WO2004045570A1 - Light protection concentrate with water-soluble polymers - Google Patents

Abstract

A method for the production of an OIW emulsion, characterized in that an O/W emulsion containing a) a lipid phase at a concentration of 20-95 wt. %, b) one or several water-soluble polymers, the overall concentration thereof being 1-80 wt. % in relation to the overall weight of the preparation, and c) one or several UV light protection filters and d) an aqueous phase, in addition to, optionally, other cosmetic and/or dermatological active ingredients, auxiliary substances and additives, are spray-dried and/or freeze-dried.

Description

 Beiersdorf Aktiengesellschaft Hamburg

Sunscreen concentrate with water-soluble polymers

The present invention relates to a process for producing an O / W emulsion, characterized in that an O / W emulsion containing a) a lipid phase in a concentration of 20 to 95% by weight, b) one or more water-soluble polymers in one Total concentration of 1 to 80% by weight, based in each case on the total weight of the preparation, and c) one or more UV light protection filters and d) an aqueous phase, in addition to any other cosmetic and / or dermatological active ingredients, auxiliaries and additives, by spray drying and / or freeze drying.

The desire to look beautiful and attractive is inherently rooted in people. Even if the ideal of beauty has changed over time, the pursuit of a flawless appearance has always been the goal of people. The condition and the appearance of the skin and the appendages of the skin have an essential part in a beautiful and attractive exterior, i.e. of hair and nails.

The skin is the largest organ in humans. Among its many functions (for example for heat regulation and as a sensory organ), the barrier function that prevents the skin (and ultimately the entire organism) from drying out is probably the most important. At the same time, the skin acts as a protective device against the penetration and absorption of external substances and UV radiation. This barrier function is brought about by the epidermis, which as the outermost layer forms the actual protective cover against the environment. At around a tenth of the total thickness, it is also the thinnest layer of the skin.

In order for the skin to fully fulfill its biological functions, it needs regular cleaning and care. The cleaning of the skin serves to remove dirt, sweat and residues of dead skin particles, which can form an ideal breeding ground for pathogens and parasites of all kinds. Skin care products, usually creams, ointments or lotions, mostly serve to moisturize and regrease the skin. Active ingredients that regenerate the skin and, for example, prevent and reduce its premature aging (for example the appearance of wrinkles, wrinkles) are often added to them.

Skin care products usually consist of emulsions. Emulsions are generally understood to mean heterogeneous systems which consist of two immiscible or only to a limited extent miscible liquids, which are usually referred to as phases and in which one of the two liquids is dispersed in the form of very fine droplets in the other liquid. When viewed externally and with the naked eye, emulsions appear homogeneous.

If the two liquids are water and oil and oil droplets are finely distributed in water, then it is an oil-in-water emulsion (O / W emulsion, e.g. milk). The basic character of an O / W emulsion is characterized by the water. A water-in-oil emulsion (W / O emulsion, e.g. butter) is the opposite principle, whereby the basic character is determined by the oil.

The trend away from the paleness towards "healthy, sporty brown skin" has been going on for years. In order to achieve this, people expose their skin to the sun's radiation, since this causes pigment formation in the sense of melanin formation. The ultraviolet radiation of sunlight has However, in addition to the acute damage (sunburn), long-term damage such as an increased risk of skin cancer occurs with excessive exposure to light from the UVB range (wavelength: 280-320 nm) UVB and UVA radiation (wavelength: 320-400 nm) also leads to a weakening of the elastic and collagen fibers of the connective tissue, which leads to numerous phototoxic and photoallergic reactions and results in premature skin aging.

To protect the skin, a number of light protection filters have therefore been developed that can be used in cosmetic preparations. These are UVA and UVB filters summarized in most industrialized countries in the form of positive lists such as Appendix 7 of the Cosmetics Regulation.

Conventional cosmetic and / or dermatological emulsions, for example sunscreen creams or lotions, have a number of disadvantages due to their water content:

■ They are heavy, which leads to higher energy consumption and higher costs during transport.

■ They have a larger volume, which leads to lower transport capacities during transport.

■ In particular, low-viscosity emulsions are much more difficult to store and transport because the preparations can "leak".

■ The application concentrations of the ingredients (e.g. UV filter concentration and thus UV filter performance) are already predetermined for the consumer. An individual adaptation to the conditions at the application site is no longer possible.

It was therefore the object of the present invention to eliminate the disadvantages of the prior art and to develop a “dry” emulsion and a process for producing the same.

The object is surprisingly achieved by a process for producing an O / W emulsion, characterized in that an O / W emulsion containing a) a lipid phase in a concentration of 20 to 95% by weight, 'b) one or more water-soluble Polymers in a total concentration of 1 to 80% by weight, based in each case on the total weight of the preparation, and c) one or more UV light protection filters and d) an aqueous phase, in addition to any other cosmetic and / or dermatological active ingredients, auxiliaries and additives, is dried by spray drying and / or freeze drying.

It is preferred according to the invention if the lipid phase in a concentration of 25 to 90% by weight and particularly preferably in a concentration of 35 to 80 % By weight, based in each case on the total weight of the preparation, is present in the emulsion according to the invention.

It is further preferred according to the invention if one or more water-soluble polymers are contained in a total concentration of 5 to 70% by weight and particularly preferably in a concentration of 10 to 60% by weight, in each case based on the total weight of the emulsion.

Furthermore, it is preferred according to the invention if the water content in the preparation after the spray and / or freeze drying is less than 8% by weight and particularly preferably less than 5% by weight, in each case based on the total weight of the dried emulsion.

O / W emulsions produced by such a method are also in accordance with the invention.

It is particularly surprising that the dry emulsions can be “re-emulsified” by simply adding water, that is to say that an O / W emulsion is formed again, which is usually not the case with “dried” emulsions.

Although Y. Kawashima et al [Int. J. Pharmkonom, 86 (1992) 25-33, Drug Development and Industrial Pharmacy, 18 (9), 919-937 (1992) and Chem. Pharm. Bull. 39 (6) 1528-1531 (1991)] and HG Kristensen et al. [Euro. J. Pharmaceutis and Biopharmaceutics 53 (2002) 147-153 and Int. J. Pharmaceutics 212 (2001) 187-194, 195-202] dried, redispersible emulsions. These emulsions are also stabilized with the help of hydroxypropylmethyl cellulose. However, the emulsions described there are nowhere near as complex as cosmetic and / or dermatological emulsions. Therefore, these writings could not point to the present invention. Compared to the previously known, redispersible emulsions, the emulsions according to the invention have a particularly pleasant feeling on the skin and can be combined with a large number of cosmetic active ingredients, auxiliaries and additives. For example, the emulsions according to the invention contain UV light protection filters which could not previously be incorporated into re-emulsifiable emulsions. The oil phase of the emulsion according to the invention, ie the lipophilic organic constituents, are advantageously chosen from the group of polar oils, for example from the group of lecithins and fatty acid triglycerides, namely the triglycerol esters of saturated and / or unsaturated, branched and / or unbranched alkane carboxylic acids Chain length of 8 to 24, especially 12 to 18 carbon atoms. The fatty acid triglycerides can for example be advantageously selected from the group of synthetic, semi-synthetic and natural oils, such as. B. cocoglyceride, olive oil, sunflower oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, castor oil, wheat germ oil, grape seed oil, safflower oil, evening primrose oil, macadamia nut oil and the like.

According to the invention, z. B. natural waxes of animal and vegetable origin, such as beeswax and other insect waxes and berry wax, shea butter and / or lanolin (wool wax).

In the context of the present invention, further advantageous polar oil components can also be selected from the group of esters from saturated and / or unsaturated, branched and / or unbranched alkane carboxylic acids with a chain length of 3 to 30 carbon atoms and saturated and / or unsaturated, branched and / or unbranched alcohols with a chain length of 3 to 30 C atoms and from the group of esters from aromatic carboxylic acids and saturated and / or unsaturated, branched and / or unbranched alcohols with a chain length of 3 to 30 C atoms. Such ester oils can then advantageously be selected from the group octyl palmitate, octyl co-coat, octyl isostearate, octyl dodeceyl myristate, octyl dodecanol, cetearyl isononanoate, isopropyl myristate, isopropyl palmitate, isopropyl stearate, isopropyl oleate, n-butyl stearate, n-stonolate, n-stonolate, n-stonyl-n-stonate, 2-ethylhexyl palmitate, 2-ethylhexyl laurate, 2-hexyldecyl stearate, 2-octyldodecyl palmitate, stearyl heptanoate, oleyl oleate, olerlerucate, erucyl oleate, erucylerucate, tridecyl stearate, tridecyltrimic gemellate, as well as synthetic such as. B. Jojoba oil.

Furthermore, the oil phase can advantageously be selected from the group of dialkyl ethers and dialkyl carbonates. B. dicaprylyl ether (Cetiol OE) and / or dicaprylyl carbonate, for example that available under the trade name Cetiol CC from Cognis.

It is further preferred pentylglykoldiheptanoat the one or more oil components from the group consisting of isoeicosane, neopentyl, propylene glycol dicaprylate / dicaprate, caprylic / capric / Diglyceryl- succinate, butylene glycol dicaprylate / dicaprate, cocoglycerides (z. B. Myritol® 331 by Henkel), Cι ₂ - ₁₃ -Alkyllactate, Di-Cι ₂ - ₁₃ -alkyl tartrate, triisostearin, dipentaerythrityl hexacaprylate / hexacaprate, propylene glycol monoisostearate, tricaprylin, dimethyl isosorbide. It is particularly advantageous if the oil phase of the formulations according to the invention has a content of C ₁₂ -is alkyl benzoate or consists entirely of this.

Advantageous oil components are also e.g. B. butyl octyl salicylate (for example that available under the trade name Hallbrite BHB from CP Hall), hexadecyl benzoate and butyl octyl benzoate and mixtures thereof (Hallstar AB) and / or diethyl hexyl naphthalate (Corapan®TQ from Haarmann & Reimer).

Any mixtures of such oil and wax components can also be used advantageously for the purposes of the present invention.

According to the invention, the lipid phase can contain the polar oil components in a concentration of up to 80% by weight based on the total weight of the lipid phase. The weight given relates to the composition of the preparation before drying by means of freeze and / or spray drying.

The oil phase can also advantageously also contain non-polar oils, for example those selected from the group of branched and unbranched hydrocarbons and waxes, in particular mineral oil, petroleum jelly (petrolatum), paraffin oil, squalane and squalene, polyolefins, hydrogenated polyisobutenes and isohexa- decane. Among the polyolefins, polydecenes and hydrogenated polyisobutenes are the preferred substances.

The non-polar oil components can advantageously be present in the emulsions according to the invention in a concentration of up to 80% by weight, based on the total weight of the lipid phase. The weight specification refers to the Composition of the preparation before drying by freeze and / or spray drying.

The oil phase can advantageously also have a content of cyclic or linear silicone oils or consist entirely of such oils, although it is preferred to use an additional content of other oil phase components in addition to the silicone oil or the silicone oils.

Silicone oils are high-molecular synthetic polymeric compounds in which silicon atoms are linked in a chain and / or network-like manner via oxygen atoms and the remaining valences of silicon by hydrocarbon residues (mostly methyl, more rarely ethyl, propyl, phenyl groups, etc.) are saturated. The silicone oils are systematically referred to as polyorganosiloxanes. The methyl-substituted polyorganosiloxanes, which are the most important compounds of this group in terms of quantity and are characterized by the following structural formula

are also known as polydimethylsiloxane or dimethicone (INCI). Dimethicone is available in different chain lengths or with different molecular weights.

Particularly advantageous polyorganosiloxanes for the purposes of the present invention are, for example, dimethylpolysiloxanes [polydimethylsiloxane)], which are available, for example, under the trade names Abil 10 to 10,000 from Th. Goldschmidt. Phenylmethylpolysiloxanes (INCI: phenyl dimethicone, phenyl trimethicone), cyclic silicones (octamethylcyclotetrasiloxane or decamethylcyclopentasiloxane), which according to INCI are also referred to as cyclomethicones, are also advantageous, amino-modified silicones (INCI: amodimethicone and silicone wax). B. polysiloxane-polyalkylene copolymers (INCI: stearyl dimethicone and cetyl dimethicone) and dialkoxydimethyl polysiloxanes (stearoxy dimethicone and behenoxy stearyl dimethicone), which are available as different Abil-Wax types from Th. Goldschmidt. However, other silicone oils can also be used advantageously for the purposes of the present invention, for example Cetyldimethicone, hexamethylcyclotrisiloxane, polydimethylsiloxane, poly (methylphenylsiloxane).

Silicones which are particularly preferred according to the invention are dimethicone and cyclomethicone.

The silicone oil content of the lipid phase can advantageously be 20 to 100% by weight and particularly preferably 30 to 60% by weight, in each case based on the total weight of the lipid phase.

Water-soluble polymers which are advantageous according to the invention can advantageously be inventively selected from the group of water-soluble or dispersible film-formers (for example polyurethanes, dimethicone copolyol polyacrylates, polyvinylpyrrolidone-vinyl acetates PVP / VA, polyvinylpyrrolidones (PVP), see below) and from the group of hydrocolloids (for example Agar-agar, carrageenan, tragacanth, gum arabic, alginates, pectins, polyoses, guar flour, locust bean gum, starch, dextrins, polysaccharide-N-alkyl urethanes, inulin carbamates, gelatin, casein, cellulose ethers, hydroxyethyl and - propyl cellulose derivatives, polysaccharide derivatives , Polyacrylic and polymethacrylic compounds, ammonium acryloyldimethyl taurates / vinyl pyrrolidone copolymers and ammonium polyacrylic dimethyl tauramides, vinyl polymers, polycarboxylic acids, polyethers, polyimines, polyamides, polysilicic acids, clay minerals, zeolites, silicas, see below).

Hydrocolloids preferred according to the invention are, for example, methyl celluloses, as the methyl ethers of cellulose are referred to. They are characterized by the following structure

in which R can represent a hydrogen or a methyl group.

Particularly advantageous for the purposes of the present invention are the cellulose mixed ethers, which are generally also referred to as methyl celluloses and which, in addition to a dominant content of methyl, also contain 2-hydroxyethyl, 2-hydroxypropyl or 2-hy- contain droxybutyl groups. Particularly preferred hydroxypropylmethyl celluloses (HPMC) have an average molar mass M _m <50,000 g mol ^"1 and are, for example, under the name Pharmacoat 603, Pharmacoat 606 and Pharmacoat 645 or under the name Metolose 65 SH 50 or Metolose 60 SH 50 from FA Shin Etsu available.

Also preferred are (hydroxypropyl) methyl celluloses, for example those sold under the trade name Methocel E4M by Dow Chemical Comp. available.

Also advantageous according to the invention is sodium carboxymethyl cellulose, the sodium salt of the glycolic acid ether of cellulose, for which R in structural formula I can be a hydrogen and / or CH2-COONa. Particularly preferred is the sodium carboxymethyl cellulose available under the trade name Natrosol Plus 330 CS from Aqualon, also referred to as cellulose gum.

It is furthermore according to the invention if such an O / W emulsion according to the invention contains water-soluble cosmetic and / or dermatological active ingredients, auxiliaries and / or additives.

According to the invention is the process for producing an O / W emulsion according to the invention, which is characterized in that an O / W emulsion according to the invention dried by spray drying and / or freeze drying in a mixing device with water-soluble and / or volatile active, auxiliary and / or additives are mixed.

According to the invention, “volatile” means that these compounds have a boiling point of at most 30 ° C.

An O / W emulsion which is produced by such a process is also in accordance with the invention.

The emulsion according to the invention can thus contain water-soluble and / or water-dispersible ingredients according to the invention. These are advantageously added to the preparation according to the invention after freeze or spray drying. The emulsion according to the invention can contain water-soluble ingredients according to the invention, for example alcohols, diols or polyols of low C number, and their ethers, preferably ethanol, isopropanol, propylene glycol, ethylene glycol, ethylene glycol monoethyl or monobutyl ether, propylene glycol monomethyl, monoethyl or mono butyl ether, diethylene glycol monomethyl or monoethyl ether and analog products.

The emulsions can contain one or more polyols selected from the group sorbitol, propylene glycol and butylene glycol.

The polyols which are particularly preferred according to the invention are sorbitol and mannitol.

It is advantageous in the sense of the present invention if the cosmetic and / or dermatological emulsion according to the invention has a total amount of polyols of 5.0 to 40.0% by weight, preferably 7.5 to 35.0% by weight and very particularly preferably from 10.0 to 25.0% by weight, based in each case on the total weight of the preparation. The weight data relate to the composition of the preparation before drying by means of freeze and / or spray drying.

The emulsion according to the invention is advantageously used as a sunscreen. It is also advantageous for the purposes of the present invention to produce cosmetic and dermatological preparations, the main purpose of which is not protection from sunlight, but which nevertheless contain UV protection substances. So z. For example, UV-A or UV-B filter substances are usually incorporated into day creams or makeup products. UV protection substances, like antioxidants and, if desired, preservatives, also provide effective protection of the preparations themselves against spoilage. Furthermore, cosmetic and dermatological preparations which are in the form of a sunscreen are favorable.

Accordingly, the preparations in the sense of the present invention preferably contain at least one UV-A and / or UV-B filter substance. The formulations can, although not necessary, optionally also contain one or more organic and / or inorganic pigments as UV filter substances. Preferred inorganic pigments are metal oxides and / or other metal compounds which are sparingly soluble or insoluble in water, in particular oxides of titanium (Ti0 ₂ ), zinc (ZnO), iron (e.g. Fe ₂ 0 ₃ ), zirconium (Zr0 ₂ ), silicon ( Si0 ₂ ), manganese (e.g. MnO), aluminum (Al ₂ 0 ₃ ), cerium (e.g. Ce ₂ 0 ₃ ), mixed oxides of the corresponding metals and mixtures of such oxides, as well as the sulfate of barium (BaS0 ).

The titanium dioxide pigments can be present both in the rutile and anatase crystal modification and, for the purposes of the present invention, can advantageously be surface-treated (“gecoatef”), for example forming or maintaining a hydrophilic, amphiphilic or hydrophobic character. This surface treatment can consist in that the pigments are provided with a thin hydrophilic and / or hydrophobic inorganic and / or organic layer by methods known per se. For the purposes of the present invention, the various surface coatings can also contain water.

Coated and uncoated titanium dioxides described can also be used in the form of the present invention in the form of commercially available oily or aqueous predispersions. Dispersing aids and / or solubilizing agents can advantageously be added to these predispersions. The titanium dioxides according to the invention are distinguished by a primary particle size between 10 nm to 150 nm.

For the purposes of the present invention, particularly preferred titanium dioxides are the MT-100 Z and MT-100 TV from Tayca Corporation, Eusolex T-2000 and Eusolex TS from Merck and the titanium dioxide T 805 from Degussa.

For the purposes of the present invention, zinc oxides can also be used in the form of commercially available oily or aqueous predispersions. Draw suitable zinc oxide particles and predispersions of zinc oxide particles according to the invention are characterized by a primary particle size of <300 nm and are available under the following trade names from the companies listed:

Z-Cote HP1 from BASF and zinc oxide NDM from Haarmann & Reimer are particularly preferred zinc oxides for the purposes of the invention.

The total amount of one or more inorganic pigments in the finished cosmetic preparation is advantageously selected from the range 0.1% by weight to 25% by weight, preferably 0.5% by weight to 18% by weight.

An advantageous organic pigment for the purposes of the present invention is 2,2'-methylene-bis- (6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) phenol) [INCI: bisoctyl-triazole], which is available under the trade name Tinosorb® M from CIBA-Chemicals GmbH.

Advantageous UV-A filter substances for the purposes of the present invention are dibenzoyl methane derivatives, in particular 4- (tert-butylH'-red ⁿ ° xydibenzoyl methane (CAS No. 70356-09-1), which is available from Givaudan under the Parsol brand ^® 1789 and is sold by Merck under the trade name Eusolex® 9020.

Further advantageous UV-A filter substances are the phenylene-1,4-bis (2-benzimidazyl) -3,3'-5,5'-tetrasulfonic acid and its salts, especially the corresponding sodium, potassium or triethanolammonium salts , in particular the phenylene-1,4-bis- (2-benzimidazyl) -3,3'-5,5'-tetrasulfonic acid bis-sodium salt with the INCI name bisimidazylate, which is available, for example, under the trade name Neo Heliopan AP from Haarmann & Reimer is available. Also advantageous are the 1,4-di (2-oxo-10-sulfo-3-bornylidenemethyl) benzene and its salts (especially the corresponding 10-sulfato compounds, especially the corresponding sodium, potassium or triethanolammonium salt) , which is also known as benzene-1,4-di (2-oxo-3-bornylidenemethyl-10-surfonic acid).

Further advantageous UV-A filter substances are hydroxybenzophenones, which are characterized by the following structural formula:

Wonn

• R ¹ and R ² independently of one another are hydrogen, -CC-C2o-alkyl, C ₃ -C -o-cycloalkyl or C ₃ -C- ₀ -cycloalkenyl, the substituents R ¹ and R ² together with the nitrogen atom to which they are bound , can form a 5- or 6-ring and

• R ^{3 is} a C ₁ -C ₂ o-alkyl radical.

A particularly advantageous hydroxybenzophenone in the sense of the present invention is 2- (4'-diethylamino-2'-hydoxybenzoyl) benzoic acid hexyl ester (also: aminobenzophenone), which is characterized by the following structure:

and is available under the trade name Uvinul A Plus from BASF. Advantageous UV filter substances in the sense of the present invention are also so-called broadband filters, ie filter substances that absorb both UV-A and UV-B radiation.

Advantageous broadband filters or UV-B filter substances are, for example, bis-resorcinyltriazine derivatives with the following structure:

where R ¹ , R ² and R ^{3 are} independently selected from the group of branched and unbranched alkyl groups having 1 to 10 carbon atoms or represent a single hydrogen atom. Particularly preferred are the 2,4-bis - {[4- (2-ethylhexyloxy) -2-hydroxy] phenyl} -6- (4-methoxyphenyl) -1,3,5-triazine (INCI: Aniso triazine ), which is available under the trade name Tinosorb® S from CIBA-Chemicals GmbH.

Particularly advantageous preparations within the meaning of the present invention, which are distinguished by a high or very high UV-A protection, preferably contain a plurality of UV-A and / or broadband filters, in particular dibenzoylmethane derivatives [for example 4- (tert-butyl) -4 ^, -methoxydibenzoylmethane], benzotriazole derivatives [for example 2,2'-methylene-bis- (6- (2H-benzotriazol-2-yl) -4- (1, 1, 3,3-tetramethylbutyl) phenol )], Phenylene-1,4-bis (2-benzimidazyl) -3 _> 3'-5,5'-tetrasulfonic acid and / or its salts, the 1,4-di (2-oxo-10-sulfo-3 -bomylidene-methyl) -benzene and / or its salts and / or the 2,4-bis - {[4- (2-ethylhexyloxy) -2-hydroxy] phenyl} -6- (4-methoxyphenyl) - 1, 3,5-triazine, individually or in any combination with one another.

Also other UV filter substances, which the structural motif

have, are advantageous UV filter substances for the purposes of the present invention, for example, the descriptions in the European Published Patent Application EP 570 838 A1 _¬ NEN s-triazine derivatives, the chemical structure by the generic formula

is reproduced, whereby

R is a branched or unbranched CC ₁₈ alkyl, C ₅ -C ₁₂ cycloalkyl radical optionally substituted with one or more C ₄ - alkyl groups _¬ represents,

X represents an oxygen atom or an NH group, t is a branched or unbranched CC ^ alkyl radical, a C ₅ -C ₁₂ cycloalkyl radical, optionally substituted with one or more dC ₄ alkyl groups, or a hydrogen atom, an alkali metal atom Ammonium group or a 'group of formula

means in which

A represents a branched or unbranched CrC ₁₈ alkyl radical, a C ₅ -C ₂ cycloalkyl or aryl radical, optionally substituted by one or more CC ₄ alkyl groups, R _{3 represents} a hydrogen atom or a methyl group, n is a number 1 to 10 represents a branched or unbranched C 1 -C ₈ alkyl radical, a C ₅ -Ci2 cycloalkyl radical, optionally substituted with one or more dC - alkyl groups, when X represents the NH group, and a branched or unbranched CC ₁₈ alkyl radical, a C ₅ -C ₂ cycloalkyl radical, optionally substituted with one or more CC ₄ alkyl groups, or a hydrogen atom, an alkali metal atom, an ammonium group or a group of the formula

means in which

A represents a branched or unbranched Ci-C-iβ-alkyl radical, a Cs-Cι- ₂ cycloalkyl or aryl radical, optionally substituted with one or more C ₁ -C ₄ alkyl groups,

R _{3 represents} a hydrogen atom or a methyl group, n represents a number from 1 to 10 when X represents an oxygen atom.

A particularly preferred UV filter substance in the sense of the present invention is also an asymmetrically substituted s-triazine, the chemical structure of which is represented by the formula

is reproduced, which is also referred to below as dioctylbutylamidotriazon (INCI: dioctylbutamidotriazone) and is available under the trade name UVASORB HEB from Sigma 3V.

Also advantageous in the sense of the present invention is a symmetrically substituted s-triazine, the 4,4 ', 4 "- (1,3,5-triazine-2,4,6-triyltriimino) -t'is-benzoic acid tris ( 2-ethylhexyl ester), synonymous: 2,4,6-tris [anilino- (p-carbo-2'-ethyl-1'-hexyloxy)] - 1,3,5-triazine (INCI: octyl triazone) , which is sold by BASF Aktiengesellschaft under the trade name UVINUL® T 150.

European laid-open specification 775698 also describes bis-resorcinyltriazine derivatives which are preferably to be used and whose chemical structure is represented by the generic formula

is reproduced, wherein Ri, R ₂ and Ai represent a wide variety of organic radicals.

For the purposes of the present invention, 2,4-bis - {[4- (3-sulfonato) - 2-hydroxypropyloxy) -2-hydroxy] phenyl} -6- (4-methoxyphenyl) -1, 3,5-triazine sodium salt, the 2,4-bis - {[4- (3- (2-propyloxy) -2-hydroxypropyloxy) -2-hydroxy] phenyl} -6- (4-methoxyphenyl ) -1, 3,5-triazine, the 2,4-bis - {[4- (2-ethylhexyloxy) -2-hydroxy] phenyl} -6- [4- (2-methoxyethyl carboxyl ) -phenylamino] -1, 3,5-triazine, the 2,4-bis - {[4- (3- (2-propyloxy) -2-hydroxypropyloxy) -2-hydroxy] phenyl} -6- [4- (2-ethylcarboxyl) phenylamino] -1, 3,5-triazine, the 2,4-bis - {[4- (2-ethylhexyloxy) -2-hydroxy] phenyl} -6 - (1-methyl-pyrrol-2-yl) -1, 3,5-triazine, the 2,4-bis - {[4-tris (trimethylsiloxysilylpropyloxy) -2-hydroxy] phenyl} -6- ( 4-methoxyphenyl) - 1, 3,5-triazine, the 2,4-bis - {[4- (2 "-methylpropenyloxy) -2-hydroxy] phenyl} -6- (4-methoxyphenyl) -1 , 3,5-triazine and 2,4-bis - {[4- (1 ', 1', ^1, 3 ', ^5, 5' 5 _'t Heptamethylsiloxy-2 "-methyl-propyloxy) - 2-hydroxy] phenyl} -6- (4-methoxyphenyl) -1,3,5-triazine. An advantageous broadband filter in the sense of the present invention is the 2,2'-methylene-bis- (6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) phenol), which is available under the trade name Tinosorb® M from CIBA-Chemicals GmbH.

Another advantageous broadband filter for the purposes of the present invention is 2- (2H-benzotriazol-2-yl) -4-methyl-6- [2-methyl-3- [1,3,3,3-tetramethyl-1 - [( trimethylsilyl) oxy] disiloxanyl] propyl] phenol (CAS No .: 155633-54-8) with the INCI name Drometrizole Trisiloxane.

The UV-B and / or broadband filters can be oil-soluble or water-soluble. Advantageous oil-soluble UV-B and / or broadband filter substances are e.g. B .:

■ 3-benzylidene camphor derivatives, preferably 3- (4-methylbenzylidene) camphor, 3-benzylidene camphor;

■ 4-aminobenzoic acid derivatives, preferably 4- (dimethylamino) benzoic acid (2-ethylhexyl) ester, 4- (dimethylamino) benzoic acid amyl ester;

- 2,4,6-trianilino- (p-carbo-2'-ethyl-1'-hexyloxy) -1, 3,5-triazine;

■ Esters of benzalmalonic acid, preferably 4-methoxybenzalmalonic acid di (2-ethylhexyl) esteπ

■ esters of cinnamic acid, preferably 4-methoxycinnamic acid (2-ethylhexyl) ester, 4-methoxycinnamic acid isopentyl ester; ■ Derivatives of benzophenone, preferably 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone

■ and UV filters bound to polymers.

Advantageous water-soluble UV-B and / or broadband filter substances are e.g. B .:

■ salts of 2-phenylbenzimidazole-5-sulfonic acid, such as its sodium, potassium or triethanolammonium salt, and the sulfonic acid itself;

■ Sulfonic acid derivatives of 3-benzylidene camphor, such as. B.4- (2-oxo-3-bornylidene methyl) benzenesulfonic acid, 2-methyl-5- (2-oxo-3-bornylidene methyl) sulfonic acid and their salts.

Particularly advantageous UV filter substances which are liquid at room temperature for the purposes of the present invention are homomenthyl salicylate (INCI: homosalate), 2-ethylhexyl-2-hydroxybenzoate (2-ethylhexyl salicylate, octyl salicylate, INCI: octyl salicylate), 4-isopropyl benzyl salicylate, and preferably esters of cimyl 4-methoxycinnamic acid (2-ethylhexyl) ester (2-ethylhexyl-4-methoxycinnamate, INCI: octyl methoxycinnamate) and 4-methoxycinnamic acid isopentyl ester (isopentyl-4-methoxycinnamate, INCI: isoamyl p-methoxycinnamate), 3- (4- ( 2,2-bis-ethoxycarbonylvinyl) -phenoxy) propenyl) -methoxysiloxane / dimethylsiloxane - copolymer (INCI: Dimethicodiethylbenzalmalonat) which is available, for example, under the trade name Parsol® SLX from Hoffmann La Röche.

A further light protection filter substance according to the invention to be used advantageously is ethylhexyl-2-cyano-3,3-diphenylacrylate, obtainable (octocrylene) from BASF under the name Uvinul ^® N 539th

A particularly preferred benzoxazole derivative according to the invention is 2,4-bis- [5-1 (dimethylpropyl) benzoxazol-2-yl- (4-phenyl) -imino] -6- (2-ethylhexyl) -imino-1 , 3,5-triazine with CAS No. 288254-16-0, which is characterized by the structural formula

distinguished and is available from 3V Sigma under the trade name Uvasorb® K2A.

It can also be of considerable advantage to use polymer-bound or polymeric UV filter substances in preparations according to the present invention, in particular those as described in WO-A-92/20690.

The list of the UV filters mentioned, which can be used in the sense of the present invention, should of course not be limiting.

The preparations according to the invention advantageously contain the substances which absorb UV radiation in the UV-A and / or UV-B range in a total amount of, for. B. 0.1 wt .-% to 80 wt .-%, preferably 0.5 to 70 wt .-%, in particular 1.0 to 60 wt .-%, each based on the total weight of the preparations to cosmetic preparations To provide that protect the hair or skin from the entire range of ultraviolet radiation. They can also serve as sunscreens for the hair or skin.

The weight data relate to the composition of the preparation before drying by means of freeze and / or spray drying. The weight data relate to the composition of the preparation before drying by means of freeze and / or spray drying. Particularly preferred embodiments of the present invention contain one or more triazine derivatives, dibenzoylmethane derivatives, UV filters which are liquid at room temperature and / or inorganic pigments, in particular titanium dioxide, as UV filters.

It may also be advantageous to incorporate film formers into the emulsion according to the invention, for example in order to improve the water resistance of the preparations or to increase the UV protection performance (UV-A and / or UV-B boosting). Both water-soluble or dispersible and fat-soluble film formers are suitable, in each case individually or in combination with one another.

Advantageously water-soluble or dispersible film formers according to the invention, which can also be used as water-soluble polymers according to the invention, are e.g. B. Polyurethanes (e.g. Avalure® types from Goodrich), Dimethicone Copolyol Polyacrylate (Silsoft Surface® from the Witco Organo Silicones Group), PVPΛ / A (VA = vinyl acetate) copolymer (Luviscol VA 64 Powder from BASF) etc ,

Advantageous water-soluble film formers are e.g. B., the film formers from the group of polymers based on polyvinylpyrrolidone (PVP)

Particularly preferred are copoly of polyvinylpyrrolidone, for example the PVP hexadecene copolymer and the PVP eicosen copolymer, which are available under the trade names Antaron V216 and Antaron V220 from GAF Chemicals Cooperation, as well as the Tricontayl PVP and the like.

According to the invention, the usual antioxidants can be used in the emulsion.

The antioxidants are advantageously selected from the group consisting of amino acids (eg glycine, histidine, tyrosine, tryptophan) and their derivatives, imidazoles (eg urocanic acid) and their derivatives, peptides such as D, L-carnosine, D-camosine, L- Camosin and its derivatives (e.g. anserine), carotenoids, carotenes (e.g. α-carotene, β-carotene, lycopene) and their derivatives, aurothioglucose, propylthiouracil and other thiols (e.g. Thiored- oxine, glutathione, cysteine, cystine, cystamine and their glycosyl, N-acetyl, methyl, ethyl, propyl, amyl, butyl and lauryl, palmitoyl, oleyl, γ-linoleyl, cholesteryl and glyceryl esters) and their salts, dilauryl thiodipropionate, distearyl thiodipropionate, thiodipropionic acid and their derivatives (esters, ethers, peptides, lipids, nucleotides, nucleosides and salts) as well as (metal) chelators (e.g. α-hydroxy fatty acids, palmitic acid, phytin acid, lactoferrin), α-hydroxy acids (e.g. citric acid, lactic acid, malic acid), humic acid, bile acid, bile extracts, bilirubin, biliverdin, EDTA, EGTA and their derivatives, unsaturated fatty acids and their derivatives (e.g. γ-linolenic acid, linoleic acid, oleic acid), Folic acid and its derivatives, alanine diacetic acid, flavonoids, polyphenols, catechins, vitamin C and derivatives (eg ascorbyl palmitate, Mg ascorbyl phosphate, ascorbate acetate), tocopherols and derivatives (eg vitamin E acetate), and coniferyl benzoate of benzoin, rutinic acid and their derivatives, ferulic acid and its derivatives, butylhydroxytoluene, butylhydroxyanisole, nordihydroguajakharzäure, nordihydroguajaretic acid, trihydroxybutyrophenone, uric acid and its derivatives, mannose and its derivatives, zinc and its derivatives (eg ZnO, ZnS0) selenium and its derivatives ), Stilbenes and their derivatives (eg stilbene oxide, trans-stilbene oxide) and the derivatives suitable according to the invention (salts, esters, ethers, sugars, nucleotides, nucleosides, peptides and lipids) of these active substances.

The amount of the antioxidants (one or more compounds) in the preparations is preferably 0.001 to 30% by weight, particularly preferably 0.025-6.0% by weight, in particular 0.05-3.0% by weight, based on the total weight of the preparation. The weight data relate to the composition of the preparation before drying by means of freeze and / or spray drying.

If vitamin A or vitamin A derivatives or carotenes or their derivatives represent the antioxidant or antioxidants, it is advantageous to use their respective concentrations in the range from 0.001 to 30% by weight, based on the total weight of the formulation. to choose. The weight data relate to the composition of the preparation before drying by means of freeze and / or spray drying.

If vitamin E and / or its derivatives represent the antioxidant or antioxidants, it is advantageous to choose their respective concentrations from the range from 0.001 to 30% by weight, based on the total weight of the formulation. The weights relate to the composition of the preparation before drying by means of freeze and / or spray drying.

Further advantageous active ingredients in the sense of the present invention are natural active ingredients and / or their derivatives, such as. B. alpha-lipoic acid, phytoene, D-biotin, coenzyme Q10, alpha-glucosyl rutin, carnitine, carnosine, natural and / or synthetic isoflavonoids, creatine, fumaric acid ester, ectoine and its derivatives, taurine, and / or ß-alanine. These active ingredients can be contained in a concentration of 0.001 to 30% by weight, based on the total weight of the emulsion. The weight data relate to the composition of the preparation before drying by means of freeze and / or spray drying.

Recipes according to the invention, which, for. B. known anti-wrinkle active ingredients such as flavone glycosides (especially α-glycosylrutin), coenzyme Q10, vitamin E and / or derivatives and the like are particularly suitable for the prophylaxis and treatment of cosmetic or dermatological skin changes, such as z. B. occur with skin aging (such as dryness, roughness and formation of dry lines, itching, reduced re-greasing (e.g. after washing), visible vasodilation (telangiectasia, cuperosis), flaccidity and formation of wrinkles and fine lines, local hyper- , Hypo and incorrect pigmentation (e.g. age spots), increased susceptibility to mechanical stress (e.g. cracking) and the like). They are also advantageous against the appearance of dry or rough skin.

However, other pharmaceutically or dermatologically active substances such as, for example, substances that soothe and care for the skin can also be incorporated into the preparations according to the invention. These include, for example, panthenol, allantoin, tannin, antihistamines (e.g. loratadine, cetirizine, dimetionden, clemastine, capsaicin, HR antagonists, tannin preparations), local anesthetics, opiate antagonists (e.g. naltrexone, naloxone), anti-inflammatory drugs, e.g. Plant active ingredients such as azulene and bisabolol, glycyrrhizin, hamamelin and plant extracts such as chamomile, aloe vera, hamazelis, licorice root. The vitamin D ₃ analogues tacalcitol, calcipotriol, tacalcitol, colecalciferol and calcitrol (vitamin D ₃ ) and / or fumaric acid esters can also be successful be incorporated into the preparations.

These active ingredients can be contained in a concentration of 0.001 to 30% by weight, based on the total weight of the emulsion. The weight data relate to the composition of the preparation before drying by means of freeze and / or spray drying.

Advantageous moisturizing or moisturizing agents (so-called moisturizers) for the purposes of the present invention are, for example, glycerol, lactic acid and / or lactates, in particular sodium lactate, butylene glycol, propylene glycol, biosaccaride Gum-1, glycine soybean, ethylhexyloxyglycerol, pyrrolidonecarboxylic acid and urea. Furthermore, it is particularly advantageous to use polymeric moisturizers from the group of water-soluble and / or water-swellable and / or water-gelable polysaccharides. Particularly advantageous are, for example, hyaluronic acid, chitosan and / or a fucose-rich polysaccharide, which is filed in the Chemical Abstracts under the registration number 178463-23-5 and z. B. under the name Fucogel®1000 from the company SOLABIA S.A. is available.

The preparations according to the invention can advantageously contain solid carriers in the form of microfine solid particles. According to the invention, these can advantageously be surface-repellent treated (“gecoatef”), an amphiphilic character of these solid particles being formed or to be retained. The surface treatment can consist in that the solid particles are provided with a thin hydrophobic or hydrophilic layer by methods known per se.

The average particle diameter of the microfine solid carrier used as stabilizer is preferably chosen to be less than 100 μm, particularly advantageously less than 50 μm. It is essentially irrelevant in which form (platelets, rods, beads, etc.) or modification the solid particles used are present.

The microfine solid supports are preferably selected from the group of amphiphilic metal oxide pigments. The following are particularly advantageous: • Titanium dioxides (coated and uncoated): e.g. B. Eusolex T-2000 from Merck, titanium dioxide MT-100 Z from Tayca Corporation

• zinc oxides z. B. Z-Cote and Z-Cote HP1 from BASF AG, MZ-300, MZ-500 and MZ-505M from Tayca Corporation

• iron oxides

Furthermore, it is advantageous if the microfine solid carriers are selected from the following group: boron nitrides, starch derivatives (Tapioca Starch, Sodium Com Starch octynyl succinate etc.), talc, latex particles.

According to the invention, the microfine solid particles are advantageously used in a concentration of 0.5 to 60% by weight, preferably in a concentration of 1 to 50% by weight and particularly preferably in a concentration of 3 to 30% by weight, in each case based on the total weight of the Preparation used. The weight data relate to the composition of the preparation before drying by means of freeze and / or spray drying.

The cosmetic or dermatological preparations according to the invention can furthermore advantageously, although not necessarily, contain fillers which, for. B. further improve the sensory and cosmetic properties of the formulations and, for example, cause or intensify a velvety or silky feeling on the skin. Advantageous fillers for the purposes of the present invention are starch and starch derivatives (such as tapioca starch, distarch phosphate, aluminum or sodium starch, octenyl succinate and the like), pigments which have neither mainly UV filter nor coloring effects (such as e.g. B. boron nitride etc.) and / or Aerosile ^® (CAS No. 7631-86-9).

In addition to the substances mentioned above, the compositions according to the invention optionally contain the additives customary in cosmetics, for example perfume, colorants, antimicrobial substances, refatting agents, complexing and sequestering agents, pearlescent agents, plant extracts, vitamins, active ingredients, preservatives, bactericides, repellents, Self-tanners (e.g. DHA), depigmenting agents (e.g. 8-hexadecen-1,16-dicarboxylic acid (dioic acid, CAS number 20701-68-2; provisional INCI name Octadecendioic acid)), pigments that have a coloring effect, softening, moisturizing and / or moisturizing substances, or other usual components of a cosmetic or dermatological formulation such as emulsifiers, polymers, foam stabilizers, peeling substances (abrasives, e.g. polymer beads or powder made of polyethylene, polypropylene etc. inorganic oxides, silicates etc.), antiperspirant salts (e.g. acidic aluminum and / or aluminum / zirconium salts such as aluminum chlorohydrate and / or aluminum / zirconium chlorohydrate) and electrolytes.

According to the invention, the repellent active ingredients listed below are preferred:

acts as a synergist with various repellents

Particularly advantageous repellent active ingredients for the purposes of the present invention are the active ingredients N, N-diethyl-3-methylbenzamide, 3- (N-n-butyl-N-acetylamino) propionic acid ethyl ester and dimethyl phthalate. The repellent is very particularly preferably ethyl 3- (N-n-butyl-N-acetylamino) propionate.

Embodiments of the emulsion according to the invention which are advantageous according to the invention contain one or more repellent active ingredients in a concentration of 1-50% by weight, based on the total weight of the formulation. The weight data relate to the composition of the preparation before drying by means of freeze and / or spray drying.

According to the invention, the following can advantageously be used as self-tanners: Glycerol aldehyde, hydroxymethylglyoxal, γ-dialdehyde, erythrulose, 6-aldo-D-fructose, ninhydrin, 5-hydroxy-1,4-naphthoquinone (juglone), 2-hydroxy-1,4-naphthoquinone (Lawson) and particularly preferably 1, 3-dihydroxyacetone.

Embodiments which are advantageous according to the invention and have at least one self-tanning substance contain these in a total concentration of 0.1 to 30% by weight, based on the total weight of the emulsion. The weight data relate to the composition of the preparation before drying by means of freeze and / or spray drying.

The emulsion according to the invention can advantageously contain one or more preservatives according to the invention. Advantageous preservatives for the purposes of the present invention are, for example, formaldehyde releasers (such as, for example, DMDM hydantoin, which is available, for example, from Lonza under the trade name Glydant ™), iodopropyl butyl carbamates (for example those under the trade names Glycacil-L, Glycacil -S available from Lonza and / or Dekaben LMB from Jan Dekker), parabens (ie alkyl p-hydroxybenzoate such as methyl, ethyl, propyl and / or butyl paraben), phenoxyethanol, ethanol, benzoic acid and the like. Usually, the preservation system according to the invention also advantageously includes preservation aids, such as, for example, octoxyglycerol, glycine soya, etc. The following table provides an overview of some preservatives which are advantageous according to the invention:

Also useful in cosmetics are preservatives or preservation aids, such as dibromodicyanobutane (2-bromo-2-bromomethylglutarodinitrile), phenoxyethanol, 3-iodo-2-propynylbutylcarbamate, 2-bromo-2-nitro-propane-1,3-diol and imidazolidinyl - urea, 5-chloro-2-methyl-4-isothiazolin-3-one, 2-chloroacetamide, benzalkonium chloride, benzyl alcohol, salicylic acid and salicylates.

It is particularly preferred according to the invention if iodopropyl butyl carbamates, parabens (methyl, ethyl, propyl and / or butyl paraben) and / or phenoxyethanol are used as preservatives.

According to the invention, one or more preservatives are advantageous in a concentration of 2% by weight or less than 2% by weight, preferably 1.5% by weight or less than 1.5% by weight and particularly preferably 1% by weight or less than 1% by weight , each based on the total weight of the preparation. The weight data relate to the composition of the preparation before drying by means of freeze and / or spray drying.

The emulsion according to the invention advantageously contains one or more conditioners. Preferred conditioners according to the invention are, for example, all compounds which are described in Section 4 below in the International Cosmetic Ingredient Dictionary and Handbook (Volume 4, publisher: RC Pepe, JA Wenninger, GN McEwen, The Cosmetic, Toiletry, and Fragrance Association, 9th edition, 2002) the keywords Hair Conditioning Agents, Humectants, Skin-Condftioning Agents, Skin-Conditioning Agents-Emollient, Skin-Conditioning Agents-Humactant, Skin-Conditioning Agents-Miscellaneous, Skin-Conditioning Agents-Occlusive and Skin Protectans are all listed in the EP 0934956 (p.11-13) under water soluble conditioning agent and oil soluble conditioning agent. Some of these compounds are listed under the constituents of the aqueous phase and the oil phase. Further conditioners which are advantageous according to the invention are, for example, the compounds named polyquaternium according to the international nomenclature for cosmetic ingredients (INCI) (in particular polyquaternium-1 to polyquaternium-56). Advantageously according to the invention, the emulsion according to the invention can contain glitter substances and / or other effect substances.

The hydrocolloids which are advantageous according to the invention and which can be used as water-soluble polymers according to the invention are agar agar, carrageenan, tragacanth, gum arabic, alginates, pectins, polyoses, guar flour, locust bean gum, starch, dextrins, polysaccharide-N-alkyl urethanes, inulin carbamates, gelatin, casein, cellulose ethers, hydroxyethyl and propyl cellulose derivatives, polysaccharides, polyacrylic and polymethacrylic compounds, Ammoniumacryloyldime- thyltaurate / vinyl pyrrolidone copolymers and Ammoniumpolyacryl-dimethyltauramide, vinyl polymers, polycarboxylic acids, polyethers, polyimines, polyamides, polysilicic acids, clay minerals, zeolites, silicas used.

An advantageous hydrocolloid for the purposes of the present invention is also xanthan (CAS No. 11138-66-2), also called xanthan gum, which is an anionic heteropolysaccharide which is generally formed from corn sugar by fermentation and is isolated as the potassium salt.

An advantageous hydrocolloid in the sense of the present invention is he carrageenan, a gel-forming and similar to agar extract from north Atlantic, belonging to the florida red algae (Chondrus crispus and Gigartina stellata).

Polyacrylates are also advantageous hydrocolloids to be used in the sense of the present invention. Polyacrylates which are advantageous according to the invention are acrylate-alkyl acrylate copolymers, in particular those which are selected from the group of the so-called carbomers or carbopols (Carbopol® is actually a registered trademark of NOVEON Inc.). In particular, the acrylate-alkyl acrylate copolymers which are advantageous according to the invention are distinguished by the following structure:

R 'represents a long-chain alkyl radical and x and y numbers, which symbolize the respective stoichiometric proportion of the respective comonomers.

According to the invention, preference is given to acrylate copolymers and / or acrylate-alkyl acrylate copolymers which are marketed under the trade names Carbopol® 1382, Carbopol® 981 and Carbopol® 5984, Aqua SF-1 by NOVEON Inc. or as Aculyn® 33 by International Specialty Products Corp. are available. The carbomers Carbopol EDT 2001, ETD 2020 and ETD 2050 are also preferred.

Also advantageous are copolymers of C10-30 alkyl acrylates and one or more monomers of acrylic acid, methacrylic acid or their esters, which are cross-linked with an allyl ether of sucrose or an allyl ether of pentaerythritol.

Compounds which have the INCI name "Acrylates / C 10-30 Alkyl Acrylate Crosspolymer" are advantageous. Those which are available under the trade names Pemulen TR1 and Pemulen TR2 from NOVEON Inc. are particularly advantageous.

Compounds which carry the INCI-AcrylatesΛ / inyl isodecanoate crosspolymer "are advantageous. Particularly advantageous are those available from 3V Sigma under the trade names Stabylen 30.

Also advantageous are compounds which have the INCI name "acrylates / C12-24 pareth-25 acrylate copolymer" (available under the trade names Synthalen® W2000 from 3V Inc.) and the INCI name "acrylates / steareth-20 methacrylate copolymer""(available under the trade names Aculyn® 22 from International Specialty Products Corp.), the INCI name" acrylates / steareth-20 itaconate copolymer "(available under the trade names Structure 2001® from National Starch), the INCI Name "acrylates / aminoacrylates / C 10-30 alkyl PEG-20 itaconate copolymer "(available under the trade names Structure Plus® from National Starch) and similar polymers.

According to the invention, it is particularly preferred to use neutralized or partially neutralized polyacrylates (e.g. Carbopole from Noveon).

The cosmetic and / or dermatological emulsions according to the invention can contain a number of pigments.

The dyes and pigments can be selected from the corresponding positive list in the Cosmetics Ordinance or the EC list of cosmetic colorants. In most cases, they are identical to the colorants approved for food. Advantageous color pigments are, for example, titanium dioxide, mica, iron oxides (e.g. Fe 0 ₃ , Fβ ₃ θ, FeO (OH)) and / or tin oxide. Advantageous dyes are, for example, carmine, Berlin blue, chrome oxide green, ultramarine blue and / or manganese violet. It is particularly advantageous to choose the dyes and / or color pigments from the list below. The Color Index Numbers (CIN) are taken from the Rowe Color Index, 3rd edition, Society of Dyers and Colorists, Bradford, England, 1971.

Chemical or other name CIN color

Pigment Green 10006 Green

Acid Green 1 10020 Green

2,4-dinitrohydroxynaphthalene-7-sulfonic acid 10316 yellow

Pigment Yellow 1 11680 yellow

Pigment Yellow 3 11710 yellow

Pigment Orange 1 11725 Orange

2,4-dihydroxyazobenzene 11920 orange

Solvent Red 3 12010 Red

1 - (2'-chloro-4'-nitro-1 '-phenylazo) -2-hydroxynaphthalene 12085 red

Pigment Red 3 12120 red

Ceresrot; Sudan Red; Fat red G 12150 red

Pigment Red 112 12370 Red

Pigment Red 7 12420 red

Pigment Brown 1 12480 Brown

4- (2'-Methoxy-5'-sulfonic acid diethylamide-1'-phenylazo) -3-hy- 12490 red hydroxy-5 "-chloro-2", 4 "-dimethoxy-2-naphthoic acid anilide

Disperse Yellow 16 12700 Yellow

1 - (4-Sulfo-1-phenylazoH-amino-benzene-δ-sulfonic acid 13015 yellow

2,4-Dihydroxy _^ azobenzene-4'-sulfonic acid 14270 orange

2- (2,4-dimethylphenylazo-5-sulfonic acid) -1-hydroxynaphthalene-14700 red

4-sulfonic acid

2- (4-sulfo-1-naphthylazo) -1 -naphthol-4-sulfonic acid 14720 red

2- (6-sulfo-2,4-xylylazo) -1-naphthol-5-sulfonic acid 14815 red

1- (4'-Sulfophenylazo) -2-hydroxynaphthalene 15510 orange Chemical or other name CIN color

1 - (2-sulfonic acid-4-chloro-5-carboxylic acid-1-phenylazo) -2- 15525 red hydroxynaphthalene

1- (3-methyl-phenylazo-4-sulfonic acid) -2-hydroxynaphthalene 15580 red

1- (4 ', (8') - sulfonic acid naphthylazo) -2-hydroxynaphthalene 15620 red

2-hydroxy-1, 2'-azonaphthalene-1 'sulfo acid 15630 red

3-Hydroxy-4-phenylazo-2-naphthylcarboxylic acid 15800 red

1 - (2-Sulfo-4-methyl-1-phenylazo) -2-naphthylcarboxylic acid 15850 red

1 - (2-Sulfo-4-methyl-5-chloro-1-phenylazo) -2-hydroxy- 15865 red naphthalene-3-carboxylic acid

1 - (2-sulfo-1-naphthylazo) -2-hydroxynaphthalene-3-carboxylic acid 15880 red

1 - (3-Sulfo-1-phenylazo) -2-naphthol-6-sulfonic acid 15980 orange

1 - (4-Sulfo-1-phenylazo) -2-naphthol-6-sulfonic acid 15985 yellow

Allura Red 16035 red

1 - (4-Sulfo-1-naphthylazo) -2-naphthol-3,6-disulfonic acid 16185 red

Acid Orange 10 16230 Orange

1 - (4-Sulfo-1-naphthylazo) -2-naphthol-6,8-disulfonic acid 16255 red

1 - (4-Sulfo-1-naphthylazo) -2-naphthol-3,6,8-trisulfonic acid 16290 red

8-amino-2-phenylazo-1-naphthol-3,6-disulfonic acid 17200 red

Acid Red 1 18050 Red

Acid Red 155 18 130 Red

Acid Yellow 121 18690 yellow

Acid Red 180 18736 Red

Acid Yellow 11 18820 Yellow

Acid Yellow 17 18965 yellow

4- (4-Sulfo-1-phenylazo) -1 - (4-sulfophenyl) -5-hydroxy-19140 yellow pyrazolone-3-carboxylic acid

Pigment Yellow 16 20040 yellow

2,6- (4'-sulfo-2 ", 4" -dimethyl) bis-phenylazo) 1, 3-dihydroxy- 20170 orange benzene

Acid Black 1 20470 Black

Pigment Yellow 13 21 100 yellow

Pigment Yellow 83 21 108 Yellow

Solvent Yellow 21230 yellow

Acid Red 163 24790 Red

Acid Red 73 27 290 Red

2- [4 '- (4 "-sulfo-1" -phenylazo) -7'-sulfo-1' -naphthylazo] -1 - 27755 black hydroxy-7-aminonaphthalene-3,6-disulfonic acid

4 '- [(4 "-sulfo-1" -phenylazo) -7'-sulfo-1' -naphthylazo] -1 -hydroxy- 28440 black

8-acetyl-aminonaphthalene-3,5-disulfonic acid

Direct Orange 34, 39, 44, 46, 60 40215 Orange

Food Yellow 40800 orange trans-beta-apo-8'-Carotinaldehyd (C30) 40820 orange trans-Apo-8'-carotene acid (C ₃ o) ethyl ester 40825 orange

Canthaxanthin 40850 orange

Acid Blue 1 42045 Blue

2,4-disulfo-5-hydroxy-4'-4 "-bis- (diethylamino) triphenyl- 42051 blue carbinol

4 - [(- 4-N-ethyl-p-sulfobenzylamino) phenyl- (4-hydroxy-2-sulfo-42053 green phenyl) - (methylene) -1- (N-ethylN-p-sulfobenzyl) -2, 5 Chemical or other name CIN color cyclohexadienimine]

Acid Blue 7 42080 Blue

(N-ethyl-p-sulfobenzylamino) phenyl- (2-sulfophenyl) - 42090 blue methylene- (N-ethyl-Np-sulfobenzyl) Δ ^2, -cyclohexadienimine

Acid Green 9 42 100 Green

Diethyl-di-sulfobenzyl-di-4-amino-2-chloro-di-2-methyl- 42170 green foxsonmonium

Basic Violet 14 42510 Violet

Basic Violet 2 42520 Violet

2'-Methyl-4 '- (N-ethyl-N-m-sulfobenzyl) -amino-4 "- (N-diethyl) - 42735 Blue amino-2-methyl-N-ethylN-m-sulfobenzyl-fuchsonimmonium

4 '- (N-Dimethyl) -amino-4 "- (N-phenyl) -aminonaphtho-N- 44045 blue dimethyl-fuchsonimmonium

2-hydroxy-3,6-disulfo-4,4'-bis-dimethylamino- 44090 green naphthofuchsonimmonium

Acid Red 52 45 100 Red

3- (2'-Methylphenylamino) -6- (2'-methyl-4'-sulfophenylamino) - 45190 Violet

9- (2 'carboxyphenyl) -xantheniumsalz

Acid Red 50 45 220 Red

Phenyl-2-oxyfluoron-2-carboxylic acid 45350 yellow

4,5-dibromofluorescein 45370 orange

2,4,5,7-tetrabromofluorescein 45380 red

Solvent Dye 45396 Orange

Acid Red 98 45405 Red

3 ', 4', 5 ', 6'-tetrachloro-2,4,5,7-tetrabromofluorescein 45410 red

4,5-diiodofluorescein 45425 red

2,4,5,7-tetraiodofluorescein 45430 red

Quinophthalone 47000 yellow

Quinophthalone disulfonic acid 47005 yellow

It may also be favorable to choose one or more substances from the following group as the dye: 2,4-dihydroxyazobenzene, 1- (2'-chloro-4'-nitro-1'-phenylazo) -2-hydroxynaphthalene, ceres red, 2- (4-sulfo-1-naphthylazo) -1 -naphthol-4-sulfonic acid, calcium salt of 2-hydroxy-1,2 "azonaphthalene-1 '-'ulfonic acid, calcium and barium salts of 1- (2- Sulfo-4-methyl-1-phenylazo) -2-naphthylcarboxylic acid, calcium salt of 1- (2-surfo-1-naphthylazo) -2-hydroxynaphthalene-3-carboxylic acid, aluminum salt of 1- (4-sulfo-1-phenylazo) -2-naphthol-6-sulfonic acid, aluminum salt of 1- (4-sulfo-1-naphthylazo) -2-naphthol-3,6-disulfonic acid, 1 - (4-surfo-1-naphthylazo) -2-naphthol-6 , 8-disulfonic acid, aluminum salt of 8-amino-2-phenylazo-1-naphthol-3,6-disurfonic acid, aluminum salt of 4- (4-sulfo-1-phenylazo) -1- (4-sulfophenyl) -5-hydroxy -pyrazolone-3-carboxylic acid, 4 '- [(4 "-sulfo-1" -phenylazo) -7'-sulfo-1' -naphthylazo] -1 -hydroxy-8-acetylaminonaphthalene-3,5-disulfonic acid, Aluminum and zirconium salts of 4.5 -Dibromofluorescein, aluminum and zirconium salts of 2,4,5,7-tetrabromofluorescein, 3 "4" 5 "6" Te- trachloro-2,4,5,7-tetrabromofluorescein and its aluminum salt, aluminum salt of 2,4,5,7-tetraiodofluorescein, aluminum salt of quinophthalone disulfonic acid, aluminum salt of indigo disulfonic acid, 4,4'-di'ethyl-6, 6'-di'hlorthioindigo, complex salt (Na, Al, Ca) of carminic acid, red and black iron oxide (CIN: 77491 (red) and 77499 (black)), iron oxide hydrate (CIN: 77 492), manganese ammonium diphosphate (CIN 77745), Ultramarine (CIN 77007) and titanium dioxide.

Emulsions according to the invention can contain titanium dioxides, which can be present both in the rutile and anatase crystal modification and, for the purposes of the present invention, are advantageously surface-treated (“gecoatef”), for example a hydrophilic, amphiphilic or hydrophobic character is to be formed or retained. This surface treatment can consist in that the pigments are provided with a thin hydrophilic and / or hydrophobic inorganic and / or organic layer by methods known per se. For the purposes of the present invention, the various surface coatings can also contain water.

Inorganic surface coatings in the sense of the present invention can consist of aluminum oxide (Al ₂ 0 ₃ ), aluminum hydroxide Al (OH) ₃ , or aluminum oxide hydrate (also: alumina, CAS no .: 1333-84-2), sodium hexametaphosphate (NaP0 ₃ ) ₆ , sodium metaphosphate (NaP0 ₃ ) _n , silicon dioxide (Si0 ₂ ) (also: silica, CAS No .: 7631-86-9), zirconium oxide (Zr0 ₂ ) or iron oxide (Fβ2θ ₃ ). These inorganic surface coatings can occur alone, in combination and / or in combination with organic coating materials.

For this purpose, oxides, oxide hydrates or phosphates, for example of the elements Al, Si, Zr, are struck in dense layers on the pigment surface.

The inorganic aftertreatment generally takes place in an aqueous suspension of the pigment by adding soluble aftertreatment chemicals, such as, for example, aluminum sulfate, and then precipitating the hydroxide, which is sparingly soluble in the neutral range, by specifically adjusting the pH with sodium hydroxide solution. After the inorganic aftertreatment, the coated pigments are separated from the suspension by filtration and washed carefully to remove the dissolved salts, and then the isolated pigments are dried. For the purposes of this invention, particular preference is given to titanium dioxides to which aluminum hydroxide has been applied to the surface, such as, for example, titanium dioxide types C47-051 and C47- 5175 available from Sun Chemical. Further preferred pigments are titanium dioxides containing aluminum and / or silicon oxides are coated, such as from Krosnos Titan: Kronos 1071 and 1075 or from Kingfisher: A310.03 Tudor Aspen.

Organic surface coatings in the sense of the present invention can consist of vegetable or animal aluminum stearate, vegetable or animal stearic acid, lauric acid, dimethylpolysiloxane (also: dimethicone), methylpolysiloxane (methicone), simethicone (a mixture of dimethylpolysiloxane with an average chain length of 200 to 350 dimethylsiloxane Units and silica gel) or alginic acid. These organic surface coatings can occur alone, in combination and / or in combination with inorganic coating materials.

Furthermore, it can be advantageous to use pearlescent pigments according to the invention. These include natural pearlescent pigments such as B.

"Fish silver" (guanine / hypoxanthine mixed crystals from fish scales) and

"Mother-of-pearl" (milled mussel shells),

monocrystalline pearlescent pigments such as B. bismuth oxychloride (BiOCI), layer-substrate pigments: e.g. B. mica / metal oxide

Pearlescent pigments are based, for example, on powdered pigments or castor oil dispersions of bismuth oxychloride and / or titanium dioxide and bismuth oxychloride and / or titanium dioxide on mica. Particularly advantageous is e.g. B. the gloss pigment listed under CIN 77163.

The following pearlescent pigment types based on mica / metal oxide are also advantageous:

The pearlescent pigments available from Merck under the trade names Timiron, Colorona or Dichrona are particularly preferred.

The list of the pearlescent pigments mentioned is of course not intended to be limiting. Pearlescent pigments which are advantageous in the sense of the present invention can be obtained in numerous ways known per se. For example, other substrates besides mica can be coated with other metal oxides, such as. B. silica and the like. Z are advantageous. B. with Ti0 ₂ and Fe ₂ θ3 coated Si0 ₂ particles ("Ronaspheren"), which are sold by Merck.

It can also be advantageous to completely do without a substrate such as mica. Pearlescent pigments which are produced using SiO ₂ are particularly preferred. Such pigments, which can also have gonichromatic effects, are e.g. B. available under the trade name Sicopearl Fantastico from BASF.

Pigments from Engelhard / Mearl based on calcium sodium borosilicate, which are coated with titanium dioxide, can also be used advantageously. These are available under the name Reflecks. Due to their particle size of 40 - 180 μm, they have a glitter effect in addition to the color.

The dyes and pigments can be present both individually and in a mixture and can be mutually coated, different color effects generally being produced by different coating thicknesses. The The total amount of dyes and coloring pigments is advantageously from the range of z. B. 0.1 wt .-% to 30 wt .-%, preferably from 0.5 to 15 wt .-%, in particular from 1.0 to 10 wt .-%, each based on the total weight of the preparations. The weight data relate to the composition of the preparation before drying by means of freeze and / or spray drying.

The O / W emulsion according to the invention advantageously contains one or more tablet auxiliaries. According to the invention, these can advantageously be in a concentration of 0.1 to 60% by weight, preferably in a concentration of 1 to 50% by weight and very particularly preferably in a concentration of 3 to 35% by weight, in each case based on the total weight of the preparation be used. The weight data relate to the composition of the preparation, the preparation being considered to be the emulsion after freeze and / or spray drying, together with any other water-soluble and / or volatile compounds and tableting materials (including hydrogen carbonates and acids which are solid at room temperature).

For example, fillers and compacting aids (e.g. starch and / or cellulose derivatives), flow agents (e.g. highly disperse silicon dioxide), flow control agents, lubricants, mold release agents can be used as tablet auxiliaries.

Advantageously according to the invention, all substances can be used that are in the H.P. Fiedler, Lexicon of auxiliaries for pharmacy, cosmetics and related areas, 5th edition, Editio Cantor Verlag, Aulendorf, 2002, under the keywords tablet binders, tablet fillers, tablet lubricants, tablet auxiliaries, tablet disintegrants, tablet Coatings are listed.

In a particularly preferred embodiment according to the invention, the preparation according to the invention contains a combination of carbonates and / or hydrogen carbonates and acids which are solid at room temperature (for example citric acid, ascorbic acid, lactic acid, tartaric acid, etc.). Strongly swelling polymers such as crosslinked polyvinylpyrrolidone can also be used advantageously according to the invention. According to the invention, one or more hydrogen carbonates (for example sodium hydrogen carbonate, potassium hydrogen carbonate) are advantageous in an amount of 0.1 to 30% by weight, preferably in an amount of 0.5 to 20% by weight and particularly preferably in an amount of 0.5 to 15% by weight, based in each case on the total weight of the preparation, the emulsion being the preparation after the freeze and / or spray drying together with evi. other water-soluble and / or and / or volatile compounds and tableting materials (including hydrogen carbonates and acids solid at room temperature) is considered.

According to the invention, one or more acids which are solid at room temperature (particularly preferably citric acid) are advantageous in an amount of 0.1 to 30% by weight, preferably in an amount of 0.5 to 20% by weight and particularly preferably in an amount of 0, 5 to 15% by weight, based in each case on the total weight of the preparation, the emulsion being used after the freeze and / or spray drying together with any further water-soluble and / or volatile compounds and tableting materials (including hydrogen carbonates and solid at room temperature) Acids) is considered.

Such an embodiment is particularly advantageous in the sense of the present invention if the emulsion according to the invention is in the form of a tablet (e.g. an effervescent tablet), since the emulsion according to the invention in this embodiment is particularly easy to re-emulsify by adding water.

According to the invention is also the method for producing such a preparation, which is characterized in that the O / W emulsion according to the invention are mixed with one or more tablet auxiliaries in a mixing device.

Preparations which are produced by this process according to the invention are also according to the invention.

According to the invention is also a method for producing tablets and / or granules, which is characterized in that an inventive Preparation is pressed or granulated in a press to form one or more tablets, and preparations which are produced by this process.

Last but not least, the process for producing a cosmetic is according to the invention, which is characterized in that a preparation according to the invention (an O / W emulsion dried by spray drying and / or freeze drying, optionally with water-soluble and / or volatile active ingredients, auxiliary additives and / or tablet auxiliaries are added and, if appropriate, was tableted or granulated) is mixed with water or emulsified in water. Cosmetics which are produced by this method are also according to the invention.

Such a cosmetic according to the invention is then in the form of an ointment, cream, lotion or an emulsion foam (French mousse) or a sprayable form. According to the invention, it can advantageously be used for the treatment and care of the skin, hair and nails. According to the invention, use as a sunscreen is preferred.

The following examples are intended to illustrate the present invention without restricting it. Unless otherwise stated, all quantities, parts and percentages are based on the weight and the total amount or on the total weight of the preparations.

According to the invention, the examples from Table 1 (emulsion preparations after spray drying) are mixed homogeneously with mixtures of the water-soluble and dispersible additives (Table 2).

Optionally, the substance mixtures (Tables 1 + 2) can be mixed with tableting and granulating aids (Table 3) and granules and / or tablets according to the invention can be produced by suitable processes. Examples:

Table 1: Emulsion preparation after spray or freeze drying

Claims

claims

1. A process for producing an O / W emulsion, characterized in that an O / W emulsion containing a) a lipid phase in a concentration of 20 to 95% by weight, b) one or more water-soluble polymers in a total concentration of 1 up to 80% by weight, in each case based on the total weight of the preparation, and c) one or more UV light protection filters and d) an aqueous phase, in addition to any other cosmetic and / or dermatological active ingredients, auxiliaries and additives, by spray drying and / or freeze drying.

2. O / W emulsion produced by a process according to claim 1.

3. A process for producing an O / W emulsion, characterized in that an O / W emulsion according to one of claims 1 or 2 is mixed in a mixing device with water-soluble and / or volatile active ingredients, auxiliaries and / or additives.

4. O / W emulsion produced by a method according to claim 3.

5. Preparation containing an O / W emulsion according to one of claims 2 or 4 and one or more granulating and / or tablet auxiliaries.

6. A method for producing a preparation according to claim 5, characterized in that an O / W emulsion according to one of claims 2 or 4 is mixed with one or more tablet excipients in a mixing device.

7. Preparation prepared by a method according to claim 6.

8. A process for the production of tablets and / or granules, characterized in that a preparation according to claim 7 is pressed in a press to form one or more tablets or granulated by means of suitable granulating devices.

9. Preparation produced by a method according to claim 8.

10. A method for producing a cosmetic, characterized in that a preparation according to one of claims 2, 4, 5, 7 and / or 9 are mixed with water.

11. Cosmetic manufactured by a method according to claim 10.