WO2005040214A1 - Facteur viii viralement securise a faible teneur en multimeres superieurs - Google Patents
Facteur viii viralement securise a faible teneur en multimeres superieurs Download PDFInfo
- Publication number
- WO2005040214A1 WO2005040214A1 PCT/FR2004/002737 FR2004002737W WO2005040214A1 WO 2005040214 A1 WO2005040214 A1 WO 2005040214A1 FR 2004002737 W FR2004002737 W FR 2004002737W WO 2005040214 A1 WO2005040214 A1 WO 2005040214A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- factor
- fvw
- multimers
- log
- decamers
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0017—Filtration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
Abstract
Description
Claims
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT04805296T ATE452911T1 (de) | 2003-10-23 | 2004-10-25 | Virensicherer faktor viii mit niedrigem gehalt an höheren multimeren |
AU2004283931A AU2004283931B2 (en) | 2003-10-23 | 2004-10-25 | Virally-safe factor VIII with a low content of higher multimers |
JP2006536134A JP4872669B2 (ja) | 2003-10-23 | 2004-10-25 | 低含量の高次多量体を含むウイルスに関して安全な第viii因子 |
BRPI0415743-5A BRPI0415743A (pt) | 2003-10-23 | 2004-10-25 | fator viii viralmente segurizado com baixo teor em multìmeros superiores |
CA2543095A CA2543095C (fr) | 2003-10-23 | 2004-10-25 | Facteur viii viralement securise a faible teneur en multimeres superieurs |
EP04805296A EP1675872B1 (fr) | 2003-10-23 | 2004-10-25 | Facteur viii viralement securise a faible teneur en multimeres superieurs |
US10/576,794 US7932355B2 (en) | 2003-10-23 | 2004-10-25 | Virally-safe factor VIII with a low content of higher multimers |
DE602004024812T DE602004024812D1 (de) | 2003-10-23 | 2004-10-25 | Virensicherer faktor viii mit niedrigem gehalt an höheren multimeren |
IL175027A IL175027A (en) | 2003-10-23 | 2006-04-20 | METHOD FOR PREPARING VECTOR SOLUTION viii FREE OF VIRUSES |
IL228278A IL228278A (en) | 2003-10-23 | 2013-09-03 | Anti-coagulation factor viii, derived from plasma, is safe in terms of virus content |
IL228277A IL228277A (en) | 2003-10-23 | 2013-09-03 | METHOD FOR INVESTIGATING THE SAFETY SAFETY OF ANTICIPATIVES VIII IN VIEW CONTENTS |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0312398A FR2861395B1 (fr) | 2003-10-23 | 2003-10-23 | Facteur viii viralement securise a faible teneur en multimeres superieurs |
FR0312398 | 2003-10-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2005040214A1 true WO2005040214A1 (fr) | 2005-05-06 |
Family
ID=34400721
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/FR2004/002737 WO2005040214A1 (fr) | 2003-10-23 | 2004-10-25 | Facteur viii viralement securise a faible teneur en multimeres superieurs |
Country Status (12)
Country | Link |
---|---|
US (1) | US7932355B2 (fr) |
EP (3) | EP2805968A1 (fr) |
JP (2) | JP4872669B2 (fr) |
AT (1) | ATE452911T1 (fr) |
AU (1) | AU2004283931B2 (fr) |
BR (1) | BRPI0415743A (fr) |
CA (1) | CA2543095C (fr) |
DE (1) | DE602004024812D1 (fr) |
ES (1) | ES2335893T3 (fr) |
FR (1) | FR2861395B1 (fr) |
IL (3) | IL175027A (fr) |
WO (1) | WO2005040214A1 (fr) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2298096A1 (es) * | 2008-01-08 | 2008-05-01 | Grifols, S.A. | Procedimiento para la obtencion de un concetrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacion de los mismos. |
US8454833B2 (en) | 2007-12-28 | 2013-06-04 | Baxter International Inc. | Counter-pressure filtration of proteins |
CN104804078A (zh) * | 2015-05-05 | 2015-07-29 | 广东卫伦生物制药有限公司 | 人体血清凝血因子ⅷ中的病毒过滤方法 |
WO2019038350A1 (fr) | 2017-08-23 | 2019-02-28 | Csl Behring Gmbh | Procédé de filtration virale du facteur de von willebrand |
US11191837B2 (en) | 2007-12-28 | 2021-12-07 | Takeda Pharmaceutical Company Limited | Recombinant VWF formulations |
US11191813B2 (en) | 2007-12-28 | 2021-12-07 | Takeda Pharmaceutical Company Limited | Lyophilized recombinant VWF formulations |
US11197916B2 (en) | 2007-12-28 | 2021-12-14 | Takeda Pharmaceutical Company Limited | Lyophilized recombinant VWF formulations |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2920429B1 (fr) * | 2007-08-30 | 2012-10-05 | Lfb Biotechnologies | Procede de purification du facteur viii et du facteur von willebrand |
CN103608352A (zh) * | 2011-06-24 | 2014-02-26 | 旭化成医疗株式会社 | 蛋白制剂的制造方法 |
US20150080309A1 (en) | 2012-04-24 | 2015-03-19 | Nova Nordisk A/S | Compounds Suitable for Treatment of Haemophilia |
SG11202006593YA (en) * | 2018-02-19 | 2020-08-28 | Bayer Healthcare Llc | Modified filter membrane and method |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0860444A1 (fr) * | 1997-02-24 | 1998-08-26 | Stichting Centraal Laboratorium van de Bloedtransfusiedienst van het Nederlandse Rode Kruis (CLB) | Méthode pour l'élimination de virus des solutions protéiques |
WO1999031138A1 (fr) * | 1997-12-15 | 1999-06-24 | Laboratoire Français Du Fractionnement Et Des Biotechnologies | Procede de preparation par filtration d'une solution de facteur viii securisee viralement |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9500724D0 (sv) | 1994-06-23 | 1995-02-24 | Pharmacia Ab | Filtrering |
US5522991A (en) * | 1994-07-20 | 1996-06-04 | Millipore Investment Holdings Limited | Cellulosic ultrafiltration membrane |
PT1270595E (pt) | 2000-03-03 | 2008-09-16 | Kyowa Hakko Kogyo Kk | Anticorpo recombinante de genes e os seus fragmentos |
CA2785941C (fr) | 2000-10-06 | 2017-01-10 | Kyowa Hakko Kirin Co., Ltd. | Cellules produisant des compositions d'anticorps |
EP1443961B1 (fr) | 2001-10-25 | 2009-05-06 | Genentech, Inc. | Compositions de glycoproteine |
DE10211632A1 (de) | 2002-03-15 | 2003-10-09 | Aventis Behring Gmbh | Verfahren zur Abtrennung von Viren aus einer Proteinlösung durch Nanofiltration |
ES2298096B1 (es) * | 2008-01-08 | 2009-01-01 | Grifols, S.A. | Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacionde los mismos. |
-
2003
- 2003-10-23 FR FR0312398A patent/FR2861395B1/fr not_active Expired - Lifetime
-
2004
- 2004-10-25 JP JP2006536134A patent/JP4872669B2/ja not_active Expired - Fee Related
- 2004-10-25 EP EP14175614.8A patent/EP2805968A1/fr not_active Withdrawn
- 2004-10-25 EP EP09166591A patent/EP2108659A1/fr not_active Withdrawn
- 2004-10-25 US US10/576,794 patent/US7932355B2/en active Active
- 2004-10-25 CA CA2543095A patent/CA2543095C/fr not_active Expired - Fee Related
- 2004-10-25 WO PCT/FR2004/002737 patent/WO2005040214A1/fr active Application Filing
- 2004-10-25 BR BRPI0415743-5A patent/BRPI0415743A/pt not_active Application Discontinuation
- 2004-10-25 EP EP04805296A patent/EP1675872B1/fr not_active Revoked
- 2004-10-25 AT AT04805296T patent/ATE452911T1/de not_active IP Right Cessation
- 2004-10-25 ES ES04805296T patent/ES2335893T3/es active Active
- 2004-10-25 AU AU2004283931A patent/AU2004283931B2/en not_active Ceased
- 2004-10-25 DE DE602004024812T patent/DE602004024812D1/de active Active
-
2006
- 2006-04-20 IL IL175027A patent/IL175027A/en not_active IP Right Cessation
-
2011
- 2011-08-16 JP JP2011177898A patent/JP2011252016A/ja not_active Withdrawn
-
2013
- 2013-09-03 IL IL228277A patent/IL228277A/en not_active IP Right Cessation
- 2013-09-03 IL IL228278A patent/IL228278A/en not_active IP Right Cessation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0860444A1 (fr) * | 1997-02-24 | 1998-08-26 | Stichting Centraal Laboratorium van de Bloedtransfusiedienst van het Nederlandse Rode Kruis (CLB) | Méthode pour l'élimination de virus des solutions protéiques |
WO1999031138A1 (fr) * | 1997-12-15 | 1999-06-24 | Laboratoire Français Du Fractionnement Et Des Biotechnologies | Procede de preparation par filtration d'une solution de facteur viii securisee viralement |
Non-Patent Citations (2)
Title |
---|
METZNER H J ET AL: "CHARACTERIZATION OF FACTOR VIII/VON WILLEBRAND FACTOR CONCENTRATES USING A MODIFIED METHOD OF VON WILLEBRAND FACTOR MULTIMER ANALYSIS", HAEMOPHILIA, BLACKWELL SCIENCE, OXFORD, GB, vol. 4, no. SUPPL 3, 1998, pages 25 - 32, XP001156987, ISSN: 1351-8216 * |
WEINSTEIN R E: "IMMUNOAFFINITY PURIFICATION OF FACTOR VIII", ANNALS OF CLINICAL AND LABORATORY SCIENCE, INSTITUTE FOR CLINICAL SCIENCE, PHILADELPHIA, PA, US, vol. 19, no. 2, 1 March 1989 (1989-03-01), pages 84 - 91, XP002039904, ISSN: 0091-7370 * |
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8454833B2 (en) | 2007-12-28 | 2013-06-04 | Baxter International Inc. | Counter-pressure filtration of proteins |
JP2014166989A (ja) * | 2007-12-28 | 2014-09-11 | Baxter Internatl Inc | タンパク質の逆圧濾過 |
AU2008345218B2 (en) * | 2007-12-28 | 2015-02-19 | Takeda Pharmaceutical Company Limited | Counter-pressure filtration of proteins |
US11191837B2 (en) | 2007-12-28 | 2021-12-07 | Takeda Pharmaceutical Company Limited | Recombinant VWF formulations |
US11191813B2 (en) | 2007-12-28 | 2021-12-07 | Takeda Pharmaceutical Company Limited | Lyophilized recombinant VWF formulations |
US11197916B2 (en) | 2007-12-28 | 2021-12-14 | Takeda Pharmaceutical Company Limited | Lyophilized recombinant VWF formulations |
ES2298096A1 (es) * | 2008-01-08 | 2008-05-01 | Grifols, S.A. | Procedimiento para la obtencion de un concetrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacion de los mismos. |
EP2078730A1 (fr) | 2008-01-08 | 2009-07-15 | Grifols, S.A. | Procédé pour obtenir un concentré de facteur Von Willebrand ou complexe de facteur VIII/facteur Von Willebrand et utilisation associée |
US8354505B2 (en) | 2008-01-08 | 2013-01-15 | Grifols, S.A. | Process for obtaining a concentrate of Von Willebrand factor or a complex of factor VII/Von Willebrand factor and use of the same |
CN104804078A (zh) * | 2015-05-05 | 2015-07-29 | 广东卫伦生物制药有限公司 | 人体血清凝血因子ⅷ中的病毒过滤方法 |
CN104804078B (zh) * | 2015-05-05 | 2019-01-04 | 广东卫伦生物制药有限公司 | 人体血清凝血因子ⅷ中的病毒过滤方法 |
WO2019038350A1 (fr) | 2017-08-23 | 2019-02-28 | Csl Behring Gmbh | Procédé de filtration virale du facteur de von willebrand |
Also Published As
Publication number | Publication date |
---|---|
AU2004283931A1 (en) | 2005-05-06 |
CA2543095A1 (fr) | 2005-05-06 |
ES2335893T3 (es) | 2010-04-06 |
AU2004283931B2 (en) | 2010-08-26 |
FR2861395B1 (fr) | 2006-02-17 |
IL175027A (en) | 2013-10-31 |
IL228277A (en) | 2015-07-30 |
BRPI0415743A (pt) | 2006-12-19 |
ATE452911T1 (de) | 2010-01-15 |
EP1675872A1 (fr) | 2006-07-05 |
US7932355B2 (en) | 2011-04-26 |
CA2543095C (fr) | 2017-07-11 |
FR2861395A1 (fr) | 2005-04-29 |
US20070275880A1 (en) | 2007-11-29 |
EP2108659A1 (fr) | 2009-10-14 |
EP1675872B1 (fr) | 2009-12-23 |
JP2011252016A (ja) | 2011-12-15 |
JP2007535487A (ja) | 2007-12-06 |
DE602004024812D1 (de) | 2010-02-04 |
JP4872669B2 (ja) | 2012-02-08 |
IL175027A0 (en) | 2006-08-20 |
IL228278A (en) | 2015-07-30 |
EP2805968A1 (fr) | 2014-11-26 |
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