WO2006000158A8 - Utilisation de laetispicine pour la fabrication d'une composition pharmaceutique - Google Patents

Utilisation de laetispicine pour la fabrication d'une composition pharmaceutique

Info

Publication number
WO2006000158A8
WO2006000158A8 PCT/CN2005/000912 CN2005000912W WO2006000158A8 WO 2006000158 A8 WO2006000158 A8 WO 2006000158A8 CN 2005000912 W CN2005000912 W CN 2005000912W WO 2006000158 A8 WO2006000158 A8 WO 2006000158A8
Authority
WO
WIPO (PCT)
Prior art keywords
laetispicine
reuptake
pharmaceutical composition
monoamine neurotransmitter
manufacture
Prior art date
Application number
PCT/CN2005/000912
Other languages
English (en)
Chinese (zh)
Other versions
WO2006000158A1 (fr
Inventor
Sheng-Li Pan
Fu-Gang Qian
Jun Wang
Feng-Yan Sun
Jing Xie
Yi-Ci Shao
Original Assignee
Univ Fudan
Sheng-Li Pan
Fu-Gang Qian
Jun Wang
Feng-Yan Sun
Jing Xie
Yi-Ci Shao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Fudan, Sheng-Li Pan, Fu-Gang Qian, Jun Wang, Feng-Yan Sun, Jing Xie, Yi-Ci Shao filed Critical Univ Fudan
Publication of WO2006000158A1 publication Critical patent/WO2006000158A1/fr
Publication of WO2006000158A8 publication Critical patent/WO2006000158A8/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A61K31/5585—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention concerne l'utilisation de laetispicineur la fabrication d'une composition pharmaceutique destin inhiber la recapture du neurotransmetteur monoamine du système nrvu central, pour le traitement des maladies associées induitesparlarecapture du neurotransmetteur monoamine du système nerveu cenral
PCT/CN2005/000912 2004-06-25 2005-06-24 Utilisation de laetispicine pour la fabrication d'une composition pharmaceutique WO2006000158A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN200410025493.0 2004-06-25
CNB2004100254930A CN1332656C (zh) 2004-06-25 2004-06-25 化合物大叶蒟素在制备药物组合物中的应用

Publications (2)

Publication Number Publication Date
WO2006000158A1 WO2006000158A1 (fr) 2006-01-05
WO2006000158A8 true WO2006000158A8 (fr) 2006-02-09

Family

ID=34663697

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2005/000912 WO2006000158A1 (fr) 2004-06-25 2005-06-24 Utilisation de laetispicine pour la fabrication d'une composition pharmaceutique

Country Status (2)

Country Link
CN (1) CN1332656C (fr)
WO (1) WO2006000158A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101798297B (zh) * 2009-02-11 2013-02-27 中国科学院上海药物研究所 大叶蒟素的化学合成方法
CN102240281B (zh) * 2010-05-12 2014-05-14 天士力制药集团股份有限公司 5′-甲氧基-3′，4′-次甲二氧基桂皮酸异丁基酰胺在制备抗抑郁药物中的应用
CN102775394B (zh) * 2011-05-12 2016-03-09 天士力制药集团股份有限公司 一种酰胺类化合物及其制备方法和应用
CN104513172B (zh) * 2013-09-30 2018-02-02 天士力医药集团股份有限公司 含有三氟甲基的酰胺生物碱、制备方法及其药物用途
CN104940821A (zh) * 2015-06-28 2015-09-30 李先强 一种治疗余光恐惧症的中药

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1389462A (zh) * 2002-07-12 2003-01-08 复旦大学 大叶蒟素及其同系物，和在制备药物组合物中的应用

Also Published As

Publication number Publication date
WO2006000158A1 (fr) 2006-01-05
CN1593399A (zh) 2005-03-16
CN1332656C (zh) 2007-08-22

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