WO2004062533A1 - Stent - Google Patents

Stent

Info

Publication number
WO2004062533A1
WO2004062533A1 PCT/DE2003/003813 DE0303813W WO2004062533A1 WO 2004062533 A1 WO2004062533 A1 WO 2004062533A1 DE 0303813 W DE0303813 W DE 0303813W WO 2004062533 A1 WO2004062533 A1 WO 2004062533A1
Authority
WO
Grant status
Application
Patent type
Prior art keywords
stent
struts
ring
longitudinal
oblique
Prior art date
Application number
PCT/DE2003/003813
Other languages
German (de)
French (fr)
Inventor
Thomas Nissl
Original Assignee
Qualimed Innovative Medizinprodukte Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155Adjacent bands being connected to each other
    • A61F2002/91575Adjacent bands being connected to each other connected peak to trough

Abstract

A stent comprises a tubular extending support structure (1), made from an axial series of annular segments (2, 3). The above are formed by corrugated interconnected inclined arms (4, 5). Adjacent annular segments (2, 3) are connected by means of connectors (7), whereby the connectors (7) run from the tip (13) of two V-shaped interconnected inclined arms (4, 5) of an annular segment (2) into the base (14) of two V-shaped interconnected inclined arms (4, 5) of an adjacent annular segment (3). The inclined arms (4, 5) of an annular segment (2, 3) are connected by means of a radial web (6) with a U pointing in the circumferential direction. The connector (7) has a longitudinal section (8) running in the stent longitudinal axis (LA) and a U-shaped arm section (9) with the U pointing in the circumferential direction. Each U-shaped arm section (9) has two transverse arms (10, 11), running in the U pointing in the circumferential direction, connected by an axial web (12), running parallel to the stent longitudinal axis (LA), whereby the included angle (A) between two transverse arms (10, 11) is smaller than the included angle (B) between two inclined arms (4,5).

Description

stent

The invention relates to a stent comprising a tubular expandable support structure according to the features in the preamble of claim. 1

Stents are used in the treatment of stenoses, so congenital or acquired vascular occlusions or -Verengungen used. The stents act in the area of ​​the stenosis as a vascular prosthesis for supporting the vessel interior walls. They are implanted via catheter techniques in the location of the stenosis.

Various stents are known in the art. They come in metal, plastic and hybrid constructions. They may be self-expanding. Other embodiments may be means of suitable tools, for example, balloons, change in diameter. Stents in the embodiments according to the DE 295 21 206 U1, as well as DE 296 08 037 U1 comprise a tubular scaffold of metal, which consists of several ring segments. These are made zig-zag or meander-shaped over sheet portions to each other endlessly closing oblique struts formed. In the longitudinal axis of the stent adjacent ring segments are coupled by connector. A similar solution is disclosed in WO 96/26689.

The stents known design fulfill their function depending on the embodiment more or less satisfactory. In practice it has been found that the scaffolds often either can not provide the necessary radial forces to sufficiently resist a stenosis, or else are configured so that they obstruct the operation of the vessel. The stent, for that matter load behavior in the body appear, especially regarding bending, twisting and longitudinal stability improvement.

The invention is therefore, starting from the prior art based on the object to provide a stent that conforms to the shape of a vessel body meet at a uniform pressure distribution in the stenosis and also behaves under axial bending or twisting load in the body length stability.

This object is according to the invention in a stent according to the features of patent claim. 1

The scaffold consists of axially sequential ring segments which are formed from undulating together closing oblique struts. Adjacent ring segments are coupled by connector. A connector has a longitudinal axis extending in the stent longitudinal portion and pointing in the Umfangsnchtung U-shaped strut portion. The connectors each extend from the tip of two V-shaped to each other closing oblique struts of a ring segment in the deepest of two V-shaped to each other closing oblique struts of an adjacent ring segment.

Core of the invention provides the measure that two oblique struts of a ring segment are connected via a pointing in Umfangsrichung radial web and each U-shaped strut portion of a connector having two extending in Umfangsnchtung cross struts, which are connected by an aligned parallel to the stent longitudinal axis axial web. Here, the opening angle between two transverse struts is smaller than the opening angle between two oblique struts.

The special design of the supporting structure ensures high flexibility in both axial bending and in axial rotation. The stent is characterized by a geometric form fit to the environment. The shape changes occur in both the axial and radial expansion without change in length. Even when expanding there is no change in length of the support structure. This ensures the design of the connector.

The design of the scaffold is very adaptable to different anatomical shapes, such as a tracheal stent, where a horseshoe shape is favorable. Also called bronchial or esophageal stent of the proposed inventions stent is well suited.

Preferably, the scaffold of a nitinol (nickel-titanium alloy) is - pipe manufactured. Of course, the production of other metals such as cobalt alloys or stainless steel is possible.

Advantageous embodiments of the basic idea of ​​the invention are characterized in the dependent claims 2 to. 5

The length of a cross-member corresponds approximately to the length of a diagonal strut. Also, the lengths of the radial ribs and the lengths of the axial webs correspond approximately to each other, in both cases, a tolerance of ± 3 mm is deemed admissible.

The Longitudinalabschnitte the connector are longer calculated as the oblique struts. The angle between a longitudinal portion and the transverse strut connected thereto sized between 90 ° and 100 °.

As mentioned above, the stent according to the invention is characterized in that the shape adjustments are made in the axial and radial expansion, without changes in length or constrictions on the scaffold. The pressure distribution in the stenosis is uniform in geometric form fit to the environment. This means that the support structure as a result of stent geometry umschmiegt the penetrating form, without building up spikes. Outside the load range, the geometry remains neutral.

The invention is described in more detail below using an exemplary embodiment. Show it:

1, the stent pattern of a stent according to the invention in a

processing and

2 shows a detail of the stent pattern in accordance with the figure 1 in an enlarged representation.

In Figure 1 you can see the design of a stent in a settlement of his scaffold 1. In practice, the support structure 1 is self-contained and has a tubular configuration.

The scaffold 1 is made of metal, in particular from a nitinol tube and has a plurality of ring segments 2, 3 in the stent longitudinal axis LA. Each of the ring segments 2, 3 is made wavy together closing oblique struts 4, 5 are formed, in each case two oblique struts 4, 5 of a ring segment 2 and 3 are connected via a U pointing in Umfangsnchtung radial web. 6 This contour is referred to herein as V-shaped. Among themselves, the ring segments 2, coupled by connectors 7 3 are. A connector 7 has an essentially parallel to the stent longitudinal axis LA longitudinal portion 8 and a transversely thereto aligned U-shaped strut portion configured 9. A strut portion 9 each includes two extending in Umfangsnchtung U cross braces 10, 11. These are connected by a oriented parallel to the stent longitudinal axis LA axial ridge 12th

The U-shaped bar sections 9 are respectively arranged in the space between two adjacent ring segments with axial spacing 2; 3. It can be seen that the connectors 7 are arranged between the ring segments 2, 3 in series one behind the other. Here, the connector 7 together closing oblique struts 4, 5 of a ring segment 2 each extend from the top 13 of two over the radial web 6 in the deepest 14 of two in turn over a radial web 6 adjoin one another oblique struts 4, 5 of the adjacent ring segment 2. The longitudinal portion 8 is each connected to a radial web 6 at the deepest 14 between two oblique struts 4, 5 connected, whereas the U-shaped strut portion 9 is attached with a short projection 15 on the radial web 6 of a tip 13, said projection 15 approximately in the extension to the longitudinal portion 8 is oriented at right angles to the radial web. 6 In this manner, cross-shaped nodes 16 are formed in the connecting regions between the ring segments 2, 3 and the connectors. 7

In particular, with reference to Figure 2, one recognizes that the opening angle α smaller in size between two cross members 10, 11 than the aperture angle beta between two oblique struts 4, 5. Furthermore, it is clear that the length L 1 of a cross-member 10, 11 about the length 2 L of a diagonal strut 4, 5 corresponds. Also, the lengths L 3, the radial webs 6 and the length L 4 of the axial ribs 12 are approximately the same length.

The Longitudinalabschnitte 8, however, are designed to be longer than the oblique struts 4, 5. The angle γ between a longitudinal portion 8 and connected to it a cross bar 10 and 11 is between 90 ° and 100 ° measured.

The scaffold 1 is capable of axial extensions (arrow A) and radial expansion (arrow R) to perform without changes in length. Adverse constrictions are avoided. There is an even distribution of pressure in the stenosis with a form fit to the vessel inner wall. Due to the design of the support structure 1 of the stent is flexible in both the axial deflection as well as axial rotation. The great flexibility due to the degrees of freedom of the support frame 1 is also illustrated in the figure by the arrows P 1 again by way of example.

Bezuαszeichenaufstellunq

1 - support frame

2-ring segment

3- ring segment

4- diagonal strut

5- diagonal strut

6- radial web

7- connector

8- longitudinal portion

9- strut portion

10- crossmember

11 - cross bar

12- axial web

13- peak

14 deepest

15 approach

16- hub

LA stent longitudinal axis

Li length v.10, 11

L 2 "length v.4, 5

L 3 "length v.6

L 4 - length v.12

A- axial extent

P arrow

R- radial expansion

U Umfangsnchtung

α- angle ß "angle rinkel

Claims

claims
1. stent having a tubular, expandable support structure (1) consists of axially successive annular segments (2, 3) extending wavy together closing oblique struts (4, 5) is formed and adjacent ring segments (2, 3) by connectors (7) coupled are, wherein the connector (7) each extending from the tip (13) of two V-shaped to each other closing oblique struts (4, 5) of a ring segment (2) in the deepest (14) of two V-shaped to each other closing oblique struts (4, 5 ) extend an adjacent ring segment (3) and each connector (7) a (in the stent longitudinal direction LA) having extending longitudinal portion (8) and an in Umfangsnchtung (U) facing U-shaped strut portion (9), characterized in that two oblique struts ( 4, 5) of a ring segment (2 and 3, respectively) via an (in Umfangsnchtung U) facing radial web (6) are connected, and each U-shaped strut portion (9) of a connector (7) comprises two Umfangsnchtung (U) extending Que rstreben (10, 11) which are aligned by a parallel to the stent longitudinal axis (LA) axial ridge (12) are connected, wherein the opening angle (α) between two cross-struts (10, 11) is dimensioned smaller than the opening angle (ß) between two oblique struts (4, 5).
2. The stent of claim 1, characterized in that the length (L,) of a transverse strut (10, 11) approximately to the length (L 2) of a diagonal strut (4, 5), with a tolerance of +/- 3 mm.
3. The stent of claim 1 or 2, characterized in that the lengths (L 3) of the radial webs (6) and the lengths (L 4) of the axial webs (12) approximately correspond to each other, with a tolerance of +/- 3 mm.
4. The stent according to one of claims 1 to 3, characterized in that the Longitudinalabschnitte (8) are dimensioned longer than the oblique struts (4, 5). A stent according to any one of claims 1 to 4, characterized in that the angle (γ) between a Logitudinalabschnitt (8) and of its related cross-member (10, bzw.11) between 90 ° and 100 ° measured.
PCT/DE2003/003813 2003-01-09 2003-11-18 Stent WO2004062533A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE10300475.0 2003-01-09
DE2003100475 DE10300475B4 (en) 2003-01-09 2003-01-09 Stent having a tubular expandable support device

Publications (1)

Publication Number Publication Date
WO2004062533A1 true true WO2004062533A1 (en) 2004-07-29

Family

ID=32519753

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2003/003813 WO2004062533A1 (en) 2003-01-09 2003-11-18 Stent

Country Status (2)

Country Link
DE (1) DE10300475B4 (en)
WO (1) WO2004062533A1 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007021706A1 (en) * 2005-08-16 2007-02-22 Advanced Cardiovascular Systems, Inc. Polymeric stent patterns
US9038260B2 (en) 2006-05-26 2015-05-26 Abbott Cardiovascular Systems Inc. Stent with radiopaque markers
EP2881089A1 (en) * 2013-12-03 2015-06-10 Centre de Recherche Public Henri Tudor Stent for implantation into blood vessels
US9198785B2 (en) 2010-01-30 2015-12-01 Abbott Cardiovascular Systems Inc. Crush recoverable polymer scaffolds
WO2016160012A1 (en) 2015-04-01 2016-10-06 Yale University Iron platinum particles for adherence of biologics on medical implants
US9532888B2 (en) 2006-01-04 2017-01-03 Abbott Cardiovascular Systems Inc. Stents with radiopaque markers
US9827119B2 (en) 2010-01-30 2017-11-28 Abbott Cardiovascular Systems Inc. Polymer scaffolds having a low crossing profile
US9999527B2 (en) 2015-02-11 2018-06-19 Abbott Cardiovascular Systems Inc. Scaffolds having radiopaque markers

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE29608037U1 (en) 1996-05-03 1996-07-11 Sitomed Gmbh coronary stent
DE29521206U1 (en) 1994-07-28 1996-09-19 Brun Heidi M A flexible expandable stent
US5843175A (en) * 1997-06-13 1998-12-01 Global Therapeutics, Inc. Enhanced flexibility surgical stent
US5853419A (en) * 1997-03-17 1998-12-29 Surface Genesis, Inc. Stent
EP1036550A2 (en) * 1999-03-16 2000-09-20 amg Handelsgesellschaft für angewandte Medizin- und Gesundheitstechnik mbH Stent
US6206916B1 (en) * 1998-04-15 2001-03-27 Joseph G. Furst Coated intraluminal graft
US20020198593A1 (en) * 2001-06-11 2002-12-26 Advanced Cardiovascular Systems, Inc. Intravascular stent

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19937638B4 (en) * 1999-08-12 2006-11-02 Alveolus Inc. Tracheal Stent
DE10150547B4 (en) * 2001-10-12 2007-10-11 Qualimed Innovative Medizinprodukte Gmbh stent

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE29521206U1 (en) 1994-07-28 1996-09-19 Brun Heidi M A flexible expandable stent
DE29608037U1 (en) 1996-05-03 1996-07-11 Sitomed Gmbh coronary stent
US5853419A (en) * 1997-03-17 1998-12-29 Surface Genesis, Inc. Stent
US5843175A (en) * 1997-06-13 1998-12-01 Global Therapeutics, Inc. Enhanced flexibility surgical stent
US6206916B1 (en) * 1998-04-15 2001-03-27 Joseph G. Furst Coated intraluminal graft
EP1036550A2 (en) * 1999-03-16 2000-09-20 amg Handelsgesellschaft für angewandte Medizin- und Gesundheitstechnik mbH Stent
US20020198593A1 (en) * 2001-06-11 2002-12-26 Advanced Cardiovascular Systems, Inc. Intravascular stent

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007021706A1 (en) * 2005-08-16 2007-02-22 Advanced Cardiovascular Systems, Inc. Polymeric stent patterns
US9532888B2 (en) 2006-01-04 2017-01-03 Abbott Cardiovascular Systems Inc. Stents with radiopaque markers
US9358325B2 (en) 2006-05-26 2016-06-07 Abbott Cardiovascular Systems Inc. Stents with radiopaque markers
US9038260B2 (en) 2006-05-26 2015-05-26 Abbott Cardiovascular Systems Inc. Stent with radiopaque markers
US9694116B2 (en) 2006-05-26 2017-07-04 Abbott Cardiovascular Systems Inc. Stents with radiopaque markers
US9763818B2 (en) 2010-01-30 2017-09-19 Abbott Cardiovascular Systems Inc. Method of crimping stent on catheter delivery assembly
US9198785B2 (en) 2010-01-30 2015-12-01 Abbott Cardiovascular Systems Inc. Crush recoverable polymer scaffolds
US9867728B2 (en) 2010-01-30 2018-01-16 Abbott Cardiovascular Systems Inc. Method of making a stent
US9770351B2 (en) 2010-01-30 2017-09-26 Abbott Cardiovascular Systems Inc. Crush recoverable polymer scaffolds
US9827119B2 (en) 2010-01-30 2017-11-28 Abbott Cardiovascular Systems Inc. Polymer scaffolds having a low crossing profile
EP2881089A1 (en) * 2013-12-03 2015-06-10 Centre de Recherche Public Henri Tudor Stent for implantation into blood vessels
US9999527B2 (en) 2015-02-11 2018-06-19 Abbott Cardiovascular Systems Inc. Scaffolds having radiopaque markers
WO2016160012A1 (en) 2015-04-01 2016-10-06 Yale University Iron platinum particles for adherence of biologics on medical implants

Also Published As

Publication number Publication date Type
DE10300475B4 (en) 2008-11-13 grant
DE10300475A1 (en) 2004-07-22 application

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