WO2004080272A3 - Utilisation des genes leprotl1 et ob-rgrp pour le criblage de composes actifs sur la prise ou la perte de poids ou le diabete d'un sujet humain ou animal - Google Patents
Utilisation des genes leprotl1 et ob-rgrp pour le criblage de composes actifs sur la prise ou la perte de poids ou le diabete d'un sujet humain ou animal Download PDFInfo
- Publication number
- WO2004080272A3 WO2004080272A3 PCT/FR2004/000572 FR2004000572W WO2004080272A3 WO 2004080272 A3 WO2004080272 A3 WO 2004080272A3 FR 2004000572 W FR2004000572 W FR 2004000572W WO 2004080272 A3 WO2004080272 A3 WO 2004080272A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- genes
- rgrp
- leprotl1
- diabetes
- loss
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Endocrinology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002518761A CA2518761A1 (fr) | 2003-03-10 | 2004-03-10 | Utilisation des genes leprotl1 et ob-rgrp pour le criblage de composes actifs sur la prise ou la perte de poids ou le diabete d'un sujet humain ou animal |
EP04718992A EP1601973A2 (fr) | 2003-03-10 | 2004-03-10 | Utilisation des genes leprotl1 et ob-rgrp pour le criblage de composes actifs sur la prise ou la perte de poids ou le diabete d un sujet humain ou animal |
US11/221,275 US20060068429A1 (en) | 2003-03-10 | 2005-09-07 | LEPROTL1 and OB-RGRP genes for screening compounds that act on the gain or loss of weight or on diabetes in a human or animal subject |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0302931A FR2852397B1 (fr) | 2003-03-10 | 2003-03-10 | Utilisation des genes leprotl 1 et ob-rgrp pour le criblage de composes actifs sur la prise ou la perte de poids ou le diabete d'un sujet humain ou animal. |
FR03/02931 | 2003-03-10 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/221,275 Continuation US20060068429A1 (en) | 2003-03-10 | 2005-09-07 | LEPROTL1 and OB-RGRP genes for screening compounds that act on the gain or loss of weight or on diabetes in a human or animal subject |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004080272A2 WO2004080272A2 (fr) | 2004-09-23 |
WO2004080272A3 true WO2004080272A3 (fr) | 2004-11-04 |
Family
ID=32893169
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/FR2004/000572 WO2004080272A2 (fr) | 2003-03-10 | 2004-03-10 | Utilisation des genes leprotl1 et ob-rgrp pour le criblage de composes actifs sur la prise ou la perte de poids ou le diabete d'un sujet humain ou animal |
Country Status (5)
Country | Link |
---|---|
US (1) | US20060068429A1 (fr) |
EP (1) | EP1601973A2 (fr) |
CA (1) | CA2518761A1 (fr) |
FR (1) | FR2852397B1 (fr) |
WO (1) | WO2004080272A2 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070050237A1 (en) * | 2005-08-30 | 2007-03-01 | Microsoft Corporation | Visual designer for multi-dimensional business logic |
AU2017359439A1 (en) | 2016-11-08 | 2019-05-23 | Regeneron Pharmaceuticals, Inc. | Antigen-binding proteins that antagonize leptin receptor |
BR112020012011A2 (pt) | 2017-12-18 | 2020-11-24 | Regeneron Pharmaceuticals, Inc. | moléculas de ligação a antígeno biespecífica isolada e de ligação a antígeno biespecífica ou cadeia de imunoglobulina, composição farmacêutica, recipiente ou dispositivo de injeção, ácido nucleico isolado, vetor isolado, célula hospedeira isolada, métodos para tratar uma doença ou condição, para tratar uma condição de lipodistrofia em um sujeito, para produzir uma molécula de ligação a antígeno biespecífica, e, para administrar uma molécula de ligação a antígeno biespecífica isolada ou composição farmacêutica. |
AU2019249273A1 (en) | 2018-04-06 | 2020-10-15 | Regeneron Pharmaceuticals, Inc. | Methods of treatment using a leptin receptor agonist antibody |
-
2003
- 2003-03-10 FR FR0302931A patent/FR2852397B1/fr not_active Expired - Fee Related
-
2004
- 2004-03-10 EP EP04718992A patent/EP1601973A2/fr not_active Withdrawn
- 2004-03-10 WO PCT/FR2004/000572 patent/WO2004080272A2/fr not_active Application Discontinuation
- 2004-03-10 CA CA002518761A patent/CA2518761A1/fr not_active Abandoned
-
2005
- 2005-09-07 US US11/221,275 patent/US20060068429A1/en not_active Abandoned
Non-Patent Citations (3)
Title |
---|
BAILLEUL B ET AL: "THE LEPTIN RECEPTOR PROMOTER CONTROLS EXPRESSION OF A SECOND DISTINCT PROTEIN", 1997, NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, VOL. 25, NR. 14, PAGE(S) 2752-2758, ISSN: 0305-1048, XP002050420 * |
HUANG Y ET AL: "Cloning and characterization of a novel human leptin receptor overlapping transcript-like 1 gene (LEPROTL1)", 2001, BIOCHIMICA ET BIOPHYSICA ACTA. GENE STRUCTURE AND EXPRESSION, ELSEVIER, AMSTERDAM, NL, VOL. 1517, NR. 2, PAGE(S) 327-331, ISSN: 0167-4781, XP004248823 * |
SERON K ET AL: "OB-RGRP AND LEPROTL1 DEFINE A NEW FAMILY OF LIPID RAFT-ASSOCIATED TETRASPANNING MEMBRANE PROTEINS LOCALIZED AT THE TGN AND/OR ENDOSOMES", 2001, BIOLOGY OF THE CELL, VOL. 93, PAGE 227, 2001, XP001154434 * |
Also Published As
Publication number | Publication date |
---|---|
US20060068429A1 (en) | 2006-03-30 |
CA2518761A1 (fr) | 2004-09-23 |
EP1601973A2 (fr) | 2005-12-07 |
FR2852397B1 (fr) | 2005-04-29 |
FR2852397A1 (fr) | 2004-09-17 |
WO2004080272A2 (fr) | 2004-09-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX337782B (es) | Combinaciones de productos activos. | |
WO2008064778A3 (fr) | Combinaisons d'agents actifs insecticides (formononétine + insecticides) | |
EG25314A (en) | Insecticide for agricultural or horticultural use and method of use thereof. | |
MX2007000392A (es) | Derivados de 2-pirrolidona sustituida como fungicidas e insecticidas. | |
WO2003018636A3 (fr) | Compositions et procedes pour traiter le diabete | |
CR20130636A (es) | Combinaciones de productos activos con propiedades namaticidas e insecticidas, basadas en compuestos de trifluorbutenilo | |
WO2004060052A3 (fr) | Souris transgeniques exprimant le cd20 et/ou le cd16 humain(s) | |
AP2006003568A0 (en) | 2-cyanobenzenesulfonamides for combating animal pests. | |
MX2008002802A (es) | Secuencias nucleotidicas que codifican proteinas insecticidas. | |
WO2008080542A3 (fr) | Produit de combinaison destiné à la lutte contre les parasites chez l'animal | |
ECSP056139A (es) | Combinaciones de productos activos con propiedades nematicidas, insecticidas y fungicidas, basadas en compuestos de trifluorbutenilo | |
MX275245B (es) | Composicion de acaros, uso de la misma, metodo para criar un acaro predatorio phytoseiid, sistema de crianza para criar dicho acaro predatorio phytoseiid y metodos para el control biologico de plagas en un cultivo. | |
MXPA05011835A (es) | Agentes para combatir parasitos en animales. | |
WO2005053393A3 (fr) | Combinaisons d'agents comprenant des proprietes insecticides | |
WO2007006591A3 (fr) | Dihalogenation d'hydroxipyridones n,o-disubstituees et leurs utilisations | |
WO2005096819A3 (fr) | Combinaisons de principes actifs a proprietes insecticides | |
TW200513256A (en) | Antifungal and/or antimycotic external preparation for nail | |
WO2007065576A3 (fr) | Association fongicide de principes actifs | |
WO2004080272A3 (fr) | Utilisation des genes leprotl1 et ob-rgrp pour le criblage de composes actifs sur la prise ou la perte de poids ou le diabete d'un sujet humain ou animal | |
EP1376359A3 (fr) | Traitement des informations de configuration pour dispositifs de stockage réseau | |
UA90367C2 (ru) | Зерна зерновых культур, обработанные водной композицией родентицида, способ приготовления композиции для приманки и способ борьбы с грызунами | |
NO20064729L (no) | Parasitticidale midler | |
CU23309B7 (es) | Compuestos anã logos de astrobilurinas y su uso como acaricida e insecticida | |
WO2002023985A3 (fr) | Combinaisons de principes actifs servant a proteger des peaux d'animaux et le cuir | |
AU2003249853A8 (en) | Genetically engineered keratinocytes expressing at least one growth factor and/or activated egf receptor, skin equivalent comprising said keratinocytes and toxicity assay using said keratinocytes |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): BW GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 11221275 Country of ref document: US |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2004718992 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2518761 Country of ref document: CA |
|
WWP | Wipo information: published in national office |
Ref document number: 2004718992 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 11221275 Country of ref document: US |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 2004718992 Country of ref document: EP |