WO2006062909A3 - Methodes et compositions d'amelioration de l'acces vasculaire - Google Patents

Methodes et compositions d'amelioration de l'acces vasculaire Download PDF

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Publication number
WO2006062909A3
WO2006062909A3 PCT/US2005/043967 US2005043967W WO2006062909A3 WO 2006062909 A3 WO2006062909 A3 WO 2006062909A3 US 2005043967 W US2005043967 W US 2005043967W WO 2006062909 A3 WO2006062909 A3 WO 2006062909A3
Authority
WO
WIPO (PCT)
Prior art keywords
implantable material
cells
methods
present
functional
Prior art date
Application number
PCT/US2005/043967
Other languages
English (en)
Other versions
WO2006062909A2 (fr
Inventor
Helen Marie Nugent
Elazer Edelman
Anupam Dalal
Steve Bollinger
Scott Epperly
Original Assignee
Pervasis Therapeutics Inc
Helen Marie Nugent
Elazer Edelman
Anupam Dalal
Steve Bollinger
Scott Epperly
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pervasis Therapeutics Inc, Helen Marie Nugent, Elazer Edelman, Anupam Dalal, Steve Bollinger, Scott Epperly filed Critical Pervasis Therapeutics Inc
Priority to CA2589588A priority Critical patent/CA2589588C/fr
Priority to US11/792,350 priority patent/US20080119946A1/en
Priority to CN201210448869.3A priority patent/CN103055350B/zh
Priority to JP2007545539A priority patent/JP5674256B2/ja
Priority to JP2007545545A priority patent/JP2008522735A/ja
Priority to EP05848586A priority patent/EP1824526B1/fr
Priority to DE602005022481T priority patent/DE602005022481D1/de
Priority to AU2005314263A priority patent/AU2005314263B2/en
Priority to CN2005800421993A priority patent/CN101141988B/zh
Priority to AU2005314312A priority patent/AU2005314312B2/en
Priority to AT05853004T priority patent/ATE474608T1/de
Priority to CA2589597A priority patent/CA2589597C/fr
Priority to EP05853004A priority patent/EP1824529B1/fr
Priority to CN200580042372XA priority patent/CN101076360B/zh
Priority to PCT/US2005/043844 priority patent/WO2006062871A2/fr
Priority to US11/922,729 priority patent/US20090035346A1/en
Priority to SG2013075387A priority patent/SG195537A1/en
Priority to CA 2612751 priority patent/CA2612751A1/fr
Priority to JP2008518189A priority patent/JP5632580B2/ja
Priority to PCT/US2006/021755 priority patent/WO2007001744A2/fr
Priority to SG201002482-6A priority patent/SG161258A1/en
Priority to ES06772165.4T priority patent/ES2541684T3/es
Priority to AU2006262682A priority patent/AU2006262682B2/en
Priority to CA 2818182 priority patent/CA2818182C/fr
Priority to CN2010102362140A priority patent/CN101878757A/zh
Priority to CN2006800279776A priority patent/CN101257861B/zh
Priority to CN201210246619.1A priority patent/CN102743792B/zh
Priority to EP20060772165 priority patent/EP1901680B1/fr
Publication of WO2006062909A2 publication Critical patent/WO2006062909A2/fr
Publication of WO2006062909A3 publication Critical patent/WO2006062909A3/fr
Priority to IL183784A priority patent/IL183784A/en
Priority to IL183786A priority patent/IL183786A/en
Priority to IL188263A priority patent/IL188263A/en
Priority to HK08101925.0A priority patent/HK1112429A1/xx
Priority to US12/626,823 priority patent/US20100204783A1/en
Priority to US12/779,223 priority patent/US20100318016A1/en
Priority to IL209574A priority patent/IL209574A/en
Priority to AU2010249280A priority patent/AU2010249280B2/en
Priority to US13/040,650 priority patent/US20110229549A1/en
Priority to IL212764A priority patent/IL212764A0/en
Priority to JP2012110766A priority patent/JP2012148164A/ja
Priority to JP2012133043A priority patent/JP2012166084A/ja
Priority to IL220806A priority patent/IL220806A/en
Priority to JP2012256581A priority patent/JP2013039431A/ja
Priority to JP2014239567A priority patent/JP2015042682A/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3808—Endothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Prostheses (AREA)
  • External Artificial Organs (AREA)

Abstract

L'invention concerne une matière implantable comprenant une matrice biocompatible et des cellules qui, lorsqu'elles sont acheminées au niveau d'une structure d'accès vasculaire, peuvent généralement favoriser la fonctionnalité. Par exemple, la matière implantable de cette invention peut améliorer la maturation d'une fistule native artérioveineuse, ainsi que prolonger la fistule dans un état fonctionnel, mature approprié à la dialyse. En outre, la matière de cette invention peut favoriser la formation d'une greffe artérioveineuse fonctionnelle adéquate à la dialyse, ainsi que la formation d'une greffe de dérivation périphérique fonctionnelle. Ladite matière implantable peut être conçue sous une forme plane flexible ou sous forme d'une composition concentrée possédant des propriétés de mémoire de forme appropriées à l'implantation au niveau d'une greffe artérioveineuse ou anastomosée ou à l'implantation adjacente à la greffe ou située dans le voisinage de cette greffe. Selon les méthodes présentées, la matière implantable est fournie sur une surface externe d'un vaisseau sanguin. Certains modes de réalisation de forme plane flexible constituent une fente. Les matières des méthodes de cette invention comprennent des cellules, de préférence, des cellules endothéliales ou des cellules possédant un phénotype endothélial.
PCT/US2005/043967 2004-12-08 2005-12-06 Methodes et compositions d'amelioration de l'acces vasculaire WO2006062909A2 (fr)

Priority Applications (43)

Application Number Priority Date Filing Date Title
CA2589588A CA2589588C (fr) 2004-12-08 2005-12-06 Materiaux et methodes d'administration minimalement invasive d'une composition fluide contenant des cellules
US11/792,350 US20080119946A1 (en) 2004-12-08 2005-12-06 Methods And Compositions For Enhacing Vascular Access
CN201210448869.3A CN103055350B (zh) 2004-12-08 2005-12-06 含细胞的可流动组合物的最小侵入性给药的材料和方法
JP2007545539A JP5674256B2 (ja) 2004-12-08 2005-12-06 細胞含有流動性組成物の最小侵襲投与のための材料および方法
JP2007545545A JP2008522735A (ja) 2004-12-08 2005-12-06 血管アクセスを強化するための方法および組成物
EP05848586A EP1824526B1 (fr) 2004-12-08 2005-12-06 Materiaux et methodes d'administration minimalement invasive d'une composition fluide contenant des cellules
DE602005022481T DE602005022481D1 (de) 2004-12-08 2005-12-06 Zusammensetzungen und deren verwendung für besseren gefässzugang
AU2005314263A AU2005314263B2 (en) 2004-12-08 2005-12-06 Methods and compositions for enhancing vascular access
CN2005800421993A CN101141988B (zh) 2004-12-08 2005-12-06 增强血管通路的方法和组合物
AU2005314312A AU2005314312B2 (en) 2004-12-08 2005-12-06 Materials and methods for minimally-invasive administration of a cell-containing flowable composition
AT05853004T ATE474608T1 (de) 2004-12-08 2005-12-06 Zusammensetzungen und deren verwendung für besseren gefässzugang
CA2589597A CA2589597C (fr) 2004-12-08 2005-12-06 Methodes et compositions d'amelioration de l'acces vasculaire
EP05853004A EP1824529B1 (fr) 2004-12-08 2005-12-06 Compositions et leur utilisation dand l'amelioration de l'acces vasculaire
CN200580042372XA CN101076360B (zh) 2004-12-08 2005-12-06 含细胞的可流动组合物的最小侵入性给药的材料和方法
PCT/US2005/043844 WO2006062871A2 (fr) 2004-12-08 2005-12-06 Materiaux et methodes d'administration minimalement invasive d'une composition fluide contenant des cellules
ES06772165.4T ES2541684T3 (es) 2005-06-21 2006-06-05 Crioconservación de material biocompatible
CN2010102362140A CN101878757A (zh) 2005-06-21 2006-06-05 用于增强血管通路的方法和组合物
CA 2612751 CA2612751A1 (fr) 2005-06-21 2006-06-05 Composition de milieu de transport contenant un vegf pour le stockage decellules greffees dans une matrice biocompatible
JP2008518189A JP5632580B2 (ja) 2005-06-21 2006-06-05 脈管アクセスを改善するための方法および組成物
PCT/US2006/021755 WO2007001744A2 (fr) 2005-06-21 2006-06-05 Procedes et compositions permettant d'ameliorer l'acces vasculaire
SG201002482-6A SG161258A1 (en) 2005-06-21 2006-06-05 Methods and compositions for enhancing vascular access
US11/922,729 US20090035346A1 (en) 2005-06-21 2006-06-05 Methods and Compositions for Enhancing Vascular Access
AU2006262682A AU2006262682B2 (en) 2005-06-21 2006-06-05 Methods and compositions for enhancing vascular access
CA 2818182 CA2818182C (fr) 2005-06-21 2006-06-05 Procedes et compositions permettant d'ameliorer l'acces vasculaire
SG2013075387A SG195537A1 (en) 2005-06-21 2006-06-05 Methods and compositions for enhancing vascular access
CN2006800279776A CN101257861B (zh) 2005-06-21 2006-06-05 用于增强血管通路的方法和组合物
CN201210246619.1A CN102743792B (zh) 2005-06-21 2006-06-05 用于增强血管通路的方法和组合物
EP20060772165 EP1901680B1 (fr) 2005-06-21 2006-06-05 Cryopreservation de materiel biocompatible
IL183784A IL183784A (en) 2004-12-08 2007-06-07 Materials for minimally-invasive administration of a cell-containing flowable composition
IL183786A IL183786A (en) 2004-12-08 2007-06-07 Methods and compositions for enhancing vascular access
IL188263A IL188263A (en) 2005-06-21 2007-12-19 Compositions of Implant Material Storage and Methods for Implant Material Storage
HK08101925.0A HK1112429A1 (en) 2004-12-08 2008-02-21 Compositions and their use for enhancing vascular access
US12/626,823 US20100204783A1 (en) 2005-12-06 2009-11-27 Methods and compositions for enhancing vascular access
US12/779,223 US20100318016A1 (en) 2004-12-08 2010-05-13 Methods and Compositions for Enhancing Vascular Access
IL209574A IL209574A (en) 2004-12-08 2010-11-25 Materials and methods for providing flow-containing compounds with minimal penetration
AU2010249280A AU2010249280B2 (en) 2004-12-08 2010-12-10 Materials and methods for minimally-invasive administration of a cell-containing flowable composition
US13/040,650 US20110229549A1 (en) 2004-12-08 2011-03-04 Methods and Compositions for Enhancing Vascular Access
IL212764A IL212764A0 (en) 2004-12-08 2011-05-08 Methods and compositions for enhancing vascular access
JP2012110766A JP2012148164A (ja) 2004-12-08 2012-05-14 細胞含有流動性組成物の最小侵襲投与のための材料および方法
JP2012133043A JP2012166084A (ja) 2005-06-21 2012-06-12 脈管アクセスを改善するための方法および組成物
IL220806A IL220806A (en) 2005-06-21 2012-07-05 Methods and Compounds for Enhancing Vein Accessibility
JP2012256581A JP2013039431A (ja) 2004-12-08 2012-11-22 細胞含有流動性組成物の最小侵襲投与のための材料および方法
JP2014239567A JP2015042682A (ja) 2004-12-08 2014-11-27 細胞含有流動性組成物の最小侵襲投与のための材料および方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US63415504P 2004-12-08 2004-12-08
US60/634,155 2004-12-08
US66385905P 2005-03-21 2005-03-21
US60/663,859 2005-03-21
US68205405P 2005-05-18 2005-05-18
US60/682,054 2005-05-18
US4984405P 2005-12-06 2005-12-06

Related Child Applications (4)

Application Number Title Priority Date Filing Date
PCT/US2006/021755 Continuation WO2007001744A2 (fr) 2005-06-21 2006-06-05 Procedes et compositions permettant d'ameliorer l'acces vasculaire
US11/922,729 Continuation US20090035346A1 (en) 2005-06-21 2006-06-05 Methods and Compositions for Enhancing Vascular Access
US12/626,823 Continuation-In-Part US20100204783A1 (en) 2005-12-06 2009-11-27 Methods and compositions for enhancing vascular access
US12/779,223 Continuation US20100318016A1 (en) 2004-12-08 2010-05-13 Methods and Compositions for Enhancing Vascular Access

Publications (2)

Publication Number Publication Date
WO2006062909A2 WO2006062909A2 (fr) 2006-06-15
WO2006062909A3 true WO2006062909A3 (fr) 2006-08-31

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/043967 WO2006062909A2 (fr) 2004-12-08 2005-12-06 Methodes et compositions d'amelioration de l'acces vasculaire

Country Status (1)

Country Link
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Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE470701T1 (de) 2005-04-21 2010-06-15 Massachusetts Inst Technology Materialien und verfahren zur änderung einer immunreaktion auf exogene und endogene immunogene,einschliesslich genidentischer und nicht- genidentischer zellen, gewebe oder organe
SG161258A1 (en) 2005-06-21 2010-05-27 Pervasis Therapeutics Inc Methods and compositions for enhancing vascular access
WO2008057590A2 (fr) * 2006-11-07 2008-05-15 Pervasis Therapeutics, Inc. Méthodes et compositions de modulation de
AU2007317789B2 (en) * 2006-11-07 2011-02-10 Shire Regenerative Medicine, Inc. Materials and methods for treating and managing angiogenesis-mediated diseases
US10004508B2 (en) 2011-08-01 2018-06-26 Laminate Medical Technologies Ltd. Vessel shaping devices and methods

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820626A (en) * 1985-06-06 1989-04-11 Thomas Jefferson University Method of treating a synthetic or naturally occuring surface with microvascular endothelial cells, and the treated surface itself
WO2001062241A1 (fr) * 2000-02-23 2001-08-30 Smithkline Beecham Corporation Procede permettant de prevenir ou reduire les dysfonctionnements de l'acces vasculaire
US6328762B1 (en) * 1999-04-27 2001-12-11 Sulzer Biologics, Inc. Prosthetic grafts
US20020077694A1 (en) * 1999-06-30 2002-06-20 Pharmasonics, Inc. Methods and kits for the inhibition of hyperplasia in vascular fistulas and grafts
WO2002062335A2 (fr) * 2001-01-16 2002-08-15 Vascular Therapies, Llc Appareil et methodes de prevention ou de traitement en cas d'echec d'un acces vasculaire pour hemodialyse et en cas de rejet de greffons vasculaires
WO2004002549A1 (fr) * 2002-06-28 2004-01-08 Novartis Ag Utilisation de composes organiques

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820626A (en) * 1985-06-06 1989-04-11 Thomas Jefferson University Method of treating a synthetic or naturally occuring surface with microvascular endothelial cells, and the treated surface itself
US6328762B1 (en) * 1999-04-27 2001-12-11 Sulzer Biologics, Inc. Prosthetic grafts
US20020077694A1 (en) * 1999-06-30 2002-06-20 Pharmasonics, Inc. Methods and kits for the inhibition of hyperplasia in vascular fistulas and grafts
WO2001062241A1 (fr) * 2000-02-23 2001-08-30 Smithkline Beecham Corporation Procede permettant de prevenir ou reduire les dysfonctionnements de l'acces vasculaire
WO2002062335A2 (fr) * 2001-01-16 2002-08-15 Vascular Therapies, Llc Appareil et methodes de prevention ou de traitement en cas d'echec d'un acces vasculaire pour hemodialyse et en cas de rejet de greffons vasculaires
WO2004002549A1 (fr) * 2002-06-28 2004-01-08 Novartis Ag Utilisation de composes organiques

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HAZINEDAROGLU S M ET AL: "Immediate postimplant hemodialysis through a new ''self-sealing'' heparin-bonded polycarbonate/urethane graft", TRANSPLANTATION PROCEEDINGS, ORLANDO, FL, US, vol. 36, no. 9, November 2004 (2004-11-01), pages 2599 - 2602, XP004697046, ISSN: 0041-1345 *
HIRIGOYEN M B ET AL: "Periadventitial delivery of heparin in the prevention of microvenous thrombosis", JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, SAUNDERS, PHILADELPHIA, PA, US, vol. 54, no. 9, September 1996 (1996-09-01), pages 1097 - 1102, XP001097380, ISSN: 0278-2391 *

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