇ BS 1-2004, 1/8/2004, "for microplates - Footprint Dimensions", and a variety of devices have been provided to provide such plates or similar laboratory supplies, such as so-called laboratory "Flasks" store.
  • EP 1 332 987 describes a storage device with a storage lane, with two shelves arranged along the storage lane and a storage and retrieval unit that can be moved in the storage lane.
  • the storage and retrieval unit has a height-adjustable and extendable receiving device with which individual laboratory goods stored in the shelves can be picked up. A Such equipment is costly to manufacture and use.
  • the object is to improve the cost efficiency of such a device.
  • the receiving device is designed so that it is capable of simultaneously receiving a plurality of successively arranged laboratory goods and bring in an intermediate storage position. From there, a desired laboratory work can be taken from a separating device or. An additional laboratory item will be added to the other laboratory items. Then the receiving device can put the goods back on the shelf. This makes it possible to selectively access each and every one of the lab utilities with little effort.
  • Separation device may alternatively or additionally also be used to remove or place a lid resting on the laboratory utensil. to place such a lid on the laboratory utensil. This is particularly advantageous when using microtiter plates with lids.
  • the shelves have storage positions for receiving several laboratory goods in succession.
  • Each storage position has two runs parallel to each other and at the same height, on which opposite edge areas of the laboratory goods come directly to rest.
  • the receiving device can in insert the space between the supports and at the same time raise (or remove) all laboratory goods from the storage position from below. This solution makes it unnecessary to provide a drawer or the like for the laboratory goods.
  • the invention also relates to a climate cabinet with a corresponding storage device.
  • FIG. 1 the view of a climatic cabinet with a storage device according to the invention
  • FIG. 2 shows a schematic, horizontal section through the climatic cabinet according to FIG. 1 ,
  • Fig. 3 shows an embodiment of the storage device, wherein only four of the storage shafts are shown
  • Fig. 4 is a detail view of the storage and retrieval unit
  • FIG. 5 a part of a storage shaft
  • FIG. 6 is a view of a bearing shaft shown in a transparent manner
  • Fig. 7 is an enlarged view of a transparent bearing shaft
  • Fig. 8 shows a second embodiment of the storage and retrieval unit.
  • the climate cabinet according to FIG. 1 and 2 has a housing 1, in whose interior a control unit 3 with control and climatic generator and a storage device are housed.
  • the storage device has two shelves 4, which are arranged on both sides of a storage lane 5.
  • a storage and retrieval unit 6 In the storage lane 5 runs a storage and retrieval unit 6, with which automated access to all laboratory goods in the shelves 4 can be accessed.
  • a transfer station 7 is arranged. It serves for the temporary admission of individual laboratory goods at a transfer between the receiving device 17 of the storage and retrieval device 6 and an external transport system.
  • the transfer station 7 is z. B. from an attached to a wall 10 a of the air conditioning cabinet storage table for receiving the laboratory goods and is arranged at an automatic door 8 in the wall 10 a of the storage cabinet.
  • the size of the automatic door 8 corresponds approximately to the size of the laboratory goods to be handled so that climate losses when opening the door 8 remain small.
  • the automatic door 8 can also be arranged in the wall 10c opposite the wall 10a.
  • a further access door 11 is provided at the opposite end of the automatic door 8 of the storage cabinet.
  • This door which opens outwards, allows operators to gain access to the climatic chamber.
  • the door leads into an anteroom 13, which is formed between the shelves 4 and the shelves 4 opposite third wall 10c.
  • the control unit 3 is arranged.
  • FIG. 2 is the
  • Access door 11 arranged in the second wall 10b.
  • the door may also be arranged in a transverse to the storage lane 5 arranged wall, d. H . in the first wall 10a or the first opposing third wall 10c, advantageously in the extension of the storage lane 5, as shown in FIG. 2 dashed with reference numeral 11 ⁇ resp. 11 "is indicated. If the access door is arranged in position 11 "in the first wall 10a, then the automatic door 8 is advantageously arranged in the access door.
  • the structure of the bearing device is best shown in FIG. 3 and 4 can be seen. As mentioned, it has two shelves 4 along the storage lane 5.
  • the storage and retrieval unit 6 has a horizontal guide 15 in the form of a horizontal rail, which is arranged parallel to the rack aisle 5 in the ceiling region of the air conditioning cabinet.
  • a vertical guide 16 is guided in the form of a vertical rail.
  • the vertical guide 16 is disposed on the horizontal guide 15 and extends downwardly therefrom.
  • 16 may be provided at the lower end of the vertical guide still a second horizontal auxiliary guide.
  • a receiving device 17 is attached.
  • Receiving device 17 connected vertical drive 20 (hidden in FIG. 4 behind part 23), which drives a gear which engages in a rack 21 of the vertical guide 16.
  • a vertical column 23 is provided, which is connected at its lower end with a horizontal support arm 24.
  • an elongated table 25 is attached.
  • the table 25 can be pivoted relative to the support arm 24 about a vertical axis A. As shown in FIG. 2, the axis A lies approximately in the middle of the storage lane 5.
  • Zum Pivoting of the table 25 relative to the support arm 24 (and thus relative to the vertical guide 16) about the axis A is a pivot drive 27th
  • an elongated carrier 26 is arranged to be movable in the longitudinal direction of the table.
  • an extension drive 28 is provided on the table 25.
  • Table 25 and support 26 together form pivotable about axis A and extendable in an extension direction X receiving device 17.
  • On the column 23 is a further
  • Separation device 30 is arranged.
  • the separating device 30 can be moved vertically along the column 23 with a first separating drive 31. It has a gripper 32 for gripping the laboratory side.
  • the gripper 32 has at least two, preferably four downwardly projecting fingers 33a-33d, which are horizontally movable by means of a second separating drive 34 against each other.
  • the separating device 30 is located, viewed in the longitudinal direction of the storage lane 5, either in front of or behind the pivot axis A.
  • the receiving device 17 can be pivoted with the pivot drive 28 in three positions.
  • a transfer position which is shown in Fig. 3, it can be extended parallel to the storage lane 5.
  • the slightly extended carrier 26 is located below the separating device 30.
  • each of the laboratory goods 40 present on the carrier 26 can be brought into operative connection with the separating device 30.
  • the singulation device can be lowered vertically onto such a laboratory device 40, so that it can grip and lift the laboratory device 40 laterally with the gripper 32. Likewise, it can store a laboratory item in this way on a free space on the carrier 26.
  • the transfer position the
  • Receiving device 17 also labor and / or cover passed through the door 8 to the transfer station 7 or. from this record. From the transfer position, the
  • Fig. 4 shows the receiving device 17 in FIG.
  • the receiving device 17 can deliver laboratory goods in the manner described below to the shelves 4 or. of these record.
  • a second version of the receiving device 17 can deliver laboratory goods in the manner described below to the shelves 4 or. of these record.
  • Receiving device 17 is shown in FIG. 8 is shown. This differs from the first embodiment in that the separating device 30 is not stationary to the holding arm 24, but stationary to the table 25, d. H . it can be pivoted together with the table 25.
  • a column 35 with a vertical rack 35a is arranged on the table 25.
  • the gear of the vertically displaceable first separating drive 31 engages.
  • a support arm 36 is attached, which carries the gripper 32.
  • the gripper 32 is constructed substantially like the gripper of the first embodiment.
  • FIG. 8 The operation of the embodiment of FIG. 8 essentially corresponds to one according to FIG. 4, by the gripper 32 can be lowered from above onto the carrier 26 to there a laboratory or. to pick up or place a lid.
  • the structure of the shelves 4 is best shown in FIG. 3 can be seen.
  • Each shelf 4 has a frame 39 with, in the present embodiment, three shelves 41. At the top shelf 41 of the shelves, the horizontal guide 15 is attached.
  • On the two lower shelves 41 j edes shelves 4 are storage shafts 42, of which in FIG. 3 only four are shown.
  • Each bearing shaft 42 has two vertical side walls 43 which are connected at their upper and lower edges by horizontal plates 44.
  • FIG. 5 A part of a bearing shaft 42 is shown in Fig. 5. As can be seen, are provided on the side walls 43 at regular intervals inwardly projecting ribs, which form pads 45 for the male laboratory supplies 40. Each laboratory groove 40 is inserted into the bearing shaft 42 so that mutually opposite lower edge regions of the laboratory device are supported by a respective support or rib 45. Thus, each storage shaft 42 has a vertical row of storage positions 47 defined by the ribs 45. The storage shaft 42 is so deep that in each storage position 47 several laboratory goods can be placed one behind the other. The width and height of the storage positions 47 is adapted to the dimensions of the laboratory items to be taken in each case.
  • the storage shafts 42 are self-supporting units, and each storage shaft can, if necessary. with the laboratory items stored therein, as a whole the storage device or. taken from the climate cabinet. Between opposite editions resp.
  • a gap 46 is provided, which is wider than the extendable carrier 26. In the region of this gap 46, the underside of the laboratory device 40 is freely accessible. In order to grasp the laboratory goods, the receiving device or the carrier 26 can be introduced into the intermediate space 46.
  • Fig. 6 and 7 show a concrete embodiment of a bearing shaft 42. In particular, from FIG. 6 are three successively arranged laboratory goods 40 resp. Microplates can be seen on three successive storage locations on the pads resp. Ribs 45 rest. So that the laboratory goods 40 are kept defined in the longitudinal direction of the storage position 47 and can not slip, j eder storage space for receiving holding means 50, with which the j ehyroid Labororgut can be held in the longitudinal direction of the storage position 47.
  • the holding means 50 are in the embodiment of FIG. 6 and 7 are formed by elevations that protrude from the pads 45 against the top. The elevations are upwardly bent tongues of the supports 45 designed as sheets.
  • Separation device 30 from the laborgut takes 40 and raises this.
  • the receiving device 17 is pivoted back into the envelope position, extended into the shelf 4 and lowered slightly, so that the other laboratory goods are stored again in its storage position 47.
  • the now empty carrier 26 is withdrawn, pivoted into the transfer position and extended so far that its end portion is below the separating device 30.
  • the separating device lowers again and delivers the previously removed laboratory waste 40 to the carrier 26.
  • the receiving device 17 can be driven to the door 8.
  • the door 8 is opened and the carrier 26 is extended and lowered so that it deposits the laboratory work in the transfer position 7. In order to deposit a single laboratory item 40 at a predetermined position in the shelves 4, the reverse process is run through.
  • the receiving device 17 moves to the door 8, the carrier 26 is extended and raises the provided in the transfer position 7 Labororgut 40 at.
  • the carrier 26 is retracted.
  • the laboratory waste 40 is brought into the effective range of the separating device 30, which removes it from the carrier 26.
  • the receiving device 17 is moved to the desired storage position 47 and pivoted into the envelope position.
  • the carrier 26 extends, lifts the laboratory goods already in the storage position 47, pulls back and pivots into the transfer position. It is extended so far horizontally that a free space of the table below the separating device 30 comes to rest, whereupon the separating device 30 there touches the new laboratory. Then all laboratory goods are placed on the carrier 26 back into the shelf by the carrier 26 pivots back into the Umzzi ein, extends, lowers and the laboratory supplies 40 on the
  • the carrier 26 is withdrawn again.
  • several lab utensils 40 can also be handled on the table 25 at the same time.
  • the carrier 26 can take three successive laboratory utensils from a shelf position and together for
  • Transfer position 7 where the lab utensils are taken over or processed together. Conversely, several laboratories of the transfer position 7 can be brought together in one step to a storage location and stored there in succession.
  • Separation device 30 m is able to cache several Labororposition simultaneously. For example, it can record several laboratories, which are then taken over by the transfer position 7. For this purpose, the transfer position must be designed with means to take over the laboratory equipment directly from the separating device 30.
  • the device shown here can be adapted in many different ways to the respective requirements.
  • only one shelf may be provided, which is arranged along the storage lane 5. If different types of laboratory utensils are to be stored, then different storage shafts with correspondingly large storage positions can be provided.

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Warehouses Or Storage Devices (AREA)

Abstract

L'invention concerne un dispositif de stockage, destiné en particulier à une armoire climatique. Ce dispositif de stockage sert à stocker des articles de laboratoire, en particulier des plaques de microtitrage, dans des rayonnages (4). Il comprend un système de réception (17) servant à prélever ou ranger automatiquement les articles dans les rayonnages (4). Lesdits rayonnages (4) sont conçus de façon à pouvoir recevoir plusieurs articles disposés les uns derrière les autres, ce qui permet d'accroître fortement la capacité de stockage sans grande augmentation de l'encombrement de sorte que les coûts par article s'en trouvent réduits. Le système de réception (17) peut recevoir simultanément plusieurs articles disposés les uns derrière les autres et les placer dans une position de stockage intermédiaire. A partir de cette position, un article souhaité peut être prélevé par un système de prélèvement (30) ou un article supplémentaire peut être ajouté aux autres articles. Le système de réception peut ensuite replacer les articles dans le rayonnage. Le dispositif selon l'invention permet d'accéder de façon ciblée à chaque article individuel sans appareillage complexe.
PCT/CH2006/000028 2005-01-14 2006-01-12 Dispositif de stockage automatique et armoire climatique pour articles de laboratoire WO2006074568A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US11/814,067 US20080272674A1 (en) 2005-01-14 2006-01-12 Automatic Storing Device Climatic Chamber for Laboratory Objects
EP06700201A EP1836291A1 (fr) 2005-01-14 2006-01-12 Dispositif de stockage automatique et armoire climatique pour articles de laboratoire

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005001888.2 2005-01-12
DE102005001888A DE102005001888A1 (de) 2005-01-14 2005-01-14 Automatische Lagervorrichtung und Klimaschrank für Laborgüter

Publications (1)

Publication Number Publication Date
WO2006074568A1 true WO2006074568A1 (fr) 2006-07-20

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ID=36021003

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CH2006/000028 WO2006074568A1 (fr) 2005-01-14 2006-01-12 Dispositif de stockage automatique et armoire climatique pour articles de laboratoire

Country Status (4)

Country Link
US (1) US20080272674A1 (fr)
EP (1) EP1836291A1 (fr)
DE (1) DE102005001888A1 (fr)
WO (1) WO2006074568A1 (fr)

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US7861540B2 (en) 2008-01-25 2011-01-04 Hamilton Storage Technologies, Inc. Automated storage and retrieval system for storing biological or chemical samples at ultra-low temperatures
US8176747B2 (en) 2008-07-31 2012-05-15 Hamilton Storage Technologies, Inc. Tube picking mechanism for an automated, ultra-low temperature storage and retrieval system
US8857208B2 (en) 2007-03-20 2014-10-14 Liconic Ag Automated substance storage
US9163869B2 (en) 2010-09-09 2015-10-20 Hamilton Storage Technologies, Inc. Tube picking mechanisms with an ultra-low temperature or cryogenic picking compartment
US9255936B2 (en) 2010-09-10 2016-02-09 Hamilton Storage Technologies, Inc. Sample storage cassette for ultra-low or cryogenic temperatures
CN109602188A (zh) * 2017-08-24 2019-04-12 胡玥 一种具有可调式存储空间的快递柜

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DE102006034757B4 (de) * 2006-07-24 2009-09-10 Nobab Gmbh Vorrichtung und Verfahren zum automatisierten Ein- und Auslagern von Gegenständen
DE102006049160B3 (de) * 2006-10-18 2008-02-28 Bodensohn Präzision GmbH Lagervorrichtung für lose zuführbare Gegenstände
US9995525B2 (en) * 2009-01-19 2018-06-12 Liconic Ag Low-temperature automated storage for laboratory samples with automated access
EP2504107B1 (fr) * 2009-11-24 2019-11-06 Siemens Healthcare Diagnostics Inc. Système de gestion automatisé d'un stock de spécimens réfrigérés
DE202010012318U1 (de) 2010-09-06 2010-11-18 Cybio Ag Vorrichtung zur Lagerung und Bereitstellung von Objekten mit standardisierten Abmaßen
CH704128A1 (de) 2010-11-24 2012-05-31 Liconic Ag Lageranlage für tiefe Temperaturen und Lagerkassette für Laborobjekte.
CN102502149B (zh) * 2011-11-09 2013-07-17 江苏迅捷装具科技有限公司 一种抽屉式盒装物品储存配发装置及其配发补仓方法
EP2743614B1 (fr) 2012-12-12 2019-10-02 Liconic Ag Caisson de stockage pour objets de laboratoire
EP3415005B1 (fr) 2017-06-16 2022-08-03 Liconic Ag Banque de sang automatique
DE102019134394A1 (de) * 2019-12-13 2021-06-17 Hamilton Storage Gmbh Labor-Speicherschrank mit Rotationskörper in einer Transferschleuse
CN113058664B (zh) * 2021-03-23 2023-04-25 成都理工大学工程技术学院 一种实验室元器件储存装置

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US20080272674A1 (en) 2008-11-06
DE102005001888A1 (de) 2006-07-20

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