WO2004100927A3 - Injizierbare depots aus liposomalen aggregaten zum wirkstoffdelivery - Google Patents

Injizierbare depots aus liposomalen aggregaten zum wirkstoffdelivery Download PDF

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Publication number
WO2004100927A3
WO2004100927A3 PCT/DE2004/001020 DE2004001020W WO2004100927A3 WO 2004100927 A3 WO2004100927 A3 WO 2004100927A3 DE 2004001020 W DE2004001020 W DE 2004001020W WO 2004100927 A3 WO2004100927 A3 WO 2004100927A3
Authority
WO
WIPO (PCT)
Prior art keywords
active substances
delivery
injectable depots
liposomal
aggregates
Prior art date
Application number
PCT/DE2004/001020
Other languages
English (en)
French (fr)
Other versions
WO2004100927A2 (de
WO2004100927A8 (de
Inventor
Steffen Panzner
Silke Lutz
Original Assignee
Novosom Ag
Steffen Panzner
Silke Lutz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2003122123 external-priority patent/DE10322123A1/de
Priority claimed from DE102004017996A external-priority patent/DE102004017996A1/de
Application filed by Novosom Ag, Steffen Panzner, Silke Lutz filed Critical Novosom Ag
Priority to US10/556,703 priority Critical patent/US20070053918A1/en
Priority to EP04731879A priority patent/EP1624857A2/de
Priority to CA002525468A priority patent/CA2525468A1/en
Publication of WO2004100927A2 publication Critical patent/WO2004100927A2/de
Publication of WO2004100927A8 publication Critical patent/WO2004100927A8/de
Publication of WO2004100927A3 publication Critical patent/WO2004100927A3/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Die Erfindung betrifft Formulierungen aus Liposomen und Polymeren zur Herstellung eines injizierbaren Depots von Wirkstoffen, das eine langanhaltende Freisetzung und Wirkung in einem Säugetierorganismus aufweist.
PCT/DE2004/001020 2003-05-12 2004-05-10 Injizierbare depots aus liposomalen aggregaten zum wirkstoffdelivery WO2004100927A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US10/556,703 US20070053918A1 (en) 2003-05-12 2004-05-10 Injectable depots consisting of liposomal aggregates for the delivery of active substances
EP04731879A EP1624857A2 (de) 2003-05-12 2004-05-10 Injizierbare depots aus liposomalen aggregaten zur wirkstoffverabreichung
CA002525468A CA2525468A1 (en) 2003-05-12 2004-05-10 Injectable depots consisting of liposomal aggregates for the delivery of active substances

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10322123.9 2003-05-12
DE2003122123 DE10322123A1 (de) 2003-05-12 2003-05-12 Injizierbare Depots aus Liposomen und Polymeren zum Peptid- & Proteindelivery
DE102004017996A DE102004017996A1 (de) 2004-04-10 2004-04-10 Injizierbare Depots aus liposomalen Aggregaten zum Wirkstoffdelivery
DE102004017996.4 2004-04-10

Publications (3)

Publication Number Publication Date
WO2004100927A2 WO2004100927A2 (de) 2004-11-25
WO2004100927A8 WO2004100927A8 (de) 2005-03-24
WO2004100927A3 true WO2004100927A3 (de) 2005-07-21

Family

ID=33453862

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2004/001020 WO2004100927A2 (de) 2003-05-12 2004-05-10 Injizierbare depots aus liposomalen aggregaten zum wirkstoffdelivery

Country Status (4)

Country Link
US (1) US20070053918A1 (de)
EP (1) EP1624857A2 (de)
CA (1) CA2525468A1 (de)
WO (1) WO2004100927A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007021822A2 (en) * 2005-08-09 2007-02-22 The Research Foundation Of State Of University Of New York At Buffalo Compositions and methods of preparation of liposomal microparticulate il-12
US8193246B2 (en) * 2006-12-19 2012-06-05 Marina Biotech, Inc. Lipids and lipid assemblies comprising transfection enhancer elements
ES2373704B1 (es) * 2010-02-18 2013-01-24 Lipotec S.A. Liposomas para el tratamiento de materiales textiles.
CN102133405B (zh) * 2011-03-08 2012-10-17 大连民族学院 脂质体-壳聚糖复合基因载体的制备方法及应用
CA2872779A1 (en) 2012-05-09 2013-11-14 Western University Of Health Sciences Proliposomal testosterone formulations

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4776991A (en) * 1986-08-29 1988-10-11 The United States Of America As Represented By The Secretary Of The Navy Scaled-up production of liposome-encapsulated hemoglobin
WO1992011841A1 (en) * 1991-01-14 1992-07-23 Board Of Regents, The University Of Texas Anti-hiv activity of liposomal nystatin and amphotericin b
US5916588A (en) * 1984-04-12 1999-06-29 The Liposome Company, Inc. Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
WO2000028972A2 (de) * 1998-11-17 2000-05-25 Novosom Gmbh Nanokapseln und verfahren zur herstellung dieser
WO2001034115A2 (de) * 1999-11-09 2001-05-17 Novosom Ag Verfahren zur verkapselung von proteinen oder peptiden in liposomen, mit dem verfahren hergestellte liposomen und deren verwendung
EP1304160A1 (de) * 2001-10-19 2003-04-23 Novosom AG Stabilisierte Mischungen von Liposomen und Emulsionen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5997899A (en) * 1996-10-01 1999-12-07 Skyepharma Inc. Method for producing liposomes with increased percent of compound encapsulated
US7273620B1 (en) * 2002-05-20 2007-09-25 University Of British Columbia Triggered release of liposomal drugs following mixing of cationic and anionic liposomes

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5916588A (en) * 1984-04-12 1999-06-29 The Liposome Company, Inc. Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
US4776991A (en) * 1986-08-29 1988-10-11 The United States Of America As Represented By The Secretary Of The Navy Scaled-up production of liposome-encapsulated hemoglobin
WO1992011841A1 (en) * 1991-01-14 1992-07-23 Board Of Regents, The University Of Texas Anti-hiv activity of liposomal nystatin and amphotericin b
WO2000028972A2 (de) * 1998-11-17 2000-05-25 Novosom Gmbh Nanokapseln und verfahren zur herstellung dieser
WO2001034115A2 (de) * 1999-11-09 2001-05-17 Novosom Ag Verfahren zur verkapselung von proteinen oder peptiden in liposomen, mit dem verfahren hergestellte liposomen und deren verwendung
EP1304160A1 (de) * 2001-10-19 2003-04-23 Novosom AG Stabilisierte Mischungen von Liposomen und Emulsionen

Also Published As

Publication number Publication date
EP1624857A2 (de) 2006-02-15
WO2004100927A2 (de) 2004-11-25
WO2004100927A8 (de) 2005-03-24
US20070053918A1 (en) 2007-03-08
CA2525468A1 (en) 2004-11-25

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