WO2004062533A1 - Stent - Google Patents
Stent Download PDFInfo
- Publication number
- WO2004062533A1 WO2004062533A1 PCT/DE2003/003813 DE0303813W WO2004062533A1 WO 2004062533 A1 WO2004062533 A1 WO 2004062533A1 DE 0303813 W DE0303813 W DE 0303813W WO 2004062533 A1 WO2004062533 A1 WO 2004062533A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- stent
- struts
- strut
- shaped
- circumferential direction
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/9155—Adjacent bands being connected to each other
- A61F2002/91575—Adjacent bands being connected to each other connected peak to trough
Definitions
- the invention relates to a stent with a tubular expandable scaffold according to the features in the preamble of claim 1.
- Stents are used in the treatment of strictures, ie congenital or acquired vascular occlusions or constrictions.
- the stents function in the area of the stenosis as vascular prostheses for supporting the inner walls of the vessel. They are implanted by means of catheter techniques in the place of stenosis.
- stents are known in the art. They are available in metal, plastic and hybrid constructions. They can be self-expanding. Other embodiments can be modified by means of suitable tools, for example balloons, in diameter.
- Stents in the embodiments according to DE 295 21 206 U1 as well as DE 296 08 037 U1 have a tubular support structure made of metal, which consists of several ring segments. These are formed from zig-zag or meandering form over bow sections endlessly adjoining oblique struts. Ring segments adjacent to the longitudinal axis of the stents are coupled via connectors.
- a similar solution is disclosed in WO 96/26689.
- the stents of known type fulfill their function depending on the embodiment more or less satisfactory.
- the scaffolds often either fail to provide the necessary radial forces to adequately withstand a stenosis or are configured to interfere with the function of the vessel.
- the stents also appear to be in need of improvement in terms of load behavior in the body, in particular with regard to bending, torsion and length stability.
- the invention is therefore based on the prior art based on the object to provide a stent that conforms to the shape of a vessel body with uniform pressure distribution in the stenosis area and behaves length-stable even under axial bending or torsional stress in the body.
- the scaffold consists of axially successive ring segments which are formed from undulating oblique struts. Adjacent ring segments are coupled by connectors.
- a connector has a longitudinal portion extending in the longitudinal direction of the stent and a circumferentially directional U-shaped strut portion. The connectors each extend from the top of two V-shaped adjoining OHder oblique struts of a ring segment in the deepest of two V-shaped successive oblique struts of an adjacent ring segment.
- the main point of the invention is the measure that in each case two oblique struts of a ring segment are connected via a pointing in the circumferential direction radial bar and each U-shaped strut portion of a connector has two circumferentially extending transverse struts, which are connected by an aligned parallel to the Stentlangsachse Axialsteg.
- the opening angle between two transverse struts is smaller than the opening angle between two oblique struts.
- the special design of the scaffold ensures high flexibility both in axial bending and in axial rotation.
- the stent is characterized by a geometric fit to the environment. The conformations occur both in axial and in radial expansion without length change. Even when expanding there is no change in length of the scaffold. This ensures the design of the connectors.
- the design of the scaffold is very well adaptable to different anatomical shapes, such as a trachea stent, where a horseshoe shape is favorable. Also, as a bronchial or esophageal stent, the inventively proposed stent is well suited.
- the scaffold is made of a nitinol (nickel-titanium alloy) tube.
- nitinol nickel-titanium alloy
- the production of other metals such as cobalt alloys or stainless steel is possible.
- the length of a cross strut corresponds approximately to the length of a diagonal strut. Also, the lengths of the radial webs and the lengths of the axial webs correspond approximately each other, in both cases a tolerance of ⁇ 3 mm is considered permissible.
- the longitudinal sections of the connectors are dimensioned longer than the oblique struts.
- the angle between a longitudinal section and the transverse strut connected to it is between 90 ° and 100 °.
- the stent according to the invention is characterized in that shape adjustments take place in axial and radial extent, without length changes or constrictions on the support frame.
- the pressure distribution in the stenosis area is even with geometrical form closure to the environment. This means that as a result of the stent geometry, the scaffold wraps around the invading form without building up stress peaks. Outside the loading range, the geometry remains neutral.
- FIG. 1 shows the stent pattern of a stent according to the invention in one
- FIG. 2 shows a detail of the stent pattern according to the figure 1 in an enlarged representation.
- the supporting framework 1 shows the design of a stent according to the invention in a development of its supporting framework 1.
- the supporting framework 1 is self-contained and has a tubular configuration.
- the scaffold 1 is made of metal, in particular of a Nitinol tube and has in Stentlangsachse LA more ring segments 2, 3.
- Each of the ring segments 2, 3 is formed from wavy adjoining oblique struts 4, 5, wherein in each case two oblique struts 4, 5 of a ring segment 2 and 3 are connected via a radial web 6 pointing in calculatorsnchtung U. This contour is referred to herein as V-shaped.
- a connector 7 has a substantially parallel to the longitudinal axis Stentlangsachse LA longitudinal section 8 and a transverse thereto aligned U-shaped strut section 9.
- a strut section 9 in each case comprises two transverse struts 10, 11 extending in the circumferential direction U. These struts are connected by an axial web 12 aligned parallel to the longitudinal axis of the stent LA.
- the U-shaped strut sections 9 are each arranged in the space between two axially spaced adjacent ring segments 2, 3. It can be seen that the connectors 7 are arranged between the ring segments 2, 3 in series one behind the other. In this case, the connectors 7 each extend from the tip 13 of two adjoining each other via the radial web 6 oblique struts 4, 5 of a ring segment 2 in the lowest 14 of two again via a radial web 6 adjacent oblique struts 4, 5 of the adjacent ring segment 2.
- the Longitudinalabimposing 8 is in each case connected to a radial web 6 in the lowest 14 between two oblique struts 4, 5, whereas the U-shaped strut section 9 is affiliated with a short projection 15 to the radial web 6 of a tip 13, wherein the projection 15 in extension to the longitudinal section 8 approximately is aligned at right angles to the radial web 6.
- cross-shaped nodes 16 are formed in the connection areas between the ring segments 2, 3 and the connectors 7.
- the opening angle ⁇ between two transverse struts 10, 11 is smaller than the opening angle ⁇ between two oblique struts 4, 5. Furthermore, it is clear that the length L 1 of a transverse strut 10, 11 is approximately the same length L 2 corresponds to a diagonal strut 4, 5. The lengths L 3 of the radial webs 6 and the lengths L 4 of the axial webs 12 are approximately the same length.
- the longitudinal sections 8, however, are dimensioned longer than the oblique struts 4, 5.
- the angle ⁇ between a longitudinal section 8 and a connected to it cross member 10 and 11 is dimensioned between 90 ° and 100 °.
- the scaffold 1 is able to perform axial expansions (arrow A) and radial expansions (arrow R) without length changes. Unfavorable constrictions are avoided. There is a uniform pressure distribution in the stenosis area with a positive connection to the vessel inner wall. Due to the design of the scaffold 1, the stent is flexible, both in axial bending and in axial rotation. The great flexibility due to the degrees of freedom of the scaffold 1 is again exemplified in FIG. 1 by the arrows P.
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Physics & Mathematics (AREA)
- Vascular Medicine (AREA)
- Optics & Photonics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Prostheses (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003287868A AU2003287868A1 (en) | 2003-01-09 | 2003-11-18 | Stent |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10300475.0 | 2003-01-09 | ||
DE2003100475 DE10300475B4 (de) | 2003-01-09 | 2003-01-09 | Stent mit einem tubulären aufweitbaren Stützgerät |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2004062533A1 true WO2004062533A1 (fr) | 2004-07-29 |
Family
ID=32519753
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DE2003/003813 WO2004062533A1 (fr) | 2003-01-09 | 2003-11-18 | Stent |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU2003287868A1 (fr) |
DE (1) | DE10300475B4 (fr) |
WO (1) | WO2004062533A1 (fr) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007021706A1 (fr) * | 2005-08-16 | 2007-02-22 | Advanced Cardiovascular Systems, Inc. | Modèles de stents polymères |
US9038260B2 (en) | 2006-05-26 | 2015-05-26 | Abbott Cardiovascular Systems Inc. | Stent with radiopaque markers |
EP2881089A1 (fr) * | 2013-12-03 | 2015-06-10 | Centre de Recherche Public Henri Tudor | Stent destiné à être implanté dans des vaisseaux sanguins |
US9198785B2 (en) | 2010-01-30 | 2015-12-01 | Abbott Cardiovascular Systems Inc. | Crush recoverable polymer scaffolds |
WO2016160012A1 (fr) | 2015-04-01 | 2016-10-06 | Yale University | Particules de platine et de fer pour l'adhérence d'agents biologiques sur des implants médicaux |
US9532888B2 (en) | 2006-01-04 | 2017-01-03 | Abbott Cardiovascular Systems Inc. | Stents with radiopaque markers |
US9827119B2 (en) | 2010-01-30 | 2017-11-28 | Abbott Cardiovascular Systems Inc. | Polymer scaffolds having a low crossing profile |
US9999527B2 (en) | 2015-02-11 | 2018-06-19 | Abbott Cardiovascular Systems Inc. | Scaffolds having radiopaque markers |
US10307274B2 (en) | 2011-07-29 | 2019-06-04 | Abbott Cardiovascular Systems Inc. | Methods for uniform crimping and deployment of a polymer scaffold |
US10610387B2 (en) | 2015-06-12 | 2020-04-07 | Abbott Cardiovascular Systems Inc. | Scaffolds having a radiopaque marker and methods for attaching a marker to a scaffold |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE29608037U1 (de) | 1996-05-03 | 1996-07-11 | Sitomed GmbH, 85716 Unterschleißheim | Koronarer Stent |
DE29521206U1 (de) | 1994-07-28 | 1996-09-19 | Brun, Heidi M., Israel | Ein flexibler ausdehnbarer Stent |
US5843175A (en) * | 1997-06-13 | 1998-12-01 | Global Therapeutics, Inc. | Enhanced flexibility surgical stent |
US5853419A (en) * | 1997-03-17 | 1998-12-29 | Surface Genesis, Inc. | Stent |
EP1036550A2 (fr) * | 1999-03-16 | 2000-09-20 | amg Handelsgesellschaft für angewandte Medizin- und Gesundheitstechnik mbH | Stent |
US6206916B1 (en) * | 1998-04-15 | 2001-03-27 | Joseph G. Furst | Coated intraluminal graft |
US20020198593A1 (en) * | 2001-06-11 | 2002-12-26 | Advanced Cardiovascular Systems, Inc. | Intravascular stent |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19937638B4 (de) * | 1999-08-12 | 2006-11-02 | Alveolus Inc. | Trachea-Stent |
DE10150547B4 (de) * | 2001-10-12 | 2007-10-11 | Qualimed Innovative Medizinprodukte Gmbh | Stent |
-
2003
- 2003-01-09 DE DE2003100475 patent/DE10300475B4/de not_active Expired - Lifetime
- 2003-11-18 WO PCT/DE2003/003813 patent/WO2004062533A1/fr not_active Application Discontinuation
- 2003-11-18 AU AU2003287868A patent/AU2003287868A1/en not_active Abandoned
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE29521206U1 (de) | 1994-07-28 | 1996-09-19 | Brun, Heidi M., Israel | Ein flexibler ausdehnbarer Stent |
DE29608037U1 (de) | 1996-05-03 | 1996-07-11 | Sitomed GmbH, 85716 Unterschleißheim | Koronarer Stent |
US5853419A (en) * | 1997-03-17 | 1998-12-29 | Surface Genesis, Inc. | Stent |
US5843175A (en) * | 1997-06-13 | 1998-12-01 | Global Therapeutics, Inc. | Enhanced flexibility surgical stent |
US6206916B1 (en) * | 1998-04-15 | 2001-03-27 | Joseph G. Furst | Coated intraluminal graft |
EP1036550A2 (fr) * | 1999-03-16 | 2000-09-20 | amg Handelsgesellschaft für angewandte Medizin- und Gesundheitstechnik mbH | Stent |
US20020198593A1 (en) * | 2001-06-11 | 2002-12-26 | Advanced Cardiovascular Systems, Inc. | Intravascular stent |
Cited By (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007021706A1 (fr) * | 2005-08-16 | 2007-02-22 | Advanced Cardiovascular Systems, Inc. | Modèles de stents polymères |
US9532888B2 (en) | 2006-01-04 | 2017-01-03 | Abbott Cardiovascular Systems Inc. | Stents with radiopaque markers |
US10070975B2 (en) | 2006-01-04 | 2018-09-11 | Abbott Cardiovascular Systems Inc. | Stents with radiopaque markers |
US9038260B2 (en) | 2006-05-26 | 2015-05-26 | Abbott Cardiovascular Systems Inc. | Stent with radiopaque markers |
US9694116B2 (en) | 2006-05-26 | 2017-07-04 | Abbott Cardiovascular Systems Inc. | Stents with radiopaque markers |
US9358325B2 (en) | 2006-05-26 | 2016-06-07 | Abbott Cardiovascular Systems Inc. | Stents with radiopaque markers |
US9198785B2 (en) | 2010-01-30 | 2015-12-01 | Abbott Cardiovascular Systems Inc. | Crush recoverable polymer scaffolds |
US11324614B2 (en) | 2010-01-30 | 2022-05-10 | Abbott Cardiovascular Systems Inc. | Balloon expanded polymer stent |
US9763818B2 (en) | 2010-01-30 | 2017-09-19 | Abbott Cardiovascular Systems Inc. | Method of crimping stent on catheter delivery assembly |
US9770351B2 (en) | 2010-01-30 | 2017-09-26 | Abbott Cardiovascular Systems Inc. | Crush recoverable polymer scaffolds |
US9827119B2 (en) | 2010-01-30 | 2017-11-28 | Abbott Cardiovascular Systems Inc. | Polymer scaffolds having a low crossing profile |
US9867728B2 (en) | 2010-01-30 | 2018-01-16 | Abbott Cardiovascular Systems Inc. | Method of making a stent |
US10123894B2 (en) | 2010-01-30 | 2018-11-13 | Abbott Cardiovascular Systems Inc. | Method of crimping stent on catheter delivery assembly |
US10307274B2 (en) | 2011-07-29 | 2019-06-04 | Abbott Cardiovascular Systems Inc. | Methods for uniform crimping and deployment of a polymer scaffold |
EP2881089A1 (fr) * | 2013-12-03 | 2015-06-10 | Centre de Recherche Public Henri Tudor | Stent destiné à être implanté dans des vaisseaux sanguins |
US9999527B2 (en) | 2015-02-11 | 2018-06-19 | Abbott Cardiovascular Systems Inc. | Scaffolds having radiopaque markers |
WO2016160012A1 (fr) | 2015-04-01 | 2016-10-06 | Yale University | Particules de platine et de fer pour l'adhérence d'agents biologiques sur des implants médicaux |
US11285211B2 (en) | 2015-04-01 | 2022-03-29 | Yale University | Iron platinum particles for adherence of biologics on medical implants |
US10610387B2 (en) | 2015-06-12 | 2020-04-07 | Abbott Cardiovascular Systems Inc. | Scaffolds having a radiopaque marker and methods for attaching a marker to a scaffold |
US11478370B2 (en) | 2015-06-12 | 2022-10-25 | Abbott Cardiovascular Systems Inc. | Scaffolds having a radiopaque marker and methods for attaching a marker to a scaffold |
Also Published As
Publication number | Publication date |
---|---|
AU2003287868A1 (en) | 2004-08-10 |
DE10300475A1 (de) | 2004-07-22 |
DE10300475B4 (de) | 2008-11-13 |
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