WO2004081166A3 - Nukleotidsequenzen coryneformer bakterien codierend für am l-serinstoffwechsel beteiligte proteine sowie verfahren zur mikrobiellen herstellung von l-serin - Google Patents

Nukleotidsequenzen coryneformer bakterien codierend für am l-serinstoffwechsel beteiligte proteine sowie verfahren zur mikrobiellen herstellung von l-serin Download PDF

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Publication number
WO2004081166A3
WO2004081166A3 PCT/DE2004/000248 DE2004000248W WO2004081166A3 WO 2004081166 A3 WO2004081166 A3 WO 2004081166A3 DE 2004000248 W DE2004000248 W DE 2004000248W WO 2004081166 A3 WO2004081166 A3 WO 2004081166A3
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WO
WIPO (PCT)
Prior art keywords
serine
producing
nucleotide sequences
coryneform bacteria
metabolism
Prior art date
Application number
PCT/DE2004/000248
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English (en)
French (fr)
Other versions
WO2004081166A2 (de
Inventor
Petra Peters-Wendisch
Roman Netzer
Lothar Eggeling
Hermann Sahm
Original Assignee
Forschungszentrum Juelich Gmbh
Petra Peters-Wendisch
Roman Netzer
Lothar Eggeling
Hermann Sahm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forschungszentrum Juelich Gmbh, Petra Peters-Wendisch, Roman Netzer, Lothar Eggeling, Hermann Sahm filed Critical Forschungszentrum Juelich Gmbh
Priority to BRPI0408219-2A priority Critical patent/BRPI0408219A/pt
Priority to JP2006504233A priority patent/JP2006519598A/ja
Priority to US10/549,262 priority patent/US20060204963A1/en
Priority to MXPA05009796A priority patent/MXPA05009796A/es
Priority to AU2004220016A priority patent/AU2004220016B2/en
Priority to EP04710333A priority patent/EP1601773A2/de
Publication of WO2004081166A2 publication Critical patent/WO2004081166A2/de
Publication of WO2004081166A3 publication Critical patent/WO2004081166A3/de
Priority to US12/136,190 priority patent/US8119374B2/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Die Erfindung betrifft Nukleotidsequenzen coryneformer Bakterien codierend für am L-Serinstoffwechsel beteiligte Proteine mit reduzierter bzw. Ausgeschalteter L-Serin-Dehydratase sowie Mikroorganismen und Verfahren zur Herstellung von L-Serin.
PCT/DE2004/000248 2003-03-13 2004-02-12 Nukleotidsequenzen coryneformer bakterien codierend für am l-serinstoffwechsel beteiligte proteine sowie verfahren zur mikrobiellen herstellung von l-serin WO2004081166A2 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
BRPI0408219-2A BRPI0408219A (pt) 2003-03-13 2004-02-12 seqüências de nucleotìdeos de bactérias corineformes codificando proteìnas envolvidas no metabolismo da l-serina bem como microorganismo e processo para a preparação microbiana de l-serina
JP2006504233A JP2006519598A (ja) 2003-03-13 2004-02-12 Ｌ−セリン代謝に関与する蛋白質をコードするコリネ型バクテリアのヌクレオチド配列並びにｌ−セリンの微生物による産生方法
US10/549,262 US20060204963A1 (en) 2003-03-13 2004-02-12 Nucleotide sequences of coryneform bacteria coding for proteins involved in l-serine metabolism and method for producing l-serine
MXPA05009796A MXPA05009796A (es) 2003-03-13 2004-02-12 Secuencias nucleotidas de bacterias corineformes que codifican a las proteinas participantes en el metabolismo de la l-serina y metodo para producir l-serina.
AU2004220016A AU2004220016B2 (en) 2003-03-13 2004-02-12 Nucleotide sequences of coryneform bacteria coding for proteins involved in L-serine metabolism and method for producing L-serine
EP04710333A EP1601773A2 (de) 2003-03-13 2004-02-12 Nukleotidsequenzen coryneformer bakterien codierend f r am l -serinstoffwechsel beteiligte proteine sowie verfahren zur mikrobiellen herstellung von l-serin
US12/136,190 US8119374B2 (en) 2003-03-13 2008-06-10 Nucleotide sequences of coryneform bacteria coded for proteins participating in L-serine metabolism and method for microbial production of L-serine

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10311399A DE10311399A1 (de) 2003-03-13 2003-03-13 Nukleotidsequenzen coryneformer Bakterien codierend für am L-Serinstoffwechsel beteiligte Proteine sowie Verfahren zur mikrobiellen Herstellung von L-Serin
DE10311399.1 2003-03-13

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/136,190 Division US8119374B2 (en) 2003-03-13 2008-06-10 Nucleotide sequences of coryneform bacteria coded for proteins participating in L-serine metabolism and method for microbial production of L-serine

Publications (2)

Publication Number Publication Date
WO2004081166A2 WO2004081166A2 (de) 2004-09-23
WO2004081166A3 true WO2004081166A3 (de) 2005-03-17

Family

ID=32892226

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2004/000248 WO2004081166A2 (de) 2003-03-13 2004-02-12 Nukleotidsequenzen coryneformer bakterien codierend für am l-serinstoffwechsel beteiligte proteine sowie verfahren zur mikrobiellen herstellung von l-serin

Country Status (11)

Country Link
US (2) US20060204963A1 (de)
EP (1) EP1601773A2 (de)
JP (1) JP2006519598A (de)
KR (1) KR20050108387A (de)
AU (1) AU2004220016B2 (de)
BR (1) BRPI0408219A (de)
DE (1) DE10311399A1 (de)
DK (1) DK200900060U3 (de)
MX (1) MXPA05009796A (de)
WO (1) WO2004081166A2 (de)
ZA (1) ZA200508232B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005049527B4 (de) * 2005-10-17 2013-05-08 Forschungszentrum Jülich GmbH Verfahren zur Herstellung von L-Serin, Gensequenz, Vektoren sowie Mikroorganismus
PL2342103T3 (pl) 2008-10-22 2014-11-28 Johnson Controls Tech Co Zamek siedzenia pojazdu
WO2011080301A2 (en) * 2009-12-30 2011-07-07 Metabolic Explorer Strains and method for the production of methionine
KR101500846B1 (ko) * 2013-07-23 2015-03-16 씨제이제일제당 (주) 천연 소고기 풍미 조미소재의 제조 방법
KR101500848B1 (ko) * 2013-07-23 2015-03-09 씨제이제일제당 (주) 천연 뉴트럴 조미소재의 제조 방법
KR101500847B1 (ko) * 2013-07-23 2015-03-16 씨제이제일제당 (주) 천연 코쿠미 조미소재의 제조 방법
KR101500850B1 (ko) * 2013-08-07 2015-03-18 씨제이제일제당 (주) 천연 조미소재 제조를 위한 이노신산 발효액 또는 글루탐산 발효액의 제조 방법
CN107406864B (zh) * 2015-01-27 2022-02-11 化学生物有限公司 用于使用缺乏丝氨酸降解途径的基因工程微生物生产l-丝氨酸的方法
KR102279696B1 (ko) * 2021-04-20 2021-07-20 씨제이제일제당 주식회사 신규한 l-세린 암모니아 분해 효소 변이체 및 이를 이용한 xmp 또는 gmp 생산 방법

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3623952A (en) * 1967-11-29 1971-11-30 Ajinomoto Kk Method of producing l-serine by fermentation
US4528273A (en) * 1983-11-22 1985-07-09 W. R. Grace & Co. Microorganism strains for the fermentative preparation of L-serine
WO2001000843A2 (en) * 1999-06-25 2001-01-04 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding metabolic pathway proteins

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1226541A (en) * 1984-01-13 1987-09-08 Stauffer Chemical Company Mutant strain deficient in l-serine deaminase activity
JP3997631B2 (ja) * 1998-01-12 2007-10-24 味の素株式会社 発酵法によるｌ−セリンの製造法
JP4066543B2 (ja) * 1998-01-12 2008-03-26 味の素株式会社 発酵法によるｌ−セリンの製造法
JP4623825B2 (ja) * 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3623952A (en) * 1967-11-29 1971-11-30 Ajinomoto Kk Method of producing l-serine by fermentation
US4528273A (en) * 1983-11-22 1985-07-09 W. R. Grace & Co. Microorganism strains for the fermentative preparation of L-serine
WO2001000843A2 (en) * 1999-06-25 2001-01-04 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding metabolic pathway proteins

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KUBOTA K: "IMPROVED PRODUCTION OF L SERINE BY MUTANTS OF CORYNEBACTERIUM-GLYCINOPHILUM WITH LESS SERINE DEHYDRATASE EC-4.2.1.13 ACTIVITY", AGRICULTURAL AND BIOLOGICAL CHEMISTRY, vol. 49, no. 1, 1985, pages 7 - 12, XP002287205, ISSN: 0002-1369 *

Also Published As

Publication number Publication date
MXPA05009796A (es) 2005-10-26
AU2004220016B2 (en) 2009-07-16
BRPI0408219A (pt) 2006-02-14
EP1601773A2 (de) 2005-12-07
KR20050108387A (ko) 2005-11-16
AU2004220016A1 (en) 2004-09-23
US8119374B2 (en) 2012-02-21
ZA200508232B (en) 2007-04-25
DK200900060U3 (da) 2009-07-10
US20060204963A1 (en) 2006-09-14
WO2004081166A2 (de) 2004-09-23
US20090061482A1 (en) 2009-03-05
DE10311399A1 (de) 2004-09-23
JP2006519598A (ja) 2006-08-31

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