WO2005004926A8 - 樹状細胞浸潤能活性化組成物及び免疫賦活剤 - Google Patents

樹状細胞浸潤能活性化組成物及び免疫賦活剤

Info

Publication number
WO2005004926A8
WO2005004926A8 PCT/JP2003/008720 JP0308720W WO2005004926A8 WO 2005004926 A8 WO2005004926 A8 WO 2005004926A8 JP 0308720 W JP0308720 W JP 0308720W WO 2005004926 A8 WO2005004926 A8 WO 2005004926A8
Authority
WO
WIPO (PCT)
Prior art keywords
infiltrativity
dendritic cell
activating
activating composition
immune activator
Prior art date
Application number
PCT/JP2003/008720
Other languages
English (en)
French (fr)
Other versions
WO2005004926A1 (ja
Inventor
Masanobu Kobayashi
Original Assignee
Oncorex Inc
Masanobu Kobayashi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncorex Inc, Masanobu Kobayashi filed Critical Oncorex Inc
Priority to US10/563,612 priority Critical patent/US20060275268A1/en
Priority to JP2005503841A priority patent/JPWO2005004926A1/ja
Priority to CA002531636A priority patent/CA2531636A1/en
Priority to EP03817419A priority patent/EP1647256A4/en
Priority to PCT/JP2003/008720 priority patent/WO2005004926A1/ja
Priority to AU2003248255A priority patent/AU2003248255A1/en
Publication of WO2005004926A1 publication Critical patent/WO2005004926A1/ja
Publication of WO2005004926A8 publication Critical patent/WO2005004926A8/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

本発明の樹状細胞浸潤能活性化組成物はレチノイドを含有する。レチノイドは、樹状細胞が浸潤能を発揮するために必要なＭＭＰ−９の産生を増大し、それにより、樹状細胞の浸潤能を活性化する。従って、免疫賦活化作用を有し、動物の感染症、癌の予防・治療に用いることができる。
PCT/JP2003/008720 2003-07-09 2003-07-09 樹状細胞浸潤能活性化組成物及び免疫賦活剤 WO2005004926A1 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
US10/563,612 US20060275268A1 (en) 2003-07-09 2003-07-09 Compositions for activating the infiltration activity of dendritic cells, and immunopotentiating agents
JP2005503841A JPWO2005004926A1 (ja) 2003-07-09 2003-07-09 樹状細胞浸潤能活性化組成物及び免疫賦活剤
CA002531636A CA2531636A1 (en) 2003-07-09 2003-07-09 Compositions for activating the infiltration activity of dendritic cells and immunopotentiating agents
EP03817419A EP1647256A4 (en) 2003-07-09 2003-07-09 COMPOSITION FOR ACTIVATING THE INFILABILITY OF DENDRITIC CELLS AND IMMUNE ACTIVATOR
PCT/JP2003/008720 WO2005004926A1 (ja) 2003-07-09 2003-07-09 樹状細胞浸潤能活性化組成物及び免疫賦活剤
AU2003248255A AU2003248255A1 (en) 2003-07-09 2003-07-09 Dendritic cell infiltrativity activating composition and immune activator

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2003/008720 WO2005004926A1 (ja) 2003-07-09 2003-07-09 樹状細胞浸潤能活性化組成物及び免疫賦活剤

Publications (2)

Publication Number Publication Date
WO2005004926A1 WO2005004926A1 (ja) 2005-01-20
WO2005004926A8 true WO2005004926A8 (ja) 2005-06-30

Family

ID=34044597

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2003/008720 WO2005004926A1 (ja) 2003-07-09 2003-07-09 樹状細胞浸潤能活性化組成物及び免疫賦活剤

Country Status (6)

Country Link
US (1) US20060275268A1 (ja)
EP (1) EP1647256A4 (ja)
JP (1) JPWO2005004926A1 (ja)
AU (1) AU2003248255A1 (ja)
CA (1) CA2531636A1 (ja)
WO (1) WO2005004926A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6966665B2 (en) 2003-06-27 2005-11-22 S. C. Johnson & Son, Inc. Flameless candle with air intake chamber and air outflow chamber
AU2006321890A1 (en) * 2005-12-08 2007-06-14 University Of Louisville Research Foundation, Inc. Methods and compositions for expanding T regulatory cells

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05163160A (ja) * 1991-12-13 1993-06-29 Snow Brand Milk Prod Co Ltd 免疫低下に伴う感染症の予防及び治療用栄養剤
JPH06192073A (ja) * 1992-12-24 1994-07-12 Eisai Co Ltd 細胞分化誘導剤
WO1998006823A2 (en) * 1996-08-14 1998-02-19 Nexell Therapeutics Inc. Cytokine-free culture of dendritic cells
AU4423799A (en) * 1998-06-04 1999-12-20 Cornell Research Foundation Inc. Methods and agents for modulating the immune response and inflammation involvingmonocyte and dendritic cell membrane proteins

Also Published As

Publication number Publication date
CA2531636A1 (en) 2005-01-20
US20060275268A1 (en) 2006-12-07
WO2005004926A1 (ja) 2005-01-20
EP1647256A1 (en) 2006-04-19
AU2003248255A8 (en) 2005-01-28
EP1647256A4 (en) 2007-10-31
JPWO2005004926A1 (ja) 2006-08-24
AU2003248255A1 (en) 2005-01-28

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