WO2005097186A3 - Endoprotheses vasculaires bioactives conçues pour le diabete type ii et leurs procedes d'utilisation - Google Patents

Endoprotheses vasculaires bioactives conçues pour le diabete type ii et leurs procedes d'utilisation Download PDF

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Publication number
WO2005097186A3
WO2005097186A3 PCT/US2005/011231 US2005011231W WO2005097186A3 WO 2005097186 A3 WO2005097186 A3 WO 2005097186A3 US 2005011231 W US2005011231 W US 2005011231W WO 2005097186 A3 WO2005097186 A3 WO 2005097186A3
Authority
WO
WIPO (PCT)
Prior art keywords
diabetics
type
vascular
bioligand
pecs
Prior art date
Application number
PCT/US2005/011231
Other languages
English (en)
Other versions
WO2005097186A2 (fr
Inventor
Kenneth W Carpenter
William G Turnell
Kristen M Defife
Kathryn A Grako
Original Assignee
Medivas Llc
Kenneth W Carpenter
William G Turnell
Kristen M Defife
Kathryn A Grako
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medivas Llc, Kenneth W Carpenter, William G Turnell, Kristen M Defife, Kathryn A Grako filed Critical Medivas Llc
Priority to EP05767563A priority Critical patent/EP1737379A4/fr
Priority to CN200580015085XA priority patent/CN1984620B/zh
Priority to JP2007507391A priority patent/JP2007532185A/ja
Priority to AU2005231458A priority patent/AU2005231458A1/en
Priority to CA002562018A priority patent/CA2562018A1/fr
Publication of WO2005097186A2 publication Critical patent/WO2005097186A2/fr
Publication of WO2005097186A3 publication Critical patent/WO2005097186A3/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/114—Nitric oxide, i.e. NO
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/25—Peptides having up to 20 amino acids in a defined sequence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A61L2300/256—Antibodies, e.g. immunoglobulins, vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A61L2300/604—Biodegradation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • A61L2300/608—Coatings having two or more layers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne une endoprothèse vasculaire ou un autre dispositif médical implantable susceptible d'être enveloppée d'un polymère biocompatible biodégradable auquel on fixe un ligand biologique qui capture spécifiquement des progéniteurs de cellules endothéliales (PEC) dans le sang en circulation afin de favoriser la formation endogène d'un endothélium sain dans le diabète type II. Dans un mode de réalisation, le ligand biologique est un peptide qui se lie spécifiquement à un récepteur des intégrines sur les PEC. L'invention concerne également des procédés permettant d'utiliser des endoprothèses vasculaires et d'autres dispositifs médicaux implantables pour favoriser la guérison vasculaire dans le diabète type II, par exemple à la suite d'une intervention mécanique.
PCT/US2005/011231 2004-04-05 2005-04-04 Endoprotheses vasculaires bioactives conçues pour le diabete type ii et leurs procedes d'utilisation WO2005097186A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP05767563A EP1737379A4 (fr) 2004-04-05 2005-04-04 Endoprotheses vasculaires bioactives concues pour le diabete type ii et leurs procedes d'utilisation
CN200580015085XA CN1984620B (zh) 2004-04-05 2005-04-04 用于ⅱ型糖尿病患者的生物活性支架
JP2007507391A JP2007532185A (ja) 2004-04-05 2005-04-04 Ｉｉ型糖尿病のための生理活性ステントおよびその使用方法
AU2005231458A AU2005231458A1 (en) 2004-04-05 2005-04-04 Bioactive stents for type II diabetics and methods for use thereof
CA002562018A CA2562018A1 (fr) 2004-04-05 2005-04-04 Endoprotheses vasculaires bioactives concues pour le diabete type ii et leurs procedes d'utilisation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55993704P 2004-04-05 2004-04-05
US60/559,937 2004-04-05

Publications (2)

Publication Number Publication Date
WO2005097186A2 WO2005097186A2 (fr) 2005-10-20
WO2005097186A3 true WO2005097186A3 (fr) 2006-09-14

Family

ID=35125623

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/011231 WO2005097186A2 (fr) 2004-04-05 2005-04-04 Endoprotheses vasculaires bioactives conçues pour le diabete type ii et leurs procedes d'utilisation

Country Status (6)

Country Link
EP (1) EP1737379A4 (fr)
JP (1) JP2007532185A (fr)
CN (1) CN1984620B (fr)
AU (1) AU2005231458A1 (fr)
CA (1) CA2562018A1 (fr)
WO (1) WO2005097186A2 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8652504B2 (en) 2005-09-22 2014-02-18 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
US9102830B2 (en) 2005-09-22 2015-08-11 Medivas, Llc Bis-(α-amino)-diol-diester-containing poly (ester amide) and poly (ester urethane) compositions and methods of use
US9517203B2 (en) 2000-08-30 2016-12-13 Mediv As, Llc Polymer particle delivery compositions and methods of use

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US20160287708A9 (en) * 2000-03-15 2016-10-06 Orbusneich Medical, Inc. Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device
US20060271168A1 (en) * 2002-10-30 2006-11-30 Klaus Kleine Degradable medical device
EP1699527A1 (fr) 2004-01-02 2006-09-13 Advanced Cardiovascular Systems, Inc. Dispositifs medicaux revetus de lipoproteine a haute densite
US8163269B2 (en) * 2004-04-05 2012-04-24 Carpenter Kenneth W Bioactive stents for type II diabetics and methods for use thereof
WO2007067744A2 (fr) * 2005-12-07 2007-06-14 Medivas, Llc Procédé destiné à assembler une composition d'administration polymère-agent biologique
EP2021141A4 (fr) * 2006-05-09 2013-07-03 Medivas Llc Polymères hydrosolubles biodégradables
US7572625B2 (en) * 2006-05-18 2009-08-11 Boston Scientific Scimed, Inc. Medical devices coated with drug carrier macromolecules
WO2008086490A2 (fr) * 2007-01-11 2008-07-17 Robert Lamar Bjork, Jr Endoprothèse coronaire à élution de médicaments multiples pour intervention coronarienne percutanée
JP2010533548A (ja) * 2007-07-17 2010-10-28 メディバス エルエルシー 生体吸収性エラストマー動脈支持装置および使用方法
US20090074831A1 (en) * 2007-09-18 2009-03-19 Robert Falotico LOCAL VASCULAR DELIVERY OF mTOR INHIBITORS IN COMBINATION WITH PEROXISOME PROLIFERATORS-ACTIVATED RECEPTOR STIMULATORS
DE102008027095A1 (de) * 2008-06-06 2009-12-17 Siemens Aktiengesellschaft Interventionsvorrichtung zur Sammlung von biologischem Material und Verfahren zu ihrer Herstellung
CN101879102B (zh) * 2009-05-07 2014-07-09 上海微创医疗器械（集团）有限公司 一种凹槽携载式涂层可降解型药物洗脱支架
EP2488225A1 (fr) * 2009-10-16 2012-08-22 DSM IP Assets B.V. Revêtements comprenant du polyesteramide contenant des motifs bis(alpha-aminodiesters de diols)
US9873765B2 (en) 2011-06-23 2018-01-23 Dsm Ip Assets, B.V. Biodegradable polyesteramide copolymers for drug delivery
US9963549B2 (en) 2011-06-23 2018-05-08 Dsm Ip Assets, B.V. Biodegradable polyesteramide copolymers for drug delivery
US20140220017A1 (en) 2011-09-23 2014-08-07 Universitat Stuttgart Serum half-life extension using igbd
US9220759B2 (en) 2012-02-23 2015-12-29 Abbott Cardiovascular Systems Inc. Treatment of diabetic patients with a drug eluting stent and adjunctive therapy
US9220584B2 (en) 2012-03-30 2015-12-29 Abbott Cardiovascular Systems Inc. Treatment of diabetic patients with a stent and locally administered adjunctive therapy
CA2892523A1 (fr) * 2012-12-20 2014-06-26 George Mihov Revetement comprenant des copolymeres de polyesteramide pour l'administration de medicament
EP3233067B1 (fr) 2014-12-18 2019-11-06 DSM IP Assets B.V. Système d'administration de médicament pour délivrer des médicaments sensibles à l'acide
EP4069327A1 (fr) * 2019-12-04 2022-10-12 Cortronik GmbH Fibres hybrides polymères gonflables pour un manchon d'une endoprothèse intraluminale

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9517203B2 (en) 2000-08-30 2016-12-13 Mediv As, Llc Polymer particle delivery compositions and methods of use
US8652504B2 (en) 2005-09-22 2014-02-18 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
US9102830B2 (en) 2005-09-22 2015-08-11 Medivas, Llc Bis-(α-amino)-diol-diester-containing poly (ester amide) and poly (ester urethane) compositions and methods of use

Also Published As

Publication number Publication date
CN1984620B (zh) 2011-03-30
WO2005097186A2 (fr) 2005-10-20
JP2007532185A (ja) 2007-11-15
CA2562018A1 (fr) 2005-10-20
EP1737379A4 (fr) 2011-08-17
CN1984620A (zh) 2007-06-20
AU2005231458A1 (en) 2005-10-20
EP1737379A2 (fr) 2007-01-03

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