WO2004106941A3 - Especes de polypeptides secretes associees a des troubles cardio-vasculaires - Google Patents

Especes de polypeptides secretes associees a des troubles cardio-vasculaires Download PDF

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Publication number
WO2004106941A3
WO2004106941A3 PCT/EP2004/005786 EP2004005786W WO2004106941A3 WO 2004106941 A3 WO2004106941 A3 WO 2004106941A3 EP 2004005786 W EP2004005786 W EP 2004005786W WO 2004106941 A3 WO2004106941 A3 WO 2004106941A3
Authority
WO
WIPO (PCT)
Prior art keywords
cardiovascular disorders
secreted polypeptide
species associated
polypeptide species
polypeptides
Prior art date
Application number
PCT/EP2004/005786
Other languages
English (en)
Other versions
WO2004106941A2 (fr
Inventor
Lydie Bougueleret
Original Assignee
Genova Ltd
Novartis Pharma Gmbh
Lydie Bougueleret
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genova Ltd, Novartis Pharma Gmbh, Lydie Bougueleret filed Critical Genova Ltd
Priority to EP04735211A priority Critical patent/EP1634086A2/fr
Priority to JP2006529944A priority patent/JP2007513063A/ja
Publication of WO2004106941A2 publication Critical patent/WO2004106941A2/fr
Publication of WO2004106941A3 publication Critical patent/WO2004106941A3/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des polypeptides humains sécrétés circulant à un taux accru dans le plasma de patients souffrant de troubles cardio-vasculaires. L'invention concerne également des procédés d'utilisation de compositions renfermant les polypeptides, des polynucléotides codant ceux-ci et des anticorps spécifiques de ces polypeptides, aux fins de diagnostic, de pronostic et de développement de médicaments.
PCT/EP2004/005786 2003-05-30 2004-05-28 Especes de polypeptides secretes associees a des troubles cardio-vasculaires WO2004106941A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP04735211A EP1634086A2 (fr) 2003-05-30 2004-05-28 Especes de polypeptides secretes associees a des troubles cardio-vasculaires
JP2006529944A JP2007513063A (ja) 2003-05-30 2004-05-28 心臓血管障害に関連する分泌ポリペプチド種

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US47508303P 2003-05-30 2003-05-30
US47508203P 2003-05-30 2003-05-30
US47512103P 2003-05-30 2003-05-30
US60/475,082 2003-05-30
US60/475,083 2003-05-30
US60/475,121 2003-05-30
US48410203P 2003-06-30 2003-06-30
US60/484,102 2003-06-30

Publications (2)

Publication Number Publication Date
WO2004106941A2 WO2004106941A2 (fr) 2004-12-09
WO2004106941A3 true WO2004106941A3 (fr) 2005-05-26

Family

ID=33494283

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/005786 WO2004106941A2 (fr) 2003-05-30 2004-05-28 Especes de polypeptides secretes associees a des troubles cardio-vasculaires

Country Status (3)

Country Link
EP (1) EP1634086A2 (fr)
JP (1) JP2007513063A (fr)
WO (1) WO2004106941A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6835545B2 (en) 2000-05-08 2004-12-28 President And Fellows Of Harvard College Methods, products and treatments for diabetes
US7439330B2 (en) 2000-05-08 2008-10-21 President And Fellows Of Harvard College Anti-glycated CD59 antibodies and uses thereof
FI118265B (fi) * 2004-01-15 2007-09-14 Jurilab Ltd Oy Menetelmä akuutin sydäninfarktin ja sepelvaltimotaudin riskin havaitsemiseksi
US7833725B2 (en) 2005-01-06 2010-11-16 President And Fellows Of Harvard College Mass spectrometric methods and products
US8238515B2 (en) * 2007-08-16 2012-08-07 Caldera Pharmaceuticals, Inc. Well plate
JP5318874B2 (ja) * 2007-09-10 2013-10-16 ジーイー・ヘルスケア・リミテッド 放射性フッ素化方法
US9068006B2 (en) 2010-08-25 2015-06-30 President And Fellows Of Harvard College Glycated CD59 peptides, their preparation, and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641497A (en) * 1992-05-22 1997-06-24 Children's Hospital Of Philadelphia Gastrointestinal defensins, cDNA sequences and method for the production and use thereof
WO2001030354A1 (fr) * 1999-10-26 2001-05-03 Thomas Jefferson University Regulation d'apob permettant le diagnostic, le traitement et le criblage de medicaments pour des troubles ou des syndromes cardio-vasculaires et metaboliques

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641497A (en) * 1992-05-22 1997-06-24 Children's Hospital Of Philadelphia Gastrointestinal defensins, cDNA sequences and method for the production and use thereof
WO2001030354A1 (fr) * 1999-10-26 2001-05-03 Thomas Jefferson University Regulation d'apob permettant le diagnostic, le traitement et le criblage de medicaments pour des troubles ou des syndromes cardio-vasculaires et metaboliques

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HIGAZI ABD AL-ROOF ET AL: "Defensin stimulates the binding of lipoprotein (a) to human vascular endothelial and smooth muscle cells", BLOOD, vol. 89, no. 12, 1997, pages 4290 - 4298, XP002299296, ISSN: 0006-4971 *
TANG YI-QUAN ET AL: "Isolation, characterization, cDNA cloning, and antimicrobial properties of two distinct subfamilies of alpha-defensins from rhesus macaque leukocytes", INFECTION AND IMMUNITY, vol. 67, no. 11, November 1999 (1999-11-01), pages 6139 - 6144, XP002299297, ISSN: 0019-9567 *

Also Published As

Publication number Publication date
JP2007513063A (ja) 2007-05-24
EP1634086A2 (fr) 2006-03-15
WO2004106941A2 (fr) 2004-12-09

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