WO2004060358A3 - Procede d'encapsulation d'un principe actif liposoluble par preparation d'une emulsion pit et emulsion obtenue - Google Patents

Procede d'encapsulation d'un principe actif liposoluble par preparation d'une emulsion pit et emulsion obtenue Download PDF

Info

Publication number
WO2004060358A3
WO2004060358A3 PCT/FR2003/003900 FR0303900W WO2004060358A3 WO 2004060358 A3 WO2004060358 A3 WO 2004060358A3 FR 0303900 W FR0303900 W FR 0303900W WO 2004060358 A3 WO2004060358 A3 WO 2004060358A3
Authority
WO
WIPO (PCT)
Prior art keywords
emulsion
temperature
soluble substance
encapsulating
preparing
Prior art date
Application number
PCT/FR2003/003900
Other languages
English (en)
Other versions
WO2004060358A2 (fr
Inventor
Luc Jugla
Original Assignee
Cosnessens
Luc Jugla
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cosnessens, Luc Jugla filed Critical Cosnessens
Priority to JP2004564309A priority Critical patent/JP2006517141A/ja
Priority to CA002513273A priority patent/CA2513273A1/fr
Priority to AU2003303610A priority patent/AU2003303610B2/en
Priority to EP03814493A priority patent/EP1578404A2/fr
Priority to US10/537,811 priority patent/US20060134222A1/en
Publication of WO2004060358A2 publication Critical patent/WO2004060358A2/fr
Publication of WO2004060358A3 publication Critical patent/WO2004060358A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Colloid Chemistry (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procédé d'encapsulation d'un principe actif liposoluble dans des nanocapsules par préparation d'une émulsion caractérisé en ce que : a) on dispose d'une phase aqueuse et d'une phase grasse, b) on élève la température des deux phases jusqu'à une température supérieure à la température d'inversion de phase, c) on effectue le mélange des deux phases, d) on incorpore le principe actif liposoluble dans la phase liposoluble, e) on laisse la température s'abaisser jusqu'à la température d'inversion de phase, f) dès que l'inversion de phase est effective et que l'émulsion est en phase continue aqueuse on trempe l'émulsion obtenue pour abaisser sa température et émulsion susceptible d'être obtenue par le procédé caractérisée en ce que la taille des nanocapsules est inférieure en moyenne à 300 nm.
PCT/FR2003/003900 2002-12-26 2003-12-24 Procede d'encapsulation d'un principe actif liposoluble par preparation d'une emulsion pit et emulsion obtenue WO2004060358A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2004564309A JP2006517141A (ja) 2002-12-26 2003-12-24 Ｐｉｔエマルジョンを作成することにより脂溶性活性成分のカプセルを形成する方法及びそのエマルジョン
CA002513273A CA2513273A1 (fr) 2002-12-26 2003-12-24 Procede d'encapsulation d'un principe actif liposoluble par preparation d'une emulsion pit et emulsion obtenue
AU2003303610A AU2003303610B2 (en) 2002-12-26 2003-12-24 Method of encapsulating an active lipid-soluble substance by preparing a PIT emulsion and emulsion obtained
EP03814493A EP1578404A2 (fr) 2002-12-26 2003-12-24 Procede d encapsulation d'un principe actif liposoluble par preparation d' une emulsion pit et emulsion obtenue
US10/537,811 US20060134222A1 (en) 2002-12-26 2003-12-24 Process for encapsulating an active lipid-soluble substance by preparing a pit emulsion and emulsion obtained

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0216723A FR2849379B1 (fr) 2002-12-26 2002-12-26 Encapsulation d'actifs liposolubles
FR02/16723 2002-12-26

Publications (2)

Publication Number Publication Date
WO2004060358A2 WO2004060358A2 (fr) 2004-07-22
WO2004060358A3 true WO2004060358A3 (fr) 2005-07-21

Family

ID=32480214

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2003/003900 WO2004060358A2 (fr) 2002-12-26 2003-12-24 Procede d'encapsulation d'un principe actif liposoluble par preparation d'une emulsion pit et emulsion obtenue

Country Status (8)

Country Link
US (1) US20060134222A1 (fr)
EP (1) EP1578404A2 (fr)
JP (1) JP2006517141A (fr)
CN (1) CN100402019C (fr)
AU (1) AU2003303610B2 (fr)
CA (1) CA2513273A1 (fr)
FR (1) FR2849379B1 (fr)
WO (1) WO2004060358A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8716214B2 (en) * 2003-05-07 2014-05-06 Otc Gmbh Compositions for the targetted release of fragrances and aromas
CN102264348A (zh) * 2008-11-26 2011-11-30 脂蛋白技术有限公司 生物活性提高的白藜芦醇制剂
BE1020154A5 (nl) * 2012-03-22 2013-05-07 Omega Pharma Innovation & Dev Nv Samenstelling voor de behandeling van pediculose en overeenkomstig productiewerkwijze.
KR101645440B1 (ko) * 2014-07-23 2016-08-05 코스맥스 주식회사 다량의 유분을 포함하면서 피부개선효과가 우수한 하이드로겔 마스크의 제조방법 및 이를 통하여 제조된 하이드로겔 조성물
CN109330914B (zh) * 2018-11-28 2022-02-01 广州艾卓生物科技有限公司 一种纳米神经酰胺乳液及其制备工艺和应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756110A (en) * 1994-02-09 1998-05-26 Societe L'oreal S.A. Method for preparing storage-stable, ultrafine oil-in-water emulsion nanopigmented sunscreen/cosmetic compositions
WO2000071676A1 (fr) * 1999-05-25 2000-11-30 Cognis Deutschland Gmbh Utilisation d'emulsions pit dans des procedes de fermentation
EP1093795A1 (fr) * 1999-10-18 2001-04-25 Beiersdorf AG Filtres solaires cosmétiques ou dermatologiques sous forme de macro-émulsions ou micro-émulsions de type H/E contenant un ou plusieurs agents filmogènes sélectés parmi les copolymères de polyvinylpyrrolidone
WO2001064328A1 (fr) * 2000-03-02 2001-09-07 Mainelab Nanocapsules lipidiques, procede de preparation et utilisation comme medicament

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079322A (en) * 1990-05-30 1992-01-07 The Dow Chemical Company Multifunctional cyclobutarene peroxide polymerization initiators

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756110A (en) * 1994-02-09 1998-05-26 Societe L'oreal S.A. Method for preparing storage-stable, ultrafine oil-in-water emulsion nanopigmented sunscreen/cosmetic compositions
WO2000071676A1 (fr) * 1999-05-25 2000-11-30 Cognis Deutschland Gmbh Utilisation d'emulsions pit dans des procedes de fermentation
EP1093795A1 (fr) * 1999-10-18 2001-04-25 Beiersdorf AG Filtres solaires cosmétiques ou dermatologiques sous forme de macro-émulsions ou micro-émulsions de type H/E contenant un ou plusieurs agents filmogènes sélectés parmi les copolymères de polyvinylpyrrolidone
WO2001064328A1 (fr) * 2000-03-02 2001-09-07 Mainelab Nanocapsules lipidiques, procede de preparation et utilisation comme medicament

Also Published As

Publication number Publication date
CN1731986A (zh) 2006-02-08
FR2849379B1 (fr) 2005-02-11
AU2003303610B2 (en) 2009-01-08
AU2003303610A1 (en) 2004-07-29
JP2006517141A (ja) 2006-07-20
FR2849379A1 (fr) 2004-07-02
EP1578404A2 (fr) 2005-09-28
WO2004060358A2 (fr) 2004-07-22
CN100402019C (zh) 2008-07-16
CA2513273A1 (fr) 2004-07-22
US20060134222A1 (en) 2006-06-22

Similar Documents

Publication Publication Date Title
WO2002022086A3 (fr) Application de nanogroupes aqueux sur la peau
ATE512115T1 (de) Monodisperse nanokristalle mit kern/schale und anderen komplexen strukturen sowie herstellungsverfahren dafür
EP1568283A4 (fr) Procede permettant d'inhiber la formation d'acrylamide, et utilisation correspondante
WO2005001889A3 (fr) Points quantiques a alliage de semi-conducteurs et points quantiques a alliage a gradient de concentration, series comprenant ces points quantiques et procedes associes
CA2452577A1 (fr) Capsules molles
ATE401952T1 (de) Umhüllungsverfahren und gekapselte zusammensetzungen
DE60213789D1 (de) Mikrokapseln aus pflanzlichen proteinen
PL367398A1 (en) Microencapsulating of an agricultural active having a high melting point
BR0010185A (pt) Composições para preparo de comida
WO2002069889A3 (fr) Compositions cosmetiques diphasiques gelifiees
IL183753A0 (en) Multiparticulate form of administration, comprising nucleic acid-containing mucoadhesive active ingredients, and method for producing said form of administration
FR2833184B1 (fr) Procede de preparation d'une emulsion multiple de type eau/huile/eau
WO2003101421A8 (fr) Preparations contenant des substances actives, sous forme de film, a stabilite chimique amelioree et procedes de production desdites preparations
CA2254409A1 (fr) Ecran solaire a fps eleve resistant a la transpiration
WO2004060358A3 (fr) Procede d'encapsulation d'un principe actif liposoluble par preparation d'une emulsion pit et emulsion obtenue
WO2005058356A3 (fr) Procedes de fabrication de virus stables au stockage et compositions immunogenes associees
ATE340609T1 (de) Kosmetische zubereitungen kaukaubutter enthaltend
WO2003033557A3 (fr) Copolymeres fluores, leur production et leur utilisation
ATE281881T1 (de) Verfahren zum herstellen einer monodisperse doppelemulsion
AU2003201163A1 (en) Method for the preparation of lariciresinol, cyclolariciresinol and secoisolariciresinol
WO2002026717A8 (fr) Hydroxy acides antagonistes d'integrines
WO2003013478A3 (fr) Procede d'encapsulation d'une substance active
WO2005046635A3 (fr) Procede pour produire des emulsions multiples stables au stockage
WO2003057847A3 (fr) Procedes et substances de modulation de l'enac-beta
WO2005009107A3 (fr) Nouveau produit a usage agricole obtenu a partir de vinasses et de boues issues des distilleries

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2003303610

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 2004564309

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 20038A77299

Country of ref document: CN

WWE Wipo information: entry into national phase

Ref document number: 2003814493

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2513273

Country of ref document: CA

WWP Wipo information: published in national office

Ref document number: 2003814493

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2006134222

Country of ref document: US

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 10537811

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 10537811

Country of ref document: US