WO2005003762A3 - Diagnostics and therapeutics for diseases associated with sensory neuron-specific g protein-coupled receptor 2 (snsr2) - Google Patents

Diagnostics and therapeutics for diseases associated with sensory neuron-specific g protein-coupled receptor 2 (snsr2) Download PDF

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Publication number
WO2005003762A3
WO2005003762A3 PCT/EP2004/006059 EP2004006059W WO2005003762A3 WO 2005003762 A3 WO2005003762 A3 WO 2005003762A3 EP 2004006059 W EP2004006059 W EP 2004006059W WO 2005003762 A3 WO2005003762 A3 WO 2005003762A3
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WO
WIPO (PCT)
Prior art keywords
disorders
snsr2
therapeutics
diagnostics
protein
Prior art date
Application number
PCT/EP2004/006059
Other languages
French (fr)
Other versions
WO2005003762A2 (en
Inventor
Stefan Golz
Ulf Brueggemeier
Holger Summer
Original Assignee
Bayer Healthcare Ag
Stefan Golz
Ulf Brueggemeier
Holger Summer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag, Stefan Golz, Ulf Brueggemeier, Holger Summer filed Critical Bayer Healthcare Ag
Publication of WO2005003762A2 publication Critical patent/WO2005003762A2/en
Publication of WO2005003762A3 publication Critical patent/WO2005003762A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention provides a human SNSR2 which is associated with the cardiovascular disorders, gastrointestinal and liver diseases, cancer disorders, inflammatory diseases, hematological disorders, respiratory diseases, neurological disorders and urological disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, gastrointestinal and liver diseases, cancer disorders, inflammatory diseases, hematological disorders, respiratory diseases, neurological disorders and urological disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of SNSR2 as well as pharmaceutical compositions comprising such compounds.
PCT/EP2004/006059 2003-06-17 2004-06-04 Diagnostics and therapeutics for diseases associated with sensory neuron-specific g protein-coupled receptor 2 (snsr2) WO2005003762A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03013716.0 2003-06-17
EP03013716 2003-06-17

Publications (2)

Publication Number Publication Date
WO2005003762A2 WO2005003762A2 (en) 2005-01-13
WO2005003762A3 true WO2005003762A3 (en) 2005-06-16

Family

ID=33560744

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/006059 WO2005003762A2 (en) 2003-06-17 2004-06-04 Diagnostics and therapeutics for diseases associated with sensory neuron-specific g protein-coupled receptor 2 (snsr2)

Country Status (1)

Country Link
WO (1) WO2005003762A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI580694B (en) 2007-11-30 2017-05-01 建南德克公司 Anti-vegf antibodies
MX2011004306A (en) 2008-10-22 2011-07-28 Genentech Inc Modulation of axon degeneration.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999032519A1 (en) * 1997-12-22 1999-07-01 Astrazeneca Canada Inc. Novel g protein-coupled receptor
WO2002033416A1 (en) * 2000-10-17 2002-04-25 Astrazeneca Ab Assays

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999032519A1 (en) * 1997-12-22 1999-07-01 Astrazeneca Canada Inc. Novel g protein-coupled receptor
WO2002033416A1 (en) * 2000-10-17 2002-04-25 Astrazeneca Ab Assays

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LEMBO P M C ET AL: "Proenkephalin A gene products activate a new family of sensory neuron-specific GPCRs", NATURE NEUROSCIENCE, NATURE AMERICA, INC, US, vol. 5, no. 3, March 2002 (2002-03-01), pages 201 - 209, XP002264104, ISSN: 1097-6256 *

Also Published As

Publication number Publication date
WO2005003762A2 (en) 2005-01-13

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